• Journal of Korea Water Resources Association
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• v.39 no.11 s.172
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• pp.961-968
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• 2006

Since a small harbor is often located near surf zone areas which have great influences of sediment transport, there is a great possibility that the sediment will be deposited inside of the harbor. The sediment transport occurring around the harbor entrance can't be explained by the wind wave and wave induced current. In this study, it was investigated the mechanism of the entrainment of sediment into a small harbor with permeable breakwater using hydraulic experiments in 3D wave basin. It is found out that the significant sediment entrainment produced when the mode of oscillation in the harbor became the 1st mode. In the case where the incident wave period was shorter than the period that caused higher mode oscillation in harbor, only a little amount of sediment entrainment took place. The vortex shedding from the top of secondary breakwater played very important roll in the entrainment of sediment into the harbor. It is also found that the small jetty attached at the top of secondary breakwater could effectively prevent the entrainment of sediment into the harbor.

• Korean Journal of Plant Resources
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• v.25 no.5
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• pp.507-516
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• 2012

Kidney stones occur in approximately 1% of the population during their lifetime. Although the development of extracorporeal shock wave lithotripsy (SWL) has revolutionized the theraphy of urolithiasis, the rate of recurrence of urothiasis, the rate of recurrenece of stones after SWL is about 50% within 10 years, which still represents serious problems for patienes. So to clarify the mechanism of Urocalum, and QS (Quercus salicina Blume) extract in the treatment of urolithiasis. Rat calcium oxalate urolithiasis was induced by oral administration of ethylene glycol and the vitamin D3 analog alfacalcidol for 14 days and QS extract was given to rats. After the last administration, we measured in urine, serum and renal oxidative stress marker. Ethylene glycol and alfacalcidol treatment increased BUN, creatinine, uric acid and XO. This increase was significantly suppressed by the administration of QS extract. These finding suggest that the QS extract plays a role in the prevention of stone formation and recureence in urolithiasis.

• The Journal of Korean Academy of Prosthodontics
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• v.44 no.1
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• pp.73-84
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• 2006

The importance of soft tissue response to implant abutments has become one of the major issues in current implant dentistry. To date, numerous studies have emphasized on maintaining connective tissue barriers in quantity, as well as in quality fir the long term success of dental implants. The cells mainly consisting the soft tissue around dental implants are fibroblasts and epithelial cells. The mechanism of the fibroblasts adhesions to certain substrata can be explained by the 'focal adhesion' theory. On the other hand, epithelial cells adhere tn the substratum via hemidesmosomes. The typical integrin-mediated adhesions of cells to certain matrix are called 'cell-matrix adhsions'. The focal adhesion complex of fibroblasts, in relation to the cell-matrix adhsions, consists of the extracellular matrix(ECM) such as fibronectin, the transmembrane proteins such as integrins, the intracellular cytoplasmic proteins such as vinculin, talin, and more, and the cytoskeletal structures such as filamentous actin and microtubules. The mechanosensory function of integrins and focal adhesion complexes are considered to play a major role in the cells adhesion, migration, proliferation, differentiation, division, and even apoptosis. The '3-D matrix adhesions' defined by Cukierman et al. makes a promising future for the verification of the actual process of the cell-matrix adhesions in vivo and can be applied to the field of implant dentistry in relation to obtaining strong soft tissue attachment to the implant abutments.

• Journal of the Korean Institute of Gas
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• v.4 no.3 s.11
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• pp.26-32
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• 2000

Because of the continuous growth of energy consumption, and also the tendency to site power lines and pipelines along the same routes, the close proximity of high voltage structures and metallic pipelines has become more and more frequent. Moreover, normal steady state and fault currents become higher as electric networks increase in size and power Therefore, there has been and still is a growing concern(safety of people marking contact with pipeline, risk of damage to the pipeline coating, the metal and equipment connected to pipeline, especially cathodic protection system) about possible hazards resulting from the influence of high voltage power system on metallic structures(gas pipeline, oil pipeline and water pipeline etc.). Therefore, we analyze the interference problems when the gas pipeline is buried with power cable in the same submarine tunnel. This paper present the results of the study about interference mechanism, AC corrosion limitation of safety voltage and analysis of induction voltage.

