• Proceedings of the PSK Conference
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• 2000.04a
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• pp.110.2-111
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• 2000

• The Journal of Internal Korean Medicine
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• v.12 no.1
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• pp.183-188
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• 1991

The following results were obtained according to these fact which is considered peviodically and bibliographically ; 1. The cause of bleeding of cough was Oegampunghan(外感風寒), Pyosaoesok(表邪外束), Chohwasangpye(燥火傷肺) in external cause, Eumhuhwadong(陰虛火動), Sinhu(腎虛), Hyulhu(血虛), Damhwajukyul(痰火積熱), Pyesuyul(肺受熱) ect. in internal cause. 2. The symptoms of bleeding of cough because of external cause was similar to generally cold symptom, because of internal cause were similar to Yeumhuhwadong(陰虛火動) and generanl Huyul(虛熱) symptom. 3. The treatment of external were Mahwangtang, Soshihotang, Sabaeksan ect. internal were Samultang, Yookmijihwangtang, Jaeumganghwatang, Gesosan ect.

• Herbal Formula Science
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• v.18 no.2
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• pp.53-76
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• 2010

This report describes 173 formulas related to which are mainly used Paeoniae Radix in Dongeuibogam. The following conclusions were induced through investigations on the formulas that are used Paeoniae Radix as a main component. 1. We found the formulas in Dongeuibogam that Paeoniae Radix is used as a main ingredient in each prescriptions. 22 times(12.4%) of them are recorded in women's disease chapter, 20 times(11.3%) are in feces chapter, 14 times(7.9%) are in uterus, 12 times(6.8%) are in wind chapter, 10 times(5.6%) are in fatigue chapter, 9 times(5.1%) are in blood chapter, which are arranged in order of frequency. 2. Formulas that utilize Paeoniae Radix as the main ingredient are used in the treatment of women's disease, diarrhea, paralysis, yin and yang-deficiency syndrome. They are also used for treating 117 different types of diseases. 3. The dosage of Paeoniae Radix in formulas is from 1 don(nearly 3.75g) to 1 nyang 5 don (nearly 56.25g), however 1 don has been taken the most for clinical application. 4. Paeoniae Radix can make various effects with other ingredient, like fulfilling yin and blood, relaxing muscles and allaying pain. And this can be found in the formulas such as Samultang(四物湯), Jakyackgamchotang(芍藥甘草湯), Sambaektang(三白湯).

• Journal of Haehwa Medicine
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• v.9 no.1
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• pp.305-317
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• 2000

To prove the effect of Sagunjatang(SGJT) and Samultang(SMT) extract on the wave of Human Body and Active Oxygen experimentally, QRS & Free Radical of extract and precipitate of SGJT and SMT was measured. The results were summarized as follows ; 1. SGJT extract and precipitate, as a result of measuring QRS and Free Radical, had a considerable effect on the function of immunity & pituitary gland. 2. BaekBokRung of SGJT, as a result of measuring QRS and Free Radical, had a considerable effect on the function of heart & spleen. 3. BaekChul and Gamcho of SGJT, as a result of measuring QRS and Free Radical, had a considerable effect on the function of stomach & duodenum. 4. YinSam of SGJT, as a result of measuring QRS and Free Radical, had a considerable effect on the function of immunity & spleen. 5. SMT extract and precipitate, as a result of measuring QRS and Free Radical, had a considerable effect on the function of immunity & uterus. 6. SukJiHwang of SMT, as a result of measuring QRS and Free Radical, had a considerable effect on the function of immunity & liver. 7. DangGui of SMT, as a result of measuring QRS and Free Radical, had a considerable effect on the function of heart & spleen. 8. ChunGung of SMT, as a result of measuring QRS and Free Radical, had a considerable effect on the function of spleen & pituitary gland. 9. BaekJakYak of SMT, as a result of measuring QRS and Free Radical, had a considerable effect on the function of stomach & duodenum. 10. SMT extract had an effect on the function of female Urogenital system, SGJT extract had an effect on the function of male Urogenital system. These results suggested that SGJT and SMT extract might be usefully applied for suppresing of Active Oxygen formation, preventing the aging, curing all the disease resulted from Active Oxygen.

