• 한국식품영양학회지
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• 제25권4호
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• pp.747-754
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• 2012

The objective of this study was to investigate free amino acid composition, antioxidant activity, alcohol dehydrogenase activity and the sensory quality attributes for the development of functional soy sauce using Hutgae (Hovenia dulcis Thunb) fruit, which is well-known for improving liver function and alleviating various negative physiological effects following heavy consumption of alcoholic beverages. Soy sauces adding six types of extract from Hutgae fruit (HF) were prepared (SSH1: HF 20%, SSH2: HF 10%, SSH3: HF 20%/40 days NaCl extract, SSH4: HF 20%/20 days NaCl extract, SSH5: HF 20% water bath extract, SSH6: freeze-drying powder from HF 20% aqueous extract), compared with soy sauce using the conventional method. These soy sauces were used for determining alcohol dehydrogenase activity by NADH absorbance, the antioxidant effect by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and sensory evaluation by sensory scaling. Total free amino acid contents for most samples were in the range of 327.3 to 375.5 mg%, and then, aspartic acid and glutamic acid content of SSH1 and SSH5 were higher than that of others. DPPH radical scavenging activity was shown to be the highest in SSH4, also SSH1, SSH5 and SSF6 were shown to be higher than the control group. Alcohol dehydrogenase activity was shown to be the highest in SSH5. In sensory evaluation, the highest intensity of roast smell was observed in SSH4 while sweet taste was shown to be the highest in SSH5, and SSH3 and SSH5 revealed higher overall acceptability. From these results, Hutgae fruit soy sauces demonstrated antioxidant activity and alcohol dehydrogenase activity. In conclusion, soy sauces containing the water bath extract of Hutgae fruit may be used as a functional seasoning.

• 대한한방내과학회지
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• 제41권5호
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• pp.787-799
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• 2020

Objectives: Pityriasis rubra pilaris (PRP) is a rare papulosquamous disorder with unknown etiology. Studies on adults have not been conducted yet in Korean medicine. We report the progress of Korean medicine treatment for adult-type pityriasis rubra pilaris. Methods: A 62-year-old female patient was diagnosed with PRP in June 2019. After the diagnosis of PRP, retinoid treatment was continued for about 6 months, and then the drug was switched to an oral immunosuppressant. However, the patient's symptoms did not improve, but instead worsened. The patient was treated with Mihudeungsikjang-tang and acupuncture therapy. We evaluated her treatment progress based on the Dermatology Life Quality Index (DLQI), a visual analogue scale (VAS), and the changes in the patient's subjective symptoms. Results: After Korean medicine treatment, the DLQI and VAS scores improved from 18 points to 16 points and from 6 points to 4 points, respectively. The whole-body itching and scaling were reduced by 30% compared to pretreatment. The itching and pain in the neck, which had been severely symptomatic, decreased by 50%. The pain and dysesthesia in the upper and lower extremities disappeared, but the erythema still remained. Conclusions: Conventional treatments for PRP have limitations due to adverse effects and difficulty in treating refractory forms. Korean medicine treatment is worth considering as it can complement the limitations of conventional treatments, although more studies will be needed.

• 한국HCI학회:학술대회논문집
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• 한국HCI학회 2009년도 학술대회
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• pp.402-405
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• 2009

차세대 출판문인 디지로그 북은 기존 서적과 디지털콘텐츠를 통합하여 사용자에게 아날로그적 감성과 디지털오감을 제공한다. 이러한 디지로그 북을 제작하기 위해 디지로그 북의 저작도구에 대한 연구가 진행 중이며, 본 논문에서는 디지로그 북에 사용될 콘텐츠를 저작하는 활동에서 시각과 청각에만 의존한 작업을 보다 실감 있도록 하기 위해 펜형 햅틱 사용자인터페이스를 개발하고자 하였다. 햅틱 사용자인터페이스는 디지로그 북을 저작하는 작업에서 3차원 작업공간에서 공간상에 배치되는 3차원 객체를 이동, 회전, 크기 변경 및 메뉴선택 버튼의 클릭등과 같은 다양한 작업에서 각 작업을 보다 실감 있게 하기 위한 진동 햅틱 효과를 사용자에게 제공한다. 본 연구에서는 이러한 디지로그 북의 저작 환경에 적합한 사용자인터페이스의 외형, 회로 설계, 진동패턴의 설계/내장 및 저작시스템과의 연동을 위한 프로토콜을 정의하고 이렇게 개발된 햅틱 사용자인터페이스를 사용하여 사용자평가를 간단히 실시하였다. 디지로그 북 저작 작업에서 이렇게 개발된 햅틱 인터페이스의 촉각 효과를 시청각정보와 함께 사용함으로써 디지로그 북 저작 작업을 보다 효과적으로 할 수 있기를 기대한다.

