• 한국자기공명학회논문지
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• 제18권1호
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• pp.36-40
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• 2014

Predicting secondary structure of protein through assigned backbone chemical shifts has been used widely because of its convenience and flexibility. In spite of its usefulness, chemical shift based analysis has some defects including isotopic shifts and solvent interaction. Here, it is shown that corrected chemical shift analysis for secondary structure of protein. It is included chemical shift correction through consideration of deuterium isotopic effect and calculate chemical shift index using probability-based methods. Enhanced method was applied successfully to one of the proteins from Mycobacterium tuberculosis. It is suggested that correction of chemical shift analysis could increase accuracy of secondary structure prediction of protein and small molecule in solution.

• 응용통계연구
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• 제25권3호
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• pp.465-470
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• 2012

EWMA(exponentially weighted moving average) charts and CUSUM(cumulative sum) charts are very effective to detect small shifts in the process mean. These charts have some control-chart parameters that allow the charts and be tuned and be more sensitive to certain shifts. The EWMA chart requires users to specify the value of a smoothing parameter, which can also be designed for the size of the mean shift. However, the size of the mean shift that occurs in applications is usually unknown and EWMA charts can perform poorly when the actual size of the mean shift is significantly different from the assumed size. In this paper, we propose the design procedure to find the optimal smoothing parameter of the EWMA chart when the size of the mean shift is unknown.

• 한국경영과학회지
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• 제20권3호
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• pp.123-146
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• 1995

Several quality control schemes have been extensively compared using multivariate normal data sets simulated with various correlation structures. They include multiple univariate CUSUM charts, multivariate EWMA charts, multivariate CUSUM charts and Shewhart T$^{3}$ chart. This paper considers a new approach of the multivariate EWMA chart, in which the smoothing matrix has full elements instead of only diagonal elements. Performance of the schemes is measured by avaerage run length (ARL), coefficient of variation of run length (CVRL) and rank in order of signaling of off-target shifts in the process mean vector. The schemes are also compared by noncentrality parameter. The multiple univariate CUSUM charts are generally affected by the correlation structure. The multivariate EWMA charts provide better ARL performance. Especially, the new EWMA chart shows remarkable results in small shifts.

• 산업경영시스템학회지
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• 제33권3호
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• pp.146-153
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• 2010

When the production run is short and process parameters change frequently, it is difficult to monitor the process using traditional control charts. In such a case, the coefficient of variation (CV) is very useful for monitoring the process variability. The CV control chart is an effective tool to control the mean and variability of process simultaneously. The CV control chart, however, is not sensitive at small shifts in the magnitude of CV. The CV-EWMA(exponentially weighted moving average) control chart which was developed recently is effective in detecting a small shifts of CV. Since the CV-EWMA control chart scheme can be viewed as a weighted average of all past and current CV values, it is very sensitive to small change of mean and variability of the process. In this paper, we propose an FIR(Fast initial response) CV-EWMA control chart to improve the sensitivity of a CV-EWMA scheme at process start-up or out-of-control process. Moreover, we suggest the values of design parameters and show the results of the performance study of FIR CV-EWMA control chart by the use of average run length(ARL). Also, we compared the performance of FIR CV-EWMA control chart with that of the CV-EWMA control chart and we found that the CV-EWMA control chart gives longer in-control ARL and much shorter out-of-control ARL.

• 통합자연과학논문집
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• 제5권4호
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• pp.246-252
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• 2012

Multivariate cumulative sum (CUSUM) control charts for simultaneously monitoring both means and variances under multivariate normal process are investigated. Performances of multivariate CUSUM schemes are evaluated for matched fixed sampling interval (FSI) and variable sampling interval (VSI) features in terms of average time to signal (ATS), average number of samples to signal (ANSS). Multivariate Shewhart charts are also considered to compare the properties of multivariate CUSUM charts. Numerical results show that presented CUSUM charts are more efficient than the corresponding Shewhart chart for small or moderate shifts and VSI feature with two sampling intervals is more efficient than FSI feature. When small changes in the production process have occurred, CUSUM chart with small reference values will be recommended in terms of the time to signal.

