• 대한한방내과학회지
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• 제40권6호
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• pp.1303-1310
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• 2019

Objectives: Drug-induced Parkinsonism has similar symptoms to Parkinson's disease, but each has different causes. Drug-induced Parkinsonism accounts for the largest proportion of secondary Parkinsonism We report a outpatient case of drug-induced Parkinsonism after taking Risperidone, an atypical antipsychotic. Method: With discontinuing of antipsychotic drug, modified Yigan-san extract was administered for 12 weeks, and acupuncture and electroacupuncture procedures were performed 20 times. Results: Abnormal Involuntary Movement Scale (AIMS) score decreased from 23 to 3 during 59 days of treatment period without adverse events and worsening of depression. The Patient was highly satisfied. Conclusion: Modified Yigan-san and electroacupuncture (GB34) can be used as an treatment option in patients with drug-induced Parkinsonism.

• 대한전자공학회논문지SD
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• 제44권2호
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• pp.19-24
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• 2007

최근 대용량 데이터 전송이 이루어지면서 하드웨어의 복잡성과 전력, 가격 등의 이유로 인하여 입력데이터와 클럭을 함께 수신 단으로 전송하는 병렬버스 기법보다는 시리얼 링크 기법이 메모리 인터페이스에 많이 사용되고 있다. 시리얼 링크 기법은 병렬버스 기법과는 달리 클럭을 제외한 데이터 정보만을 수신단으로 보내는 방식이다. 클럭 및 데이터 복원 회로(clock and data recovery 혹은 CDR)는 시리얼 링크의 핵심 블록으로, 본 논문에서는 그래픽 DRAM 인터페이스용의 5.4Gb/s half-rate bang-bang 클럭 및 데이터 복원회로를 설계하였다. 이 회로는 half-rate bang-bang 위상검출기, current-mirror 전하펌프, 이차 루프필터, 및 4단의 차동 링타입 VCO로 구성되었다. 위상 검출기의 내부에서 반 주기로 DeMUX된 데이터를 복원할 수 있게 하였고, 전체 회로의 용이한 검증을 위해 MUX를 연결하여, 수신된 데이터가 제대로 복원이 되는지를 확인하였다. 설계한 회로는 66㎚ CMOS 공정파라미터를 기반으로 설계 및 layout하였고, post-layout 시뮬레이션을 위해 5.4Gb/s의 $2^{13}-1$ PRBS 입력데이터를 사용하였다. 실제 PCB 환경의 유사 기생성분을 포함하여 시뮬레이션 한 결과, 10psRMS 클럭 지터 및 $40ps_{p-p}$ 복원된 데이터 지터 특성을 가지고, 1.8V 단일 전원전압으로부터 약 80mW 전력소모를 보인다.

• 대한한의학회지
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• 제23권1호
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• pp.92-99
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• 2002

Objectives : To investigate the role of Meridian flow on acupuncture effect, we observed the therapeutic effects of electroacupuncture (EA) after Meridian blocking with pressure in arthritic rats. Methods : To make reliable and local monoarthritis, $40{\;}{\mu}l$ complete Freund's adjuvant was injected into the tibio-tarsal joint. EA was applied on acupoint GB30 while 5 Pascal pressure was added to the middle of the Gall bladder Meridian around GB31 between acupoint GB30 and arthritic foci (ipsilateral meridian blocking: IB) or opposite part of IB (contralateral part blocking: CB). To observe the change of arthritis, extension and flexion pain scores and circumferential differences were evaluated once a week. Results : EA stimulation without blocking reduced arthritic pain significantly. IB abolished the acupuncture effects and there was no statistical difference with the arthritic control group, whereas the CB group still showed the therapeutic effects of acupuncture. Conclusions : This finding strongly supports that the Meridian blocking with local pressure reduced the therapeutic effect of EA.

