• Journal of Korean Elementary Science Education
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• v.32 no.4
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• pp.593-606
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• 2013

The purpose of this study was to examine the effect of science-based STEAM program using a portfolio on elementary students' formation of science concepts and investigate students' opinion about the program. The developed program was applied to 1 experimental class(10 boys and 12 girls) and general science lessons, using a science textbook, was applied to 1 controlled class(11 boys and 13 girls) of $5^{th}$ grade students at S elementary school in Seoul through a total 6 sessions. Concept tests of the solar system were conducted before and after lessons and analysis of covariance was conducted. The results of this study were as follows. First, science-based STEAM program using a portfolio was effective to form science concepts. Second, students opinion about science-based STEAM program using a portfolio was positive. Students think the program was effective in understanding science contents, promoting thinking, self-motivation. It is expected that this study will be basic material to expand STEAM in science education.

• Journal of Practical Engineering Education
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• v.14 no.3
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• pp.471-477
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• 2022

In this study, an educational program was developed that allows students who take data science courses in the high school credit system to explore related fields after learning data science education. Accordingly, the existing research and requirements for data science education were analyzed, a learning plan was designed, and an educational program was developed in accordance with a step-by-step educational program. In addition, since there is no research on data science education for the high school credit system in existing studies, the research was conducted in the stages of problem definition, data collection, data preprocessing, data analysis, data visualization, and simulation, and referred to studies on data science education that have been conducted in existing schools. Through this study, it is expected that research on data science education in the high school credit system will become more active.

• Journal of the Korean Society of Earth Science Education
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• v.11 no.3
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• pp.182-192
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• 2018

The purpose of this study was to examine the effects of school forest activities program on elementary students' science process skill and attitude toward science to make suggestions to help develop and extend the program. The subjects of the study were 49 students of two classes. One class of 24 students, experimental class, took developed 10 periods of school forest activities program. While the other class of 25 students, comparative class, took ordinary teacher driven periods using photo materials and study papers. Before and after the program, pre and post test were done. The results of this study can be summarized as follows: First, the school forest activities program didn't have a meaningful effect on students' science process skill. Second, the school forest activities program had a meaningful effect on the improvement of students' attitude toward science. From the interview with experimental class, we could know that students had a favorable impression and high satisfaction level about the activities program.

• Reproductive and Developmental Biology
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• v.35 no.2
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• pp.159-165
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• 2011

To explore the role of histone deactylase (HDAC) activation in an in vivo model of hypertrophy, we studied the effects of Trichostatin A (TSA). TSA subjected to thoracic aortic banding (TAB)-induced pressure stress in mice. In histological observations, TAB in treated mice showed a significant hypertrophic response, whereas the sham operation remained nearly normal structure with partially blunted hypertrophy. TSA treatment had no effect (measured as HW/BW) on sham-operated animals. TAB animals treated with vehicle manifested a robust ~50% hypertrophic response (p<0.05 vs sham). TAB mice treated with 2 mg/kg/day TSA manifested a blunted growth responses, which was significantly diminished (p<0.05) compared with vehicle-treated TAB mice. TAB mice treated with a lower dose of TSA (0.5 mg/kg/day) manifested a similar blunting of hypertrophic growth (~25% increase in heart mass). Furthermore, to determine activity duration of TSA in vitro, 1 nM TSA was added to H9c2 cells. Histone acetylation was initiated at 4 hr after treatment, and it was peak up to 18 hr, then followed by significantly reduced to 30 hr. We also analyzed the expression of p53 following TSA treatment, wherein p53 expression was elevated at 4 hr, and it was maintained to 24 hr after treatment. ERK was activated at 8 hr, and maintained till 30 hr after treatment suggesting an intracellular signaling interaction between TSA and p53 expression Taken together, it is suggested that HDAC activation is required for pressure-overload growth of the heart. Eventually, these data suggest that histone acetylation may be a novel target for therapeutic intervention in pressure-overloaded cardiac hypertrophy.

• Journal of the Korean Society of Physical Medicine
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• v.6 no.4
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• pp.455-464
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• 2011

Purpose : This study is to investigate difference in the isometric muscular function of knee joints according to the time of participation in rehabilitation exercise in patients who had anterior cruciate ligament reconstruction. Methods : The subjects of this study were patients by sports injury or accident in the sports rehabilitation center of G hospital. The early exercise program group (n=7) started functional ability exercise from 2 weeks after the surgery and the late exercise program group (n=7) from 6 weeks after the surgery. Statistical analysis was used repeated measure ANOVA to test mean difference by using SPSS 18.0 for windows. Results : First, as to quadriceps femoris muscle according to the time of participation in exercise program, significant difference was observed according to interaction and time. Second, as to hamstring muscle according to the time of participation in exercise program, significant difference was observed in muscle strength according to time. Conclusion : This results suggest that if the effect of exercise program is similar between the early starting group and the late starting group, it is not necessary to have a long period of fixation as in the late exercise program group but is desirable to start functional ability exercise early in order to relieve pains in the knee joints.

