This study is on the characteristics of LiSangSockDanBang(理傷續斷方). Through this study, the characteristics of LiSangSockDanBang(理傷續斷方) can be oganized as the following: First of all, in LiSangSockDanBang, the treatment of traumatic injury is consisted of the fourteen steps. This fourteen steps is resorted by four steps. ; Washing(洗藥法), Standin in line(整復法), Using an external application(外治法), Using an internal medicine(內服法). This is LiSangSockDanBang's major characteristics. Because of this contents, LiSangSockDanBang is quoted on EuiBangLyuChi(醫方類聚). The first treatment of traumatic injury is Wahing. Wahing is not only sterilizing a wounded region but pushing out the PungSa(風邪). So, to avoid a infection of a tetanus, washing medicine consist of the herbs, that push out the PungSa(風邪). LiSangSockDanBang has high level of surgery. In 1456, YoungLyuGumBang(永類鈐方), has no more level than surgery's in LiSangSockDanBang, is reprinted. This fact means that the surgery is used frequently in those days. In this scientific backing, an operation needle, that described in ChiJongJiNam(治腫指南) and ChiJongBiBang(治腫秘方), are written by Lim UnGook(任彦國), is used frequently, too. In LiSangSockDanBang, the major external applications are HookLyongSan(黑龍散) and PungLyuSan(風流散). In case of open wound, the HookLyongSan is used but in closed wound, PungLyuSan is used. The internal medicine has three applications. ; Removing extravasated blood(瘀血), Catharsis(通利大小便), Supplementation(補氣血).

Haedae(海帶, haidai) is representative herb from seaweeds, but its origin is still confusing. Thus we analyzed its origin on the basis of classics of oriental medicine. The scientific name of Haedae corresponds to Zostera marina, according to the folkloric use. But, it is Laminaria japonica, according to its habitat, morphological feature, and the korean name on the medical books in Joseon since 17c. In the remote past, it seemed that two groups were segragated by the name of Zostera marina Haedae and Laminaria japonica Haedae. However, it is thought that this two trends were mixed up when medical knowledge was compiled in Song Dynasty era. Documental support inclined to Laminaria japonica, but it is too early to conclude that Laminaria japonica is the Haedae. To prove this hypothesis, further study is required to investige whether Laminaria japonica or Zostera marina has mentioned efficacies of Haedae used for the treatment of wen, San syndromes, edema, scrofula, etc. And we have need of research that solve the origin problem of Gonpo(Laminariae thallus) on the assumption that Laminaria japonica is Haedae.

Most of studies on tobacco have researched it as economic or cultural factor. These studies, certainly, have the value of their own. But from time to time these studies have brought about romantic view regarding tobacco, and have been an obstacle to approach it as a medical factor. Thus this thesis will introduce documents of tobacco as medical factor. Through it we will be able to furnish researchers with information to treat poison caused by tobacco.

Narratives are the old stories handed down for a long time, which are not personal creations but common ones for ages. They were formed from the public consciousness, passed orally and recorded in letters. There have been lots of studies on narratives about characters, whereas there have been poor in the studies on the great doctors. The author examined the narratives about great doctors in literature for successive generations, and made researches on world view and consciousness of reality reflected on the age directly or indirectly. The author inquired into the descriptions and constructions of the narratives separately, and classified the great doctors in literature into the miraculous doctors, eccentric doctors and righteous doctors. Therefore truly great doctor is the one who treats not only personal diseases but also social problems, and who tries to harmonize with human beings and nature.

The history of medicine has a strong correlation to the ancient development of epidemics. Although the study of the history of East Asian Traditional Medicine does not put much emphasis in understanding the flow of medical history in relation to epidemics, it largely impacted the development of this epidemic and the compilation and evolution of treatment methods. The same was true for Korea as they linked development of epidemics, unusual natural conditions, and social phenomenons from ancient documents. This study methodically classifies the epidemics mentioned in ${\ulcorner}$三國史記${\lrcorner}$ and concludes on how ancient Koreans understood epidemics.

