Objective : The objective of this study is to verify the characteristics of acupuncture methods of Joseon Dynasty by looking into the relationship between five viscera diagnosis and acupuncture methods. Material & Method : In the process, I've reviewed the relationship between meridian/exterior and viscera/bowels, along with a thorough comparison of the academic tendency in acupuncture of Ming-China, Qing-China and Joseon. Result & Conclusion : The two fields of meridian and exterior, and viscera and bowels had been theoretically merged, and based upon that, foundation methods applying the five viscera diagnosis were designed. Joseon acupuncture exceeded the existing concept of viscera which simply related itself to the exterior meridian and exterior by integrating the concepts from the visceral manifestation theory. With this, large proportions of medicine related to the visceral manifestation theory were invited into acupuncture, expanding therapeutic boundaries for acupuncture treatment. A historical review on medical texts starts from the Hyangyakjipseongbang("鄕藥集成方") which familiarized the public with mainstream acupuncture knowledge up until the Song dynasty, followed by Uibangyuchwi("醫方類聚"), which sparked up interest on the acupuncture methods based on viscera and bowels. Donguibogam("東醫寶鑑") organized the medical theories up until then, building a foundation upon which viscera/bowel-based acupuncture was able to develop further. In Chimgugyeongheombang("鍼灸經驗方"), viscera/bowel-based acupuncture methods started to blossom, integrating the meridian and exterior theory with the viscera manifestation theory, which in turn provided various methods through five viscera diagnosis. In the Saamdoin acupuncture method(舍岩道人鍼法), diagnostic criteria moved on to the five viscera diagnosis, and new methods resulting from the inter-complimentary and inter-prohibiting relationships between the five phases were introduced, opening a new world of acupuncture.

Patterns are symbolic expressions of life style or sentiment of people as a product of culture. Furthermore, it is a type of language that the shape or implication does not change much over time. Patterns shown on the Korean medical containers are related to human life and health that they are not very diverse and splendid but closed used in real life. The medical containers include the alcohol container or tea-ware in broad sense, but under this study, it would be handled only for the Korean medical containers directly used to protect human health and treatment of diseases. They would be the Medicine Mortar and Pestle that is used to grind the herbal medical ingredients, pots that hold the liquid decoction, containers to keep the medical ingredients in general conceptual use for medical purposes. The patterns inscribed are classified in animal pattern, plant pattern or alphabet pattern. Turtle, crane, ginseng, and life patterns have the contemplation to pray for long life without disease or good fortune, while plum pattern, dragon pattern and the like are used in the medical containers used mainly in royal families with the social status and dignity shown. As such, patterns have not only ornament elements but also the symbolic implication to represent long life without illness for human. It provides the basic data of medical wisdom contained in the pattern and willingness of human to protect life from illness. On the basis of such research, it would require ensuing studies to make comparison and analysis with the medical containers with the patterns in the adjacent countries in the days to come.

Objective : There is a growing interest on Complementary and Alternative Medicine(CAM). But the term 'CAM' often causes confusion, for the perception of CAM is determined by how the relationship between CAM and Conventional Medicine is established. Methods : In this paper, we researched the concept of CAM through the change in the terminology and definition of CAM throughout history. Furthermore, we also analyzed related papers in Korea. Results : International studies show that the relationship between Conventional Medicine and CAM has become more cooperative. Meanwhile, in Korea, Korean Medicine is categorized as a type of Conventional Medicine, not CAM. Conclusion : Though Korean Medicine is included in Conventional Medicine in Korea, the research methodology is still restricted in ways of bio-medical science. Further study on the original research method of Korean Medicine is needed.

