• Korean Journal of Microbiology
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• v.45 no.2
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• pp.105-111
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• 2009

Norovirus (NV) with a variety of genotypes, a member of the family Caliciviridae, causes acute nonbacterial gastroenteritis in humans. We determined the nucleotide sequence of three open reading frames (ORFs) of a NV Korean strain and characterized the genetic relationship with others. The Korean strain designated Hu/NLV/Gunpo/2006/KO was isolated from the stool specimen of a 2-year-old female suffering from gastroenteritis. By performing reverse transcription and PCR amplification, three overlapping cDNAs were synthesized and used for direct sequencing. We found that like other NVs, this strain contains three ORFs: ORF1, 5,100 bp; ORF2, 1,647 bp; ORF3, 765 bp. Of 35 NVs, ORF1 had a level of genetic diversity lower than ORF2 and ORF3, of which the C-termini of the ORF2 and ORF3 showed a relatively high degree of genetic diversity. Phylogenetic analyses indicated that the Korean strain belonged to genogroup II, with Saitama U1, Gifu'96, Mc37, and Vietnam 026 being formed a single genetic cluster. The nucleotide sequence information of three ORFs of a NV Korean isolate will be useful not only for the development of a diagnostic tool and understanding of genetic relationship, but also provide important basic information for the functional analysis of their gene products.

• Journal of The Korean Association For Science Education
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• v.33 no.7
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• pp.1312-1328
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• 2013

In this study, we investigated preservice secondary science teachers' uses of curriculum materials in curriculum design through a case study. Two preservice science teachers at a college of education in Seoul participated in this study. We interviewed them about their beliefs on teaching and learning prior to their teaching students. We then observed their teaching and collected all of the teaching/learning materials. Semi-structured interviews were also conducted before and after the instructions. Their uses of curriculum materials were systematically analyzed in the aspects of reading, evaluating and adapting curriculum materials. The analyses of the results revealed that their uses of curriculum materials had a significant difference in curriculum design. There was a difference in the way of reading curriculum materials that derived from different perspectives of curriculum reconstruction. The perspectives of curriculum reconstruction also affected the way of adapting curriculum materials. While the 'adding' was an important adaptation in curriculum design with active perspectives, the 'changing' was an important one with passive perspectives. In addition, the degrees of evaluating curriculum materials from the learners' views depended on their beliefs on teaching and learning. It was also connected to qualitative differences of adaptation in 'increasing student control over an activity' and 'increasing teacher control over an activity'. Educational implications of these findings are discussed.

• Phonetics and Speech Sciences
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• v.12 no.1
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• pp.19-31
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• 2020

The purpose of this study is to observe the realization of pause and breath groups from adult speakers and to examine how gender, generation, and tasks can affect this realization. For this purpose, we analyzed forty-eight male or female speakers. Their generation was divided into two groups: young, old. Task and gender affected both the realization of pause and breath groups. The length of the pause groups was longer in the read speech than in the spontaneous speech and female speech. On the other hand, the length of the breath group was longer in the spontaneous speech and the male speech. In the spontaneous speech, which requires planning, the speaker produced shorter length of pause group. The short sentence length of the reading material influenced the reason for which the length of the breath group was shorter in the reading speech. Gender difference resulted from difference in pause patterns between genders. In the case of the breath groups, the male speaker produced longer duration of pause than the female speaker did, which may be due to difference in lung capacity between genders. On the other hand, generation did not affect either the pause groups or the breath groups. The generation factor only influenced the number of syllables and the eojeols, which can be interpreted as the result of the difference in speech rate between generations.

• Radiation Oncology Journal
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• v.17 no.3
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• pp.256-260
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• 1999

Purpose : An investigation has been carried out on the factors which affect the response reading of thermoluminescent dosimeters (TLD-100) loaded with thin material in high energy Photon. The aim of the study was to assess the energy response of TLD-100 to the therapeutic ranges of photon beam. Materials and Methods : In this technique, TLD-100 (abbreviated as TLD) chips and three different thin material (Tin, Gold, and Tissue equivalent plastic plate) which mounted on the TLD chip were used in the clinical photon beam. The thickness of each metal plates was 0.1 mm and TE plastic plate was 1 mm thick. These compared with the photon energy dependence of the sensitivities of TLD (normal chip), TLD loaded with Tin or Gold plate, for the photon energy range 6 MV to 15 MV, which was of interest in radiotherapy. Results : The enhancement of surface dose in the TLD with metal plate was clearly detected. The TLD chips with a Gold plate was found to larger response by a factor of 1.83 in 10 MV photon beam with respect to normal chip. The sensitivity of TLD loaded with Tin was less than that for normal TLD and TLD loaded with Gold. The relative sensitivity of TLD loaded with metal has little energy dependence. Conclusion : The good stability and linearity with respect to monitor units of TLD loaded with metal were demonstrated by relative measurements in high energy Photon ($6\~15$ MV) beams. The TLD laminated with metals embedded system in solid water phantom is a suitable detector for relative dose measurements in a small beam size and surface dose.