This Study is to propose the method about statistical factor from the old oriental medical record in Korea. This Study reviews the statistical analysis recently published in the old oriental medical books which are in the Research Report by the Korea Institute of Oriental Medicine at 2007. The results reveal a disease factors, prescription factors.medicines factors, population factors and historical factors by the statistics. The results show that the old oriental medical record for a information system need the interpreting with a information analysts, a statistics analysts and an oriental medical doctors.

Seoul Bochun Medical Clinic Examined Patient Table' is a statistical data that Kim Young-Boon [1882-1974] put together himself. A total of 59353 cases from 1914 to 1935 were classified according to year and month of examination, and gender. Of the cases 26497 (${\fallingdotseq}$45%) were women and the remaining 32856 (${\fallingdotseq}$55%) cases were men. The most frequent disease examined was cold, followed by diarrhea and stomachache. Of the 639 different kinds of diseases ever examined, 71 had occurred on more than 100 occasions. The percentage that these 71 diseases occupies is an overwhelming 88.75%.

King Se-Jong, who had put much effort into maintaining the national structure, published geological documents to reinforce his authority and through these documents could see the nationwide distribution of medicinal resources. Since then the regional geological documents published in each region included information on the local medical environment of those times. This study is one that focuses on how to specifically understand oriental medicine resources and the contents of ancient medicine by applying the appropriate geological information.

Objective : To investigate documented surveys about adverse events of acupuncture therapy. Methods: We searched Medline with the terms of 'acupuncture/adverse event(s)', 'acupuncture/side effect(s)' and 'CAM/adverse event(s)' using Pubmed and set the limits to human study. Results: There were 5 prospective studies, 3 reviews and 3 surveys in our searching. There were 3 reports about acupuncture related adverse events in UK ranging from 10.7% to 15% of which the rate of significant events were from 0.13% to 0.14%. In Germany, there were 11% of acupuncture related adverse events in one report and 7.5%(significant events were 45 in 190,924 patients) in another report. In Australia, one study reported that every adverse event associated with acupuncture occurred in 8-9 month per one practitioner. In Japan, 0.14% of acupuncture related adverse events in 48 practitioners were reported in one systemic review. A cumulative review about significant adverse events associated with acupuncture reported 715 adverse events of which most frequent accidents were pneumothorax and central nervous system injury. Conclusion : The risk of adverse event associated with acupuncture is far lower than that associated with other general medical interventions. However, some safety guidelines about the acupuncture performance are needed.

Objectives : The aim of this study was to investigate the antihypertensive effect of S'NC nerve control treatment in hypertensive patients. Methods: We measured the blood pressure of 5 patients who were admitted in the Oriental Medical Clinic of S'NC Medicine Research Institute from 19th April 2007 to 29th June 2007. Eligible participants had systolic blood pressure ${\ge}$140mmHg or diastolic blood pressure ${\ge}$90mmHg. Blood pressure measurements were after the patient had been in bed rest for at least 10 min. Ten sessions of S'NC nerve control treatment over 2 weeks were performed in the patients. Blood pressure were measured twice before and after each treatment. Results : After 2 weeks, blood pressure reduction was observed in the treatment patients, with an average decline of systolic blood pressure up to 21mmHg and diastolic blood pressure up to 20mmHg. But, there were not statiscally significant The effects of S'NC nerve control treatment by measuring time on blood pressure were as follows: In a systolic blood pressure(p=0.087) and diastolic blood pressure(p=0.609) was gradually deceased not significantly from 1st to 10th. Conclusion: These results suggest that S'NC nerve control treatment may be efficacious in decreasing arterial blood pressure in hypertensive patients. Controlled trials investigating the efficacy of S'NC nerve control treatment for lowering blood pressure are warranted.

