• Molecules and Cells
• /
• v.37 no.5
• /
• pp.412-417
• /
• 2014

It has been reported that exogenously introduced micro-RNA (exo-miRNA) competes with endogenously expressed miRNAs (endo-miRNAs) in human cells, resulting in a detectable upregulation of mRNAs with endo-miRNA target sites (TSs). However, the detailed mechanisms of the competition between exo- and endo-miRNAs remain uninvestigated. In this study, using 74 microarrays that monitored the whole-transcriptome response after introducing miRNAs or siRNAs into HeLa cells, we systematically examined the derepression of mRNAs with exo- and/or endo-miRNA TSs. We quantitatively assessed the effect of the number of endo-miRNA TSs on the degree of mRNA derepression. As a result, we observed that the number of endo-miRNA TSs was significantly associated with the degree of derepression, supporting that the derepression resulted from the competition between exo- and endo-miRNAs. However, when we examined whether the site proficiency of exo-miRNA TSs could also influence mRNA derepression, to our surprise, we discovered a strong positive correlation. Our analysis indicates that site proficiencies of both exo- and endo-miRNA TSs are important determinants for the degree of mRNA derepression, implying that the derepression of mRNAs in response to exo-miRNA is more complex than that currently perceived. Our observations may lead to a more complete understanding of the detailed mechanisms of the competition between exo- and endo-miRNAs and to a more accurate prediction of miRNA targets. Our analysis also suggests an interesting hypothesis that long 3'-UTRs may function as molecular buffer against gene expression regulation by individual miRNAs.

• Journal of Digital Convergence
• /
• v.12 no.3
• /
• pp.309-316
• /
• 2014

The main purpose of this study is to find out how strategy orientation influences to performance in general hospitals, and to analyze the effect of the general hospital structure and its size to the relationship between independence variables and performance variable. To achieve the goal we set 3 sub-dimension, customer orientation, competition orientation and care skill orientation based on comprehensive consideration of related studies, and established 5 hypothesis. Survey data for statistic analysis have been collected from 176 members of 5 general hospitals in Korea from 1July to 13 October, 2013. We found that three dimensions of strategy orientation influence to performance significantly. We also found that moderating effect of general hospital structure and its size is partially supported. General hospital structure and its size moderates only the relationship between competition orientation and performance.

• Ecology and Resilient Infrastructure
• /
• v.7 no.3
• /
• pp.208-217
• /
• 2020

A biopolymer based on microorganism-derived β-glucan and xanthan gum is being studied as a new eco-friendly material that stabilizes the riverbank slope, and also promotes vegetation growth. However, it is still inconclusive whether biopolymers have a positive effect on plant performance in the riverbanks which are subjected to various climatic factors and plant competitions. For a practical ecological evaluation of the biopolymers, their effect on plant growth promotion was studied in a natural environment. Considering the relationship between competition and plant community formation, the effects of biopolymers on competition were also investigated. For four plant species (Echinochloa crus-galli, Pennisetum alopecuroides, Leonurus japonicus, and Coreopsis lanceolata), the biopolymer effects under intra/interspecific competition were tested at the riverbank (20 m × 10 m) near Samjigyo Bridge in Damyang-gun, Jeollanam-do. A biopolymer powder was mixed with water and commercial soil following the manufacturer's recommendations. The soil mixed with the biopolymer was filled in a pot or applied to the surface of the commercial soil with a thickness of 3 cm. Across the competition treatments, the biopolymer treatment promoted root growth of the target plant species and decreased the specific leaf area. The total biomass and shoot dry weight of P. alopecuroides increased in response to the biopolymer treatment. The competition treatment decreased the total biomass and shoot dry weight compared to the case without competition. Notably, such a competitive effect was similar in all the biopolymer treatments. Thus, biopolymers, when mixed with soil, promote the growth of some plant species, but do not appear to affect the competitive ability of plants.

• Journal of Digital Convergence
• /
• v.18 no.9
• /
• pp.441-451
• /
• 2020

The study was conducted with the aim of identifying the impact of competition anxiety on dance immersion and performance in high school students majoring in dance. As of 2020, online surveys were conducted on students majoring in dance at high schools in Seoul and the metropolitan area. A total of 222 people's data were processed by applying t-test, one-way variable analysis, correlation and multiple regression analysis through SPS 18.0 for Windows, resulting in the following conclusions. First, male students were more confident in their condition than female students, and students who recognized that their family's economic power was in the middle class were more aware. In addition, it was found that the group perceived that economic power was at the top of the list was higher than the median. Second, cognitive anxiety and self-confidence have been shown to have a static effect on immersion into dance. Third, cognitive anxiety and self-confidence have been shown to have a static effect on the achievement of uselessness. Fourth, immersion in dance appeared to be a powerful parameter related to competition anxiety and achievement of dance. To sum up the above conclusions, competition among high school students majoring in dance has been shown to increase their performance by immersing themselves in dance, but further studies of these psychological variables are expected to have side effects.

• Korean small business review
• /
• v.41 no.1
• /
• pp.29-51
• /
• 2019

This study investigates how SMEs' (small and medium-sized enterprises) financing strategies affect firm valuation. Given that information asymmetry is engaged in firm valuation in the stock market, investors interpret the meanings of debt financing depending on how SMEs construct the portfolio of financing strategies (retained earnings vs debt financing), thereby making investment decision. Specifically, given that SMEs' debt financing has two meanings in the market signals, called "benefit" and "cost", this study postulates that firm valuation will be differently made by investors, depending on how they interpret the meanings of debt financing under choice competition between retained earnings and debt financing. In this study, we argue that under choice competition, as a SME's debt proportion increases, the "cost" signal outweighes the "benefit" signal, thereby decreasing firm valuation. Moreover, the effect of such signal can be contingent on the SME's characteristics-firm visibility. These ideas are examined using 363 U.S. SMEs ranging from 1971 to 2010. The fixed-effects models estimating Tobin's q show that under choice competition, a SME's debt proportion has a negative impact on firm valuation and that the firm's high visibility mitigates the effect of "cost" signal. In conclusion, this study sheds new light on how investors' interpretations of SMEs' financing strategies affect firm valuation.

