• 제목/요약/키워드: punica granatum

검색결과 72건 처리시간 0.031초

중국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색 (IV) (Screening of Chinese Herbal Medicines with Inhibitory Effect on Aldose Reductase (IV))

  • 이윤미;김영숙;배기환;김주환;김진숙
    • 생약학회지
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    • 제41권4호
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    • pp.289-296
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    • 2010
  • Aldose reductase (AR), the principal enzyme of the polyol pathway, has been shown to play an important role in the development of the diabetic complications. Evaluating natural sources for ARI potential may lead to the development of safer and more effective agents against diabetic complications. Sixty four Chinese herbal medicines have been investigated for inhibitory activities on AR. Among them, thirteen herbal medicines, Inula helianthus-aquatilis C. Y. Wu ex Ling. (whole plant), Erigeron breviscapus (Vant.) Hand. Mazz. (whole plant), Lonicera hypoglauca Miq. (leaf, stem), Scutellaria orthocalyx Hang. Mazz. (whole plant), Berchemia floribunda Brongn. (leaf, stem), Michelia alba DC. (flower), Oroxylum indicum (seed), Punica granatum L. (peel), Elsholtzia capituligera (whole plant), Trachelospermum jasminoides (Lindl.) Lem. (whole plant), Elsholtzia strobilifera Benth. (whole plant), Agrimonia pilosa var. nepalensis (D. Don) Nakai (whole plant) and Aster poliothamnus Diels (whole plant) exhibited a significant inhibitory activity against AR. Particularly, Inula helianthus-aquatilis C. Y. Wu ex Ling. showed seven times more potent inhibitory activity than the positive control, 3,3-tetramethyleneglutaric acid (TMG).

Effect of antidiarrhoeal formulation on acute experimental diarrhoea in rats

  • Khan, M. Aleem;Khan, Naeem A.;Qasmi, Iqbal A.;Ahmad, Ghufran;Zafar, Shadab
    • Advances in Traditional Medicine
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    • 제5권2호
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    • pp.150-155
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    • 2005
  • Aqueous extract of antidiarrhoeal formulation (ADF) containing Holarrhena antidysentrica, Aegle marmelos and Punica granatum was investigated for antidiarrhoeal activity against charcoal-induced gut transit, serotonin-induced diarrhoea and $PGE_2-induced$ small intestine enteropooling in rats. The control, standard and test groups of experimental animals were administered with normal saline (p.o.), diphenoxylate hydrochloride (5 mg/kg, p.o.) and ADF (250 mg and 500 mg/kg, p.o.) respectively except the control group of $PGE_2-induced$ small intestine enteropooling which received only 5% ethanol in normal saline (i.p.). Charcoal (10 ml/kg, p.o.) and serotonin $(600\;{\mu}g/kg,\;i.p.)$ were administered after 30 min, while $PGE_2\;(100\;{\mu}g/kg,\;p.o.)$ was administered immediately afterwards. The distance traveled by charcoal in small intestine was measured after 15 and 30 min of charcoal administration, diarrhoea was observed every 30 min for six hour after serotonin administration and the volume of intestinal fluid was measured after 30 min of $PGE_2$ administration. Oral administration of ADF significantly inhibited the frequency of defaecation and decreased the propulsion of charcoal meal through the gastrointestinal tract, reduced the wetness of faecal dropping in serotonin-induced diarrhoea and also reduced the $PGE_2-induced$small intestine enteropooling. ADF may have potential to reduce the diarrhoea in rats.

Pomegranate (Punica granatum) Peel Extract Efficacy as a Dietary Antioxidant against Azoxymethane-Induced Colon Cancer in Rat

  • Waly, Mostafa I.;Ali, Amanat;Guizani, Nejib;Al-Rawahi, Amani S.;Farooq, Sardar A.;Rahman, Mohammad S.
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권8호
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    • pp.4051-4055
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    • 2012
  • Functional foods include antioxidant nutrients which may protect against many human chronic diseases by combating reactive oxygen species (ROS) generation. The purpose of the present study was to investigate the protective effect of pomegranate peel extract (PPE) on azoxymethane (AOM)-induced colon tumors in rats as an in vivo experimental model. Forty Sprague-Dawley rats (4 weeks old) were randomly divided into 4 groups containing 10 rats per group, and were treated with either AOM, PPE, or PPE plus AOM or injected with 0.9% physiological saline solution as a control. At 8 weeks of age, the rats in the AOM and PPE plus AOM groups were injected with 15 mg AOM/kg body weight, once a week for two weeks. After the last AOM injection, the rats were continuously fed ad-libitum their specific diets for another 6 weeks. At the end of the experiment (i.e. at the age of 4 months), all rats were killed and the colon tissues were examined microscopically for lesions suspected of being preneoplastic lesions or tumors as well as for biochemical measurement of oxidative stress indices. The results revealed a lower incidence of aberrant crypt foci in the PPE plus AOM administered group as compared to the AOM group. In addition, PPE blocked the AOM-induced impairment of biochemical indicators of oxidative stress in the examined colonic tissue homogenates. The results suggest that PPE can partially inhibit the development of colonic premalignant lesions in an AOM-induced colorectal carcinogenesis model, by abrogating oxidative stress and improving the redox status of colonic cells.

