In this paper, we investigate the effect of production uncertainty - especially demand fluctuation and activity time variation, to production control policies. First, we examine three famous production control policies, namely, MRP, JIT, OPT, from shop floor control perspective and analyze the difference among them. Based on these, simulation studies are performed to draw out the effects of demand fluctuation which are classified into demand lumpiness and demand irregularity, and, the effects of activity time variation which are classified into standard time variation and non-standard time variation. Experimental investigation shows that, in terms of demand fluctuations, MRP is affected by demand lumpiness, but JIT by demand irregularity. And we also see that both MRP and JIT are influenced by standard time variation with respect to activity time variations.