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Effects of Korean Medicinal Treatments Including Antaeeum-gamibang on Posterior Neck Pain and Lower Back Pain Caused by Traffic Accidents During Pregnancy: Five Case Reports (안태음(安胎飮) 가미방(加味方)과 한방치료를 병행한 임신 중 교통사고로 인한 경추 및 요추부 통증 환자 치험 5례)

  • Shin, Soo-Ji;Kim, Gil-Hwan;Ju, Yeong-Guk;Lee, So-Jin;Ahn, Sang-Min;Jeong, Jae-Joong
    • The Journal of Korean Obstetrics and Gynecology
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    • v.30 no.3
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    • pp.146-157
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    • 2017
  • Objectives: This study was performed to assess the effectiveness of Korean medicinal treatments including Antaeeum-gamibang on posterior neck pain and lower back pain caused by traffic accidents during pregnancy. Methods: Patients were treated by Antaeeum-gamibang, acupuncture and Chuna manual therapy. To measure treatment outcomes, Numerical rating scale (NRS), Oswestry disability index (ODI), Neck disability index (NDI), European Quality of Life-5 Dimensions (EQ-5d), and range of motion (ROM) were used. Results: After treatment, the average NRS of posterior neck pain significantly decreased from $4.20{\pm}1.30$ to $1.80{\pm}0.45$ and the average NRS of lower back pain significantly decreased from $6.40{\pm}1.14$ to $2.20{\pm}0.84$. ODI significantly decreased from $41.42{\pm}17.79$ to $28.29{\pm}14.69$, NDI significantly decreased from $34.93{\pm}9.85$ to $20.27{\pm}8.96$. EQ-5d and ROM improved at all cases. Conclusions: Korean Medicinal treatments including Antaeeum-gamibang may be effective in the treatment of posterior neck pain and lower back pain caused by traffic accidents during pregnancy. However, more case reports and studies are required to identify exactly what treatment is more efficient.

The Protective Effect of Green Tea Extract on Alpha-amanitin Induced Hepatotoxicity (알파 아마니틴에 의한 간독성에 대한 녹차 추출물의 보호 효과)

  • An, Su Hwan;Sun, Kyung Hoon;Hong, Ran;Lee, Byoung Rai;Park, Yongjin
    • Journal of The Korean Society of Clinical Toxicology
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    • v.17 no.2
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    • pp.58-65
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    • 2019
  • Purpose: Alpha-amanitin induces potent oxidative stress and apoptosis, and may play a significant role in the pathogenesis of hepatotoxicity. This study examined the mechanisms of α-amanitin-induced apoptosis in vitro, and whether green tea extract (GTE) offers protection against hepatic damage caused by α-amanitin (AMA) induced apoptosis in vivo. Methods: The effects of GTE and SIL on the cell viability of cultured murine hepatocytes induced by AMA were evaluated using an MTT assay. Apoptosis was assessed by an analysis of DNA fragmentation and caspase-3. In the in vivo protocol, mice were divided into the following four groups: control group (0.9% saline injection), AMA group (α-amanitin 0.6 mg/kg), AMA+SIL group (α-amanitin and silibinin 50 mg/kg), and AMA+GTE group (α-amanitin and green tea extract 25 mg/kg). After 48 hours of treatment, the hepatic aminotransferase and the extent of hepatonecrosis of each subject was evaluated. Results: In the hepatocytes exposed to AMA and the tested antidotes, the cell viability was significantly lower than the AMA only group. An analysis of DNA fragmentation showed distinctive cleavage of hepatocyte nuclear DNA in the cells exposed to AMA. In addition, the AMA and GTE or SIL groups showed more relief of the cleavage of the nuclear DNA ladder. Similarly, values of caspase-3 in the AMA+GTE and AMA+SIL groups were significantly lower than in the AMA group. The serum AST and ALT levels were significantly higher in the AMA group than in the control and significantly lower in the AMA+GTE group. In addition, AMA+GTE induced a significant decrease in hepatonecrosis compared to the controls when a histologic grading scale was used. Conclusion: GTE is effective against AMA-induced hepatotoxicity with its apoptosis regulatory properties under in vitro and in vivo conditions.

