• Title/Summary/Keyword: CsA

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Antioxidant and Anti-inflammatory Properties of Two Extracts from Lycium ruthenicum Murray Fruit (흑구기자 열매의 생리활성 평가 연구)

  • Zou, Jie;Lee, Ji-An
    • Journal of Convergence for Information Technology
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    • v.11 no.5
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    • pp.190-198
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    • 2021
  • The aim of the study was to evaluate the physiological activity of Lycium ruthenicum to investigate their potential as a raw material that can be used in the cosmetic industry. L. ruthenicum fruit extracts were obtained using 70% methanol(LRM) and hot-water(LRW). The DPPH and ABTS radical scavenging abilities were higher in the LRM extract than in the LRW extract. The FRAP value of LRM was about 1.3-fold greater than that of LRW. The polyphenol contents of LRM and LRW were 31.883±1.395 mg/g and 27.748±2.741 mg/g respectively. LRM inhibited the generation of NO in LPS-stimulated RAW264.7 cells. LRM also attenuated the expression of COX-2, PGE2, IL-6, and TNF-α induced by LPS. These results suggests that L. ruthenicum fruits could be use as a source of natural antioxidants and anti-inflammatory agent in cosmetic products.

Relationship between Flexibility Exercise and Health-Related Quality of Life and Oral Health: Using the National Health and Nutrition Examination Survey 2012 Years (유연성 운동과 건강관련 삶의 질 및 구강건강과의 관련성: 국민건강영양조사 2012년도 자료를 활용하여)

  • Kim, Yu-Rin
    • Journal of Convergence for Information Technology
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    • v.11 no.12
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    • pp.265-274
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    • 2021
  • The purpose of this study is to provide basic data for confirming the convergence relationship between flexibility exercise on quality of life, oral condition, and oral health-related behavior. Data from the 2012 KNHNES were used, and complex sample linear regression analysis and logistic regression analysis were performed to confirm the effects of flexibility exercise on quality of life and oral health. As a result, those who controlled for demographic characteristics and did not exercise flexibility had .027 times worse exercise ability among the subcategories of quality of life, and .152 times higher number of carious permanent teeth. Among the symptoms of temporomandibular joint disorder, pain symptoms were 1.633 times higher in those who exercised flexibility (p<.05). Therefore, it is considered that flexibility exercise has value in that it has suggested a relationship not only with general health but also with oral health.

Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway

  • Lu, Mei-Li;Wang, Jing;Sun, Yang;Li, Cong;Sun, Tai-Ran;Hou, Xu-Wei;Wang, Hong-Xin
    • Journal of Ginseng Research
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    • v.45 no.6
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    • pp.683-694
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    • 2021
  • Background: Ginsenoside Rg1 (Rg1) has been well documented to be effective against various cardiovascular disease. The aim of this study is to evaluate the effect of Rg1 on mechanical stress-induced cardiac injury and its possible mechanism with a focus on the calcium sensing receptor (CaSR) signaling pathway. Methods: Mechanical stress was implemented on rats through abdominal aortic constriction (AAC) procedure and on cardiomyocytes and cardiac fibroblasts by mechanical stretching with Bioflex Collagen I plates. The effects of Rg1 on cell hypertrophy, fibrosis, cardiac function, [Ca2+]i, and the expression of CaSR and calcineurin (CaN) were assayed both on rat and cellular level. Results: Rg1 alleviated cardiac hypertrophy and fibrosis, and improved cardiac decompensation induced by AAC in rat myocardial tissue and cultured cardiomyocytes and cardiac fibroblasts. Importantly, Rg1 treatment inhibited CaSR expression and increase of [Ca2+]i, which similar to the CaSR inhibitor NPS2143. In addition, Rg1 treatment inhibited CaN and TGF-b1 pathways activation. Mechanistic analysis showed that the CaSR agonist GdCl3 could not further increase the [Ca2+]i and CaN pathway related protein expression induced by mechanical stretching in cultured cardiomyocytes. CsA, an inhibitor of CaN, inhibited cardiac hypertrophy, cardiac fibrosis, [Ca2+]i and CaN signaling but had no effect on CaSR expression. Conclusion: The activation of CaN pathway and the increase of [Ca2+]i mediated by CaSR are involved in cardiac hypertrophy and fibrosis, that may be the target of cardioprotection of Rg1 against myocardial injury.