• 한국초등과학교육학회지:초등과학교육
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• 제34권4호
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• pp.458-475
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• 2015

The purpose of this study was to analyze the responses of pre-service elementary teachers to the plant learning using plant-observation activities and observation journal writings. Thirty pre-service teachers participated in this study. Before and after practicing plant observation and observation journal writing for 11 weeks, pre-service teachers' interest to plants, attitude to plant-observation teaching, and plant-observation teaching efficacy were examined using a questionnaire. Also, the observation journals, reflective journal writings, and interviews were analyzed to investigate their qualitative change. In addition, the pre-service teachers were classified by multi-dimensional scaling and cluster analysis with respect to attitude to plant-observation teaching and observation journal writing, and teaching efficacy. While the pre-service teachers showed significant increase of the interest to plants and plant-observation teaching efficacy, and positive change of the attitude to plant-observation teaching, there was a little difference between gender with more positive effects on females. The positive attitude changes of pre-service teachers included positive recognition about plants and the diversity, increased interest and curiosity about plants, careful observation about nearby plants, and independent learning and positive inquiry with plants. In terms of teaching efficacy, they showed positive change such as enjoyment and satisfaction with plant-observation, confidence as elementary teachers in the future, and recognition about the importance of elementary teachers for plant education. However, the changes were different among the groups classified by attitude to plant-observation teaching and observation journal writings, and plant-observation teaching efficacy.

• 한국산업정보학회논문지
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• 제19권1호
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• pp.61-67
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• 2014

센서 시스템과 같은 저전력 설계를 요구하는 시스템에서 기존의 동기방식의 회로는 낮은 전압에서 지연(delay)이 급격히 증가하여 시스템의 전체 성능을 유지할 수 없을 뿐만 아니라, 공정, 전압, 온도 변이 (PVT variation), 노화 등에 크게 영향을 받아서 올바른 동작을 기대할 수 없다. 따라서, 신뢰할 수 있는 초저전력 설계에서 비동기 회로가 스케일링 이슈를 해결할 수 있는 방법으로 최근 다시 고려되고 있다. 그러나, 디지털 시스템에서 동기회로를 NCL 회로로 모두 대체하는 것은 쉽지가 않기때문에 동기회로와 비동기 회로 사이의 연결이 꼭 필요하다. 본 논문에서는 동기회로와 비동기 회로를 연결할 수 있는 새로운 설계방법을 보이고, 0.18um 공정기술을 사용한 $4{\times}4$ 곱셈기를 사용해서 검증을 하였다.

• 한국정보통신학회논문지
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• 제19권3호
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• pp.581-586
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• 2015

본 연구에서는 비대칭 이중게이트 MOSFET의 채널길이와 채널두께의 비에 따른 문턱전압이하 스윙의 변화를 분석하고자한다. 비대칭 이중게이트 MOSFET는 상하단 게이트 구조를 달리 제작할 수 있어 단채널효과를 제어할 수 있는 요소가 증가한다는 장점이 있다. 특히 채널길이를 감소하였을 경우 문턱전압이하 스윙의 급격한 증가로 인한 특성저하 현상을 감소시킬 수 있다. 그러나 스켈링 이론에 따라 채널길이 감소에 따라 채널두께도 변화되어야하며 이에 문턱전압이하 스윙이 변화하게 된다. 그러므로 채널길이와 채널두께의 비가 문턱전압이하 스윙을 결정하는 중요 요소가 된다. 해석학적으로 문턱전압이하 스윙을 분석하기 위하여 해석학적 전위분포를 포아송방정식을 통하여 유도하였으며 다양한 채널길이 및 채널두께에 대하여 전도중심과 문턱전압이하 스윙을 계산한 결과 채널길이와 채널두께의 비에 따라 전도중심과 문턱전압이하 스윙이 변화한다는 것을 알 수 있었다.

• 대한의용생체공학회:의공학회지
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• 제27권6호
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• pp.323-331
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• 2006

The purpose of this study was to investigate the effect of performing a cognitive task during treadmill walking on the stride rate variability. Ten university students(age $24.0{\pm}0.25$, height $172{\pm}3.1cm$, weight $66{\pm}5.3kg$) were participated in dual task experiments which consist of both walking alone and walking with a cognitive task. Two-back task was selected for the cognitive task since it did not have learning effect during the experimental procedure.3D motion analysis system was used to measure subject's position data by changing walking speed with 4.8, 5.6, 6.4, 6.8, and 7.2 km/hr. Stride rate was calculated by the time between heel contact and heel contact. Accuracy rate of a cognitive task during walking, coefficient of variance, allometric scaling methods and Fano factor were used to estimated the stride rate variability. As the walking speed increased, accuracy rate decreased and the logarithmic value of Fano factor increased which showed the statistical difference. Thus it can be concluded that the gait control mechanism is distracted by the secondary attention focus which is the cognitive task ie. two-back task. Further study is needed to clarify this by increasing the number of subject and experiment time.

