• Advances in Traditional Medicine
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• 제10권4호
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• pp.239-253
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• 2010

Coenzyme $Q_{10}$ ($CoQ_{10}$, or ubiquinone) is an electron carrier of the mitochondrial respiratory chain (electron transport chain) with antioxidant properties. In view of the involvement of $CoQ_{10}$ in oxidative phosphorylation and cellular antioxidant protection a deficiency in this quinone would be expected to contribute to disease pathophysiology by causing a failure in energy metabolism and antioxidant status. Indeed, a deficit in $CoQ_{10}$ status has been determined in a number of neuromuscular and neurodegenerative disorders. Primary disorders of $CoQ_{10}$ biosynthesis are potentially treatable conditions and therefore a high degree of clinical awareness about this condition is essential. A secondary loss of $CoQ_{10}$ status following HMG-CoA reductase inhibitor (statins) treatment has been implicated in the pathophysiology of the myotoxicity associated with this pharmacotherapy. $CoQ_{10}$ and its analogue, idebenone, have been widely used in the treatment of neurodegenerative and neuromuscular disorders. These compounds could potentially play a role in the treatment of mitochondrial disorders, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, Friedreich's ataxia, and other conditions which have been linked to mitochondrial dysfunction. This article reviews the physiological roles of $CoQ_{10}$, as well as the rationale and the role in clinical practice of $CoQ_{10}$ supplementation in different neurological diseases, from primary $CoQ_{10}$ deficiency to neurodegenerative disorders. These will help in future for treatment of patients suffering from neurodegenerative disease.

• Journal of applied mathematics & informatics
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• 제36권5_6호
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• pp.555-565
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• 2018

The main subject of this paper is to introduce the (p, q)-Euler polynomials and obtain several interesting symmetric properties of the modified (p, q)-Hurwitz Euler Zeta function with regard to (p, q) Euler polynomials. In order to get symmetric properties, we introduce the new (p, q)-analogue of Euler polynomials $E_{n,p,q}(x)$ and numbers $E_{n,p,q}$.

• Journal of the Korean Data and Information Science Society
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• 제17권1호
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• pp.41-52
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• 2006

Because most common assumption is normality in statistical analysis, testing normality is very important. The Q-Q plot is a powerful tool to test normality with full samples in statistical package. But the plot can't test normality in type-II censored samples. This paper proposed the modified the Q-Q plot and the modified normalized sample Lorenz curve(NSLC) for normality test in the type-II censored samples. Using the two Hodgkin's disease data sets and the type-II censored samples, we picture the modified Q-Q plot and the modified normalized sample Lorenz curve.

• 호남수학학술지
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• 제41권2호
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• pp.243-268
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• 2019

The main aim of this paper is to study some growth properties of composite entire functions on the basis of relative $(p,q)-{\varphi}$ type and relative $(p,q)-{\varphi}$ weak type where p and q are any two positive integers and ${\varphi}(r):[0,+{\infty}){\rightarrow}(0,+{\infty})$ be a non-decreasing unbounded function.

• 한국수학교육학회지시리즈B:순수및응용수학
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• 제29권1호
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• pp.69-91
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• 2022

In the paper we establish some new results depending on the comparative growth properties of composite transcendental entire and meromorphic functions using relative (p, q, t)L-th order, relative (p, q, t)L-th type and relative (p, q, t)L-th weak type and that of Wronskian generated by one of the factors.

• Journal of applied mathematics & informatics
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• 제41권1호
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• pp.167-179
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• 2023

In this paper, we investigate solutions of equations which are linear (p, q)-difference equation of higher order by using (p, q)-derivative and integral. We also derive the solution of equation in the case of second order.

• Journal of Applied and Pure Mathematics
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• 제6권1_2호
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• pp.1-11
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• 2024

In this paper, we define a new fully modified q-poly-Euler numbers and polynomials of the first type by using q-polylogarithm function. We derive some identities of the modified polynomials with Gaussian binomial coefficients. We also explore several relations that are connected with the q-analogue of Stirling numbers of the second kind.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제10권10호
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• pp.269-276
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• 2021

최근 스마트 센서는 다양한 환경에서 사용되고 있으며, 애드혹 센서 네트워크 (ASN) 구현에 대한 연구가 활발하게 진행되고 있다. 그러나 기존 센서 네트워크 라우팅 알고리즘은 특정 제어 문제에 초점을 맞추며 ASN 작업에 직접 적용할 수 없는 문제점이 있다. 본 논문에서는 Q-learning 기술을 이용한 새로운 라우팅 프로토콜을 제안하는데, 제안된 접근 방식의 주요 과제는 균형 잡힌 시스템 성능을 확보하면서 효율적인 에너지 할당을 통해 ASN의 수명을 연장하는 것이다. 제안된 방법의 특징은 다양한 환경적 요인을 고려하여 Q-learning 효과를 높이며, 특히 각 노드는 인접 노드의 Q 값을 자체 Q 테이블에 저장하여 데이터 전송이 실행될 때마다 Q 값이 업데이트되고 누적되어 최적의 라우팅 경로를 선택하는 것이다. 시뮬레이션 결과 제안된 방법이 에너지 효율적인 라우팅 경로를 선택할 수 있으며 기존 ASN 라우팅 프로토콜에 비해 우수한 네트워크 성능을 얻을 수 있음을 확인하였다.

• 대한수학회보
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• 제47권3호
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• pp.575-583
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• 2010

In this paper, new q-analogs of Genocchi numbers and polynomials are defined. Some important arithmetic and combinatoric relations are given, in particular, connections with q-Bernoulli numbers and polynomials are obtained.

• 충청수학회지
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• 제26권3호
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• pp.641-645
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• 2013

In this article, we show that the modular equation ${\Phi}_p^{T_q}(X,Y)$ of Thompson series $T_q$ corresponding to ${\Gamma}_0(q)+q$ gives an affine model of a modular curve $X_0(pq)+q$.