• The KIPS Transactions:PartC
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• v.15C no.1
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• pp.1-8
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• 2008

The security of wireless sensor networks is a challenging research area where the resources constraints are a bottleneck for any successful security design. Due to their computational feasibility, symmetric key algorithms that require key pre-distribution are more desirable for use in these networks. In the pre-distribution scheme, keys or keying materials are assigned to each node prior deployment to guarantee a secure communication within the entire network. Though several works are introduced on this issue, yet the connectivity and resiliency are imperfectly handled. In this paper, we revisit the grid based key pre-distribution scheme aiming to improve the connectivity, introduce a higher resiliency level, simplify the logic of key establishment and maintain same level of used of resources usage. The core of our modification relies on introducing the novel plat-based polynomial assignment and key establishment mechanism. To demonstrate the advantageous properties of our scheme over the revisited one, details of consumed resources, resulting connectivity, security and comparisons with relevant works are introduced.

• The Journal of Pediatrics of Korean Medicine
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• v.22 no.1
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• pp.13-24
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• 2008

Objectives This study was designed to analyze the clinical studies on Mental retardation(MR) in traditional Chinese medicine(TCM). Methods For this study, we searched the clinical studies on MR, which had been published from 2003 to 2007, through web site CNKI(中國知識基礎設施工 http://www.cnki.net). There were 17 clinical studies and we focused on those studies. Results 1. In those Chinese studies, they used following words to describe Mental retardation; 小人弱智($xi\check{a}o\acute{e}rru\grave{o}zh\grave{i}$), 智能發育不全($zh\grave{i}n\acute{e}ngf\bar{a}y\grave{u}buqu\acute{a}n$), 智力低下($zh\grave{i}l\grave{i}d\bar{i}xi\grave{a}$), 精神發育遲滯($j\bar{i}ngsh\acute{e}f\bar{a}y\grave{u}ch\acute{i}zh\grave{i}$), 智能落后($zh\grave{i}n\acute{e}nglu\grave{o}h\grave{o}u$), 智能落后($zh\grave{i}n\acute{e}ngch\acute{i}hu\check{a}n$), 失天愚型患人($xi\bar{a}nti\bar{a}ny\acute{u}x\acute{i}nghu\grave{a}n'\acute{e}r$). 2. There were many kinds of TCM treatment methods for MR, such as herbal medicine, acupuncture, electroacupunture, acupoint injection, Chuna therapy, and special education. And those TCM treatments methods showed higher efficacies in the treatment of MR compared with Western medicine. 3. Mental retardation was related with the deficiency of heart, kidney, liver, spleen(心虛, 腎虛, 肝虛, 脾虛) and the pathological mechanism of Phlegm(絹) and Blood stasis(慫沂)in the studies about the Bian Zheng-the types of differential diagnosis- of MR. 4. Most of studies used Intelligence Quotient(IQ) to assess the efficacy of TCM treatment of MR. And the duration of treatment, the degree of illness, the age of patient, and the cause of illness affected the prognosis of MR. Conclusions These results suggest that traditional medicine could be one of the useful treatments on MR. And these results could be used in the clinical practices and studies on MR in Korea.

• Biomolecules & Therapeutics
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• v.25 no.3
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• pp.249-258
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• 2017

To examine the effect of biflorin, a component of Syzygium aromaticum, on memory deficit, we introduced a scopolamine-induced cognitive deficit mouse model. A single administration of biflorin increased latency time in the passive avoidance task, ameliorated alternation behavior in the Y-maze, and increased exploration time in the Morris water maze task, indicating the improvement of cognitive behaviors against cholinergic dysfunction. The biflorin-induced reverse of latency in the scopolamine-treated group was attenuated by MK-801, an NMDA receptor antagonist. Biflorin also enhanced cognitive function in a naïve mouse model. To understand the mechanism of biflorin for memory amelioration, we performed Western blot. Biflorin increased the activation of protein kinase C-${\zeta}$ and its downstream signaling molecules in the hippocampus. These results suggest that biflorin ameliorates drug-induced memory impairment by modulation of protein kinase C-${\zeta}$ signaling in mice, implying that biflorin could function as a possible therapeutic agent for the treatment of cognitive problems.