Background : Meditation is one of the healing therapies used to prevent and cure ailments and to improve health through regular practice. Although Meditation is within the paradigm of modern Western medical science, effects on the human body could be possible. Objectives : This study performed a systematic review of the literature published in Korea focused on mindfulness meditation (MM), which is being applied as mind-body therapy around the USA lately. Method : Three hundred sixty six articles were found after searching with keyword, 'mindfulness meditation (MM)' in 6 journals and web databases. Ninety papers related MM were analyzed trend, Seventeen randomized controlled trials (RCTs) and 38 controlled clinical trials (CCTs) were researched by systematic review. Result : Most of them were studies about relationship between MM and syndrome such as stress, depression, anxiety and MM was also applied to some disease like hypertension, temporomandibular joint disorder in some cases. In 55 studies, It was shown that MM has positive effects on various symptoms and sometimes the effect of MM showed at post and follow-up study although there was no significant difference between control group and experimental group in some cases according to outcome measurement. Interestingly, there was no study reported about side effects of MM after the application. Conclusions : MM is being clinically applied at both western and oriental hospital in Korea, but more clinical trials with the high quality are needed to support its scientific basis.

This study is to discuss the content of Posangkimun on the whole and to report the understanding of Seokgok Lee Gyujoon on western civilization. Through the overall analysis of Posangkimun, it is found the following facts: 1. Posangkimun aroused interest of academic circles as it covered theories of western civilization. Most of the introduction to western civilization contained in the book is related to astronomy and geography. Seokgok criticized all the western theories on revolution of the earth, astronomy, continents and oceans on the ground that these theories were not congruous with the teaching of the Oriental sages. 2. Seokgok found the reasons why the West had led the East from 'nationalism' of the West. The nationalism mentioned here were more similar to 'democracy' in modern sense, or rather 'democratism'. What is specially noteworthy is that he did not find the reasons of western advancement from the spiritual issues not from the machine civilization. In this way, Seokgok could avoid the fallacy of throwing away traditional ideas to concentrate in western machine civilization. 3. The content of Posangkimun shows that Seokgok was a person with a very conservative view. Notwithstanding his inclination, he had good knowledge about western theories, most of which were gathered from newspapers and magazines at that time. It means that newspapers and magazines should be treated with more importance when studying Korean intellectuals in late Joseon period or during the time of Japanese forced occupation.

Objective : This study aims to clearly define the concept of Korean medicine terminology related with breast disease that occurs during breastfeeding. It attempts to suggest aguideline so that identical terms can be used to explain the medical conditions of breast-feeders from the perspective of oriental medicine. Method : This paper is based on what is recorded in medical books. It has organized the relations between the terms grounded on the analysis of similarities and differences in the concepts of the terms contained in them. The medical book chiefly used here was "Uibangyuchwi(醫方類聚)". To organize the terms, thesaurus was utilized. Result & Conclusion : The terminology of Korean medicine related with breast disease that occurs during breastfeeding is prescribed from the aspects of the causes, affected areas, or pathological conditions. The clinically typical terms of korean medicine are 'Tuyu(妬乳)' and 'Yuong(乳癰)'. The two are distinguished by whether one has systemic symptoms or not. If one has no systemic symptom, it is 'Chwiyu(吹乳)' or 'Tuyu', and these two are distinguished by whether one has 'Chang(瘡; sores)' or not. It is significant to organize the concepts of korean medicine terminology since they are directly related with treatments in the field.

Objective : The purpose of this study was to provide the information about Bojungikki-tang by domestic papers and theses. Method : Domestic papers related to Bojungikki-tang were reviewed and analyzed. These papers were classified by year, research method, experimental method, and subject. Result : The following results were obtained in this study. 1. The study of Bojungikki-tang started from 1984 and continued steadily. 2. The domestic papers about Bojungikki-tang were 47 volumes. Among them, there were 26 volumes since 2000. 3. Classified by research method from the year 2000, 20 experimental studies, 4 clinical experiments, and 2 documentary researches. 4. Classified by experimental method from the year 2000, 10 studies used mouse in vivo experiment and 4 studies used rat in vivo experiment and 6 studies used each cell in vitro experiment. 5. Classified by subject from the year 2000, papers related to immune enhancing effect, nerve and mental system, radiation protection effect, anti-allergy, anti-inflammatory, anti-cancer, remedy of diabetes, skin protection and so on. Conclusion : Many papers of experimental studies, clinical experiments and documentary researches related Bojungikki-tang are included in domestic journals. Bojungikki-tang is being researched variously in immune enhancing effect, nerve and mental system, radiation protection effect, anti-allergy, anti-inflammatory, anti-cancer, remedy of diabetes, skin protection and so on. However, more clinical studies on Bojungikki-tang are needed.

