• Interdisciplinary Bio Central
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• v.4 no.3
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• pp.10.1-10.12
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• 2012

Introduction: We investigated frameshift suppressor tRNAs previously reported to use five-base anticodon-codon interactions in order to provide a collection of frameshift suppressor tRNAs to the synthetic biology community and to develop modular frameshift suppressor logic devices for use in synthetic biology applications. Results and Discussion: We adapted eleven previously described frameshift suppressor tRNAs to the BioBrick cloning format, and built three genetic logic circuits to detect frameshift suppression. The three circuits employed three different mechanisms: direct frameshift suppression of reporter gene mutations, frameshift suppression leading to positive feedback via quorum sensing, and enzymatic amplification of frameshift suppression signals. In the course of testing frameshift suppressor logic, we uncovered unexpected behavior in the frameshift suppressor tRNAs. The results led us to posit a four-base binding hypothesis for the frameshift suppressor tRNA interactions with mRNA as an alternative to the published five-base binding model. Conclusion and Prospects: The published five-base anticodon/codon rule explained only 17 of the 58 frameshift suppression experiments we conducted. Our deduced four-base binding rule successfully explained 56 out of our 58 frameshift suppression results. In the process of applying biological knowledge about frameshift suppressor tRNAs to the engineering application of frameshift suppressor logic, we discovered new biological knowledge. This knowledge leads to a redesign of the original engineering application and encourages new ones. Our study reinforces the concept that synthetic biology is often a winding path from science to engineering and back again; scientific investigations spark engineering applications, the implementation of which suggests new scientific investigations.

• The Journal of the Korea Contents Association
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• v.21 no.6
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• pp.392-403
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• 2021

The purpose of this study was to examine the effect of emotion regulation strategy on posttraumatic growth and to confirm serial multiple mediating effects of self disclosure on a traumatic experience and social support in relationship between suppression strategy of emotional expression and posttraumatic growth. A survey was conducted for adults over the age of 18. Data of 663 adults (222 men, 441 women) were analyzed. According to analysis by using SPSS Process Macro, the less suppression strategy of emotional expression was used, the higher posttraumatic growth was. Simple mediating effect of self disclosure was confirmed between suppression strategy of emotional expression and posttraumatic growth. Serial multiple mediating effects of self disclosure and social support were shown in relationship between suppression strategy of emotional expression and posttraumatic growth. It means that the more people who use less suppression of emotional expression as their emotion regulation strategy, the more they disclose on their traumatic experience, then, they will receive emotional comfort and support from the people around, finally reaching posttraumatic growth. The importance of self disclosure and social support on posttraumatic growth was verified. Counseling intervention method was suggested for involuntary clients who usually suppress emotional expression, to enhance their posttraumatic growth. Lastly, significance and limitations of this study were suggested for follow-up studies.

• The Journal of the Convergence on Culture Technology
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• v.10 no.3
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• pp.165-172
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• 2024

This study illuminates the relationship between childhood abuse experiences and early maladaptive schemas, and compares the moderating effects of expressive suppression and cognitive reappraisal within this relationship. Conducting a self-report survey among 220 graduate students in Daejeon and Chungcheong regions, data from 210 participants were analyzed. The results notably revealed that the interaction effect of suppression, but not cognitive reappraisal, significantly moderates the relationship between childhood abuse experiences and disconnection/rejection schemas. Specifically, high levels of expressive suppression were associated with a decrease in the negative impact of childhood abuse on disconnection/rejection schemas, whereas low levels of suppression increased this negative impact. This suggests that for individuals with long-standing early maladaptive schemas, which have solidified over time akin to personality traits, cognitive reappraisal strategies may be less effective in inducing change. Conversely, expressive suppression strategies may more effectively reduce the intensity of disconnection/rejection schemas, among other early maladaptive schemas. These findings provide important implications for understanding the long-term effects of childhood abuse and developing intervention strategies to mitigate its resultant maladaptive schemas. Based on the outcomes of this study, suggestions for future research are discussed, along with the potential applicability and limitations of suppression and reappraisal strategies in psychological interventions.

• Proceedings of the KSME Conference
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• 2007.05b
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• pp.2983-2988
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• 2007

In the present study, the numerical investigation on the effects of water-mist characteristics has been carried out for the fire suppression mechanism. The FDS are used to simulate the interaction of fire plume and water mists, and program describes the fire-driven flows using LES turbulence model, the mixture fraction combustion model, the finite volume method of radiation transport for a non-scattering gray gas, and conjugate heat transfer between wall and gas flow. The numerical model is consisted of a rectangular enclosure of $L{\times}W{\times}H=1.5{\times}1.5{\times}2.0m$ and a water mist nozzle that be installed 1.8m from fire pool. In the study, the parameters of nozzle for simulation are the droplet size and the spray velocity. Finally, the droplet size influences to fire flume on fire suppression than spray velocity because of the effect of terminal velocity, and the optimal condition for fire suppression is that the droplet size and the spray velocity are $100{\mu}m$ and 20m/s, respectively.