• Earthquakes and Structures
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• v.13 no.6
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• pp.519-529
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• 2017

The surrounding rocks of underground openings are natural materials and their mechanical behavior under seismic load is different from traditional man-made materials. This paper proposes a framework to comprehensively model the mechanical behavior of surrounding rocks. Firstly, the effects of seismic load on the surrounding rocks are summarized. Three mechanical effects and the mechanism, including the strengthening effect, the degradation effect, and the relaxation effect, are detailed, respectively. Then, the framework for modelling the mechanical behavior of surrounding rocks are outlined. The strain-dependent characteristics of rocks under seismic load is considered to model the strengthening effect. The damage concept under cyclic load is introduced to model the degradation effect. The quantitative relationship between the damage coefficient and the relaxation zone is established to model the relaxation effect. The major effects caused by seismic load, in this way, are all considered in the proposed framework. Afterwards, an independently developed 3D dynamic FEM analysis code is adopted to include the algorithms and models of the framework. Finally, the proposed framework is illustrated with its application to an underground opening subjected to earthquake impact. The calculation results and post-earthquake survey conclusions are seen to agree well, indicating the effectiveness of the proposed framework. Based on the numerical calculation results, post-earthquake reinforcement measures are suggested.

• Geomechanics and Engineering
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• v.22 no.5
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• pp.449-460
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• 2020

The double-lane arrangement model is frequently used in underground coal mines because it is beneficial to improve the mining efficiency of the working face. When the double-lane arrangement is used, the service time of the reserved roadway increases by twice, which causes several difficulties for the maintenance of the roadway. Given the severe non-uniform deformation of the reserved roadway in the Buertai Coal Mine, the stress distribution law in the mining area, the failure characteristics of roadway and the control effect of support resistance (SR) were systematically studied through on-site monitoring, FLAC 3D numerical simulation, mechanical model analysis. The research shows that the deformation and failure of the reserved roadway mainly manifested as asymmetrical roof sag and floor heave in the region behind the working face, and the roof dripping phenomenon occurred in the severe roof sag area. After the coal is mined out, the stress adjustment around goaf will happen to some extent. For example, the magnitude, direction, and confining pressure ratio of the principal stress at different positions will change. Under the influence of high-stress rotation, the plastic zone of the weak surrounding rock is expanded asymmetrically, which finally leads to the asymmetric failure of roadway. The existing roadway support has a limited effect on the control of the stress field and plastic zone, i.e., the anchor cable reinforcement cannot fully control the roadway deformation under given conditions. Based on obtained results, using roadway grouting and advanced hydraulic support during the secondary mining of the panel 22205 is proposed to ensure roadway safety. This study provides a reference for the stability control of roadway with similar geological conditions.

• Structural Engineering and Mechanics
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• v.72 no.2
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• pp.169-180
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• 2019

The underlying mechanism of the wind-induced vibration of the hangers of the suspension bridges is still not fully understood at present and hence is comprehensively examined in this study. More specifically, a series of field measurements on the No. 2 hanger of the Xihoumen Bridge was first carefully conducted. Large amplitude vibrations of the hanger were found and the oscillation amplitude of the leeward cable was obviously larger than that of the windward cables. Furthermore, the trajectory of the leeward cable was close to an ellipse, which agreed well with the major characteristics of wake-induced vibration. Then, a theoretical model for the wake-induced vibration based on a 3-D continuous cable was established. To obtain the responses of the leeward cable, the finite difference method (FDM) was adopted to numerically solve the established motion equation. Finally, numerical simulations by using the structural parameters of the No. 2 hanger of the Xihoumen Bridge were carried out within the spatial range of $4{\leq}X{\leq}10$ and $0{\leq}Y{\leq}4$ with a uniform interval of ${\Delta}X={\Delta}Y=0.25$. The results obtained from numerical simulations agreed well with the main features obtained from the field observations on the Xihoumen Bridge. This observation indicates that the wake-induced vibration might be one of the reasons for the hanger oscillation of the suspension bridge. In addition, the effects of damping ratio and windward cable movement on the wake-induced vibration of the leeward cable were numerically investigated.