• Title/Summary/Keyword: 논문 리뷰

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Analysis of Automotive HMI Characteristics through On-road Driving Research (실차 주행 연구를 통한 차량별 HMI 특성 분석)

  • Oh, Kwangmyung
    • Journal of the HCI Society of Korea
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    • v.14 no.2
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    • pp.49-60
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    • 2019
  • With the appearance of self-driving cars and electric cars, the automobile industry is rapidly changing. In the midst of these changes, HMI studies are becoming more important as to how the driver obtains safety and convenience with controlling the vehicle. This study sought to understand how automobile manufacturers understand the driving situation, and how they define and limit driver interaction. For this, prior studies about HMI were reviewed and 15 participants performed an on-road study to drive vehicles from five manufacturers with using their interfaces. The results of the study confirmed that buttons and switches that are easily controlled by the user while driving were different from manufacturer to manufacturer. And there are some buttons that are more intensively controlled and others that are difficult to control while driving. It was able to derive 'selection and concentration' from Audi's vehicle, 'optimization of the driving ' from BMW's, 'simple and minimize' from Benz's vehicle, 'remove the manual distraction' from the vehicle of Lexus, and 'visual stability' from KIA's vehicle as the distinctive keywords for the HMI. This shows that each manufacturer has a different definition and interpretation of the driver's driving control area. This study has a distinct value in that it has identified the characteristics of vehicle-specific HMI in actual driving conditions, which is not apparent in appearance. It is expected that this research approach can be useful to see differences in interaction through actual driving despite changes in driving environment such as vehicle platooning and self-driving technology.

Study on the Retrieval of Vertical Air Motion from the Surface-Based and Airborne Cloud Radar (구름레이더를 이용한 대기 공기의 연직속도 추정연구)

  • Jung, Eunsil
    • Atmosphere
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    • v.29 no.1
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    • pp.105-112
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    • 2019
  • Measurements of vertical air motion and microphysics are essential for improving our understanding of convective clouds. In this paper, the author reviews the current research on the retrieval of vertical air motions using the cloud radar. At radar wavelengths of 3 mm (W-band radar; 94-GHz radar; cloud radar), the raindrop backscattering cross-section (${\sigma}b$) varies between successive maxima and minima as a function of the raindrop diameter (D) that are well described by Mie theory. The first Mie minimum in the backscattering cross-section occurs at D~1.68 mm, which translates to a raindrop terminal fall velocity of ${\sim}5.85m\;s^{-1}$ based on the Gunn and Kinzer relationship. Since raindrop diameters often exceed this size, the signal is captured in the radar Doppler spectrum, and thus, the location of the first Mie minimum can be used as a reference for retrieving the vertical air motion. The Mie technique is applied to radar Doppler spectra from the surface-based and airborne, upward pointing W-band radars. The contributions of aircraft motion to the vertical air motion are also described and further the first-order aircraft motion corrected equation is presented. The review also shows that the separate spectral peaks due to the cloud droplets can provide independent validation of the Mie technique retrieved vertical air motion using the cloud droplets as a tracer of vertical air motion.

The Significance of Cancer Stem Cells in Canine Mammary Gland Tumors (개 유선종양 내 종양줄기세포의 중요성)

  • Park, Seo-Young;Baek, Yeong-Bin;Park, Sang-Ik;Lee, Chang-Min;Kim, Sung-Hak
    • Journal of Life Science
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    • v.31 no.2
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    • pp.248-255
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    • 2021
  • Mammary gland tumors are one of the most common cancers in female dogs, and there are various types of cells depending on the tumor type. Complex carcinoma consists of a combination of luminal epithelial and myoepithelial cells with intra-tumoral heterogeneity. However, the origins of these tumor cells and their effects on the malignancies of tumors have not been identified. Recently, it has been reported that cancer stem cells, identified in several types of human tumors, are involved in tumor heterogeneity and may also contribute to malignancies such as tumor recurrence and metastasis. Interestingly, cancer stem cells share several abilities of self-renewal and cell differentiation into multiple types of cancer cells, but they have abnormal genetic mutation and signal transduction pathways to regulate the maintenance of stem cell characters. Moreover, it is known that these cell populations contribute to cell metastasis as well as cell resistance against chemo- and radio-therapeutics that promote tumor recurrence. The existence of cancer stem cells might explain the intra-tumoral heterogeneity and cancer aggressiveness during tumorigenesis in canine mammary gland tumors. This review summarizes the characteristics and types of canine mammary gland tumors, the definition of tumor stem cells, methods of isolation, and clinical significance.