석류 분말을 첨가한 양갱의 품질 특성 (Quality Characteristics of Yanggaeng containing Pomegranate (Punica granatum) Powder)

  • 길나영;김혜리;박종민;김산성;이의석;홍순택
    • 한국식품영양학회지
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    • 제27권5호
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    • pp.906-913
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    • 2014
  • The purpose of this study was to investigate the quality characteristics of white bean based Yanggaeng containing various levels of pomegranate powder (0, 2, 4 and 8%, w/w). The pH values of Yanggaeng containing pomegranate powder were found to decrease when increasing the amount of pomegranate powder. However, moisture and sugar contents were increased (p<0.05). For color values, both L and b values were reduced by increasing the amount of pomegranate powder, while a values were increased significantly (p<0.05). In textural properties, the addition of pomegranate powder resulted in the increase of hardness, chewiness and gumminess, while cohesiveness and springiness decreased. Antioxidant activities, evaluated by DPPH radical scavenging capacity, and total phenolic substances content increased when increasing the amount of pomegranate powder. Results of descriptive analysis showed that by increasing the amount of pomegranate powder, some attributes such as the intensity of the flavor, sourness, hardness and chewiness increased (p<0.05), but there was no statistically significant difference in sweetness. In a preference test, Yanggaeng containing 4% pomegranate powder appeared to be the most preferred for all attributes tested including overall acceptability. It was concluded that Yanggaeng containing pomegranate can be prepared with good sensory properties and antioxidant activities, and the addition of 4% pomegranate powder was found to be ideal.

LC/MS/MS를 이용한 석류추출물 중의 에스트로겐 분석 (Analysis of Estrogen in Pomegranate Extract by Solid Phase Extraction and Liquid Chromatography Tandem Mass Spectrometry)

  • 금은주;권도형;신혜승
    • 한국식품위생안전성학회지
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    • 제25권1호
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    • pp.79-82
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    • 2010
  • 석류는 오래전부터 임상치료 및 식품원료로 사용되었으며 많은 피토에스트로겐 성분을 함유하고 있다. 그 성분으로는 에스트론, 에스트라디올, 에스트리올, 베타-시토스테롤, 엘라그산 등이 였으며 이러한 성분으로 인해 과즙, 껍질, 오일 등은 약한 에스트로겐 활성을 나타낸다고 보고되었으며, 이로 인해 석류는 여성 갱년기 치료용 원료로 많이 사용되고 있다. 그러나 에스트로겐 성분의 존재 유무에 대한 견해의 차이가 나타나고 있어 본 연구는 LC/MS/MS를 이용하여 석류추출물 중의 에스트로겐 분석을 통해 이를 확인하고자 하였으며, 간편하고 정확한 분석법을 모색하고자 하였다. 3개 롯트 시료의 에스트로겐을 분석한 결과, 에스트론 83.5ppb, 에스트라디올 10.9ppb 및 에스트리올 38.6ppb로 검출되었다.

석류 껍질 분말을 첨가한 찐빵의 품질특성 (Quality Characteristics of Steamed Bread Containing Pomegranate (Punica granatum L.) Peel Powder)

  • 장양양;송가영;오현빈;정기영;신소연;김영순
    • 한국식품조리과학회지
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    • 제33권1호
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    • pp.54-64
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    • 2017
  • Purpose: Pomegranate has been reported to exhibit medical properties such as antimicrobial, antimutagenic, anticancer, and anti-inflammatory effects. Especially the pomegranate peel as a by-product of the juice industry possesses more polyphenols with an antioxidant effect than the pomegranate flesh does. This study aimed to investigate the effect of the pomegranate peel on the quality characteristics of steamed bread. Methods: Steamed bread containing pomegranate peel was prepared with 0%, 1%, 3%, 5%, and 7% replacements of wheat flour with pomegranate peel powder, respectively. Results: The pH of dough significantly decreased from 5.66 to 4.42 with the amounts of pomegranate peel powder rising. After a 1st fermentation, the pH of all groups decreased. With an increase of the pomegranate peel powder level, the fermentation tension decreased from 42.83 mL to 29.03 mL. In addition, the volume, the specific volume, and moisture decreased as the pomegranate peel powder content level heightened. For color, steamed bread added with 7% pomegranate peel powder displayed low lightness but high redness and yellowness. In texture analysis, hardness and chewiness of the steamed bread rose as the pomegranate peel powder content increased, while the springiness and cohesiveness declined. Both total polyphenol and DPPH radical scavenging activity significantly increased with growing levels of pomegranate peel powder. In a sensory evaluation, the group with 1% pomegranate peel powder added showed the highest sensory preference scores for color, flavor, chewiness, taste, and overall acceptability. Conclusion: The results of this study suggest that steamed bread prepared with the addition of 1% pomegranate peel powder is the most optimal product for appropriate quality characteristics.

