• Journal of the Korean Home Economics Association
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• v.44 no.2 s.216
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• pp.137-152
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• 2006

The major purpose of this study was to investigate the causal effect of the primary triad experiences on dating relationship satisfaction through self-esteem among college students. The primary triad experiences were composed of the parents' differentiation level of couple relationship and the parent-child relationship including family rule, triangulation and communication. Dating relationship satisfaction included such subscales as problem-solving communication, global satisfaction, affection communication and time together. The study data were collected from 382 college students by using self-administered questionnaire method. The results showed that parents' differentiation was positively correlated with self-esteem and all components of dating relationship satisfaction and that family rule was negatively associated only with problem-solving communication. Triangulation was negatively related with most components of dating relationship satisfaction and self-esteem, while parent-child communication showed positive correlations with the same variables. Path analysis results showed that self-esteem mediated the effect of most variables of primary triad experiences on dating relationship satisfaction. In addition, variables of the primary triad experience had direct influences on most components of dating relationship satisfaction. Self-esteem was found to be the most powerful variable influencing dating relationship satisfaction. The findings of the study were discussed in terms of pre-marital education and counseling.

• Journal of Korean Medical classics
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• v.20 no.4
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• pp.119-126
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• 2007

The biological and pathological states of lung, spleen, liver and kidneys are determined by nature and emotion of sorrow, anger, joy and pleasure, It is considered that the music, besides medicine or acupuncture, can be a way of treating as a therapeutics for the treatment of Sasangin's diseases. This study is to find out a way of music therapy for the treatment of Sasangin's diseases. The ways of music therapy in each constitution based on 'the great and small of Viscera and Bowels' and 'the exhale and inhale, the drawing in and sending out' are as follows: 1. In case of Soeumin, a skip going up melodic progression, dotted rhythm and the major triad harmonic progression are recommended to improve the Qi of warm Yang. 2. In case of Soyangin, in regular sequence down melodic progression, a sixteenth note and the minor triad harmonic progression are recommended to improve the Qi of cool Yin. 3. In case of Taeumin, in regular sequence going up melodic progression, a sixteenth note and the bright and active the major triad harmonic progression are recommended to improve the Qi of dispersing exhale. 4. In case of Taeyangin, a skip down melodic progression, a quarter note and a diminished triad harmonic progression are recommended to improve the Qi of gathering inhale.

• Communications of Mathematical Education
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• v.28 no.2
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• pp.219-234
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• 2014

Music and mathematics have a lot of structural similarities. Major and minor triads used importantly in music are in a relationship of inversion in which the sequence of the intervals is reversed, which is equivalent to reflection in mathematics. Geometrical expressions help understand structures in music as well as mathematics, and a diagram that shows tonal relationships in music is called Tonnetz. Relationships of reflection between major and minor triads can easily be understood by using Tonnetz, and also, transpositions can be expressed in translation. This study looks into existing Tonnetz and introduces S-Tonnetz newly formed by a mathematical principle.

• Molecules and Cells
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• v.42 no.1
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• pp.56-66
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• 2019

Histidine triad nucleotide-binding protein (HINT) is a member of the histidine triad (HIT) superfamily, which has hydrolase activity owing to a histidine triad motif. The HIT superfamily can be divided to five classes with functions in galactose metabolism, DNA repair, and tumor suppression. HINTs are highly conserved from archaea to humans and function as tumor suppressors, translation regulators, and neuropathy inhibitors. Although the structures of HINT proteins from various species have been reported, limited structural information is available for fungal species. Here, to elucidate the structural features and functional diversity of HINTs, we determined the crystal structure of HINT from the pathogenic fungus Candida albicans (CaHINT) in complex with zinc ions at a resolution of $2.5{\AA}$. Based on structural comparisons, the monomer of CaHINT overlaid best with HINT protein from the protozoal species Leishmania major. Additionally, structural comparisons with human HINT revealed an additional helix at the C-terminus of CaHINT. Interestingly, the extended C-terminal helix interacted with the N-terminal loop (${\alpha}1-{\beta}1$) and with the ${\alpha}3$ helix, which appeared to stabilize the dimerization of CaHINT. In the C-terminal region, structural and sequence comparisons showed strong relationships among 19 diverse species from archea to humans, suggesting early separation in the course of evolution. Further studies are required to address the functional significance of variations in the C-terminal region. This structural analysis of CaHINT provided important insights into the molecular aspects of evolution within the HIT superfamily.

• Journal of fish pathology
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• v.32 no.2
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• pp.49-57
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• 2019

In this study, we collected 39 megalocytiviruses isolated from diseased fish in Korea from 2012 to 2018. Major capsid protein (MCP) gene, a part of vascular endothelial growth factor (VEGF) gene and histidine triad motif-like protein (HIT) genes of Megalocytivirus were targeted for PCR amplification and analysis of those DNA nucleotide sequences. Korean strains revealed two genotypes (red sea bream iridovirus and turbot reddish body iridovirus types) based on the phylogeny of MCP gene. The red sea bream iridovirus type (RSIV-type) megalocytiviruses were divided into RSIV-subgroup 1 and 2. From the phylogenetic analysis of the VEGF genes, a genotypic variant of RSIV-type Megalocytivirus was identified. The HIT-like protein gene was detected in RSIVs, but not in TBRIV and ISKNV, suggesting that HIT-like protein gene may be specific in RSIV.