• Food Science and Biotechnology
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• v.17 no.6
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• pp.1372-1375
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• 2008

The aprE2 gene from Bacillus subtilis CH3-5 was expressed in Bacillus licheniformis ATCC 10716 using a Bacillus-Escherichai coli shuttle vector, pHY300PLK. The fibrinolytic activity of transformant (TF) increased significantly compared to B. licheniformis 10716 control cell. During the 100 hr incubation in Luria-Bertaini broth at $37^{\circ}C$, fibrinolytic activity of B. licheniformis TF increased rapidly at the late growth stage, after 52 hr of incubation, which was confirmed by zymography using a fibrin gel. pHY3-5 was stably maintained in B. licheniformis without tetracycline (Tc) in the media, 60.9% of cells still maintained pHY3-5 after 100 hr of cultivation.

• Journal of Gifted/Talented Education
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• v.26 no.3
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• pp.449-471
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• 2016

This study was conducted in order to investigate how a Problem-Based Learning (PBL) program titled(called) 'Designing Safe and Strong Bridge' effects scientifically gifted students' scientific attitude, scientific career orientation and leadership. The participants were 19 scientifically gifted students in the second grade in C high school in Gyeonggi province; they were selected by participation in the tri-level gifted students identification step. Before and after 14 units of the program, the participants were asked to take tests about scientific attitude, scientific career orientation and leadership and to write a review about the PBL program at the end. The major results of this study are as follows. First, participants' scientific attitude was statistically significantly improved after the PBL program (p<.05). In the sub-domain of this area, six parts excluding the part of openness were significantly developed. Second, the degree of scientific career orientation was statistically significantly improved after the PBL program (p<.05). All 4 sub-domains in the degree of scientific career were significantly developed. Third, all of leadership scores were statistically significantly increased after the PBL program (p<.05). In the first factor, the parts of inner and inter personal characteristics were significantly developed. According to their post-program opinions, participants developed in terms of all the secondary factors, such as ability of interpersonal relation, consideration for others and groups, responsibility for the task, confidence and vision, during the process of PBL problem-solving in the small group work.

• The Journal of Korean Academic Society of Nursing Education
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• v.20 no.3
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• pp.372-381
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• 2014

Purpose: This study aims to investigate the effects of a peer gatekeeper training program on existential spiritual well-being, interpersonal relationship with friends, and suicide probability for middle school students. Methods: The participants were fifty students who were at a vocational middle school in D city from october 13, 2012 to november 10, 2012. To test the effects of the peer gatekeeper training program, the participants were divided into two groups in the way of matching distribution, an experimental group(24) and a control group(26). Data were analyzed by Chi-square test, t-test, and Fisher exact probability test using the SPSS/WIN 12.0 program. Results: After attending the peer gatekeeper training program, significant differences between the experimental group and the control group were found in existential spiritual well-being(t=2.80, p=.007) and interpersonal relationship with friends scores(t=2.67, p=.010). However, there was no statistically significant difference in suicide probability between the two groups. Conclusion: The results indicate that the peer gatekeeper training program enhance existential spiritual well-being and interpersonal relationship with friends of middle school students. Therefore, this program could be a good strategy that teachers and community mental health nurses can use for suicide prevention of middle school students.

• Journal of Korean Academy of Nursing
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• v.26 no.4
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• pp.799-807
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• 1996

This study was done to compare the effects of managing obesity using a behavior modification program and an aerobic exercise in adolescent girls. Thirty three subjects were selected from one girls' middle school located in Seoul. Seventeen girls participated in the behavior modification program by joining 60-90 minute group sessions weekly. The aerobic exercise program was given to 16 girls three times per week for 60 minutes each. These iterventions continued for eight weeks from October 17 to December 10, 1995. The data were obtained before and after the interventions by measuring degree of obesity, body weight, blood pressure, serum lipid, %body fat, and waist to hip ratio(WHR). Data ware analysed by using paired t-test. The results are as follows. 1. Subjects in both the behavior modification and the aerobic exercise groups showed significant decrese in the degree of obesity, body weight, diastolic blood pressure, total cholesterol, low density lipoprotein, %body fat and fat mass after the 8-week interventions. 2. Systolic bood pressure, high density lipoprotein cholesterol and waist to hip ratio were significantly decreased after the 8-week intervention in the behavior modification program group while triglyceride was significantly decreased after the 8-week intervention in the aerobic exercise program group. These findings indicate that both behavior modification and aerobic exercise programs are good strategies for managing obesity among adolescent girls.

• Physical Therapy Rehabilitation Science
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• v.10 no.4
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• pp.430-437
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• 2021

Objective: The purpose of this study was to investigate the effect of 3-dimensional posture correction(3DPC) exercise program incorporating PNF respiratory muscle strengthening(RMS) exercise on spinal alignment and trunk expansion in patients with idiopathic scoliosis and the difference in intervention effect by type of idiopathic scoliosis. Design: Comparative study using paired t-test and analysis of variance measures. Methods: The subjects of this study were 5 men and 24 women diagnosed with idiopathic scoliosis with a Cobb angle greater than 10 degrees and less than 45 degrees. A 3DPC exercise program incorporating PNF RMS exercise was conducted twice a week for 1 hour per session for 6 weeks, and Cobb angle, Angle of trunk rotation, and trunk expansion were measured before and after the intervention. Results: After the intervention, Cobb angle and trunk rotation angle showed a statistically significant decrease, and trunk expansion showed a statistically significant increase. In the effect difference by type, there was a statistically significant difference in the angle of trunk rotation of the thoracic in 3C and Single Lumbar. Conclusions: In conclusion, it is thought that a 3DPC exercise program incorporating PNF RMS exercise can be effectively used in clinical practice to improve spinal alignment and trunk expansion in patients with idiopathic scoliosis.