• Proceedings of the Korean Society of Applied Pharmacology
• /
• 2008.04a
• /
• pp.119-142
• /
• 2008

Zizyphi Spinosi Semen (ZSS) has been widely used for the treatment of anxiety and insomnia in Korea and China. This experiment was performed to know whether sanjoinine A, one of major alkaloid compounds of ZSS has anxiolytic and hypnotic effects through the GABAergic systems. Our results showed that administration of sanjoinine A increased open arm entries and spent time in open arm in the elevated plus-maze and increased head dips in hole board test. Different from traditional anxiolytic, diazepam, sanjoinine A itself did not decrease locomotor activity and strength level in mice. Furthermore, Sanjoinine A (0.5-2.0 mg/kg) prolonged sleeping time and reduced sleeping latency induced by pentobarbital in a dose-dependent manner similar to muscimol, a $GABA_A$ receptor agonist. Sanjoinine A (0.25-1.0 mg/kg) also increased sleeping rate and sleeping time in the combined administration at the sub-hypnotic dose of pentobarbital and showed synergic effects with muscimol in potentiating sleeping onset and enhancing sleeping time induced by pentobarbital. However, sanjoinine A itself did not induce sleeping at the higher dose. In addition, both of sanjoinine A and pentobarbital increased chloride influx in primary cultured cerebellar granule cells. Sanjoinine A decreased the $GABA_A$ receptor ${\alpha}$-subunit expression and increased ${\gamma}$-subunit expression, and had no effects on abundance of ${\beta}$-subunit in primary cultured cerebellar granule cells, showing different expression of subunits from pentobarbital. In conclusion, sanjoinine A shows anxiolytic-like effects and augments pentabarbital-induced sleeping behaviors through the modification of GABAergic systems. [This work was supported by the Korea Research Foundation Grant funded by the Korean Government (MOEHRD) (The Regional Research Universities Program/Center for Healthcare Technology Development)].

• Journal of the Korean housing association
• /
• v.18 no.5
• /
• pp.1-10
• /
• 2007

This study is to analyze the residential spatial composition structures of vernacular agricultural village which to be called Wanggok in Yeongdong area. The results of this study are as follows; ${\cdot}$ The backyard of farmhouses is surrounded by a fence and a frontyard is open to the road, so that the spatial realm system from the road to the backyard is classified as public-semi public-private realm. ${\cdot}$ The plan type of this village is mainly composed of ㅡ type Gyeobjib (the two row rooms under one roof) and ㄱ type Gyeobjib, the Anmaru (the inner wood floor to be surrounded with wall) in both of which plays an important role that connects Sarangbang (the men's main room) with Anbang (the women's main room) in the residential space. ${\cdot}$ The particular item that not found out in another area is the Sarangbang kitchen which located to Sarangbang's side wall to be furnished with a fire hole. ${\cdot}$ The houses represent the socio-cultural environmental elements of those built days, such as while Sarangbang is faced on a frontyard to be open to the neighborhood, Anbang is faced on a backyard surrounded with a fence to be closed to the one. ${\cdot}$ The Gyeobjib with Anmaru appeared by cultural transformation connecting the 田-shaped house of Hamgyeongdo with the Gyeobjib with Anmaru of Gangwondo and Gyeongsangbukdo. ${\cdot}$ The ㄱ type Gyeobjib is preferred to ㅡ type Gyeobjib because of the sea wind and the north-east wind occurring by geographical and climatic environment elements, the privacy protection according to look into a frontyard, the muck drainage of cowshed to make use of ground unevenness, the economic gains called material saving and the intention to enlarge the frontyard as to be concentrated in a residential space and etc.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.18 no.10
• /
• pp.2443-2450
• /
• 2014

In the motion recognition system using depth image, the depth image is converted to the real world formed 3D point cloud data for efficient algorithm apply. And then, output depth image is converted by the projective world after algorithm apply. However, when coordinate conversion, rounding error and data loss by applied algorithm are occurred. In this paper, when convert 3D point cloud data to depth image, we proposed efficient conversion method and its hardware implementation without rounding error and data loss according image size change. The proposed system make progress using the OpenCV and the window program, and we test a system using the Kinect in real time. In addition, designed using Verilog-HDL and verified through the Zynq-7000 FPGA Board of Xilinx.

• Current Photovoltaic Research
• /
• v.9 no.3
• /
• pp.84-95
• /
• 2021

The power conversion efficiency of Cu₂ZnSnSe₄ (CZTSe) solar cells depends on the absorber layer thickness; however, changes in the characteristics of the cells with varying absorber layer thickness are unclear. In this study, we investigated the changes in the characteristics of CZTSe solar cells for varying absorber layer thickness. Five absorber thicknesses were employed: CZTSe1 2.78 ㎛, CZTSe2 1.01 ㎛, CZTSe3 0.55 ㎛, CZTSe4 0.29 ㎛, and CZTSe5 0.15-0.23 ㎛. The efficiency of the CZTSe solar cells decreased as the absorber thickness decreased, resulting in power conversion efficiencies of 10.45% (CZTSe1), 8.67% (CZTSe2), 7.14% (CZTSe3), 3.44% (CZTSe4), and 1.54% (CZTSe5). As the thickness of the CZTSe absorber layer decreased, the electron-hole recombination at the grain boundaries and the absorber-back-contact interface increased. This caused an increase in the current loss, owing to light loss in the long-wavelength region. In addition, as the thickness of the CZTSe absorber layer decreased, more ZnSe was produced, and the resulting defects and defect clusters led to an open-circuit voltage loss.

