• Title/Summary/Keyword: cell-to-cell communication

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Superficial Esophageal Cancer Treated with Multidisciplinary Care: A Case Report (다학제 접근을 통해 치료에 성공한 표재성 식도암 1례)

  • Oh, Gyu Man;Park, Moo In;Jung, Kyoung Won;Kang, Sung Min;Son, Min Young;Kim, Jae Hyun;Moon, Won;Park, Seun Ja
    • Journal of Digestive Cancer Research
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    • v.8 no.1
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    • pp.71-75
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    • 2020
  • Esophageal cancer is easy to infiltrate and metastasize because esophagus does not have serosa, and is difficult to remove it because esophagus is in the middle of the chest. Because of this, treatments of esophageal cancer do not always follow the guideline. In this situation, efforts to increase treatment efficiency and improve survival rate through multidisciplinary treatment are increasing. In this case, we report the patient with three superficial esophageal cancers (one in cervical esophagus and two in thoracic esophagus). The patient was treated with concurrent chemoradiotherapy instead of surgery through multidisciplinary discussion. The patient reached a complete remission through this discussion. This case is intended to inform the usefulness of multidisciplinary treatment in patients with esophageal cancer.

A small-area implementation of public-key cryptographic processor for 224-bit elliptic curves over prime field (224-비트 소수체 타원곡선을 지원하는 공개키 암호 프로세서의 저면적 구현)

  • Park, Byung-Gwan;Shin, Kyung-Wook
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.21 no.6
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    • pp.1083-1091
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    • 2017
  • This paper describes a design of cryptographic processor supporting 224-bit elliptic curves over prime field defined by NIST. Scalar point multiplication that is a core arithmetic function in elliptic curve cryptography(ECC) was implemented by adopting the modified Montgomery ladder algorithm. In order to eliminate division operations that have high computational complexity, projective coordinate was used to implement point addition and point doubling operations, which uses addition, subtraction, multiplication and squaring operations over GF(p). The final result of the scalar point multiplication is converted to affine coordinate and the inverse operation is implemented using Fermat's little theorem. The ECC processor was verified by FPGA implementation using Virtex5 device. The ECC processor synthesized using a 0.18 um CMOS cell library occupies 2.7-Kbit RAM and 27,739 gate equivalents (GEs), and the estimated maximum clock frequency is 71 MHz. One scalar point multiplication takes 1,326,985 clock cycles resulting in the computation time of 18.7 msec at the maximum clock frequency.

A Unified ARIA-AES Cryptographic Processor Supporting Four Modes of Operation and 128/256-bit Key Lengths (4가지 운영모드와 128/256-비트 키 길이를 지원하는 ARIA-AES 통합 암호 프로세서)

  • Kim, Ki-Bbeum;Shin, Kyung-Wook
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.21 no.4
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    • pp.795-803
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    • 2017
  • This paper describes a dual-standard cryptographic processor that efficiently integrates two block ciphers ARIA and AES into a unified hardware. The ARIA-AES crypto-processor was designed to support 128-b and 256-b key sizes, as well as four modes of operation including ECB, CBC, OFB, and CTR. Based on the common characteristics of ARIA and AES algorithms, our design was optimized by sharing hardware resources in substitution layer and in diffusion layer. It has on-the-fly key scheduler to process consecutive blocks of plaintext/ciphertext without reloading key. The ARIA-AES crypto-processor that was implemented with a $0.18{\mu}m$ CMOS cell library occupies 54,658 gate equivalents (GEs), and it can operate up to 95 MHz clock frequency. The estimated throughputs at 80 MHz clock frequency are 787 Mbps, 602 Mbps for ARIA with key size of 128-b, 256-b, respectively. In AES mode, it has throughputs of 930 Mbps, 682 Mbps for key size of 128-b, 256-b, respectively. The dual-standard crypto-processor was verified by FPGA implementation using Virtex5 device.