• 전자통신동향분석
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• 제19권5호통권89호
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• pp.107-113
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• 2004

광섬유의 분산특성에 의한 신호의 왜곡을 완화하기 위한 방법의 하나로 수신단에서 전기적 등화에 의한 분산 보상법이 개발되고 있다. 이 기술은 이미 유무선 전송에 널리 사용되었으며 근래에 고속의 광 전송에도 도입되고 있다. 본 논문은 이와 관련된 기술을 소개하고자 한다. 현재까지 비교적 구현이 용이한TF(Transversal Filter)와 DFE(Decision Feedback Equalizer)에 관한 결과가 주로 발표되었다. 전송속도는 대부분이 현재 상용화된 10Gb/s이며 40Gb/s에 관한 결과도 최근 발표되었다. 등화기의 효과적인 적응 제어 방법에 관하여도 몇 가지 기술이 제시되었다. 이 기술의 대표적인 적용분야는 단일모드 광섬유의 편광모드 분산에 대한 보상이며 그 외에 다중모드 광섬유의 모드간 분산 보상에도 활용될 수 있다. 이 기술의 사용으로 전송거리의 확장에 의한 경제성 향상을 기대할 수 있다.

• 운동영양학회지
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• 제14권2호
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• pp.63-68
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• 2010

This study evaluated the effects of high pressured red ginseng(HRG) and ginseng berry(GB) supplementation on lipid profiles and run to exercise time in SD rats. Five weeks-old male rats were randomly assigned into six groups, ie. control group(AC: n = 8), exercise group(AE: n = 7), general extracted red ginseng group(C: n = 8), HRG group(high density D: n = 8, low density E: n = 7), and HRG + GB group(F: n = 7). The AC and AE groups had a supplementation of AIN-93G, and AE group performed 40 min treadmill exercise five times per week for five weeks. E, C, D, and F groups had a supplementation composed of general extracted red ginseng(GRG), HRG(250 mpk and 500 mpk), and HRG(250 mpk) + GB(167 mpk) in the AIN-93G. Main results of the study were as follow 1) the duration of running time to exhaustion was higher in exercise group compared to other groups. HRG had no effect on run to exhaustion time, but, GRG and HRG + GB showed longer run time than control groups. 2) Blood TC, TG, HDL-C and liver TG showed no difference between groups, but, liver TC showed lower level in the HRG groups than other groups. It was concluded that the 5 weeks of supplementation of HRG extract would have positive effects on liver cholesterol, and GRG and HRG + GB have a positive effect on exercise performance tested run to exhaustion time, but, we can not find a positive effect of supplementation of HRG on exercise performance.

• JSTS:Journal of Semiconductor Technology and Science
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• 제10권3호
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• pp.176- 184
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• 2010

A low-power inductorless 1:4 DEMUX and a 4:1 MUX for a 90 nm CMOS are presented. The DEMUX can be operated at a speed of 25 Gb/s with the power supply voltage of 1.05 V, and the power consumption is 8.9 mW. The area of the DEMUX core is $29\;{\times}\;40\;{\mu}m^2$. The operation speed of the 4:1 MUX is 13 Gb/s at a power supply voltage of 1.2 V, and the power consumption is 4 mW. The area of the MUX core is $30\;{\times}\;18\;{\mu}m^2$. The MUX/DEMUX mainly consists of differential pseudo-NMOS. In these MUX/DEMUX circuits, logic swing is nearly rail-to-rail, and a low $V_{dd}$. The component circuit is more scalable than a CML circuit, which is commonly used in a high-performance MUX/DEMUX. These MUX/DEMUX circuits are compatible with conventional CMOS logic circuit, and it can be directly connected to CMOS logic gates without logic level conversion. Furthermore, the circuits are useful for core-to-core interconnection in the system LSI or chip-to-chip communication within a multi-chip module, because of its low power, small footprint, and reasonable operation speed.