한국에서 새로운 해충 석류가루이, Siphoninus phillyreae (Haliday, 1835) 발견 보고 (First Report of Ash whitefly, Siphoninus phillyreae (Haliday, 1835) (Hemiptera: Aleyrodidae) in Korea)

  • 이흥수;박덕기;이석민;이관석;이종호;홍기정;이원훈
    • 한국응용곤충학회지
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    • 제59권3호
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    • pp.251-255
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    • 2020
  • 2019년 경남 진주시 배나무에서 석류가루이(신칭) Siphoninus phillyreae (Haliday, 1835) 가 발견되었다. 분포조사를 통하여, 부산, 창원, 진주, 광양, 순천, 고흥, 고성에서 발생을 확인하였고, 기주식물로 석류, 배, 모과, 매실, 산사, 비파, 홍가시, 피라칸타, 배롱나무, 꽃사과나무를 확인하였다. 이 해충의 피해 상황과 분류학적 특징을 기재한다.

Natural Extracts as Inhibitors of Microorganisms and Lipid Oxidation in Emulsion Sausage during Storage

  • Lee, Jeeyeon;Sung, Jung-Min;Cho, Hyun Jin;Woo, Seung-Hye;Kang, Min-Cheol;Yong, Hae In;Kim, Tae-Kyung;Lee, Heeyoung;Choi, Yun-Sang
    • 한국축산식품학회지
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    • 제41권6호
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    • pp.1060-1077
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    • 2021
  • Food additives are required to maintain the freshness and quality of foods, particularly meats. However, chemical additives may not be preferred by consumers, and natural materials with antimicrobial and antioxidant effects may be used as replacements for common chemical additives. Accordingly, in this study, we compared the antimicrobial and antioxidant activities of natural compounds extracted with ethanol and hot water, and emulsion sausage prepared with natural ethanol extracts was analyzed for pH, color, thiobarbituric acid reactive substances (TBARS), and Clostridium perfringens growth during storage. The antimicrobial activities of 49 natural extract candidates against Listeria monocytogenes, C. perfringens, Salmonella spp., and Escherichia coli were analyzed, and six natural materials with excellent antibacterial activities, i.e., Elaeagnus umbellata Thunb. f. nakaiana (Araki) H. Ohba, Punica granatum L., Ecklonia cava, Nelumbo nucifera Gaertner, and Schisandra chinensis (Turcz.) Baill., and Rubus coreanus Miq. were evaluated to determine their total polyphenol contents and DPPH radical scavenging activities. The total polyphenol contents of ethanol extracts were higher than those of hot water extracts, whereas DPPH radical scavenging activity was found to be higher in hot water extracts. The TBARS values of emulsion sausages were significantly increased as storage time increased, and the TBARS values of emulsion sausages prepared with natural extracts were lower than those of control sausages. Natural extract-treated emulsion sausages showed a 99% reduction in bacterial contents compared with untreated sausages on day 2, with greater than 99.9% reduction after day 3. Thus, these results demonstrated that natural extracts could have applications as natural preservatives in meat products.

Antibacterial Activity of Selected Fruit Juices against Multidrug-Resistant Bacterial Pathogens Involved in Urinary Tract and Sexually Transmitted Infections among Tribal Women in Madhya Pradesh, India