The object of this study is to evaluate confounding effect of sleeping behavior on heart rate variability (HRV) in healthy volunteers during a randomized clinical trial. From 6 healthy volunteer, we acquired circadian electrocardiography(ECG) with a Holter monitoring device(DigiTrak Plus, Philips). The compatible analytical program, Zymed, was used for calculation of RR intervals of 24h ECG signal. Then, we generated HRV signals and calculated 9 HRV parameters in time domain and frequency domain for every 30 minute with Matlab 6.x software. We also encoded participants' activities as follows; stable condition(1), sleeping behavior(2), eating behavior(3), and undefined condition(4). Using SPSS 12.0, we tested if there was any difference between HRV parameters of day-time and night-time and between those of a subject in stable condition and in sleeping behavior. As a result, one of the most important parameter-LF/HF ratio, which indicates the autonomic balance between sympathetic and parasympathetic nervous systems, as same the other parameters, showed large inter-individual variations in circadian profiles. And, the mean LF/HF ratio of each participant was different between in stable condition and in sleeping behavior (p<.05). Consequently, the effect of sleeping behavior must be considered when one or more of HRV parameters, especially LF/HF ratio, are used as assessment index in clinical studies.

This work reports the pulse diagnosis system using FBG sensors which can display pulse signals detected while oriental medical doctors are conducting pulse diagnoses and simultaneously pressing the sensors by three fingers. Each optical fiber has five FBG sensing units fabricated in 2 mm width and 2 mm inter-sensor spacing. Three optical fibers with the FBG units in the parallel line configuration are then placed on each finger-pressing region and thus overall 9 fibers are used for the pulse measurements on the so-called "chon", "gwan", and "ch대k". A fixture holding the optical fiber arrays is able to adjust the height of the FBG sensing units while placing the fibers on the wrist. The pulse signals detected by the FBG sensors from chon, kwan, and chuk have been analyzed using 4 channel spectrum analyzer connected to the optical fibers. The measured pulse signals exhibit variations due to the nonuniform pressure distributions applied. resulting in the differences in the detected pulse signals between fiber lines. However. this work is the first step towards objective and quantitative analyses of the pulse diagnosis in oriental medicine which has traditionally been performed on subjective basis. Future works will be devoted to improving sensor stability, developing the way applying pressure and algorithms reporting the objective classification of the pulse status from systemic measurements using the sensors instead of relying on the clinicians' diagnoses subjectively performed. A successful pulse diagnosis system emerging in the future is expected to contribute to education as well as promoting pulse diagnosis in oriental medicine to the scientific research area.

The study aims to measure and analyze the thickness and depth of blood vessel on the pulse diagnosis locations and the blood velocity through the use of ultrasonic waves (LOGIQ5PRO, GE Medical, U.S.) in order to understand the structural difference of pulse diagnosis locations. The subjects included 44 healthy men and women(22.28${\pm}$2.62 age) considered normal in terms of Body Mass Index(BMI). The thickness and depth of the blood vessel and the blood velocity were measured three times on CHON, KWAN and CHUCK to obtain the average value. Results showed there is a statistically significant difference among the variables measured on CHON, KWAN and CHUCK. A difference according to gender was also observed. This explains why an oriental medical doctor can tell the difference in pulses depending on the location of CHON, KWAN and CHUCK. In addition, the difference in pressure between CHON and KWAN was higher than that in pressure between KWAN and CHUCK. The findings explain why oriental medical doctors take pulses by dividing CHON, KWAN and CHUCK in the short length of the three fingers. It can be used to develop a pulse diagnosis device enabling accurate measurement according to the characteristics of blood vessel structure based on where the pulse is taken. Furthermore, the results can be used as basic data for the development of a pulse diagnosis simulator.