• Journal of the Korean Data and Information Science Society
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• 제13권2호
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• pp.21-29
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• 2002

Several different control statistics to simultaneously monitor dispersion matrix of several quality variables are presented since different control statistics can be used to describe variability. Multivariare cumulative sum (CUSUM) control charts are proposed and the performances of the proposed CUSUM charts are evaluated in terms of average run length (ARL). Multivariate Shewhart charts are also proposed to compare the properties of the proposed CUSUM charts. The numerical results show that multivariate CUSUM charts are more efficient than multivariate Shewhart charts for small or moderate shifts. And we also found that small reference value of the CUSUM chart is more efficient for small shift.

• 전자공학회논문지D
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• 제35D권4호
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• pp.84-92
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• 1998

A program was developed to analyze the electrical characteristics and harmonic distrotion in a two-dimensional silicon BJT. The finite difference equations of the small signal and its second and thired harmonics for basic semiconductor equations are formulated treating the nonlinearity and time dependence with Volterra series and Taylor series. The soluations for three sets of simultaneous equations were obtained sequantially by a decoupled iteration method and each set was solved by a modified Stone's algorithm. Distortion magins and ac parameters such as input impedance and current gains are calculated with frequency and load resistance as parameters. The distortion margin vs. load resistancecurves show cancellation minima when the pahse of output voltage shifts. It is shown that the distortionof small signal characteristics can be reduced by reducing the base width, increasing the emitter stripe length and reducing the collector epitaxial layer doping concentration in the silicon BJT structure. The simulation program called TRADAP can be used for the design and optimization of transistors and circuits as well as for the calculation of small signal and distortion solutions.

• 대한안전경영과학회:학술대회논문집
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• 대한안전경영과학회 2005년도 추계학술대회
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• pp.93-100
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• 2005

Small & medium sized company is the most efficient way of management to prevent my accident in the area of industry. Employees are more than 30 to less than 50 persons and which is liable for securing a safety manager on site, is gradually seen on the surface. Even a small company is nothing less than a dead zone from a safety since it's free from his obligation of employing a safety manager. Let us now think about the effective measures against a industrial accident by collecting, reviewing a variety of preventive measures, which is being carried out for preventing an industrial accident happening in a small company, and comparing, analyzing the effect according to the respective measures. Through this research, it's expected to contribute to both the development of small & medium sized company and our national economy with the improvement of a company's competitiveness and the accumulation a technical background by way of prevention from occurring industrial accident in a small & medium sized company, in accordance with an friendly environment of work room to protect the employee from leaving his job.

• 품질경영학회지
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• 제22권1호
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• pp.66-81
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• 1994

Several sample statistics to simultaneously monitor both means and variances for multivariate quality characteristics under multivariate normal process are proposed. Performances of multivariate Shewhart schemes and cumulative sum(CUSUM) schemes are evaluated for matched fixed sampling interval(FSI) and variable sampling interval(VSI) feature. Numerical results show that multivariate CUSUM charts are more efficient than Shewhart charts for small or moderate shifts and VSI feature is more efficient than FSI feature.

• Communications for Statistical Applications and Methods
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• 제4권3호
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• pp.715-723
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• 1997

Multivariate control statistics to simultaneously monitor both means and variances for several quality variables under multivariate normal process are proposed. Performances of the proposed multivariate charts are evaluated in terms of average run length(ARL). Multivariate Shewhart chart is also proposed to compare the performances of multivariate exponentially weighted moving average(EWMA) charts. A numerical comparison shows that multivariate EWMA charts are more efficient than multivariate Shewhart chart for small and moderate shifts and multivariate EWMA scheme based on accumulate-combine approach is more efficient than corresponding multivariate EWMA chart based on combine-accumulate approach.