In this paper, we introduce and study generalized mixed operator quasi-equilibrium problems(GMQOEP) in Hausdorff topological vector spaces and prove the existence results for the solution of (GMQOEP) in compact and noncompact settings by employing 1-person game theorems. Moreover, using coercive condition, hemicontinuity of the functions and KKM theorem, we prove new results on the existence of solution for the particular case of (GMQOEP), that is, generalized mixed operator equilibrium problem (GMOEP).