• Title/Summary/Keyword: 매개기관

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Pharmacokinetics of Sultadiazine/Trimethoprim from Bronchial Secretion in Pigs. (돼지의 기관분비에서 Sulfadiazine과 Trimethoprim의 약물동태학)

  • 김길수;윤효인
    • Journal of Veterinary Clinics
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    • v.14 no.1
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    • pp.42-47
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    • 1997
  • 돼지의 호흡기감염은 양돈산업에서 과밀한 사육으로 인하여 발생되는 주요한 질환중의 하나이다. 호흡기감염을 일으키는 병원체들은 주로 기관분비물과 점액에 상주하는 것으로 알려져 있다. 그러므로 호흡기감염의 치료를 위하여 기관분비물내에 항균약제의 농도는 적절하게 유지되어져야 한다. sulfadiazine(SDZ)과 trimethoprim(TMP)의 혼합제제는 전세계적으로 돼지의 호흡기감염의 치료에 널리 사용되어지고 있으나, 기관분비물에서 약물의 동태학적 특성에 관한 연구는 거의 찾아 볼 수가 없었다. 본 연구는 돼지의 좌측전대정맥으로 SDZ/TMP혼합제제를 일회 투여한 후 형성되는 약물동태학적 매개변수를 알아보기 위하여 실시되었다. 혈장과 기관분비물에서 SDZ/TMP농도는 HPLC (High Performance Liquid Chromatography)로 측정하여 약물동태학적 매개변수를 산출하였다. 혈장에서 SDZ와 TMP의 약물동태학적 매개변수는 2-compartment 와 1-compartment모델에 적합하였다. 혈장내 TMP의 반감기(0.90$\pm $0.06시간)가 SDZ(7.25$\pm $1.09시간)에 비하여 매우 짧은 점이 주요한 차이점으로 볼 수 있었으며, 더욱이 투여후 8시간이후에서는 측정이 되지 않았다. 기관분비물에서 SDZ의 농도는 전체 실험기간(0.5∼32시간)동안 거의 일정하게 유지되었고, 16시간후에서는 혈장농도보다 높은 수준을 나타내었다. TMP농도는 투여후 2∼3시간에서 혈장농도보다 높게 유지되었다. 이러한 결과를 토대로 호흡기감염의 처치와 예방에 있어서 약물의 용량 및 투여빈도를 결정하는데 응용되어 질 수 있을 것이다.

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How the Ageism Influenced on Elder Abuse and the Mediating Effects of Counselling from Public Organizations :Focusing on Care Helpers Working at Elderly Long-term Care Institutions (노인차별이 노인학대에 미치는 영향과 공적기관상담의 매개효과 :노인장기요양기관 요양보호사를 대상으로)

  • Jin, Chul-Sook
    • The Journal of the Korea Contents Association
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    • v.15 no.10
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    • pp.193-204
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    • 2015
  • This study investigated how the ageism of geriatric care helpers influenced on elder abuse during their long-term care service for elderly, and analyzed the mediating effects of counselling from public organizations on the causal relationship between ageism and elder abuse. The data used in this study was collected from 627 of care helpers working at elderly long-term care institutions in Gyeongsangnam-do Province, using structured survey(or questionnaire), and analyzed by Baron and Kenny(1986)'s multiple regression method. Ageism has a meaningful influence on elder abuse and counselling from public organizations has meaningful mediating effect on the relationship between ageism and elder abuse. These results show that elder abuse according to ageism can be improved by counselling from public organizations and It presents some practical implications for ageism and counselling from public organizations.