• Journal of Distribution Science
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• v.13 no.9
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• pp.13-18
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• 2015

Purpose - This study investigates the effects of thought suppression on depression and uneasiness among college students likely to be influenced by smart phone addiction. Research design, data, and methodology - A total of 151 valid questionnaires were collected. The following analyses were conducted using SPSS 19.0 and AMOS 19.0: frequency, descriptive statistics, correlation, simple regression, and multiple regression. Results - Smart phone addiction increased uneasiness, depression, impulsiveness, and aggression. Moreover, uneasiness, depression, impulsiveness and aggression from smart phone addiction, had a negative influence on psychological wellbeing resulting in potential delinquent behavior. In addition, the addiction treatment relied heavily on drugs; therefore, such psychological treatment should be strengthened to control intermittent addiction. Conclusions - The results indicate that various kinds of research are needed to investigate personality and environmental factors that influence smart phone addiction. Additionally, studies on lessening smart phone addiction and living healthy lifestyles are needed. Moreover, psychological rehabilitation and treatment should be developed to lessen the rebound effect after thought suppression, to verify the effects of clinical application, and to prevent intermittent addiction.

• IEIE Transactions on Smart Processing and Computing
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• v.6 no.2
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• pp.117-123
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• 2017

N-continuous orthogonal frequency division multiplexing (OFDM) is a precoding method for sidelobe suppression of OFDM signals and seamlessly connects OFDM symbols up to the high-order derivative for sidelobe suppression, which is suitable for suppressing out-of-band radiation. However, it severely degrades the error rate as it increases the continuous derivative order. Two schemes for orthogonal precoding of N-continuous OFDM have been proposed to achieve an ideal error rate while maintaining sidelobe suppression performance; however, the large size of the precoder matrices in both schemes causes very high computational complexity for precoding and decoding. This paper proposes matrix decomposition of precoder matrices with a large size in the orthogonal precoding schemes in order to reduce computational complexity. Numerical experiments show that the proposed method can drastically reduce computational complexity without any performance degradation.

• Journal of Mechanical Science and Technology
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• v.16 no.12
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• pp.1583-1593
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• 2002

This paper discusses the model validation and vibration suppression of an AMB flexible rotor via additional LQG controller. The main difficulty in the vibration suppression of the flexible rotor using AMB is to realize a controller that can minimize resonance without injuring the stabilized rigid modes. In order to solve this problem, simple scheme for system modeling and controller design are developed. Firstly, the AMB flexible rotor is stabilized with a PID controller, which leads to a new stable rotor-bearing system. Then, authors propose the model validation procedure using measured open-loop frequency responses to obtain an accurate model of the AMB flexible rotor system. After that, LQG controller with modal weighting is designed to suppress resonances of the stable rotor-bearing system. Due to the poor controllability and observability of flexible modes compared to rigid ones, balancing of two Gramians is prerequisite for the fair LQG controller design. Simulation with step disturbance and experimental results of unbalance response up to 10,000 rpm verified the effectiveness of the proposed scheme.

• Korean Journal of Digital Imaging in Medicine
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• v.14 no.1
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• pp.31-35
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• 2012

To test the real image quality of a spectral attenuated inversion-recovery (SPAIR) fat-suppression (FS) techniquein clinical abdominal MRI by comparison to turbo spin echo inversion-recovery (TSEIR) fat-suppression (FS) technique. 3.0T MRI studies of the abdomen were performed in 30 patients with liver lesions (hemangiomas n: 15; HCC n: 15). T2W sequences were acquired using SPAIR TSEIR. Measurements included retroperitoneal and mesenteric fat signal-to-noise (SNR) to evaluate FS; liver lesion contrast-to-noise (CNR) to evaluate bulk water signal recovery effects; and bowel wall delineation to evaluate susceptibility and physiological motion effects. SPAIR-TSEIR images produce significantly improved FS and liver lesion CNR. The mean SNR of the retroperitoneal and mesenteric fat for SPAIR were 20.5, 10.2 and TSEIR were 43.2, 24.1 (P<0.05). SPAIR-TSEIR images produced higher CNR for both hemangiomas CNR 164.88 vs 126.83 (P<0.05) and metastasis CNR 75.27 vs 53.19 (P<0.05). Bowel wall visualization was significantly improved using in both SPAIR-TSEIR (P< 0.05). The real image quality of SPAIR was better than over conventional TSEIR FS on clinical abdominal MRI scans.

• 보존과학연구
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• s.31
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• pp.155-171
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• 2010

Wooden cultural heritages have many factors of fires and structural characteristics vulnerable to the fire extinguishing. Also, they are surrounded with forests and so remote from fire stations, which make it difficult to handle it quickly when fires break out. Wooden cultural heritages made of wood materials belong to the general fire in a Class A. Taking characteristics such as a smoldering and a backfire from the that fire of wooden materials into consideration, extinguishing the fire by the cooling system is the most effective. If the fire can't be put out at the early stage, it is almost impossible to protect wooden cultural heritages from the fire, because wooden structures can be destroyed in a high temperature and in a short time and it takes around average 7 minutes to reach its peak of flames in the process of a fire. According to the geographical and environmental situation of the cultural heritages, currently, the fire-prevention facilities such as the auto fire detector for the prompt detection, the water mist fire suppression system for the 1st early and urgent fire suppression and the outdoor fire hydrant and the water curtain etc. for the 2nd full-scale suppression and the prevention of the fire gaining force are being installed for the wooden cultural heritages.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.41 no.6
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• pp.448-457
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• 2013

This paper presents the design of an active flutter suppression system for flexible wing using sliding mode control method. The aerodynamic force generated by the motion of a flexible wing control surface is utilized as control force. For this purpose, aeroservoelastic model is formulated by blending aeroelastic model, control surface actuator model, and gust model. A sliding mode controller is designed for active flutter suppression on the aeroservoelastic model in conjunction with Kalman filter that estimates the system states based on the measured output. The performance of the designed controller is demonstrated via numerical simulation for the representative flexible wing model.