A commercial CFD code is applied to analyze the 3-D viscous flow field within vertical multi-stage centrifugal pump including impeller with 6 blades and guide vane with 11 blades and is performed by changing flow rate from 10 to $26m^3/h$ at the constant 3500rpm. The purpose of this 3-D numerical simulation is not only to confirm how much the effect of three kinds of blade inlet breadth (11mm, 11.5mm, 12mm) of impeller has influence on the performance of vertical multi-stage pump but also to make clear the cause about performance difference at the exit side of impeller and guide vane. The vertical multi-stage pump consisit of the impeller, guide, vane and cylinder. The grid of numerical analysis used to the vertical multi-stage pump is 18,000, 45,000, and 100000 cells in case of the impeller, guide vane, cylinder and total grid is 730,000 cells. The characteristics such as total pressure coefficient, total head, shaft horse power, power efficiency at the exit side of impeller and guide vane, discharge coefficient are represented according to flow rage changing.