• Water Engineering Research
• /
• v.2 no.2
• /
• pp.123-138
• /
• 2001

An injection experiment was carried ut to investigate the pressure domain within which hydromechanical coupling influences considerably the hydrologic behavior of a granite rock mass. The resulting database is used for testing a numerical model dedicated to the analysis of such hydromechanical interactions. These measurements were performed in an open hole section, isolated from shallower zones by a packer set at a depth of 275 m and extending down to 840 m. They consisted in a series of flow meter injection tests, at increasing injection rates. Field results showed that conductive fractures from a dynamic and interdependent network, that individual fracture zones could not be adequately modeled as independent systems, that new fluid intakes zones appeared when pore pressure exceeded the minimum principal stress magnitude in that well, and that pore pressures much larger than this minimum stress could be further supported by the circulated fractures. These characteristics give rise to the question of the influence of the morphology of the natural fracture network in a rock mass under anisotropic stress conditions on the effects of hydromechanical couplings.

• Bulletin of the Korean Chemical Society
• /
• v.32 no.spc8
• /
• pp.3031-3038
• /
• 2011

Ion-coordinating ruthenium complexes [cis-Ru(dcbpy)(L)(NCS)$_2$, where dcbpy is 4,4'-dicarboxylic acid-2,2'-bipyridine and L is 1,4,7,10-tetraoxa-13-azacyclopentadecane, JK-121, or bis(2-(2-methoxy-ethoxy)ethyl) amine, JK-122] have been synthesized and characterized using $^1H$ NMR, Fourier transform IR, UV/vis spectroscopy, and cyclic voltammetry. The effect of $Li^+$ in the electrolyte on the photovoltaic performance was investigated. With the stepwise addition of $Li^+$ to a liquid electrolyte, the device shows significant increase in the photo-current density, but a small decrease in the open circuit voltage. The solar cell with a hole conductor, the addition of $Li^+$ resulted in a 30% improvement in efficiency. The JK-121 sensitized cells in the liquid and solid-state electrolyte give power conversion efficiencies of 6.95% and 2.59%, respectively, under the simulated sunlight.

• International Journal of Naval Architecture and Ocean Engineering
• /
• v.10 no.5
• /
• pp.629-643
• /
• 2018

For a sailing ship, the frictional resistance exerted on the hull of ship is due to viscous effect of the fluid flow, which is proportional to the wetted area of the hull and moving speed of ship. This resistance can be reduced through air bubble lubrication to the hull. The traditional way of introducing air to the wetted hull consumes extra energy to retain stability of air layer or bubbles. It leads to lower reduction rate of the net frictional resistance. In the present paper, a novel air bubble lubrication technique proposed by Kumagai et al. (2014), the Winged Air Induction Pipe (WAIP) device with opening hole on the upper surface of the hydrofoil is numerically investigated. This device is able to naturally introduce air to be sandwiched between the wetted hull and water. Propulsion system efficiency can be therefore increased by employing the WAIP device to reduce frictional drag. In order to maximize the device performance and explore the underlying physics, parametric study is carried out numerically. Effects of submerged depth of the hydrofoil and properties of the opening holes on the upper surface of the hydrofoil are investigated. The results show that more holes are favourable to reduce frictional drag. 62.85% can be achieved by applying 4 number of holes.

• Journal of Trauma and Injury
• /
• v.29 no.1
• /
• pp.22-27
• /
• 2016

Purpose: The optimal method of fixation of symphysis pubis (SP) diastasis in pelvic ring injuries is still controversial. In this study, we investigated the radiological and the clinical results of a precontoured 4.5-mm symphysis pubis (SP) plate with tension band wiring (TBW) after an anterior pelvic injury in pelvic fractures. Methods: We treated 25 patients with traumatic SP diastasis by open reduction and internal fixation with plates and wires. We used a four-hole 4.5-mm precontoured SP plate with a tension band wiring. Results: Patients with a SP with TBW fixation achieved excellent or good results at final follow-up. Post-operative complications included two (8%) patients with metal work movement. The mean symphyseal width was smaller in 4.5 mm SP plate with TBW during 1-year follow up period. Conclusion: A precontoured symphysis pubis plate (4.5 mm) with figure-of-eight fashion tension band wiring shows favorable radiological results, excellent or good clinical outcome, and a lower complication (hardware failure and revision surgery).

• Journal of Korean Society of Water and Wastewater
• /
• v.28 no.2
• /
• pp.217-223
• /
• 2014

In order to suggest the methodology for improving the equity of flow distribution in open channel with multiple outlet, CFD simulations were carried out for actual scale distribution channel being operated in domestic G_WTP(Water Treatment Plant). Also, before and after installing the longitudinal multi hole(diameter=250 mm, 116 holes) baffle suggested by this research, turbidity measurements data were collected for evaluating the effects of hydraulic modification for inlet flow equity. From the both results, total turbidity of settled water was lowered by 30 % and equity of flow distribution was improved about 60 % compared with before hydraulic structure modification.

• Journal of the Korean Society for Precision Engineering
• /
• v.21 no.12
• /
• pp.92-99
• /
• 2004

The formation degree of sustain (ITO pattern) decides quality of PDP (Plasma Display Panel). For this reason, it makes efforts in searching defects more than 30 un as 100%. Now, the existing inspection is dependent upon naked eye or microscope in off-line PDP manufacturing process. In this study developed prototype inspection system of PDP 170 glass is based on line-scan mechanism. Developed system creates information that detects and sorts kinds of defect automatically. Designed inspection technology adopts multi-vision method by slip-beam formation for the minimum of inspection time and detection algorithm is embodied in detection ability of developed system. Designed algorithm had to make good use of kernel matrix that draws up an approach to geometry. A characteristic of defects, as pin hole, substance, protrusion, are extracted from blob analysis method. Defects, as open, short, spots and et al, are distinguished by line type inspection algorithm. In experiment, we could have ensured ability of inspection that can be detected with reliability of up to 95% in about 60 seconds.