금융기관 내부마케팅 요인이 조직몰입과 고객지향성에 미치는 영향에 관한 연구

  • Kim, Jeong-Geun;Ha, Gyu-Su
    • 한국벤처창업학회:학술대회논문집
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    • 2016.04a
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    • pp.242-252
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    • 2016
  • 이 연구의 목적은 금융기관에서 실시하고 있는 내부마케팅 요인이 조직몰입과 고객지향성에 미치는 영향과 이들 요인들 간의 상관관계, 영향관계, 매개효과 등을 실증적으로 연구 분석하는 데 있다. 그동안 내부마케팅에 대한 연구는 여행사, 항공사, 호텔, 요식업 등 서비스산업 종업원을 대상으로 한 연구가 대부분이었으며, 금융기관에 대한 연구는 거의 미미한 편이었다. 특히 저금리시대와 인터넷전문은행의 신설 예고 등 금융환경의 급격한 변화에 따라 최근 금융기관들은 대고객 서비스 의 중요성을 인식하고 은행원에 대한 직무능력 향상과 사기진작을 위한 다양한 내부경영전략을 확대하고 있어, 이에 대한 연구는 필요하다고 판단된다. 이에 본 연구는 금융기관의 내부마케팅 요인으로 권한위임, 경영층지원, 의사소통, 팀웍역량을 주요 구성 요인으로 보고, 이들 요인들이 은행원의 조직몰입을 높이고, 나아가서는 고객지향성에 영향을 미칠 것이라는 전제로 실증분석을 하였다. 그 결과 내부마케팅 요인 중, 권한위임, 경영층지원, 팀웍역량은 조직몰입에 유의한 영향을 미치고 있으나, 의사소통은 조직몰입에 유의한 영향을 미치지 않는 것으로 나타났다. 또한 조직몰입이 고객지향성에 직접적으로 유의한 영향을 미치고 있으나, 조직몰입이 내부마케팅 요인과 고객지향성의 관계에서는 부분적인 매개효과가 있는 것으로 나타났다.

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The Relationship between the Emotional Labor and the Job Satisfaction of Workers in Senior Employment Agencies: Mediating Effect of Self-efficacy (노인일자리전담기관 종사자의 감정노동과 직무만족의 관계: 자기효능감의 매개효과)

  • Lee, Byoung-Rock
    • Journal of Digital Convergence
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    • v.19 no.12
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    • pp.463-468
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    • 2021
  • This paper verified the relationship between the emotional labor and the job satisfaction of workers in senior employment agencies. And this paper verified the mediating effect of self-efficacy between the both variables. We conducted a survey of 261 employees of the 21 agencies in Daejeon and Chungcheong area. According to the analysis : 1) employees' emotional labor influenced job satisfaction negatively. 2) the self-efficacy mediated between emotional labor and job satisfaction. As a result, we need to establish a management system for emotional labor, to carry out a crisis intervention of prompt therapy, and to provide education to cope with emotional labor for decreasing the emotional labor. It is important to lower the proportion of irregular workers, to improve the level of treatment, and cultivate self-leadership for promoting self-efficacy.

The Relationship between the Emotional Labor and the Organizational Commitment of Employees in Senior Employment Agencies : Mediating Effect of Self-efficacy (노인일자리전담기관 종사자의 감정노동과 조직몰입 : 자기효능감의 매개효과)

  • Lee, Byoung-Rock
    • Journal of the Korea Convergence Society
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    • v.12 no.12
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    • pp.349-354
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    • 2021
  • This study made an analysis of the relationship between the emotional labor and the organizational commitment and the mediating effect of job satisfaction of employees in senior employment agencies. A survey of 253 employees in Daejeon and Chungcheong areas was conducted. The important analysis methods are confirmatory factor analysis and bootstrap verification. The analysis results are employees' emotional labor had a negative effect on organizational commitment and the mediating effect of self-efficacy was proved significantly. For reducing emloyees' emotional labor, it is important to offer guidelines for improvement of emotional labor, regular inspection and education, and the proper measures of the administrators. To advance their self-efficacy, we need to offer education for the improvement of practice-based professionalism, education and administrative support to improve ethical consciousness, and appropriate emotional support service.