• Journal of the Korea Convergence Society
• /
• v.6 no.4
• /
• pp.169-176
• /
• 2015

The purpose of this study was to analyze the relationship between sports confidence and class satisfaction according to adolescents' participation in marine sports. First, as a result of analyzing the correlation between sports confidence and class satisfaction, confidence on specific sports had a positive (+) effect on class contents, class style, and class effect, and had a negative (-) effect on physical education teachers. Competition orientation had a positive (+) effect on class contents, class style, and class effect. State sports confidence had a positive (+) effect on all the sub-factors of class satisfaction. Second, as a result of analyzing the effect of sports confidence on class satisfaction, class contents and class style had positive (+) effects on competition orientation and state sports confidence, and class environment and physical education teachers had positive (+) effects on state sports confidence and negative (-) effects on competition orientation.

• Journal of Information Technology Services
• /
• v.19 no.1
• /
• pp.17-35
• /
• 2020

The Korea government has been pursuing various policies to find a new industrial growth engine based on ICT (Industry and Communication Technology). However, ICT industry recently faces a serious crisis due to a lack of fundamental competitiveness and capital and technological gap with other countries. Accordingly, it is necessary for ICT industry to recognize the rapidly changing competitive business environment and to establish appropriate value-based strategies. This paper analyses factors affecting value-based strategy in the Korean ICT industry using 10 years data set. The result shows that the value-based strategy in the Korean ICT companies has a significant influence on their financial performance. In addition, it is confirmed that the competition level in the industry has a significant moderating effect on this relationship. In addition, when the companies are categorized based on performance, it is confirmed that there is a significant difference in competition level and value-based strategy in each categories. The results of this paper are expected to suggest implications for the effective use of balanced value-based strategies in the ICT industry.

• Journal of Distribution Science
• /
• v.18 no.1
• /
• pp.47-57
• /
• 2020

Purpose: This study seeks to bridge between the research by Lawrence (1999) and Retegan (1992), where the focus of TQM on his studies rests on customer satisfaction. Whereas in this study trying to recompile TQM by involving the variables Innovation and competitive advantage to stimulate managerial performance improvement where performance measurements include various measurements such as financial performance, marketing performance, and production performance in the property industry. Research design, data, and methodology: Total sample are 105 respondents coming from middle to top level of management in the property sector in Indonesia. To empirically prove the results of this study using multiply regression analysis as a test tool for analysis. Results and Findings: The results of this study confirm that TQM has a positive effect on market competition, innovation, and company performance indirectly. However, it does not have a significant impact if it is directly related to TQM on company performance. In this case, TQM for property companies in Indonesia would not have been possible without the role of innovation and market competition. So that the managerial implications of this study also confirm that TQM is essential and feels obligatory to be implemented optimally.

• Knowledge Management Research
• /
• v.12 no.3
• /
• pp.73-96
• /
• 2011

Recent market saturation makes the local retailers consider an attempt to innovate the market with the retailer's brand. This is the retailers' efforts to expand the market control through the enhancement of private brands. As the competition among manufacturers extends to the competition between manufacturers and retailers, the marketing knowledges of manufacturers need to be diversified to the ones that can be applied to the manufacturers and retailers due to their bilateral competition. This research concentrates on the customer acquisition strategy (attack strategy) and customer retention strategy (defense strategy) in the place of both sides of manufacturers and retailers. Also this research targets to develop the differential marketing strategies for target market's National Brand(NB)/Private Brand(PB) purchase by analyzing individual customer's purchase probability on repurchase and switch-purchase of NB and PB. This study is based on the data of frequently consumed product, tomato ketchup on scanner panel from the ERIM data of University of Chicago, USA. This study compares and analyzes the NB and PB repurchases and switch-purchase of 4 types. The comparisons provide the informations that which factors should be managed for the attack strategy, the defense strategy, and the differential marketing strategies both for manufacturers and retailers. This research is expected to contribute on cumulating the industrial knowledges of retailers' and manufacturers' survival strategy, expecially focusing on the effect of marketing factors and consumer-characteristic factors.

• Korean Journal of Human Ecology
• /
• v.24 no.6
• /
• pp.875-887
• /
• 2015

The analysis in this work is about costumes among the rhythmic gymnasts in competition, which is intended to develop designs about rhythmic gymnastics costume and provide the basic material from the results. In its research method and range, the general information on rhythmic gymnastics was reviewed in literature and the case analysis was followed about costumes of world high rankers in competition during 2012~2015 seasons. Research showed the following results. First, leotard took a shape of skirt-added one-piece type, where a combination with long tight sleeve, round neck line, and stand-up collar had a relatively higher percentage in design. With regard to a bottom line of skirt, an amorphous type was most common that highlights rhythmical beauty without any particular form. This design exposed shoulders and waists on both sides, expressing the feminine beauty. Second, in color used mainly, white appeared most frequently. In its combination, more than three were employed. Third, transparent mesh was applied as basic, where lace and chiffon were used. Abstract pattern took the highest portion in pattern. Particularly, crystal bead or gradation coloring was used to maximize the visually splendid image, giving an effect of optical illusion as if neckless clothing, choker, bracelet, or glove were worn. Fourth, it appeared that the costume for each event was changed in every season, when only music was substituted but the same earlier costume was put on for the different event.