In this paper, we designed and implemented a semantic social network system in Korea Institute of Oriental Medicine (abbreviated as KIOM). Our social network system provides the capabilities such as tracking search, ontology reasoning, ontology graph view, and personal information input, update and management. Tracking search provides the search results by the research information of relevant researchers using ontology, in addition to those by keywords. Ontology reasoning provides the reasoning for experts, mentors, and personal contacts. Users can easily browse the personal connections among researchers by traversing the ontology by graph viewer. These allows KIOM researchers to search other researchers who could aid the researches and to easily share their research information.

Objectives : Recently, in Sasang Constitution Medicine (SCM), many researchers have studied to construct objective diagnose tool for the SCM type. It is most important to collect correct constitutional clinical data in these studies. Methods : In our work, we construct a web-based system for collecting constitutional clinical data effectively. Results & Conclusion : The system offers 4 types of input programs, which helps to collect clinical information from various hospitals, and performs verification service to minimize input errors. Currently, we have collected about four thousands data using the our system and we will provide several analysis tool in the system for researchers.

Traditional Korean Medicine Information Portal OASIS has been upgraded continuously from the beginning of it's service. It builds up more contents and adds more functions to provide rich information for TKM's researcher. But it's improvement strategy is not systematic and not supported from objective data. So we did online survey and analyzed the results to get insight for improving and activating the OASIS. Also we compared the survey with the previous one conducted in 2009. From the analysis of survey, we can get the 4 results. First OASIS have aged users than young users. Second 39.0% users are using OASIS 2-3 times in a month. Third 18.8% users want OASIS to provide the conference paper in TKM. Finally 21.7% users want paper map analysis system. We must do information strategy planning to get the insight for the improvement. And this survey analysis result will be most important material to our planning. Also we will use this survey analysis result to satisfy the users' needs.

Cervical disc herniations can press on the spinal cord and cause a problem called cervical myelopathy. The most common symptom of cervical disc herniation is neck pain that spreads down to the upper limb in various locations. There can also be associated with weakness and movement disorders of upper limb. In Oriental medicine, cervical disc herniation is treated with herb-med, physical therapy, acupuncture, Chuna, etc, but the Bee Venom therapy is the most common and effective. In this case, we used the Bee Venom therapy at cervical hyeopcheokhyeol for about 2 months to a patient who was diagnosed with disc herniation at Cervical 5-6, 6-7 and appealed weakness, limited elevation and abduction of the left upper limb. As a result, left upper limb disability was improved. Using the Bee Venom therapy at cervical hyeopcheokhyeol that are effective on movement disorders and neurological diseases of upper limb is an effective treatment to upper limb disability diagnosed with cervical disc herniation, and suggests the direction of the treatment to upper limb weakness and movement disorders diagnosed with cervical disc herniation.

Objectives : The bone proportional cun and body cun have been used widely for the location of acupoints in oriental medical clinic. The aim of this study is to compare the two location methods. Methods : 21 students were examined for the location of 6 acupoints (each 2 points in the 3 parts of upper limb, abdomen, and lower limb) using the twe methods. The data of location were analyzed with t-test. Results : In the upper limb, the data from bone proportional cun and body cun were proved to be different significantly. However, there was no significant difference between the data from the two methods in the abdomen and lower limb. Conclusion : The results of this study demonstrate that the oriental medical doctors should be more careful in the choice of appropriate method for the location of acupoints in the upper limb, while it is not important whether they use bone proportional cun and body cun in the abdomen and lower limb.