Introduction: In Oriental medicine, the status of tongue is the important indicator to diagnose one's health, because it represents physiological and clinicopathological changes of inner parts of the body. The method of tongue diagnosis is not only convenient but also non-invasive, so tongue diagnosis is most widely used in Oriental medicine. By the way, since tongue diagnosis is affected by examination circumstances a lot, its performance depends on a light source, degrees of an angle, a medical doctor's condition etc. Therefore, it is not easy to make an objective and standardized tongue diagnosis. In order to solve this problem, in this study, we tried to design a discriminant function for thick and thin coating with color vectors of preprocessed image. Method: 52 subjects, who were diagnosed as white-coated tongue, were involved. Among them, 45 subjects diagnosed as thin coating and 7 subjects diagnosed as thick coating by oriental medical doctors, and then their tongue images were obtained from a digital tongue diagnosis system. Using those acquired tongue images, we implemented two steps: Preprocessing and image analyzing. The preprocessing part of this method includes histogram equalization and histogram stretching at each color component, especially, intensity and saturation. It makes the difference between tongue substance and tongue coating was more visible, so that we can separate tongue coating easily. Next part, we analyzed the characteristic of color values and found the threshold to divide tongue area into coating area. Then, from tongue coating image, it is possible to extract the variables that were important to classify thick and thin coating. Result : By statistical analysis, two significant vectors, associated with G, were found, which were able to describe the difference between thick and thin coating very well. Using these two variables, we designed the discriminant function for coating classification and examined its performance. As a result, the overall accuracy of thick and thin coating classification was 92.3%. Discussion : From the result, we can expect that the discriminant function is applicable to other coatings in a similar way. Also, it can be used to make an objective and standardized diagnosis.

Objectives: We intended to know sensitivity, specificity and relation of diagnosis methods of Sasang Constitution. Methods: We compared QSCC II, PSSC, Body measurement dignosis results with gold standard ones which were diagnosed by Sasang Constitution specialist, and analyzed by crosstables to get the sensitivity and specificity of those. Results and conclusions 1. Sensitivity and specificity of one diagnosis method were low, so call, in QSCC II, Taeumin is 49% in sensitivity, 97% in specificity, Soeumin is 67%, 69%, Soyangin is 59%, 75%, in Body measurement, Taeumin is 66%, 89%, Soeumin is 70%, 82%, Soyangin is 49%, 78%. in PSSC, Taeumin is 57%, 90%, Soeumin is 88%, 62%, Soyangin is 18%, 88%. 2. When two diagnosis methods are consistent each other, sensitivity and specificity are more higher than one diagnosis method. 3. When three diagnosis methods are all consistent, sensitivity and specificity are most highest, but in Soyangin, those are decreased comparing with the case of consistency between QSCC II and Body measurement.

Objectives: We intended to know the total health state and suggest basic result for good health management of oriental medical university student by examining Sasang constitution and health degree(THI: Todai Health Index). Methods: We diagnosed Sasang constitution using QSCC II and also estimated health degree using THI. We recruited the student of 9 universities and analyzed. Results 1. The score of psychiatric health was higher than physical one. 2. Degree of health state of Soeumin was worse than Taeumin in category of Digestive(p=0.015) and Irregular life (p=0.002) and worse than Taeumin and Soyangin in Nervousness(p=0.000), Mental Irritability(p=0.000) and Depression(p=0.007). 3. Soyangin was worse than Soeumin and Taeumin in Fiction(p=0.000). 4. Aggressiveness showed a tendence of increase in order Taeumin, Soyangin, and Soeumin. Conclusions : The oriental medical student of university needed health management focusing on psychiatric health aspect rather than physical one. And there exist the difference of health problem according to Sasang constitution. So the student should have deal with health management efficiently according to that.

Objectives : This study aimed to evaluate present status and future of traditional medical service market, focusing on the Korean medical center. Methods: We chose the subject with simple random sampling and investigated through interview and internet with questionnaire. Total 319 people helped us. Results: 1. It was investigated that, the number of the Korean medical centers which was operating traditional medical service was 9,910. And the number of people in the business of traditional medical service was estimated by total 46,577 in 2005. 2. Average sales of Korean medical center in 2003 was 24.8 million won. increased by 25.6million won in 2004, 28.3million won in 2005. 3. At the end of 2005, the scale of traditional medical service market was estimated by 2 trillion 7,676 hundred million won. Conclusions : Korean traditional medical service industry has been developed and will be developing by 2.8 times in 2015.

