The objective of this study is to examine the prevalence of musculoskeletal disorders(MSDs) among nursing personnels. A self-reporting survey adapted from Nordic questionnaires was used as diagnostic tool, and conducted for 162 nurses working for a general hospital. The survey was performed five times every three months during a year. The MSDs were defined by using three criteria, depending upon the frequency, duration and pain intensity of the symptoms. The results showed that the 12-month prevalences of MSDs at any body site by criterion 1, 2, 3 were 56.8%, 53.7%, 45.7%, respectively, and that the shoulder was the most susceptible to MSDs, followed by knee/lower leg, lower back, hand/wrist, neck, ankle/feet, finger, etc. Only one statistically significant risk factor of departments or units was identified through the Chi-square test. The prevalence of MSDs was the highest in intensive care unit, second in surgical ward, while the prevalence was the lowest in emergency room. The MSDs prevalence of Korea at any body part or by body part was much lower than that of foreign countries such as Japan, USA, Sweden, etc. This implies that when considering poor working conditions and load in Korea, the incidence rate of MSDs may rapidly increase in Korea in the future.