• ETRI Journal
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• 제34권6호
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• pp.838-846
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• 2012

This paper proposes a cost-effective hybrid-type power budget extender (PBEx) that can provide a high power budget of over 45 dB in an asymmetric 10-Gb/s Ethernet passive optical network (10/1G-EPON). The hybrid-type 10/1G-EPON PBEx comprises a central office terminal (COT) and remote terminal (RT) module supporting four channels and uses a coarse wavelength division multiplexing (CWDM) technology between the COT and RT for a reduction of fiber cost and efficient access network design. The proposed 10/1G-EPON PBEx can provide over a 40-km reach and 128-way split per CWDM wavelength with no modification of a legacy 10/1G-EPON system and can satisfy the error-free service in $10^{10}$ packet transmission.

• Journal of the Optical Society of Korea
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• 제13권2호
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• pp.227-233
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• 2009

We investigated the polarization-mode dispersion (PMD) tolerance for 40Gb/s non-return to zero (NRZ), duobinary NRZ, return to zero (RZ), carrier-suppressed RZ (CS-RZ), and duobinary-carrier-suppressed RZ (DCS-RZ) modulation formats with a forward error correction (FEC) coding. The power penalty has been calculated as a measure of the system performance due to PMD. After comparison of the PMD tolerance of various modulation formats, our results suggest that RZ signals have the best tolerance against the effect of first-order PMD only. The duobinary NRZ modulation format is most resilient to PMD when both first- and second-order PMD are considered. However, the duobinary NRZ modulation format is the most sensitive to the incident angle of the input signal to a fiber axis in the presence of first- and second-order PMD, leading to incident angle-dependent power penalty. The coding gain by FEC can cope with the power penalties induced by first- and second-order PMD up to a DGD value of 16ps.

• ETRI Journal
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• 제34권3호
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• pp.361-368
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• 2012

A complete high-frequency small-signal circuit model of a 40 Gb/s butterfly electroabsorption modulator integrated laser module is presented for the first time to analyze and optimize its electro-optic (E/O) response and reflection characteristics. An agreement between measured and simulated results demonstrates the accuracy and validity of the procedures. By optimizing the bonding wire length and the impedance of the coplanar waveguide transmission lines, the E/O response increases approximately 5% to 15% from 20 GHz to 33 GHz, while the signal injection efficiency increases from approximately 15% to 25% over 18 GHz to 35 GHz.

• Journal of Animal Science and Technology
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• 제61권2호
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• pp.55-60
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• 2019

Colibacillosis is one of the major health problems in young piglets resulting in poor health and death caused by Escherichia coli producing F18 pili and Shiga toxin 2e. It is pivotal to reduce colibacillosis in weaned piglets to enhance production performance. In this study, we evaluated synbiotics as the gut health improvement agents in the mouse model challenged with Shiga toxin-producing E. coli (STEC) isolated from piglets. Prebiotic lactulose was formulated with each $5.0{\times}10^6CFU/mL$ of Pediococcus acidilactici GB-U15, Lactobacillus plantarum GB-U17, and Lactobacillus plantarum GB 1-3 to produce 3 combinations of synbiotics. A total of 40 three weeks old BALB/c mice were randomly assigned to 4 groups (n = 10): a control group and 3 synbiotics treated groups. Each treatment groups were daily administrated with $5.0{\times}10^6CFU/mL$ of one synbiotics for the first week, and every 3 days during the second week. All the mice were challenged with $8.0{\times}10^8CFU/mL$ of STEC 5 days after animals began to receive synbiotics. Mice treated with synbiotics based on Pediococcus acidilactici GB-U15 and Lactobacillus plantarum GB-U17 significantly improved daily weight gain compared to mice in other groups. While mice treated with GB-U15 showed better fecal index, no significant differences were observed among groups. Gross lesion and histopathological evaluations showed that mice treated with GB-U15 moderately improved recovery from STEC infection. In conclusion, our results suggest that the synbiotics formulated with lactulose and Pediococcus acidilactici GB-U15 have potential benefits to prevent and improve colibacillosis in weaned piglets.