Sagunja-tang(Sijunzi-tang) has been traditionally prescribed as a restorative. The present study was undertaken to determine the possible toxic effects of Sagunja-tang on SD rats. In this study, we investigated the subacute toxicity of water-extracted Sagunja-tang(Sijunzi-tang) on SD rats. Twenty rats were orally adiministered Sagunja-tang for 28 days at a dose of 0 mg/kg(control group) or 1500mg/kg(treated group), respectively. All of subjects was survived. No significant difference in abnormal clinical signs, related to hematological values, serum biochemical values, water and feed intake, coagulation time, autopsy analysis, organ weight, tissue microscopically, funduscopy, urine intake and urinalysis, was detected. Compared with the control group, we could not find any subacute toxic alteration in treated group (1500mg/kg) for 28 days. This result suggests that Sagunja-tang(Sijunzi-tang). a herbal medicine prescription, is a safe prescription to body.

Objective: Polygonum multiflorum Thunberg (Polygonaceae) has been traditionally used as a tonic and the purgative in China and Korea. The genus Polygonum is a source of a wide range of phenolic compound, flavanoids, anthraquinones, stilbenes and tannins. In this study, three anthraquinones were isolated and quantitative determination of anthraquinones from P multiflorum has been developed for quality standardization. Methods : Three anthraquinone derivatives were isolated from a methanol extract of the radix of P. multiflorum by the chromatographic separation. Their structures were identified as emodin, physcion and ${\omega}$-hydroxyemodin on the basis of spectral data (MS, lH-NMR, 13C-NMR) and chemical analysis. HPLC analysis was performed to determine the contents of emodin, physcion, chrysophanol, rhein and ${\omega}$-hydroxyemodin in P. multiflorum from different specimens were collected from twenty Korean markets. Results: According to the results, the contents of emodin, physcion, chrysophanol, rhein and ${\omega}$-hydroxyemodin were 0.145%, 0.434%, 0.016%, 0.026%, 0.030% by HPLC, respectively. Conclusions : In these results, we have determined the contents of emodin, physcion, chrysophanol, rhein and ${\omega}$-hydroxyemodin in P. multiflorum, respectively. We hope that this study will contribute to the standardization and quality control of herbal medicine.

This article explores how non-dominant medical practitioners shape their own self-images and the identity of relevant medicine and in what ways fashioning of self-images and accompanying modalities of medical practice informs the social evolution of the medicines at specific times and over specific places, by means of the historical configuration of osteopathy and chiropractic in the UK and the US. Attention is directed onto motivations and pursuits for professional recognition and actual strategies and activities of non-dominant medicines and its practitioners by turning to historical instances such as osteopathy and chiropractic in the UK and the US, not least drawing focus on professional desires with regard to circumstances it faces within and without. Some non-dominant medicines as a way with which to acquire and protect the exclusive monopoly of its knowledge and practical skills, adopted various forms of professionalism project, as dominant biomedical groups pressed up non-dominant medicines by virtue of marginalizing tactics. Meanwhile, non-dominant medicines took somewhat distinctive professionalisation strategies from each other. Strategies they took were diversified depending on medical philosophy, healing modality, the degree of occupational solidarity embodied as forms of medical organisation, and especially vocational aspiration and prospect. Change of socio-medical culture and the state's policy seems to have wielded critical influenceon the determination of the ups and downs of non-dominant medicines. From the perspective of long-term time span, dominant biomedicine eventually did not have much influence on the ups and downs of marginalized medicines in so far as in the case of osteopathy and chiropractic in Englandand the U. S.

Yifangleiju is a collection of medical books that consists of 266 volumes. It is a very important set of data in studying ancient Asian medicine because it systematically organized the many medicine-related data of Eastern Asia. But it was never published again after its 30th volume was published in 1477, and only a single copy remains in Japan today. Because this book is valuable it has been republished in China based on the copy in Japan. This study is a study of the many problems that occurred in the process of republishing Yifangleiju in China.

As adjacent nations, China and Chosun was a part of the same cultural area and exchanged information on many different fields. The same was true for the medical field as well. Medical books published in China were republished in Korea and vice versa. While doing so the two nations greatly influenced each other's medical fields. The following study is a result of researching the medical books published in Chosun and analyzing how they influenced Chinese Traditional Medicine.