Transcriptional Regulation of Lipogenesis and Adipose Expansion (Lipogenesis와 adipose expansion의 전사조절)

  • Jang, Younghoon
    • Journal of Life Science
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    • v.32 no.4
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    • pp.318-324
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    • 2022
  • PPARγ and C/EBPα are master adipogenic transcription factors (TFs) required for adipose tissue development. They control the induction of many adipocyte genes and the early phase of adipogenesis in the embryonic development of adipose tissue. Adipose tissue continues to expand after birth, which, as a late phase of adipogenesis, requires the lipogenesis of adipocytes. In particular, the liver and adipose tissues are major sites for de novo lipogenesis (DNL), where carbohydrates are primarily converted to fatty acids. Furthermore, fatty acids are esterified with glycerol-3-phosphate to produce triglyceride, a major source of lipid droplets in adipocytes. Hepatic DNL has been actively studied, but the DNL of adipocytes in vivo remains not fully understood. Thus, an understanding of lipogenesis and adipose expansion may provide therapeutic opportunities for obesity, type 2 diabetes, and metabolic diseases. In adipocytes, DNL gene expression is transcriptionally regulated by lipogenesis coactivators, as well as by lipogenic TFs such as ChREBP and SREBP1a. Recent in vivo studies have revealed new insights into the lipogenesis gene expression and adipose expansion. Future detailed molecular mechanism studies will determine how nutrients and metabolism regulate DNL and adipose expansion. This review will summarize recent updates of DNL in adipocytes and adipose expansion in terms of transcriptional regulation.

Direction of Emergency Rescue Education Based on the Experience of New 119 Paramedics for National Health Promotion (국민건강증진을 위한 응급구조학 교육의 나아갈 방향 -신임 119구급대원의 출동경험을 바탕으로-)

  • Kim, Jung-Sun
    • Journal of Korea Entertainment Industry Association
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    • v.15 no.1
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    • pp.207-220
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    • 2021
  • The purpose of the study is to investigate the application and utility of emergency rescue education and derive limitations, improvements and development directions of university education based on the field experience of 119 emergency medical technician(EMT)s. The research subjects were six new 119 emergency medical technician(EMT)s within three years of starting their first-aid service in the field. After conducting in-depth narrative interviews, the analysis was performed using Colaizzi method. The 82 formulated meanings were derived from significant statements. From formulated meanings, 23 themes, 4 theme clusters, 2 categories were identified. The four theme clusters were 'The effectiveness of university education', 'The limitations of university education', 'The direction of improvement in educational methodology' and 'The direction of improvement in educational contents. University education has been helpful overall, but limitations are observed at the same time, suggesting that it should be developed through the improvement of educational methodologies (i.e. problem-based learning, field case review, education through role-playing, simulation education, strengthening skill ect.) and educational content (i.e. training tailored to the field, education focused on trauma or cardiac arrest, expansion of triage education in disaster management, reinforcement of education on-site safety, education on special patients, diverse guidance and faculty for different perspectives).

Systematic Review on Outcome and Trends of Community Care Pilot Project in Korea (국내 지역사회 통합돌봄 선도사업 성과 및 동향에 관한 체계적 문헌고찰)

  • Kim, Kyoung-Beom;Heo, Min-Hee;Jang, Ha-Eun;Noh, Jin-Won;Kim, Jang-Mook
    • Journal of Convergence for Information Technology
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    • v.12 no.5
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    • pp.159-167
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    • 2022
  • At the present time, no systematic review has been conducted to report the project's outcomes or trends. This study systematically reviewed existing evidence related with community care pilot project. A total of 61 articles, including 18 original literatures and 43 review literatures were finally selected. For original literatures, the most frequent literatures focused on demand surveys (n=4) and model proposals (n=4), the utilization of touchpoint (n=3), space design and architectural model (n=3), manpower training and role establishment (n=2), followed by prioritizing objectives (n=1) and research trend study (n=1). For review literatures, the most frequent literature focused on the elderly (n=12) and relatively few literature on the disabled and mental illness (n=2). Since the pilot project for community care has been implemented for only about one year, the present study indicates that more future research is needed to the disabled, mental illness, and homeless should be conducted as well as elderly.

Chemical Prelithiation Toward Lithium-ion Batteries with Higher Energy Density (리튬이온전지 고에너지밀도 구현을 위한 화학적 사전리튬화 기술)

  • Hong, Jihyun
    • Journal of the Korean Electrochemical Society
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    • v.24 no.4
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    • pp.77-92
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    • 2021
  • The energy density of lithium-ion batteries (LIBs) determines the mileage of electric vehicles. For increasing the energy density of LIBs, it is necessary to develop high-capacity active materials that can store more lithium ions within constrained weight. The rapid progress made in cathode technology has realized the utilization of the near-theoretical capacity of cathode materials. In contrast, commercial LIBs have still exploited graphite as active material in anodes since the 1990s. The most promising way to increase anodes' capacity is to mix high-capacity and long-cycle-life silicon oxides (SiOx) with graphite. However, the low initial Coulombic efficiency (ICE) of SiOx limits its content below 15 wt%, impeding the capacity increase in anodes. To address this issue, various prelithiation techniques have been proposed, which can improve the ICE of high-capacity anode materials. In this review paper, we introduce the principles and expected effects of prelithiation techniques reported so far. According to the reaction mechanisms, the strategies are categorized. Mainly, we focus on the recent progress of solution-based chemical prelithiation methods with commercial viability, of which lithiation reaction occurs homogeneously at liquid-solid interfaces. We believe that developing a cost-effective and mass-scalable prelithiation process holds the key to dominating the anode market for next-generation LIBs.