• Journal of Korean Library and Information Science Society
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• v.49 no.2
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• pp.201-220
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• 2018

The purpose of this study is to explore problems within bibliotherapy research of the 15 thesis papers aimed at improving self esteem, and then to explore development plan. In the current study on bibliotherapy, the problems with bibliotherapy are presented in five aspects. First, there is a lack of professionalism and role of counselor who plays the most important role in bibliotherapy. Second, the situation of the internalizer as an internalizer of bibliotherapy was not reflected in the bibliotherapy program. Third, the lack of diversity in the bibliotherapy program does not keep the reader's interest in bibliotherapy. Fourth, bibliotherapy reading material is limited to text material, which lacks the use of various media. Fifth, there is insufficient validity for the test paper that measures the effectiveness of the reader's bibliotherapy in terms of research methods. Several development plan are proposed based on the factors that affect bibliotherapy. First, it is necessary to develop and train teaching materials to secure expertise of bibliotherapy counselors. Second, it is necessary to develop data on the various media on suitable for bibliotherapy material. Third, it is necessary to review the test paper that can accurately measure the effectiveness of bibliotherapy.

• The Journal of the Korea Contents Association
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• v.9 no.12
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• pp.730-734
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• 2009

The ottonello method is used to see a front view image of cervical 1-7 number. The study found a systematic examination method to find a better image through an experiment using metronome. The results are as follows: In an evaluation of MTF, when used 0.5 standard of MTF, oral explanation resulted 1.2 LP/mm, Moderato-100 1.4 LP/mm, Allegro-138 1.6 LP/mm, Presto-184 2.4 LP/mm. Among them presto-184 showed the highest sharpness with 2.4 LP/mm. In an image reading by a medicine doctor of radiology, when oral explanation was 17%, Moderato-100 15%, Allegro-138 18%, Presto-184 50%. Among themprest-184 was evaluated as the best image. The result of was a method to reduce an image repeat, patients radiation exposure, patients waiting time for examination, material and so on.

• Korean Journal of Head & Neck Oncology
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• v.23 no.1
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• pp.21-25
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• 2007

Background：Squamous cell carcinoma(SCC)of the palatine tonsils represents approximately 15-23% of all intraoral SCC. The most frequently reported risk factors for oropharyngeal cancer are smoking and alcohol. In a recent overview of HPV and tonsillar squamous cell carcinoma(TC), 51% contained HPV DNA, and HPV-16 being the most frequent type. We aimed to clarify whether HPV directly effects on the oncogenesis and biologic behavior of TC by comparison with infection prevalence, and physical status of virus. Material and Method：We used HPV genotyping DNA chip(Biocore, Korea, Seoul) arrayed by multiple oligonucleotide probes of L1 sequence of 26 types of HPV and HPV genotypes are identified by fluorescence scanner. The copy numbers of HPV E2 and E6 open reading frames(ORF) were assessed using a TaqMan-based 5'-exonuclease quantitative real-time PCR assay. The ratio of E2 to E6 copy numbers was calculated to determine the physical status of HPV-16 viral gene. Results：We observed a significant difference in HPV prevalence between 52 TCs and 69 CFTs(73.1% vs. 11.6%), and most of the HPVs were type 16(87.2%)and non-episomal(94.1%) state. Conclusions：This study regarding HPV infection prevalence and mechanism in the largest population of palatine tonsillar squamous cell carcinoma with chronic follicular tonsillitis revealed significant difference pf HPV prevalence between TC and CFT. Most of HPV were 16 type and integrated or mixed, HPV-16 integration could be directly related to tonsillar carcinogenesis.

• Korean Journal of Cognitive Science
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• v.27 no.2
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• pp.221-245
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• 2016

Peer assessment refers to having students, rather than the instructor, make assessments of one another's work. Peer assessment is often used as a tool to train writing skills or a tool to apply or extend learning in higher education. Park(2016) recently proposed a system which utilizes peer assessment as a part of preparatory activity for college courses. Before weekly class, students studied given material on their own, wrote a one page essay on a given question based on their reading, and assessed the essays of other students. In this study, the system was implemented in undergraduate courses at S University over 2 semesters and the results were analyzed. The reliability of weekly scores given by students was not very high, but the correlation was high between the cumulative scores given by students across weeks and the scores of the end of the term paper assessed by the instructor. Based on these findings, the possibility of utilizing the results of the peer assessments as part of the final grades was discussed.

• The Journal of the Korea Contents Association
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• v.13 no.3
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• pp.485-494
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• 2013

In this paper, both content analysis and Romey analysis were employed to analyze 'Basic Information Technology' textbooks in technical high schools. Not only was the content analysis employed to study the organization and contents of the textbooks, but also the Romey analysis was applied so as to determine inquisitive tendency on four factors - text, data, activity and evaluation. The results from content analysis showed that the total number of pages, reading material, the number of concepts introduced in each section, and the use of application software demonstrated a discrepancy among textbooks. Also, Romey analysis showed that while the section 'text' was written with relatively low inquiry tendency for its authoritative tone, two textbooks showed high inquisitive tendency for section 'activity'. Finally, based on the obtained results, the ways to improve 'Basic Information Technology' textbooks were proposed.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.3 no.3
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• pp.154-160
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• 1970

The present paper deals with the growth of yellow croaker by scale age reading. This study is based on material from 596 specimens caught by the Danish seine in the Yellow Sea during the period from June 1967 to April 1968. Ring marks of the scale were formed from April to July, corresponding to the spawning season of the fish reported by Bae (1960). Growth rate of each radius of the ring was approximately 0.73. The relationship between the total length and radius of scales, and the relationship between the body weight and total length are represented by the following equations respectively: L=61.350R+50.184 $$W=4.298L^{3.227}\times10^{-3}$$ Maximum total length calculated by the diagram of Walford's growth transformation, $$L_{n+1}=0.6866L_n+10.8730$$, was 346.9mm. Growth curve of the fish can be expressed by the following von Bertalanffy's equation : $$L_t=346.9(1-e^{-0.376(t+0.609)})$$