The Development of an Oral Care Protocol for Cancer Patients Receiving Chemotherapy and its Effects (항암화학요법을 받는 환자의 구강관리 프로토콜개발 및 적용효과)

  • Son, You Jin;Shin, Yoon Jung;Cho, Mee Young;Kim, Soon Ho;Park, Ok Sun;Han, Soo Young;Kang, Young Lynn;Kim, Yeon Woo;Song, Su Kyung;Lee, Sun Hwa;Hwang, In Hee;Son, Byung Hee;Joo, Un Hye;Kim, Sue;Choi, Hye Jin
    • Journal of Korean Clinical Nursing Research
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    • v.17 no.1
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    • pp.113-122
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    • 2011
  • Purpose: This study was conducted to develop and evaluate an oral care protocol for cancer patients receiving chemotherapy. Methods: The participants in this study were cancer patients in Severance hospital in Seoul. A total of 31 patients were assigned to the experimental group, and 29 patients to the control group. Data were collected from August 1 to October 5, 2010. The protocol included definition and symptom of oral mucositis, self-check method of oral status, prophylactic method of oral mucositis (oral care, eating habits, and gargling) and management of oral mucositis. Oral Assessment Guide (OAG) was used as the measurement tool of oral mucositis in this study, Oral Care Performance Scale was used as the measurement tool of oral care performance status. Data were analyzed with a $x^2-test$ and t-test, and repeated measures ANOVA, using SPSS/WIN 18.0 program. Results: Patients in the experimental group receiving the oral care protocol had a significant difference (t=-2.938, p=.005) in the oral care performance compared to the control group. However, there was no significant difference (F=1.255, p=.274) in the oral mucositis status between two groups. Conclusion: This study showed that the oral care protocol could improve oral care performance status for the patients under chemotherapy.

Analysis of the Impact of the Expansion of Direct Construction Works and Suggestions on the Application (직접시공 확대의 영향 분석 및 직접시공의무제도 적용을 위한 대응방안 제언)

  • Lee, Meesung;Kim, Siyeon;Yu, Ilhan;Han, Ju-yeon;Son, JeongWook
    • Korean Journal of Construction Engineering and Management
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    • v.22 no.6
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    • pp.15-23
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    • 2021
  • As the construction production system is reorganized as part of the construction industry innovation plan, direct construction is expanding. According to this trend, this study analyzed the impact and problems of the expansion of direct construction through the position of the construction industry and a study of foreign cases. In addition, by diagnosing the impact of the measures to expand direct construction from various aspects, countermeasures were suggested to suitably apply the direct construction mandatory system. Also, for each alternative, effects and problems were evaluated through interviews with experts in policy/administrative and architecture fields. The alternatives for expanding and improving the efficiency of the direct construction mandatory system derived from this study are four items: granting the discretion of the client, differentiation by scale of construction, utilization of construction guarantee system, and introduction of flexible working group leader system. As a result of the expert interview, all of them were evaluated to have a positive impact directly and indirectly on the expansion of direct construction. This study contributes literature to the application of the direct construction mandatory system by examining the current status of direct construction, and suggests a direction for expanding direct construction through deduction of alternatives for applying the direct construction mandatory system and expert evaluation.

Effect of Pressure Taping between Tibia and Fibula on Pain, ROM and Strength in Athletes diagnosed with High Ankle Sprain (원위경비인대결합 손상 선수의 경·비간 압박테이핑 적용이 통증, 관절가동범위, 근력에 미치는 영향)

  • Jang, Won-Bong;Oh, Jae-Keun;Yoon, Jin-Ho
    • Journal of the Korea Convergence Society
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    • v.12 no.4
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    • pp.303-310
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    • 2021
  • This study was conducted to identify the effects of pressure taping between tibia and fibula of High Ankle Sprain athletes on pain, Range of Motion(ROM), and strength and to provide basic data for rehabilitation programs. The subjects of the study were conducted with a total of 10 athletes except for four who gave up who were diagnosed with high ankle sprain, or who were diagnosed with ankle sprain but their physical examinations proved positive. The results showed no significant differences in pain(Visual Analog Scale, VAS). The ROM was significantly increased in inversion(IV) and eversion(EV) in both groups. The Isometric strength was significantly improved in IV(0°, 7°, 14°) and EV(0°) in Taping Group(TG). When taping was applied to athletes with injury to the High Ankle Sprain, ROM and muscle strength improved at the same pain level.

