Objectives : The aim of this study was to introduce the development process of Korean medicine health aging program for the older that is suitable for applied at public health center. Methods : For the development of the draft of health promotion program, we conducted a literature review of previous studies through searching international and domestic databases. The opinions of several experts were also colleted. Results : The details of 8-week of Korean medicine healthy aging program are as follows: 8-week of taking herbal medicines (Yukmijihwang-tang or Palmijihwang-tang, or Jaeumganghwa-tang) based on counseling with Korean medicine doctor, qigong, acupuncture on head, abdominal hotpack, taking nuts, and health education Conclusions : This healthy aging program can help to develop the healthy lifestyle habits and increase the general health status of community seniors.

Objectives : Sojadodamgangki-tang and its main components are traditional korean medicinal methods for treatment of cough, sputum and dyspnea. Using a respiratory inflammatory model, we intend to reveal the anti-inflammatory effect and its immune mechanism of Sojadodamgangki-tang. Methods : We used a papain-induced respiratory inflammatory mouse model. 8-week-old female BALB/C mice were divided into 3 groups as follows: the following groups: saline control group, papain treated group (vehicle), papain and Sojadodamgangki-tang(200 mg/kg) treated group (n=4). To evaluate the anti-inflammatory effect of Sojadodamgangki-tang extracts, inflammatory cell infiltration was measured in bronchoalveolar lavage fluid (BALF) and nasal lavage fluid (NALF). In addition, the effects of Sojadodamgangki-tang extracts on Th2 cell population in lung were determined by using flow cytometry. Results : Sojadodamgangki-tang extracts administration reduced inflammatory cell infiltration in BALF and NALF, especially of eosinophils. Furthermore, total immunogloblin (Ig)-E levels was reduced in BALF and serum by drug administration. Interestingly, Sojadodamgangki-tang extracts treatment also decreased the Th2 cell (CD4⁺GATA3⁺) population in lung. Conclusions : Our findings indicate Sojadodamgangki-tang extracts have anti-inflammatory effects by mediating Th2 cell and B cell activation.

Objective : We studied prognostic biomarkers discovery for lung cancer based on the pattern identification for the personalized Korean medicine. Methods : Using 30 tissue samples, we performed a whole exome sequencing to examine the genetic differences among three groups. Results : The exome sequencing identified among 23,490 SNPs germline variants, 12 variants showed significant frequency differences between Xu and Stasis groups (P<0.0005). As similar, 18 and 10 variants were identified in analysis for Xu vs. Gentleness group and Stasis vs. Gentleness group, respectively (P<0.001). Our exome sequencing also found 8,792 lung cancer specific variants and among the groups identified 6, 34, and 12 variants which showed significant allele frequency differences in the comparison groups; Xu vs. Stasis, Xu vs. Gentleness group, and Stasis vs. Gentleness group. As a result of PCA analysis, in germline data set, Xu group was divided from other groups. Analysis using somatic variants also showed similar result. And in gene ontology analysis using pattern identification variants, we found genes like as FUT3, MYCBPAP, and ST5 were related to tumorigenicity, and tumor metastasis in comparison between Xu and Stasis. Other significant SNPs for two were responsible for eye morphogenesis and olfactory receptor activity. Classification of somatic pattern identification variants showed close relationship in multicellular organism reproduction, anion-anion antiporter activity, and GTPase regulator activity. Conclusions : Taken together, our study identified 40 variants in 29 genes in association with germline difference of pattern identification groups and 52 variants in 47 genes in somatic cancer tissues.