Objective : Benign prostatic hyperplasia(BPH) is one of the most common diseased among elderly men. BPH can be treated with alpha-1 adrenergic blocker or $5{\alpha}$-reductase inhibitor(Finasteride) that reduces serum dihydrotestosterone(DHT). Phellodendri Cortex Ex has been broad studied on its chemical components, pharmacological activity, and clinical effects on anti-inflammation, anti-allergy, anti-tumor, immunity, antibacteria and other bioactivities. In this study, we investigated the therapeutic effects and action mechanism of Phellodendri Cortex Ex with a BPH induced by castration and testosterone treatment. Methods : Sprague-Dawley rats were treated with testosterone after castration for induction of experimental benign prostatic hyperplasia, which is similar to human benign prostatic hyperplasia in histopathological profiles. Phellodendri Cortex as an experimental specimen, and Finasteride as a positive control, were administered orally. The prostates were evaluated by histopathological changes, and the expression of $5{\alpha}$-reductase genes. Results : While prostates of control rats revealed severe acinar gland atrophy and stromal proliferation, the rats treated with Phellodendri Cortex Ex showed a diminished range of the tissue damage. In the reverse transcription-polymerase chain reaction(RT-PCR) of $5{\alpha}$-reductase genes, Phellodendri Cortex inhibited the expression of $5{\alpha}$-reductase genes. Conclusions : These findings suggest that Phellodendri Cortex Ex may protect the glandular epithelial cells and also inhibit stromal proliferation in association with the suppression of $5{\alpha}$-reductase. From these results, we suggest that Phellodendri Cortex Ex could be a useful agent for treating the benign prostatic hyperplasia.

Objectives : The objective of this study was to access the effect of Artemisiae capillaris herba Extracts on the organogenetic reproductive toxicity of New Zealand White rabbits when administered by oral gavage. Methods : Gestational New Zealand White rabbits were dosed from 6 days of gestation to 18 days of gestation. It was conducted in accordance with the recommendations of the KFDA Guideline for Detection of Toxicity to Reproduction for Medicinal Products. In addition, serum AST, ALT, LDH and ALP levels were detected with their necropsy and histopathological observation Results: No significant changes of body weights, gains and food consumption were demonstrated in all dosed groups compared to those of vehicle control group except for 2,000mg/kg-dosing group, which showed significantly increase of body weight compared to that of vehicle control group. Normal gross findings were demonstrated in all tested groups. No significant changes of number of corpora lutea, implantation, implantation rate, number of fetal death, loss rate of post-implantation, number of live youngs at C-section, survival rate of post-implantation, number of male live youngs at C-section, number of female live youngs, sex ratio of live young, external anomalies of live youngs and body weight of live youngs were demonstrated in all dosed groups compared to those of vehicle control group. Although some visceral variations such as thymic reminant in the neck, dilation of renal pelvis, dilated ureter and malpositioned left common carotid artery, no significant changes were demonstrated in all dosed groups compared to that of vehicle control group. Some malformations and variation were demonstrated with retardations. However, no significant changes were demonstrated in all dosed groups compared to that of vehicle control group. In addition, similar ossification numbers were detected in sternebrae, metacarpals, metatarsals, phalanges, cervical vertebrae, and sacral and caudal vertebrae. No Artemisiae capillaris herba Extracts treatment-related changes of serum AST, ALT, LDH and ALP levels were demonstrated in all dosed levels in this study. Conclusions : We could conclude that oral administration of Artemisiae capillaris herba Extracts hasn't an influence on the organogenetic reproductive toxicity.

Objective : The purpose of this study is to compare the Effect of Acupuncture on Local Acupoints and Distal Acupoints for Patients with Whiplash Injury. Method : From January 1st 2009 to September 31th 2009, 10 patient were divided into 2 groups. One group was taken Local Acupoints, and the other group was taken Distal Acupoints. To check pain and treatment satisfaction, visual analog scale(VAS) and five-point likert scale were used before and after treatment. Result : Both acupuncture theraphy showed improvement in VAS and five-point likert scale. And Local Acupoints group showed more effective than Distal Acupoints group on five-point likert scale. Conclusion : This Study suggests that Acupuncture on Local Acupoints and Distal Acupoints can be applicable to improve symptom in Patients with Whiplash Injury.