Effects of Scalp Myofascial Technique and Manual Therapy on Pain and Quality of Life in Tension Type Headache Patients : Six Month Follow-up Results (두피근막이완기법과 도수치료가 긴장성두통 환자의 통증과 삶의 질에 미치는 영향 : 6개월 추적연구)

  • Lee, Hwa-Gyeong;Kim, Seong-Yeol
    • Journal of The Korean Society of Integrative Medicine
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    • v.9 no.2
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    • pp.119-130
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    • 2021
  • Purpose : We aimed to validate a new manual therapy to treat tension type headache(TTH) by applying myofascial release techniques to the scalp and to examine the changes in the quality of life and the headache characteristics after treatment and at the 6-month follow-up. Methods : Thirty patients were recruited in this study and were assigned to two groups through simple random sampling. Fifteen patients were assigned to the manual therapy group (MT) and 15 patients to the scalp myofascial release technique (SMT) group. However, five patients from the MT group and one from the SMT group were excluded. Therefore, 24 patients with TTH (10 males, 14 females) participated in the study. Patients underwent either MT or SMT. The procedures were performed by a physical therapist twice per week for 4 weeks. The quality of life [using the brief pain inventory (BPI) and the headache impact test (HIT)], and the frequency, duration, and intensity of the headache [on a visual analog scale (VAS)] were assessed before and after the treatment, and at the follow-up. Results : After 4 weeks of SMT, the frequency (p<.001), duration (p<.05), and intensity (p<.001) of the headache and the quality of life (HIT; p <.001, BPI; p<.001) significantly improved in the patients with TTH. The improvement in these parameters remained significant even after 6 months of follow-up. Similarly, After 4 weeks of MT, the frequency (p<.05), duration (p<.05), and intensity (p<.01) of the headache, and the quality of life (HIT; p<.05, BPI; p<.001) significantly improved in the patients with TTH. The improvement in these parameters remained significant even after 6 months of follow-up. There was no significant difference in these parameters between the two groups. Conclusion : It has been suggested that MT using the SMT can be used as a non-invasive treatment to treat the frequency, duration, and intensity of the TTH, and to improve the quality of life.

Korean medicine treatment, including Nangan-jeon, of chronic constipation and abdominal pain in Lambert-Eaton myasthenic syndrome : A case report (Lambert-Eaton myasthenic syndrome 환자의 만성 변비 및 복통에 대한 난간전을 포함한 한방 치료 증례보고)

  • Han, Ji Hoon;Woo, Sang Ha;Park, Yu-kyeong;Choi, Seong-Hun;Lee, Yun-kyu;Lee, Jung Hee;Kim, Jae Soo;Lee, Hyun-Jong
    • Herbal Formula Science
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    • v.29 no.4
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    • pp.321-329
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    • 2021
  • This case study reports the effects of complex Korean medicine treatment, including Nangan-jeon, on Lambert-Eaton myasthenic syndrome (LEMS) accompanied by chronic constipation and abdominal pain as the main symptoms. A 39-year-old woman diagnosed with LEMS with major symptoms, including chronic constipation and acute abdominal pain, received Western treatment. The treatment efficacy was weak and symptoms recurred, so the patient received outpatient treatment and 13 days of hospitalization for active Korean medicine treatment, including Nangan-jeon. During outpatient treatment and hospitalization, defecation frequency and the numeric rating scale (NRS) for abdominal pain and abdominal cold feeling were measured. The NRS for abdominal pain and cold decreased from 8 at admission to 3 and 0, respectively, at discharge. Defecation frequency increased significantly from once or twice a month to once every 2-3 days during hospitalization. This study results that complex Korean medicine treatment, including Nangan-jeon may be useful for treating patients who mainly complain of autonomic neurological symptoms, among patients diagnosed with LEMS. In addition, it is believed that it could be basic data applicable to more LEMS patient treatment cases.