Upper Mantle Heterogeneity Recorded by Microstructures and Fluid Inclusions from Peridotite Xenoliths Beneath the Rio Grande Rift, USA (미국 리오 그란데 리프트 페리도타이트 포획암의 미구조와 유체포유물에 기록된 상부맨틀의 불균질성)

  • Park, Munjae
    • Korean Journal of Mineralogy and Petrology
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    • v.35 no.3
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    • pp.273-281
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    • 2022
  • Mantle heterogeneity is closely related to the distribution and circulation of volatile components in the Earth's interior, and the behavior of volatiles in the mantle strongly influences the rheological properties of silicate rocks. In mantle xenoliths, these physicochemical properties of the upper mantle can be recorded in the form of microstructures and fluid inclusions. In this paper, I summarized and reviewed the results of previous studies related to the characteristics of microstructures and fluid inclusions from peridotite xenoliths beneath the Rio Grande Rift (RGR) in order to understand the evolution and heterogeneity of upper mantle. In the RGR, the mantle peridotites are mainly reported in the rift axis (EB: Elephant Butte, KB: Kilbourne Hole) and rift flank (AD: Adam's Diggings) regions. In the case of the former (EB and KB peridotites), the type-A lattice preferred orientation (LPO), formed under low-stress and low-water content, was reported. In the case of the latter (AD peridotites), the type-C LPO, formed under low-stress and high-water content, was reported. In particular, in the case of AD peridotites, at least two fluid infiltration events, such as early (type-1: CO2-N2) and late (type-2: CO2-H2O), have been recorded in orthopyroxene. The upper mantle heterogeneity recorded by these microstructures and fluid inclusions is considered to be due to the interaction between the North American plate and the Farallon plate.

Biogeochemistry of Methane in Water and Sediment: Methane Generation in Coastal Areas with Bottom Water Hypoxia (메탄의 생지화학적 거동과 한국 연안해역 저(빈)산소 층 발달에 따른 메탄 생성)

  • DONGJOO JOUNG
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.28 no.3
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    • pp.95-120
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    • 2023
  • Methane (CH4) is a key greenhouse gas in the atmosphere with 85 times greater greenhouse potent relative to carbon dioxide (CO2). The atmospheric concentration of CH4 is rapidly increasing due to the intensive usage of CH4 and the thawing of the cryosphere. Additionally, with the current warming of ocean water, the dissociation of gas hydrates, an ice-like compound and the largest reservoir of CH4 on Earth, is expected to occur, resulting in the release of CH4 from the seafloor into the overlying water and atmosphere. Moreover, bottom water hypoxia is another concern that potentially introduces greenhouse gases into the atmosphere. With ongoing global warming and eutrophication, the size and duration of bottom water hypoxia are rapidly increasing. These low-oxygen conditions would relocate the redox zone shallower in sediment or in the water column, causing the release of CH4 into the atmosphere and thereby intensifying global warming. However, there exists a gap in the understanding of CH4 dynamics including its generation in relation to bottom water hypoxia. Therefore, this review article aims to understand the relationship between CH4 and bottom water hypoxia and to draw attention to CH4 investigation in Korea.

Analysis of Research Trends in New Drug Development with Artificial Intelligence Using Text Mining (텍스트 마이닝을 이용한 인공지능 활용 신약 개발 연구 동향 분석)

  • Jae Woo Nam;Young Jun Kim
    • Journal of Life Science
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    • v.33 no.8
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    • pp.663-679
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    • 2023
  • This review analyzes research trends related to new drug development using artificial intelligence from 2010 to 2022. This analysis organized the abstracts of 2,421 studies into a corpus, and words with high frequency and high connection centrality were extracted through preprocessing. The analysis revealed a similar word frequency trend between 2010 and 2019 to that between 2020 and 2022. In terms of the research method, many studies using machine learning were conducted from 2010 to 2020, and since 2021, research using deep learning has been increasing. Through these studies, we investigated the trends in research on artificial intelligence utilization by field and the strengths, problems, and challenges of related research. We found that since 2021, the application of artificial intelligence has been expanding, such as research using artificial intelligence for drug rearrangement, using computers to develop anticancer drugs, and applying artificial intelligence to clinical trials. This article briefly presents the prospects of new drug development research using artificial intelligence. If the reliability and safety of bio and medical data are ensured, and the development of the above artificial intelligence technology continues, it is judged that the direction of new drug development using artificial intelligence will proceed to personalized medicine and precision medicine, so we encourage efforts in that field.