Objective : The present study has been undertaken to investigate the preventive effects of Daekumeumja on fatty degeneration of liver and immunosuppression induced by alcohol in rats. Method : Except for the normal group, we fed rat on 25% alcohol for 55 days. And Daekumeumja(DK) extract was administrated for the same period. We measured the serum component in rat's blood, weight of internal organs, liver triglyceride contents, histomorphometry and histopathological observation of internal organs. Results : 1. In the change measurement of serum components, DK group(50 mg/kg, 200 mg/kg) showed significant decrease of AST, ALT, albumin, ALP and triglyceride in comparison with those of the alcohol control group. 2. In the change measurement of internal organ's weight, DK group(50 mg/kg, 200 mg/kg) showed significant increase of relative body weights of liver, thymus and spleen in comparison with those of the alcohol control group. 3. DK group(50 mg/kg, 200 mg/kg) showed significant decrease of hepatic triglyceride contents in comparison with those of the alcohol control group. 4. In histomorphometrical changes of liver, DK group(50 mg/kg, 200 mg/kg) showed significant decrease of numbers of hepatocytes occupied by over 10% lipid droplets, percentages of regions occupied by lipid droplets and mean diameters of hepatocytes in comparison with those of the alcohol control group. In histomorphometrical changes of thymus, DK group(50 mg/kg, 200 mg/kg) showed significant increase of lobular thickness and cortex thickness in comparison with those of the alcohol control group. In histomorphometrical changes of spleen, DK group(50 mg/kg, 200 mg/kg) showed significant increase of splenic thicknesses, numbers of white pulps and mean diameters of white pulps in comparison with those of the alcohol control group. 5. In histopathological changes of liver, DK group(50 mg/kg, 200 mg/kg) showed effective inhibition of severe fatty changes in comparison with those of the alcohol control group. In histopathological changes of thymus and spleen, DK group(50 mg/kg, 200 mg/kg) showed effective inhibition of atrophic changes in comparison with those of the alcohol control group. Conclusions : Reviewing these experimental results, it appears that Daekumeumja have pharmaceutical preventive efficacy on fatty degeneration of liver and immunosuppression induced by alcohol in rats.

Objetcives : Cancer cachexia is a common syndrome in advanced cancer patients, which is characterized by profound changes in protein, fat and carbohydrate metabolism, resulting in anorexia, weight loss, muscle wasting and poor performance status. We studied the journals of Chinese herb medicine about cancer cachexia and reported the results. Methods : This study attempted to analyze the contents of the research papers concerning the treatment of cancer cachexia presented in the journals of Chinese medicine published in China over the period between 2000 and 2009. Results & Conclusions : The principles for medical treatment were invigorating Ki(益氣), invigorating the spleen(健脾), regulating the stomach(和胃), nourishing the blood(養血), nourishing Eum(補陰), promoting the circulation of Ki(行氣), removing the phlegm(化痰), removing blood stasis(祛瘀) etc. The used herbs were Poria(茯笭), Astragali Radix(黃芪), Atractylodis Macrocephalae Rhizoma(白朮), Codonopsis Pilosulae Radix(黨蔘), Dioscoreae Rhizoma(山藥), Citri Pericarpium(陳皮), Angelicae Gigantis Radix(當歸), Coicis Pemen(薏苡仁), Paeoniae Radix Alba(白芍藥) etc. The effetcive rate of treatment with Chinese herb medicine group was comparable or even more effetcive. Chinese herb medicine group had little side effetcs. Chinese medicine herb treatment to inhibit cancer cachexia has many possibilities.

Objectives : The directional supplementation and draining and twirling supplementation and draining have been used widely in oriental medical clinic. The aim of this study is to compare the effects between directional supplementation and draining method and twirling supplementation and draining. Methods : Clinical experiment was performed with 21 students of oriental medical college of Daegu Haany university. Acupuncture was applied at left Hapgok (LI4) with directional supplementation and twirling supplementation respectively, and the thermographic change was checked using DITI (Digital Infrared Thermographic Image). Results and Conclusion : A significant thermographic change was observed at bilateral Igan (LI2), Yanggye (LI5), Gokji (LI11), and Yeonghyang (LI20) in directional supplementation. A significant thermographic change was observed at bilateral Igan (LI2), Yanggye (LI5), and Yeonghyang (LI20) in twirling supplementation. Based on the thermographic change, it could be demonstrated that directional supplementation is more effective that twirling supplementation.