Objectives : This is a study for technological forecasting, aiming to find out the promising future technologies in KM(Korean Medicine) and deduce implications for the research and development of KM. Methods : The first pool of 145 technological tasks related to KM were composed by reviewing the existing data related to technological forecasting. The steering committee for the research set 99 final technological tasks. With the deduced technological tasks, mini-Delphi(2-round) method was conducted and 6 research items were used-the importance, realization time, urgency, technological competitiveness, the main agent that will push forward the task, and obstacles. Results : As a result on the time when the technology will be realized, 58 out of 99 technologies(59%) were predicted to be realized in the same year domestically and globally. The average of the importance of the 99 technological tasks was 72.9. Among them. As for the main agent to push forward the research and development of future technologies, 'industry-academic cooperation' took the highest portion at 58.7%, and regarding the obstacles to realize technological tasks, the lack of infrastructure(research funds) was the highest at 33.6%. Conclusions : This study shows that the development of basic technologies in the technologies of Korean medicine is insufficient and it is believed that the development of basic technologies is urgent to promote the development of application technologies.

Objectives : We presented the results of reliability study in advance, and analyzed agreement between Korean medicine doctors(KMDs)' diagnosis and cold-heat pattern identification questionnaire(CHPI)'s diagnosis. Methods : This survey was conducted from May 16 to 17, 2015. The subjects were 93 adults living in rural society. Diagnosis of CHPI was performed by 2 KMDs who have clinical experience more than 5 years. The KMDs' diagnosis was set as a reference index, and then we compare 23 items(cold pattern 11 items and heat pattern 12 items) of CHPI questionnaire and 15 items(cold pattern 8 items and heat pattern 7 items) that were brief form of it. We had cut-off value by standard of KMDs' diagnosis using receiver operating characteristic-curve(ROC-curve), with which we calculated agreement including kappa value. Correlation analysis between CHPI evaluation score by KMDs and by the questionnaire was fulfilled as well. Results : Agreement about 11 and 8 cold pattern items showed 87.1% together, and the value of kappa each recorded 0.742 and 0.741. Agreement about 12 and 7 heat pattern items suggested 81.7% and 78.5%, and the value of kappa showed 0.634 and 0.570. Correlation coefficients were 0.803 of 11 items and 0.761 of 8 items about cold pattern. In addition, correlation coefficients were 0.789 of 12 items and 0.767 of 7 items about heat pattern. The significant probability (p-value) was under 0.001. Conclusions : We have developed CHPI questionnaire involving reliability and agreement based on usual symptoms, and hope additional complements so that Korean medicine diagnostics and Korean preventive medicine would be improved.

Backgrounds : Taiwan has similar national health insurance (NHI) system for traditional medicine with South Korea. Recently, new quality improvement policies for traditional medicine is being attempted in Taiwan. Objectives : This study aimed to review the Taiwanese NHI system for Chinese Medicine (CM) and introduce quality improvement policies. Methods : Research articles, reports, government publications and year books which handled traditional medicine system and NHI system in Taiwan were searched and collected. The authors analyzed and summarized the contents in a qualitative manner. Results : In Taiwanese NHI system, CM procedures and medication for outpatients are reimbursed through a mix of fee-for-service and global budget payment system. CM shares 4% of total expenditure of NHI in Taiwan. Mostly, the expenses for procedures are reimbursed regardless of disease type, however, in the specialized program for quality improvement, CM doctors have to comply with standard operating procedures (SOPs). Conclusions : Taiwanese NHI system implemented SOP-based new reimbursement system for CM. Yet, the scientific evidences for SOPs are not sufficient, it can be useful references when we develope disease related reimbursement system for Korean Medicine in South Korea.

Objectives : This study was to identify the stop-out experiences of Korean Medicine Students(K.M.S.). The stop-out is defined as a withdrawal temporarily from enrollment at a university. Methods : Data was collected through in-depth individual interviews from 2013 to 2016 and analyzed with Colaizzi's phenomenological methodology. The participants were interviewed once or twice, for 30minutes to 50minutes per interview. Results : Ten theme-clusters were identified from 21 themes. These theme-clusters were divided to 4 divisions as when they made the decision for the stop-out, during their stop-out period, when they went back to school and the meaning of their stop-out. 'A difficult situation to continue the study', 'Uncertainty about their decision and anxiety of the future' are 2 theme-clusters for when they made the decision for the stop-out, 'Conflict and anxiety', 'Novel and free time', 'Improving family relationship and finding new relationship' are 3 theme-clusters for during their stop-out period, 'Anxiety for the returning to school', 'New relationship and sense of relief' are 2 theme-clusters for when they went back to school, and 'Making a present for me', 'An opportunity for the emotional growth', 'Recovery of learning will' are 3 theme-clusters for the meaning of their stop-out that they gave to it. Conclusions : The stop - out of K.M.S. began at the hope that they want to take the lead for their lives. And they would find themselves more mature after the experience of their stop-out. This result could be a basic reference for the counselling of the faculty working with K.M.S.

Objectives : The aim of this study was to explore the academic failure experiences of Korean Medicine Students. The academic failure in a medical school is defined as the situation the student who have academic failure need to repeat their academic year again. Methods : Data were collected through in-depth individual interviews from April to May 2016 and analyzed through Colaizzi's phenomenological methodology. The participants were interviewed twice, for 30minutes to 60minutes per interview. Results : Eight theme-clusters of were identified from 21 themes. The theme-clusters were 'Dream of university life and freedom', 'Meeting Stranger academic field and growing study stress', 'Difficulty of self-management', 'Weak supporting system', 'Feeling of guilty, sense of isolation and decreasing in self-esteem', 'The experience during the vacation after the academic failure', 'The experience of returning to school' and 'Self growing through hard experience'. Conclusions : Understanding of academic failure experience of Korean Medicine Students is an important approach to counsel them and an important way to reach a good model of education at a medical college.