Objectives : This study aimed to identify the factors that affect the utilization of Korean Medicine within the past year. Methods : I analyzed micro-data from the Korean Medicine Utilization Survey (2020), which surveyed the general public. "User (in last 1 year)" were defined as those who had used Korean Medicine within the past year, while "Non-user (in last 1 year)" were defined as those who had used it in their lifetime but not within the past year. I examined several factors, including general characteristics, perceptions of Korean Medicine, satisfaction with Korean Medicine, and intention for future utilization. I conducted the Rao-Scott chi-squared test and complex sample logistic regression analysis. Results : I analyzed a total of 3,762 respondents, of which 1,442 (36.3%) were User (in last 1 year) and 2,320 (63.7%) were Non-user (in last 1 year). User (in last 1 year) and Non-user (in last 1 year) differed significantly in terms of demographic characteristics, perceptions, and satisfaction with Korean Medicine. Women, the elderly, those with low education levels, non-married individuals, those with low-income, chronic diseases, and poor subjective health conditions were significant factors. Those who used Korean Medicine within the past year were more knowledgeable about Korean Medicine than those who had not used it recently, and recognized herbal medicine as safer. In terms of satisfaction, User (in last 1 year) were more satisfied than Non-user (in last 1 year). The more women, the older, the more aware of Korean Medicine, the safer they perceived herbal medicine, the more satisfied they were with its use, the better their subjective health condition, and the absence of chronic diseases, the less they experienced Korean Medicine. Conclusions : The study showed that positive experiences and perceptions of Korean Medicine increase the likelihood of its utilization. Individuals with better subjective health conditions and without chronic diseases have a lower possibility of using Korean Medicine.

Objectives : This study aimed to investigate the recognition of coverage for Korean medicine treatments in private medical insurance among Korean medicine doctors (KMDs). Methods : Questionnaire reviewed by experts was performed to KMDs who were registered in the Association of Korean Medicine. The survey targeted awareness of private health insurance for Korean medicine, appropriate coverage, cost, and frequency. Results : Data were collected from 932 respondents out of 28,234 Korean medicine doctors. Most KMDs were aware of coverage for Korean medicine in private medical insurance, and they responded that pharmacopuncture and herbal decoction were covered first. KMDs also responded that the coverage should be provided without limited number of times, except herbal medicine. Conclusion : Most KMDs responded that Korean medical private medical insurance was essential. To promote the developing insurance for Korean medicine, survey for public and insurance company will be performed.

Objectives : We tried to propose the direction of Korean medicine education through the consideration of 'professionalism as a competency beyond knowledge-skill' that modern medicine should take and therefore the perspectives of the competency-based curriculum in Korean medicine education. Methods : Competency-based curriculum, professionalism education phase and competency at medical school, student demand survey, Korean medicine education Accreditation Standards, and related research articles were used. Results : Proposed development measures to cultivate students' professionalism in Korean medicine education are as follows. self-care and emotional stability programs, communications between patient and doctor and among the colleagues, career exploration programs based on global medical trends and government policy, standardized professional training programs, and the evaluation of teaching experiences and achievements. Conclusions : The main purpose of the reorganization of the competency-based curriculum should be for improving Korean medicine education. The contents of phase performance, process performance, and course performance should be carefully organized so that the core contents and spirit of traditional Korean medicine can be achieved. In modern medicine, education of professionalism has been used to cover the problems that arise from taking achievement goals only from a biomedical perspectives. Accordingly the education of professionalism is also important in Korean medicine education as the modern Korean medicine follows the aspect of modern medicine,

Objective : To investigate the usage of Korean herbal medicine (KHM) for climacteric symptoms, this study reviewed clinical studies conducted in Korea. Method : Literature search was performed on three Korean database; OASIS, RISS and NDSL. Studies published before July 2023 were categorized and analyzed according to the study type and herbal prescriptions. Results : Fifty-eight studies including 7 controlled trial, 27 case series and 24 single case reports were included in our review and the total number of case patients was 420. 52 prescriptions based on syndrome identifications and 11 prescriptions of Sasang constitutions were used and the most frequently used prescriptions were Soyosan(逍遙散) and Guibitang(歸脾湯). Thirty-two prescriptions were also mentioned in previous delphi research or clinical practice guideline, and the rest were not. Thirty-five studies used acupuncture combined with KHM and 10 studies used pharmacopuncture and 5 studies used herbal hipbath. Conclusion : To increase the therapeutic effect of KHM and establish KHM as an alternative to hormone treatment, various prescriptions should be used according to syndrome identifications in the clinical field. High-quality RCTs on frequently used prescriptions and the development of various type of KHM are also necessary.