The Effect of Social Support of the New-middle Aged Job Seekers on Life Satisfaction - Mediating Effect of Re-employment Desire (신중년 구직자의 사회적 지지가 삶의 만족도에 미치는 영향 - 재취업욕구의 매개효과)

  • Hwang, JooKyoung;Kang, SoonHie
    • Journal of Convergence for Information Technology
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    • v.11 no.7
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    • pp.145-154
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    • 2021
  • This study analyzed the relationship between the social support and life satisfaction of the new-middle aged job seekers, and the mediating effect of re-employment desire. Firstly, the relationship between social support and life satisfaction were significant, therefore it confirmed social support should be expanded to improve new-middle aged life satisfaction. Secondly, the desire for social status, self-realization and leisure utilization were significantly influenced in the relationship between the desire for re-employment and life satisfaction. Thirdly, the re-employment desire had a partial mediating effect in the relationship between social support and life satisfaction. These results suggest that it is important to establish a social network for emotional support continuously after retirement, in addition to career planning for re-employment in the process of preparing for retirement, in order to increase the level of life satisfaction of the new-middle age.

A Study on the Differences in Class Satisfaction of Students Majoring in Beauty by Teaching Methods of Theory and Practice Subjects before and after COVID-19 (코로나19(COVID-19) 전·후 이론 및 실습 교과목의 교수방법에 따른 뷰티전공 학생들의 수업만족도 차이 연구)

  • Kim, Jong-Ran
    • Journal of Convergence for Information Technology
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    • v.11 no.7
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    • pp.253-263
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    • 2021
  • This study aims to present effective teaching and learning methods for improving class satisfaction and improving the quality of university education by empirically analyzing changes in class satisfaction according to teaching methods such as face-to-face(FTF) classes, non-face-to-face(NFTF) classes, and blended classes of theories and practical subjects before and after COVID-19, targeting beauty major students who have a relatively higher proportion of practical classes than theoretical classes. For data analysis, SPSS 18.0 statistical package was used, and in the analysis of the difference in satisfaction with teaching methods for theoretical subjects before and after COVID-19, 10 items out of 20 items showed statistically significant differences, and 8 items out of 20 items in the practical subjects showed statistically significant differences. It is expected that the quality of university education will be improved by applying efficient and practical teaching methods considering the items affecting the class satisfaction according to the teaching and learning methods of these theories and practical subjects.

Reduction of Source/Drain Series Resistance in Fin Channel MOSFETs Using Selective Oxidation Technique (선택적 산화 방식을 이용한 핀 채널 MOSFET의 소스/드레인 저항 감소 기법)

  • Cho, Young-Kyun
    • Journal of Convergence for Information Technology
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    • v.11 no.7
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    • pp.104-110
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    • 2021
  • A novel selective oxidation process has been developed for low source/drain (S/D) series resistance of the fin channel metal oxide semiconductor field effect transistor (MOSFET). Using this technique, the selective oxidation fin-channel MOSFET (SoxFET) has the gate-all-around structure and gradually enhanced S/D extension regions. The SoxFET demonstrated over 70% reduction in S/D series resistance compared to the control device. Moreover, it was found that the SoxFET behaved better in performance, not only a higher drive current but also higher transconductances with suppressing subthreshold swing and drain induced barrier lowering (DIBL) characteristics, than the control device. The saturation current, threshold voltage, peak linear transconductance, peak saturation transconductance, subthreshold swing, and DIBL for the fabricated SoxFET are 305 ㎂/㎛, 0.33 V, 13.5 𝜇S, 76.4 𝜇S, 78 mV/dec, and 62 mV/V, respectively.