Structural Relationship Between Maternal Parenting Stress, Marital Communication, and School Adaptation in Early Childhood of Young Children (어머니의 양육스트레스와 부부 간 의사소통, 유아의 유아교육기관 적응 간의 구조적 관계)

  • Noh, Min Ja;Song, Mi Jeoung
    • Korean Journal of Child Education & Care
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    • v.19 no.3
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    • pp.115-128
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    • 2019
  • Objective: The purpose of this study is to investigate the effects of maternal parenting stress on early childhood adaptation and to verify the mediating effect of marital communication in the adaptation of young children to early education institution. Methods: The subjects of this study are 219 infants and their mother living in J city in Jeonbuk province. The data collected in this study were analyzed as spss 21.0 and amos 21.0, and the mediating effect was verified through structural equation modeling. Results: The results of this study are as follows: First, maternal parenting stress and marital communication have a direct influence on the adaptation of young children to early childhood education institution. Second, marital communication showed mediating effect on the relationship between maternal parenting stress and the adaptation of early childhood education institution. Based on these results. Conclusion/Implications: We discussed the importance of reduction of parenting stress and positive interpersonal communication between couples.

The Relationship between Collaboration with External Institution and New Product Sales of SMEs: The Role of Technological Innovation and Marketing Capability (중소기업의 외부기관 협력과 신제품 매출 간의 관계: 기술혁신과 마케팅 역량의 역할)

  • Lee, Sang-Won;Shin, Jin-Kyo;Yeo, Kyung-Hwan
    • Korean small business review
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    • v.41 no.3
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    • pp.77-94
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    • 2019
  • The study examined the effect of collaboration with external institution on new product sales, the mediating effects of technological innovation, and the moderating effect of marketing capability. The results showed that external collaboration with external institution has a significant impact on new product sales in the R&D field of SMEs, and technological innovation plays a mediating role in the relationship between collaboration with external institution and new product sales. Also, the effect of marketing capability in the relationship between technological innovation and new product sales was also significant. Finally, the mediating effect of technological innovation between collaboration with external institution and new product sales was moderated by marketing capability.

Effects of Job Stress on Turnover among Counselors in National Protection Agencies for the Elderly(NPAE): Focused on Mediated Effect of Working Environment (노인보호전문기관 상담원들의 직무스트레스가 이직의도에 미치는 영향: 업무환경의 매개효과를 중심으로)

  • Kim, Mincheol;Hur, Junsoo
    • The Journal of the Korea Contents Association
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    • v.21 no.5
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    • pp.384-397
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    • 2021
  • This study seeks to dertermine the influence and mediating effect of work environments among counselors at National Protection Agencies for Elderly(NPAE), who are conducting elderly abuse prevention service when domestic and facility abuse is augmenting due to social distancing as a result of COVID-19, on turnover intention. This study ultimately applied the analysis of 290 replies to surveys that were distributed to 306 workers at a total of 34 National Protection Agencies for Elderly(NPAE). The nationwide investigation was carrid out from 1st July until 30th July, 2020. SPSS 23.0 was used for the analysis and the Sobel-Test was conducted to verify the multiple regression analysis and significance. This was for the confirmation of descriptive statistics, correlation analysis and mediation effect so that the influence and relationships of variables could be verified. The results are as follows. First the job stress of counselors in the NPAE had a positive effect on turnover intention. Second, the work environment of the NPAE was found to have a negative influence on turnover intention. Third, the work environment played a significant partially mediating role in the relation between the job stress and turnover intention among the counselors. Based on such research results, policy and practical implications to reduce the stress, improve the work environment and reduce turnover of counselors in the NPAE were presented.

The Effect of Medical Institution's Corporate Social Responsibility on Organization and Management Performance (의료기관의 사회적 책임이 조직성과와 경영성과에 미치는 영향)

  • Choi, Kwan-Bong;Kim, Jeong-Kyo;Kim, Hye-Ri
    • Journal of the Korea Convergence Society
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    • v.8 no.10
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    • pp.239-248
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    • 2017
  • The empathy for the corporate social responsibility(CSR) is rapidly expanding around the global company, its range having already spread to the whole world, and CSR activities are actively being carried out. Recently, CSR of the medical institution is not selectively accommodated and applied, but is perceived as a basic capacity and responsibility for sustainable growth and development of medical institution. In this study, the effect of social responsibility of medical institutions on the management performance and organization performance was analyzed. It can be seen that there is a need for a strategy utilizing CSR and organization performance in order to accomplish management goal which is the ultimate output of the organization. It is expected that this study contributes to study related to medical institution CSR as well as suggest a strategy direction through CSR.