• Journal of the Korea Institute of Information and Communication Engineering
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• v.8 no.7
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• pp.1442-1447
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• 2004

In this paper, a 6-Bit CMOS Folding and Interpolating AD Converter is presented. The converter is considered to be useful as an integrated part of a VLSI circuit handling both analog and digital signals as in the case of HDD or LAN applications. A built-in analog circuit for VLSI of a high-speed data communication requires a small chip area, low power consumption, and fast data processing. The proposed folding and interpolating AD Converter uses a very small number of comparators and interpolation resistors, which is achieved by cascading a couple of folders working in different principles. This reduced number of parts is a big advantage for a built-in AD converter design. The design is based on 0.25m double-poly 2 metal n-well CMOS process. In the simulation, with the applied 2.5V and a sampling frequency of 500MHz, the measurements are as follows: power consumption of 27mw, INL and DNL of $\pm$0.1LSB, $\pm$0.15LSB each, SNDR of 42dB with an input signal of 10MHz.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.10 no.2
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• pp.141-146
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• 2017

In this paper, a gradient magnitude hardware architecture based on hardware folding design method is proposed for low power image feature extraction. For the hardware complexity reduction, the projection vector chracteristic of gradient magnitude is applied. The proposed hardware architecture can be implemented with the small degradation of the gradient magnitude data quality. The FPGA implementation result shows the 41% of logic elements and 62% embedded multiplier savings compared with previous work using Altera Cyclone VI (EP4CE115F29C7N) FPGA and Quartus II v16.0 environment.

• International Journal of Industrial Entomology and Biomaterials
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• v.7 no.2
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• pp.127-131
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• 2003

Protein disulfide isomerase (PDI) found in the endoplasmic reticulum (ER) catalyzes disulfide bond exchange and assists in protein folding of newly synthesized proteins. PDI also functions as a molecular chaperone and has been found to be associated with proteins in the ER. In addition, PDI functions as a subunit of two more complex enzyme systems: the prolyl-4-hydroxylase and the triacylglycerol transfer proteins. A cDNA that encodes protein disulfide isomerase was previously isolated from Bombyx mori (bPDI), in which open reading frame of 494 amino acids contained two PDI-typical thioredoxin active site of WCGHCK and an ER retention signal of the KDEL motif at its C-terminal, and we report its functional characterization here. This putative bPDI cDNA is expressed in insect Sf9 cells as a recombinant proteins using baculovirus expression vector system. The bPDI recombinant proteins are successfully recognized by antirat PDI antibody, and shown to be biologically active in vitro by mediating the oxidative refolding of reduced and scrambled RNase. This suggests that bPDI may play an important role in protein folding mechanism of insects.

• Journal of Applied Biological Chemistry
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• v.50 no.2
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• pp.58-62
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• 2007

Identification of Dual-specificity protein phosphatase (DSP) substrates is essential in revealing physiological roles of DSPs. We isolated VHZ-interacting proteins from extracts of 293T cells overexpressing a VHZ (C95S, D65A) mutant known to be substrate- trapping mutant. Analysis of specific proteins bound to VHZ by 2D gel electrophoresis and mass spectroscopy revealed that these proteins contained Chaperonin containing TCP1, Type II phosphatidylinositol phosphate kinase ${\gamma}$, Intraflagellar transport 80 homolog, and Kinesin superfamily protein 1B. VHZ-interacting proteins showed that VHZ is involved in many important cellular signal pathways such as protein folding, molecular transportation, and tumor suppression.

• International Journal of Aeronautical and Space Sciences
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• v.18 no.3
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• pp.588-600
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• 2017

We develop a wireless, contact free power transfer mechanism that is safer than the direct metallic contact and robust to imperfect alignment on landing at the base station. A magnetic field is created using inductors on both the transmitting and receiving sides. We use the inductive wireless recharging to increase autonomy and decrease the sensor interference by reducing the inductor loop size. By locating four independent small receiver loops and corresponding four circuits around the quadrotor UAV, we can increase safety from circuit malfunctions in comparison to the use of just one loop. On the base station, four folding robotic bars are used to realign the receiver loops over the transmitter loops. After adequate recharging as measured by battery voltages or power consumption at the bae station, the UAV sends a signal to the base station to open the robotic bars and takes off once freed from the robotic bars.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.4A
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• pp.336-344
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• 2005