Low Complexity Channel Preprocessor for Multiple Antenna Communication Systems (다중 안테나 통신 시스템을 위한 저복잡도 채널 전처리 프로세서)

  • Hwang, You-Sun;Jang, Soo-Hyun;Han, Chul-Hee;Choi, Sung-Nam;Jung, Yun-Ho
    • Journal of Advanced Navigation Technology
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    • v.15 no.2
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    • pp.213-220
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    • 2011
  • In this paper, the channel preprocessor with an area-efficient architecture is proposed for the MIMO symbol detector which can support four transmit and receive antennas. The proposed channel preprocessor can shrink the channel dimension to reduce the hardware complexity of the MIMO symbol detector. Also, the proposed channel preprocessor is implemented with very low complexity by using QR decomposition (QRD) and log-number system (LNS). By applying QRD and LNS to the nulling matrix calculation block, the numbers of matrix-multiplications and matrix-divisions are decreased and thus the complexity of the proposed channel preprocessor is significantly reduced. The proposed channel preprocessor was designed in a hardware description language (HDL) and synthesized to gate-level circuits using 0.13um CMOS standard cell library. With the proposed channel preprocessor, the number of logic gates for channel preprocessor is reduced by 20.2% compared with the conventional architecture.

Study of Low Reflectance and RF Frequency by Rie Surface Texture Process in Multi Crystall Silicon Solar Cells (공정가스와 RF 주파수에 따른 웨이퍼 표면 텍스쳐 처리 공정에서 저반사율에 관한 연구)

  • Yun, Myoung-Soo;Hyun, Deoc-Hwan;Jin, Beop-Jong;Choi, Jong-Young;Kim, Joung-Sik;Kang, Hyoung-Dong;Yi, Jun-Sin;Kwon, Gi-Chung
    • Journal of the Korean Vacuum Society
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    • v.19 no.2
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    • pp.114-120
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    • 2010
  • Conventional surface texturing in crystalline silicon solar cell have been use wet texturing by Alkali or Acid solution. But conventional wet texturing has the serious issue of wafer breakage by large consumption of wafer in wet solution and can not obtain the reflectance below 10% in multi crystalline silicon. Therefore it is focusing on RIE texturing, one method of dry etching. We developed large scale plasma RIE (Reactive Ion Etching) equipment which can accommodate 144 wafers (125 mm) in tray in order to provide surface texturing on the silicon wafer surface. Reflectance was controllable from 3% to 20% in crystalline silicon depending on the texture shape and height. We have achieved excellent reflectance below 4% on the weighted average (300~1,100 nm) in multi crystalline silicon using plasma texturing with gas mixture ratio such as $SF_6$, $Cl_2$, and $O_2$. The texture shape and height on the silicon wafer surface have an effect on gas chemistry, etching time, RF frequency, and so on. Excellent conversion efficiency of 16.1% is obtained in multi crystalline silicon by RIE process. In order to know the influence of RF frequency with 2 MHz and 13.56 MHz, texturing shape and conversion efficiency are compared and discussed mutually using RIE technology.

Design of Low-Noise and High-Reliability Differential Paired eFuse OTP Memory (저잡음 · 고신뢰성 Differential Paired eFuse OTP 메모리 설계)

  • Kim, Min-Sung;Jin, Liyan;Hao, Wenchao;Ha, Pan-Bong;Kim, Young-Hee
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.17 no.10
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    • pp.2359-2368
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    • 2013
  • In this paper, an IRD (internal read data) circuit preventing the reentry into the read mode while keeping the read-out DOUT datum at power-up even if noise such as glitches occurs at signal ports such as an input signal port RD (read) when a power IC is on, is proposed. Also, a pulsed WL (word line) driving method is used to prevent a DC current of several tens of micro amperes from flowing into the read transistor of a differential paired eFuse OTP cell. Thus, reliability is secured by preventing non-blown eFuse links from being blown by the EM (electro-migration). Furthermore, a compared output between a programmed datum and a read-out datum is outputted to the PFb (pass fail bar) pin while performing a sensing margin test with a variable pull-up load in consideration of resistance variation of a programmed eFuse in the program-verify-read mode. The layout size of the 8-bit eFuse OTP IP with a $0.18{\mu}m$ process is $189.625{\mu}m{\times}138.850{\mu}m(=0.0263mm^2)$.

A Design of PRESENT Crypto-Processor Supporting ECB/CBC/OFB/CTR Modes of Operation and Key Lengths of 80/128-bit (ECB/CBC/OFB/CTR 운영모드와 80/128-비트 키 길이를 지원하는 PRESENT 암호 프로세서 설계)