Seismic Capacity Evaluation of Existing Medium-and low-rise R/C Frame Retrofitted by H-section Steel Frame with Elastic Pad Based on Pseudo-dynamic testing (유사동적실험에 의한 탄성패드 접합 H형 철골프레임공법으로 보강 된 기존 중·저층 R/C 골조의 내진성능 평가)

  • Kim, Jin-Seon;Lee, Kang-Seok
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.25 no.4
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    • pp.83-91
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    • 2021
  • In this study, to improve the connection performance between the existing reinforced concrete (R/C) frame and the strengthening member, we proposed a new H-section steel frame with elastic pad (HSFEP) system for seismic rehabilitation of existing medium-to-low-rise reinforced concrete (R/C) buildings. This HSFEP strengthening system exhibits an excellent connection performance because an elastic pad is installed between the existing structure and reinforcing frame. The method shows a strength design approach implemented via retrofitting, to easily increase the ultimate lateral load capacity of R/C buildings lacking seismic data, which exhibit shear failure mechanism. Two full-size two-story R/C frame specimens were designed based on an existing R/C building in Korea lacking seismic data, and then strengthened using the HSFEP system; thus, one control specimen and one specimen strengthened with the HSFEP system were used. Pseudodynamic tests were conducted to verify the effects of seismic retrofitting, and the earthquake response behavior with use of the proposed method, in terms of the maximum response strength, response displacement, and degree of earthquake damage compared with the control R/C frame. Test results revealed that the proposed HSFEP strengthening method, internally applied to the R/C frame, effectively increased the lateral ultimate strength, resulting in reduced response displacement of R/C structures under large scale earthquake conditions.

A Study on the Changes in Specialization Degree and Cargo Volume by Cargo Type in Major Ports in Korea (우리나라 주요항만의 품목별 특화도와 물동량의 변동에 관한 연구)

  • Lee, Choong-bae;Su, Miao;Liu, Yanfeng
    • Journal of Korea Port Economic Association
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    • v.37 no.1
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    • pp.103-119
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    • 2021
  • Ports in Korea have been increasing in terms of volume while they have performed functions and roles such as industrial ports in promoting industries of their hinterlands as well as commercial ports supporting imports and exports. Nevertheless, specialization degree is different from port to port by cargo type and the changes in cargo volume. This study aims to analyze the structural changes and the degree of concentration and specialization by cargo type and port between 2001 and 2020. Top 10 ports were analyzed in terms of traffic volume by categorizing liquid, dry, general cargo and containers. HHI(Herfindahl-Hirschman Index), LQ(Location Coefficient), and shift-share analysis were employed in order to identify the degree of concentration, specialization and changes in cargo volume by port and cargo type. As a result of the analysis, the degree of port concentration and specialization for each cargo of 4 categories have maintained a high level, and no significant difference were found in fluctuations over the past 20 years. As a result of calculating the flucation of cargo volume through the shift-share analysis, the growth rate of liquid cargo was high in Yeosu Gwangyang Port, Pyeongtaek Dangjin Port in dry cargo, and Busan Port in general cargo and container ports. The result implies that it is not expected that the structural changes including degree of cargo concentration, specialization and relative fluctuation of cargo volume is significant in Korean ports in the future since the effects of economies of scale and clustering were achieved to the great degree.

Factor Prices and Markup in the Korean Manufacturing Industry: An Empirical Analysis 1975-2007 (한국의 생산요소가격 변화가 마크업의 변동에 미치는 영향에 관한 실증분석: 1975-2007)

  • Kang, Joo Hoon;Park, Sehoon
    • International Area Studies Review
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    • v.15 no.2
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    • pp.77-100
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    • 2011
  • The Korean economy have experienced the remarkable decreases in factor prices such as bond yields, real wage since the IMF foreign exchange crisis. This paper investigates the effects of the price changes in the factor markets on determining the level and cyclicality of industrial markups in the manufacturing industry. For this purpose, we construct a markup equation in the small open economy based on the production function including foreign intermediate goods and assuming constant returns to scale technology and AR(1) process of technological coefficient. Empirical results are summarized as the followings. The empirical results shows that the increased markups after the IMF crisis can be explained by the price decreases in the factor markets which result in lowering marginal costs. And we also observed counter cyclicality of markup, labor share and interest rates while real wages, technical coefficients, and production price index proved to be pro-cyclical. In conclusion, the price changes in factor market have contributed to the stickiness in markup fluctuation in the manufacturing industry.