Discrete Wavelet Transform(DWT) is the oncoming generation of compression technique that has been selected for MPEG4 and JEPG2000, because it has no blocking effects and efficiently determines frequency property of temporary time. In this paper, we propose an efficient bit-serial architecture for the low-power and low-complexity DWT filter, employing two-channel QMF(Qudracture Mirror Filter) PR(Perfect Reconstruction) lattice filter. The filter consists of four lattices(filter length=8) and we determine the quantization bit for the coefficients by the fixed-length PSNR(peak-signal-to-noise ratio) analysis and propose the architecture of the bit-serial multiplier with the fixed coefficient. The CSD encoding for the coefficients is adopted to minimize the number of non-zero bits, thus reduces the hardware complexity. The proposed folded 1D DWT architecture processes the other resolution levels during idle periods by decimations and its efficient scheduling is proposed. The proposed architecture requires only flip-flops and full-adders. The proposed architecture has been designed and verified by VerilogHDL and synthesized by Synopsys Design Compiler with a Hynix 0.35$\mu$m STD cell library. The maximum operating frequency is 200MHz and the throughput is 175Mbps with 16 clock latencies.

• Journal of the Institute of Convergence Signal Processing
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• v.21 no.3
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• pp.101-106
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• 2020

The utilization of virtual reality is increasing not only in games but also in medical care such as rehabilitation. Due to the convenience, the motion of the upper limb is detected using a non-contact method using video or a handheld type mouse, etc. In this paper, we implemented a glove which can measure finger movements and upper limb movements by using flex sensors whose resistance value changes according to the degree of folding and inertial sensors which can obtain direction information in space. We showed the upper arm movements including finger movements with signals obtained from the implemented glove on the open software platform, Processing. The sensitivity of each finger movement was 0.5deg, and the sensitivity of the upper limb motion was 0.6deg.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.6
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• pp.1516-1529
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• 2023

In this paper, a motor gearbox fault-detection system based on a hierarchical flow-based model is proposed. The proposed system is used for the anomaly detection of a motion sound-based actuator module. The proposed flow-based model, which is a generative model, learns by directly modeling a data distribution function. As the objective function is the maximum likelihood value of the input data, the training is stable and simple to use for anomaly detection. The operation sound of a car's side-view mirror motor is converted into a Mel-spectrogram image, consisting of a folding signal and an unfolding signal, and used as training data in this experiment. The proposed system is composed of an encoder and a decoder. The data extracted from the layer of the pretrained feature extractor are used as the decoder input data in the encoder. This information is used in the decoder by performing an interlayer cross-scale convolution operation. The experimental results indicate that the context information of various dimensions extracted from the interlayer hierarchical data improves the defect detection accuracy. This paper is notable because it uses acoustic data and a normalizing flow model to detect outliers based on the features of experimental data.

• Molecules and Cells
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• v.26 no.3
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• pp.228-235
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• 2008

Thiol-dependent redox systems are involved in regulation of diverse biological processes, such as response to stress, signal transduction, and protein folding. The thiol-based redox control is provided by mechanistically similar, but structurally distinct families of enzymes known as thiol oxidoreductases. Many such enzymes have been characterized, but identities and functions of the entire sets of thiol oxidoreductases in organisms are not known. Extreme sequence and structural divergence makes identification of these proteins difficult. Thiol oxidoreductases contain a redox-active cysteine residue, or its functional analog selenocysteine, in their active sites. Here, we describe computational methods for in silico prediction of thiol oxidoreductases in nucleotide and protein sequence databases and identification of their redox-active cysteines. We discuss different functional categories of cysteine residues, describe methods for discrimination between catalytic and noncatalytic and between redox and non-redox cysteine residues and highlight unique properties of the redox-active cysteines based on evolutionary conservation, secondary and three-dimensional structures, and sporadic replacement of cysteines with catalytically superior selenocysteine residues.

• Smart Media Journal
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• v.3 no.1
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• pp.39-45
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• 2014

The partial product matrix of a parallel squarer are symmetric about the diagonal. To reduce the number of partial product bits and the depth of partial product matrix, it can be typically folded, shifted and bit-rearranged. In this paper, an efficient design approach for the combined squarer, capable of operating on either unsigned or signed numbers based on a mode selection signal, is presented. By simulations, it is shown that the proposed combined squarers lead to up to 18% reduction in area, 11% reduction in propagation delay and 9% reduction in power consumption compared with the previous combined squarers.