• The Journal of the Petrological Society of Korea
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• v.17 no.2
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• pp.95-107
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• 2008

The Carved Buddhist Triad on Rock-cliff in Sinarnri (Treasure No. 680) consists of biotite granodiorite, which were positively carved on fore and west planes of four subvertical cliffs by two joint sets of NE-SW and NNW-SSE directions. The cliffs are $N50^{\circ}E\;85^{\circ}SE$ in fore plane, $N25^{\circ}W\;90^{\circ}$ in west plane, $N40{\sim}50^{\circ}E\; 82{\sim}85^{\circ}NW$, back plane, $N20^{\circ}W\;75^{\circ}SW$ in east plane, which are parallel to two joint sets of NE-SW and NNW-SSE directions in geology around it. The chemical index of alteration ranges 60.3 to 62.0 from the major elements in the rock that was weathered into producing kaolin minerals from alteration of feldspars and biotite. The Buddhist image has been deteriorated into joints, brown rusts, discolorations and granular disintegrations by such deterioration causes as deformation, moisture, temperature variation and microorganic living. The moisture, which leaks from groundwater in the rock, dissolve to decompose minerals.

• Journal of the Economic Geographical Society of Korea
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• v.9 no.2
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• pp.225-242
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• 2006

This study aims to analyze the spatial distribution pattern of international trade. The method is to analyze the principal components by changing interaction attribute matrix of four dimensions (hinterland, gateway, foreland and commodities) into two dimension matrix. The study area is the territory region of Cheongju clearance depot in inland. The result are as follows : Major spatial patterns of regional connections by hinterland, gateway and foreland are, in the case of exports, ten patterns and in the case of imports come to nine. Composition of major export and import commodities in Cheongju clearance depot are similar, but precision instrument manufactured commodity and nonmetal mineral are remarkable in export and mineral manufactured commodity machinery and electronic manufactured commodity are remarkable in import. Gateway are similar to export and import, but Incheon international airport is used more in the case of import. And Cheongiu international airport is used for some commodities and is remarkable as a foreland of import for the areas outside of Chungcheongbuk-do.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.28 no.1
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• pp.43-47
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• 2017

Laryngopharyngeal reflux disease (LPRD) is common in laryngologic practice. In Korea, up to 1 out of every 5 patients who visit otorhinolaryngology clinic is supposed to have LPRD with symptoms and physical findings. Major symptoms of LPRD include hoarseness, cough, reflux symptom and mild dysphagia. Even though LPRD is common, its diagnosis may be difficult, because its symptoms are nonspecific and the laryngeal findings are not always associated with symptom severity. In Recent study, 66.4% of Patient who has LPRD also associated with esophageal motility disorders. Esophageal achalasia is a disease of unknown etiology characterized by an absence of peristalsis in the body of esophagus and nonrelaxing hypertension of the lower esophageal sphincter. Common cause is loss of ganglion cells in Auerbachs plexus. The classic triad of symptoms in achalasia includes dysphagia, regurgitation and weight loss. LPRD and esophageal achalasia have similar symptoms but have different treatment of choice. The Differentiation diagnosis of theses disease is important and should be established by history, radiologic examination and endoscopic examination. We recently assessed a 59-year-old female patient who complained of an epigastric pain, dysphagia and chronic cough. LPRD was initially diagnosed on Laryngoscopic examination and Reflux Symptom Index, but patient was not relieved of any symptoms after treatment of Proton Pump Inhibitor for 3 months. After high resolution manometry, esophageal achalasia was finally diagnosed. We report this case regarding the diagnosis and treatment with review of literatures because we have to think about esophageal motility disorders as a differential diagnosis in laryngology.

• Bulletin of the Korean Chemical Society
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• v.28 no.8
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• pp.1335-1340
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• 2007

β-Ketoacyl acyl carrier protein synthase (KAS) III is a particularly attractive target in the type II fatty acid synthetic pathway, since it is central to the initiation of fatty acid synthesis. Enterococcus faecalis, a Grampositive bacterium, is one of the major causes of hospital acquired infections. The rise of multidrug-resistant of most bacteria requires the development of new antibiotics, such as inhibition of the KAS III. In order to block the fatty acid synthesis by inhibition of KAS III, at first, three dimensional structure of Enterococcus faecalis KAS III (efKAS III) was determined by comparative homology modeling using MODELLER based on x-ray structure of Staphylococcus aureus KAS III (saKAS III) which is a gram-positive bacteria and is 36.1% identical in amino acid sequences with efKAS III. Since His-Asn-Cys catalytic triad is conserved in efKAS III and saKAS III, substrate specificity of efKAS III and saKAS III and the size of primer binding pocket of these two proteins are expected to be similar. Ligand docking study of efKAS III with naringenin and apigenin showed that naringenin docked more strongly with efKAS III than apigenin, resulting in the intensive hydrogen bond network between naringenin and efKAS III. Also, only naringenin showed antibacterial activity against E. faecalis at 256 μg/mL. This study may give practical implications of flavonoids for antimicrobial effects against E. faecalis.

• Journal of Korean Philosophical Society
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• v.105
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• pp.401-421
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• 2008

The purpose of this paper is to examine the achieved role of Kant philosophy in restructuring Deleuze philosophy from either a positive or effective perspectives. On top of this foundation, I will demonstrate the major part largely unknown in a composing structural elements of Deleuze philosophy as follows: 1. I will draw a bird's-eye view of the triad of Bergson, Nietsche, and Spinoza regarding Deleuze philosophy. Especially I will spare time in analyzing Deleuze's late works like and then demonstrate the structure of Deleuze movie philosophy. 2. The line of Kant's position in that circumstance will be clarified as well. 3. Through that, the meaning of Kantian attempt and its effect will be examined. Finally the connecting Kant with various levels of Deleuze's Copernicusian revolutions based on will certainly bring about a meaningful fruitification.