  • Kim, Ki-Bbeum;Cho, Wook-Lae;Shin, Kyung-Wook
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.20 no.6
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    • pp.1163-1170
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    • 2016
  • A hardware implementation of ultra-lightweight block cipher algorithm PRESENT which was specified as a standard for lightweight cryptography ISO/IEC 29192-2 is described. The PRESENT crypto-processor supports two key lengths of 80 and 128 bits, as well as four modes of operation including ECB, CBC, OFB, and CTR. The PRESENT crypto-processor has on-the-fly key scheduler with master key register, and it can process consecutive blocks of plaintext/ciphertext without reloading master key. In order to achieve a lightweight implementation, the key scheduler was optimized to share circuits for key lengths of 80 bits and 128 bits. The round block was designed with a data-path of 64 bits, so that one round transformation for encryption/decryption is processed in a clock cycle. The PRESENT crypto-processor was verified using Virtex5 FPGA device. The crypto-processor that was synthesized using a $0.18{\mu}m$ CMOS cell library has 8,100 gate equivalents(GE), and the estimated throughput is about 908 Mbps with a maximum operating clock frequency of 454 MHz.

A single-memory based FFT/IFFT core generator for OFDM modulation/demodulation (OFDM 변복조를 위한 단일 메모리 구조의 FFT/IFFT 코어 생성기)

  • Yeem, Chang-Wan;Jeon, Heung-Woo;Shin, Kyung-Wook
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2009.05a
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    • pp.253-256
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    • 2009
  • This paper describes a core generator (FFT_Core_Gen) which generates Verilog HDL models of 8 different FFT/IFFT cores with $N=64{\times}2^k$($0{\leq}k{\leq}7$ for OFDM-based communication systems. The generated FFT/IFFT cores are based on in-place single memory architecture, and use a hybrid structure of radix-4 and radix-2 DIF algorithm to accommodate various FFT lengths. To achieve both memory reduction and the improved SQNR, a conditional scaling technique is adopted, which conditionally scales the intermediate results of each computational stage, and the internal data and twiddle factor has 14 bits. The generated FFT/IFFT cores have the SQNR of 58-dB for N=8,192 and 63-dB for N=64. The cores synthesized with a $0.35-{\mu}m$ CMOS standard cell library can operate with 75-MHz@3.3-V, and a 8,192-point FFT can be computed in $762.7-{\mu}s$, thus the cores satisfy the specifications of wireless LAN, DMB, and DVB systems.

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Design of eFuse OTP Memory with Wide Operating Voltage Range for PMICs (PMIC용 넓은 동작전압 영역을 갖는 eFuse OTP 설계)

  • Jeong, Woo-Young;Hao, Wen-Chao;Ha, Pan-Bong;Kim, Young-Hee
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.1
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    • pp.115-122
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    • 2014
  • In this paper, reliability is secured by sensing a post-program resistance of several tens of kilo ohms and restricting a read current flowing over an unblown eFuse within $100{\mu}A$ since RWL driver and BL pull-up load circuits using a regulated voltage of V2V ($=2V{\pm}10%$) are proposed to have a wide operating voltage range for eFuse OTP memory. Also, when a comparison of a cell array of 1 row ${\times}$ 32 columns with that of 4 rows ${\times}$ 8 columns is done, the layout size of 4 rows ${\times}$ 8 columns is smaller with $187.065{\mu}m{\times}94.525{\mu}m$ ($=0.01768mm^2$) than that of 1 row ${\times}$ 32 columns with $735.96{\mu}m{\times}61.605{\mu}m$ ($=0.04534mm^2$).

Dual-mode Pseudorandom Number Generator Extension for Embedded System (임베디드 시스템에 적합한 듀얼 모드 의사 난수 생성 확장 모듈의 설계)

  • Lee, Suk-Han;Hur, Won;Lee, Yong-Surk
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.46 no.8
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    • pp.95-101
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    • 2009
  • Random numbers are used in many sorts of applications. Some applications, like simple software simulation tests, communication protocol verifications, cryptography verification and so forth, need various levels of randomness with various process speeds. In this paper, we propose a fast pseudorandom generator module for embedded systems. The generator module is implemented in hardware which can run in two modes, one of which can generate random numbers with higher randomness but which requires six cycles, the other providing its result within one cycle but with less randomness. An ASIP (Application Specific Instruction set Processor) was designed to implement the proposed pseudorandom generator instruction sets. We designed a processor based on the MIPS architecture,, by using LISA, and have run statistical tests passing the sequence of the Diehard test suite. The HDL models of the processor were generated using CoWare's Processor Designer and synthesized into the Dong-bu 0.18um CMOS cell library using the Synopsys Design Compiler. With the proposed pseudorandom generator module, random number generation performance was 239% faster than software model, but the area increased only 2.0% of the proposed ASIP.