Objectives : The aim of this study is to introduce the Korean medicine respiratory management program in public health center and to analyze the effects of that program. Methods : The respiratory management program was targeted on 22 soldiers during March 2016. The interventions of this program were herbal medicines (Gilgyung-tang and so on), aromatherapy, peppermint tea, fine dust mask, and health education. Data were collected by retrospective reviewing medical chart and analyzed using SPSS 18.0. Results : Total symptoms scores were measured by 4-point likert scale. Total score was $5.50{\pm}4.848$ at 1st week and $3.27{\pm}3.058$ at 4th week (p=0.008). The severity of respiratory discomfort reduced by $-1.14{\pm}2.46$ compared with last year. The satisfaction score was $7.82{\pm}4.16$. The most hoping program was muscular skeletal disease management program. Conclusions : This study suggests that Korean medical world should prepare countermeasures to cope with diseases caused by air pollution.

Objectives : This study aims to investigate the current situation of domestic patents in Korea on natural products and to provide directions for developing and applying herbal medicinal products by in-depth analyses. Methods : Combinations of words, such as "A61K" or "A61P", "herb" or "Korean medicinal herb" or "Korean medicine" or "traditional" or "natural" or "$botanic^*$" or "China", and "medicine" or "treatment" or "prevention" or "improvement", were used to search patents in the World Intellectual Property Service (WIPS) database. Three methods were applied to analyze natural products patents. First, the number of patent registrations was sorted by year. Second, the assignees were analyzed by count and country of origin. Finally, cluster map analysis was conducted to explore frequently emerging words in natural products and the relationship amongst those words to treat corresponding diseases/technologies. Results : Results showed that, first, the total number of patents had been increasing. Among the patents, 76.4% were registered by domestic institutes/companies, and 23.6% by foreign institutes/companies. Second, USA, Japan, and China possess a considerable number of Korean patents and, therefore, domestic institutes/companies can seek joint technological development opportunities with their counterparts from those countries in the future. Finally, a total of four clusters were identified by cluster map analysis. Each of the clusters includes natural products related to diseases involving skin, aging, and blood sugar, as well as adult diseases. Conclusions : In this study, natural products patents registered in the Korean Intellectual Property Office were analyzed. The analyses results showed the kinds of natural products that had been employed for the treatment of certain diseases. However, natural products included in existing patents were minimal given that 4,174 species of indigenous plants are found in Korea. Thus, Korean institutes/companies should utilize unexplored plants to develop more value-added drugs.

Objectives : Traditional medicine(TM) of East Asia has been taking its status as part of complementary and alternative medicine(CAM) in the UK. However, the efficacy and safety issues make it hard to be accepted in the healthcare system. The aim of the research is to find out the current status of TM of East Asia in the UK and to discuss some issues around its acceptance as formal healthcare method. Methods : Articles, books and regulations related to the acceptance of TM of East Asia were analysed and the internet websites were visited such as Westlaw UK for legal materials, government websites for formal documents, and some UK-based associations. Keyword searches were followed and the essential parts from the articles and documents were generalised for the analysis and discussion. Results : Issues over TM of East Asia include identity as medicine, efficacy and safety, and the statutory regulation can be a measure for the acceptance. Osteopathy and chiropractic therapies came under statutory regulation among the CAM in the UK. Conclusions : TM of East Asia could be under the statutory regulation in the near future. Efficacy and safety issues are the challenging barrier. However, the approach from the viewpoint of TM of East Asia is necessary for development and good practice. The simplified registration procedure for traditional herbal medicinal product in EU can be the model. Education, evaluation, assessment and managing quality of practice are essential for the standard care and formal regulation.

Objectives : The effects of Jaeumkanghwatang (JEKHT) co-administration on the pharmacokinetics of tamoxifen were observed after oral combination treatment of tamoxifen 50 mg/kg with JEKHT 100 mg/kg on JEKHT 6-day repeated oral pretreated rats with 8-day repeated co-administration to confirm the effects of JEKHT co-administration on the pharmacokinetics of tamoxifen. Methods : Six days after pretreatment of JEKHT 100 mg/kg, tamoxifen 50 mg/kg was co-administered with JEKHT 100 mg/kg, once a day for 8 days within 5 min. The blood were collected at 30 min before administration, 30 min, 1, 2, 3, 4, 6, 8 and 24 hrs after end of first and last 8th tamoxifen treatment, and plasma concentrations of tamoxifen were analyzed using LC-MS/MS methods. PK parameters of tamoxifen ($T_{max}$, $C_{max}$, AUC, $t_{1/2}$ and $MRT_{inf}$) were analysis as compared with tamoxifen single administered. Results : Six-day repeated oral pretreatment of JEKHT and 8-day repeated oral co-administration of tamoxifen within 5 min did not influenced on the plasma concentrations and pharmacokinetic parameters of tamoxifen, oral bioavailability, as compared with tamoxifen single treated rats, except for some negligible effects. Conclusions : It is concluded that JEKHT did not influenced on the plasma concentrations and pharmacokinetic parameters, the oral bioavailability of tamoxifen. Therefore, it is considered that co-administration of JEKHT and tamoxifen will be provide an effective novel treatment regimen on the comprehensive and integrative medicine for breast cancer patients, if they showed favorable synergic effects on the pharmacodynamics or reduce the tamoxifen treatment related toxicity and side effects in future studies.