Convergence Study on Effects of Passive Stretching on Blood Fatigue and VAS after Delayed Onset Muscle Soreness (지연성근육통 유발 후 수동적 스트레칭이 혈중피로물질 및 VAS에 미치는 융합연구)

  • Kim, Jong-Hyuck;Kim, Do-Jin
    • Journal of Convergence for Information Technology
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    • v.8 no.6
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    • pp.93-99
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    • 2018
  • The purpose of this study was to prove the effect of passive stretching after delayed muscular pain induction in university students and to propose a rehabilitation exercise program for effective pain relief and prevention in case of injury. Subjects were divided into passive stretching group and control group. Passive stretching group was performed passive stretching after delayed muscular pain induction and control group did not perform any treatment after delayed muscular pain induction. The delayed muscular pain induction method was induced by bench step motion. The height of the step box was 50cm. The data were analyzed by two-way RGRM ANOVA for comparison of passive stretching group and control group. In conclusion, passive stretching after delayed myalgia has a positive effect on blood fatigue (CRP, LDH) and subjective pain scale(VAS).

Development of Automatic Drawing Program for Elevator Installation Drawing to Strengthen Competitiveness of The Elevator Industry (승강기 산업의 영업설계 경쟁력 강화를 위한 승강기 설치도면 자동생성 프로그램 개발)

  • Ko, Young-joon;Kim, Byoung-ik;Han, Kwan-hee
    • Journal of Convergence for Information Technology
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    • v.9 no.2
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    • pp.172-179
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    • 2019
  • Recently, design automation of installation drawings and design elements has been required in the elevator industry. This is recognized as an important role in securing adaptability on site, reducing design errors, and enhancing export competitiveness. However, in case of a small company doesn't have enough resources to develop the program, and it is difficult to develop a design automation program. Therefore, it is necessary to have an automatic drawing generation program that enables small companies to easily invest and use, while allowing users to concentrate on productive tasks. In this paper, we propose an automatic drawing generation program using parametric coding technique. This program is linked with the web service and automatically creates the drawing when the user enters the site information on the web. This is useful for elevator installation and maintenance due to reduced drawing time for elevator drawings.

Core Competence Evaluation Model of Play Worker Based on Delphi Technique (델파이 조사를 통한 놀이 전문가 핵심역량 분석)

  • Park, Hye-Jin;Kim, Yong-Young
    • Journal of Convergence for Information Technology
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    • v.9 no.2
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    • pp.100-107
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    • 2019
  • The purpose of this study is to develop an evaluation model to measure the core competences of actual play workers by exploring what competences are necessary for them to provide quality play. Based on literature review, we selected five core competences : knowledge of play, program development, understanding play culture, creativity, and information sharing & applying. In order to achieve the research purpose end, a two-round Delphi survey was conducted on 10 play and education experts. The findings drew scholarly consensus on the competences of play workers to have and proposed basic data by developing competences evaluation model to measure them. Each of the key competences has three sub-conpetences, each of which included two behavior elements. Furthermore, this study presented future research directions so that play can be voluntarily planned and supported in a social and cultural context.

High-speed visible light communication system using space division processing (공간 분할 처리를 이용한 고속 가시광통신 시스템)

  • Park, Jun Hyung;Lee, Kyu Jin
    • Journal of Convergence for Information Technology
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    • v.8 no.6
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    • pp.237-242
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    • 2018
  • There are various 'wireless communication technologies' around us. Wireless mobile communication has evolved through various stages, and its utilization is also diverse. However, due to the development of wireless communication technology, the demand for frequency resources is much higher than the supply, so frequency shortage is serious. Recently, 'visible light communication' has been attracting attention as an emerging communication technology that can solve the frequency shortage. 'Visible light communication' is a communication method based on serial data transmission / reception, and there is a difficulty in transmitting / receiving parallel data because the transmitter and the receiver are arbitrarily present. In this paper, we have studied parallel data processing of visible light communication. We could solve the problem by analyzing parallel data using image processing. Through this study, communication performance can be verified through I / O data comparison by implementing parallel data analysis method. It is expected that diversity in parallel data analysis will be presented through the results.