• 한국도로학회논문집
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• 제20권2호
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• pp.19-25
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• 2018

PURPOSES : This purpose of this study is to analyze the effect to autogenous shrinkage of the top-layer material of a two-lift concrete pavement mixing both silica fume and polymer powder. METHODS : The bottom-layer of a two-lift concrete pavement was paved with original portland cement (OPC) with a 20~23 cm thickness. Additionally, the top-layer which is directly exposed to the environment and vehicles was paved with a high-performance concrete (HPC) with a 7~10 cm thickness. These types of pavements can achieve a long service life by reducing joint damage and increasing the abrasion and scaling resistance. In order to integrate the different bottom and top layer materials, autogenous shrinkage tests were performed in this study according to the mixing ratio of silica fume and polymer powder, which are the admixture of the top-layer material. RESULTS : Autogenous shrinkage decreased when polymer powder was used in the mix. Contrary to this, autogenous shrinkage tended to rise with increasing silica fume content. However, the effects were not significant when small amounts of polymer powder were used (3% and 11%). CONCLUSIONS : The durability and compressive strength increase when silica fume is used in the mix. The flexural strength considerably increases and autogenous shrinkage of concrete decreases when polymer powder is used in the mix. As seen from above, the proper use of these materials improves not only durability, but also autogenous shrinkage, leading to better shrinkage crack control in the concrete.

• 한국재료학회:학술대회논문집
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• 한국재료학회 2011년도 춘계학술발표대회
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• pp.41.2-41.2
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• 2011

Recently, scaling down of ULSI (Ultra Large Scale Integration) circuit of CMOS (Complementary Metal Oxide Semiconductor) based electronic devices become much faster speed and smaller size than ever before. However, very narrow interconnect line width causes some drawbacks. For example, deposition of conformal and thin barrier is not easy moreover metallization process needs deposition of diffusion barrier and glue layer. Therefore, there is not enough space for copper filling process. In order to overcome these negative effects, simple process of copper metallization is required. In this research, Cu-V thin alloy film was formed by using RF magnetron sputter deposition system. Cu-V alloy film was deposited on the plane $SiO_2$/Si bi-layer substrate with smooth and uniform surface. Cu-V film thickness was about 50 nm. Cu-V layer was deposited at RT, 100, 150, 200, and $250^{\circ}C$. XRD, AFM, Hall measurement system, and XPS were used to analyze Cu-V thin film. For the barrier formation, Cu-V film was annealed at 200, 300, 400, 500, and $600^{\circ}C$ (1 hour). As a result, V-based thin interlayer between Cu-V film and $SiO_2$ dielectric layer was formed by itself with annealing. Thin interlayer was confirmed by TEM (Transmission Electron Microscope) analysis. Barrier thermal stability was tested with I-V (for measuring leakage current) and XRD analysis after 300, 400, 500, 600, and $700^{\circ}C$ (12 hour) annealing. With this research, over $500^{\circ}C$ annealed barrier has large leakage current. However V-based diffusion barrier annealed at $400^{\circ}C$ has good thermal stability. Thus, thermal stability of vanadium-based thin interlayer as diffusion barrier is good for copper interconnection.

• 한국환경보건학회지
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• 제39권6호
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• pp.492-504
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• 2013

Objectives: This analysis seeks to evaluate the impact of environmental health factors (EHF; e.g. hospital beds per capita, employees of medical institutions) on extreme-heat vulnerability assessment in Busan Metropolitan City during 2006-2010. Methods: According to the vulnerability concept suggested by the Intergovernmental Panel on Climate Change (IPCC), extreme-heat vulnerability is comprised of the categories of Exposure, Sensitivity, and Adaptive Capacity (including EHF). The indexes of the Exposure and Sensitivity categories indicate positive effects, while the Adaptive capacity index indicates a negative effect on extreme-heat vulnerability. Variables of each category were standardized by the re-scaling method, and then each regional relative vulnerability was computed with the vulnerability index calculation formula. Results: The extreme-heat vulnerability index (EVI) excepting EHF was much higher in urban areas than in suburban areas within the metropolitan area. When EHF was considered, the difference in the EVI between the two areas was reduced due to the increase of the Adaptive capacity index in urban areas. The low EVI in suburban areas was induced by a dominant effect of natural environmental factors (e.g. green area) within the Adaptive capacity category. Conclusions: To reduce the vulnerability to extreme heat in urban areas, which were more frequently exposed to extreme heat than others areas, public health and natural environments need to be improved in sensitive areas.