  • Poonam Sharma;Juhi;Vaishali Halwai;Sainivedita Rout;Rambir Singh
    • 대한약침학회지
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    • 제26권3호
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    • pp.265-275
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    • 2023
  • Objectives: The aim of this study was to evaluate the effect of fruit juices on Multi-Drug Resistant (MDR) bacterial pathogens involved in Urinary Tract Infections (UTIs) and Sexually Transmitted Infections (STIs) among tribal women in the district Anuppur, Madhya Pradesh, India. Methods: Fresh juices of lemon (Citrus limon), amla/Indian gooseberry (Phyllanthus emblica), pineapple (Ananas comosus), mosambi/sweet lime (Citrus limetta), orange (Citrus sinensis), kiwi (Actinidia deliciosa), and pomegranate (Punica granatum) fruits were evaluated for in vitro antibacterial activity against bacterial pathogens involved in UITs and STIs among tribal women. Physico-chemical analysis of fresh fruits was also carried out by measuring the pH, moisture, protein, fat, crude fibre, carbohydrate, and ascorbic acid content. Results: Lemon and amla juice showed better antibacterial activity against the pathogens as compared to other juices. MIC results fruit juices against UTIs and STIs pathogens vary depending on the specific pathogen and juice chemical constituents. The physico-chemical analysis showed that the moisture content was highest in mosambi (90%), followed by orange (87%). Ascorbic acid content was found highest in amla (540 mg/100 g), followed by kiwi (90.3 mg/100 g). Pomegranate showed highest concentration of carbohydrate (15.28 g/100 g), fat (1.28 g/100 g), and protein (1.65 g/100 g). Lemon juice had lowest pH of 2.20, followed by amla 2.67. Conclusion: The lemon juice showed highest antibacterial activity against MDR bacterial pathogens involved in UTIs and STIs among tribal women in district Anuppur, Madhya Pradesh, India. The low pH of lemon may be responsible for its high antibacterial activity as compared to other juices.

전통조경에서 분(盆)을 이용한 식물의 활용과 애호 행태 (Plant Species Utilization and Care Patterns Using Potted Plants in the Traditional Gardening)

  • 김명희
    • 한국전통조경학회지
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    • 제31권3호
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    • pp.61-74
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    • 2013
  • 본 연구는 선조들이 궁궐이나 사가(私家)의 정원에 분을 이용하여 식물을 완상한 실증적인 사례들에 대하여 고문헌과 고전시문을 고찰하고 해석하여, 분에 식재된 식물소재와 분식물의 수형 및 식재기법 그리고 분식물의 배치와 애호행태 등을 고찰하였다. 연구의 방법은 분식물을 주제로 한 시문과 회화를 고찰하고 해석하는 기술(description)적 연구방법을 사용하였다. 본 연구의 결과를 요약하면 다음과 같다. 첫째, 분에 식재되어 애용된 식물로 목본류는 매화나무와 소나무를 비롯하여 만년송, 대나무, 동백나무, 석류나무, 치자나무 등 19종이고, 초본류는 국화와 연(蓮)을 비롯하여 12종이다. 둘째, 수형을 인위적으로 각별하게 가꾼 수종은 매화나무와 소나무로 두 식물은 왕피나 규반, 반간 등 줄기의 굴곡이 심한 생김새의 수형을 만들었으며, 기이한 등걸에 접붙인 매화나무와 괴석 위에 뿌리를 뻗게 석부하여 수형을 가꾼 소나무 분재도 있다. 분재의 수형미를 위해 노송에 솔방울을 달거나 줄기에 담쟁이덩굴을 식재하기도하고, '종분취경'이라 하여 분토에 이끼가 생기게 하는 부가적인 방법도 활용하였다. 식재기법으로 수경재배, 석부작, 숯부작, 모아심기 등도 시문에 표현되어 있다. 셋째, 분식물이 배치된 외부공간으로는 궁궐의 연조공간이나 연침공간, 사가의 건물 주변과 마당, 섬돌 위 등에 놓여 점경물 역할을 하였다. 분식물은 서재나 사랑방의 탁자나 책상, 문갑 위, 베갯머리 등에 놓여 실내공간의 소품 역할을 하며, 선비들은 이들 분식물의 고유의 특성과 상징성에서 의미를 취하여 즐겼다. 넷째, 분매(盆梅)의 개화시기에는 시회를 열어 매화를 감상하고 술을 마시며 시작활동을 하였으며, 국화 개화시는 술잔에 띄우거나 그림자놀이 등 풍류를 즐겼다. 다섯째, 분식물은 궁궐이나 사대부들의 아취 있는 모임이나 결혼식과 제사 등의 행사에서 점경물의 역할을 하였다. 여섯째, 분식물은 국가 간의 공물로 사용되기도 하고, 왕에게 드리는 진상품이나 왕의 하사품으로 이용되기도 하였다. 또한 선비들 사이에도 분식물을 주고받은 사례가 많으며, 목은 이색의 목은시고 에 분매를 선물한 최초의 기록이 있다. 일곱째, 분매와 분국, 분치, 분연 및 분에 심은 수선화 등의 개화시에 이들 식물의 고유의 향기를 즐기며, 시문으로 표현하였다. 여덟째, 동백나무, 서향화, 치자나무, 귤나무, 대나무, 석류나무, 해당화, 파초 등 남부수종이나 외래수종 및 내한성이 약한 종은 엄동설한에 중부이북지방의 실내에서 푸르름을 즐기기 위하여 분에 심어 활용되었다.