• The Journal of Internal Korean Medicine
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• v.11 no.2
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• pp.104-111
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• 1990

The results of the Review of literature, the treatment of globus hystericus were summerized as follows ; first, use the method of adjusting the flow of vital energe, second, to break through the phlegm, to smooth the flow of vital energy, to releive stagnancy of vital energy, to keep air or gas going downward, and then, to restore the normal functioning of stagnancy of vital energy, to remove evil(heat) from the lung, antasthma to resolve phlegm, to regulate the vital function of the stomach as displling dampness through ditiresis by using mild-flavored drugs, to dispel pathogenic factors from the exterior of the body by diaphoresis. As the prescription of globus hystericus, Samultang were used the most frequently, and then, chilgitang, Gamisachiltang, Daechilgitang, Banhahubaktang, Gamileejintang, Bunsingiyum, samayum, Soyousan, Mokhyangbang were used.

• The Journal of Internal Korean Medicine
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• v.13 no.1
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• pp.117-123
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• 1992

This study has been carried out to investigate the treatment and drugs of Hu-Ro(虛勞) by referring to 35 literatures. The results were as follows; 1. The treatment of Hu-Ro(虛勞) is as follows. basic treatment : hujeokboji (虛卽補之) nojaonji sonjaonji (勞者溫之 損者溫之) general treatment : onbo (溫補) - bojungikgiseongyang (補中益氣升陽) chungbo (淸補) - jaeomganghwa (滋陰降火) 2. The drugs of Gi-Su(氣嗽) is as follows. gihu (氣虛) : bojungikgitang (補中益氣湯), sagunjatang (四君子湯) hulhu (血虛) : samultang (四物湯), daebojineum (大補眞飮) yanghu (陽虛) : oogwieum (右歸嗽), jwagihwna (左歸丸) eumhu (陰虛) : yukmihwan (六味丸), jwagihwna (左歸丸) eumyangguhu (陰陽俱虛) : gojineumja (固眞飮子), palmultang (八物湯)

• Journal of Korean Traditional Oncology
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• v.16 no.1
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• pp.55-61
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• 2011

Objectives : Epidermal growth factor receptor-inhibitors have demonstrated improved overall survival in patients with non-small cell lung cancer, but their use is associated with dermatologic adverse reactions that often require symptomatic treatment. Methods : A 44-year-old woman, who started the chemotherapy of Iressa$^{(R)}$ on August 2010, developed cutaneous symptoms such as papulopustular rash, dry skin, and pruritus on her face and scalp after taking Iressa$^{(R)}$ for four weeks. The patient visited our clinic with such symptoms on March 2011 and underwent herebal remedy targeted to alleviate the skin reactions. The severity of dermatologic symptoms was evaluated with the numeric rating scale and the Common Terminology Criteria for Adverse Events version 4.0. Results : Noticeable changes on the skin lesion were observed after the two months of treatment, without any dose modification of the Iressa$^{(R)}$. The cutaneous symptoms as papulopustular rash, dry skin and pruritus were improved and there was no adverse event induced by the treatment with herbal medicine. Conclusions : This case report suggests that the treatment with a herbal medicine, Samultang-gagambang be considered as a useful treatment to relieve EGFR-inhibitor induced dermatologic adverse reactions.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.1
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• pp.214-218
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• 2007

The water extracts of Samultang (Samul) has been used for treatment of ischemic heart and brain damage in Oriental traditional medicine. However, little is known about the mechanism by which the water extract of Samul rescues cells from oxidative damages in cisplatin-induced ototoxicity. Cisplatin is a widely used chemotherapeutic agent that is also highly ototoxic. This study was designed to investigate the protective effects of Samul on ciplatin-induced ototoxicity in HEI-OC1 auditory cells and organ of Corti explant culture. Cisplatin markedly decreased the viability of HEI-OC1 auditory cells. However, treatment of HEI-OC1 cells with Samul significantly reduced cisplatin-induced cell death and apoptotic characteristics through reduction of intracellular peroxide generation. Cisplatin induced cytotoxicity in isolated and cultured hair cell progenitors from postnatal rat cochleae. These progenitor cells are isolated from the lesser epithelial ridge (LER, or outer spiral sulcus cell) area of pre-plated neonatal rat cochlear segments. However, Samul completely protected the morphological changes of organ of Corti and LER. Taken together, these data suggest that the protective effects of the water extracts of Samul against cisplatin may be mediated by the reduction of intracellular peroxide generation.

• Journal of Pharmacopuncture
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• v.5 no.2
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• pp.92-108
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• 2002

According to the bibliographic studies of Depilation, the following conditions were made after literary studies.; 1. According to the period, The depilation have been named variously, for example, Balta(髮墮), Balgu(髮去), Balrak(髮落), Mobal(毛拔), Yupung(油風), Dokchang(禿瘡), Guijidu(鬼?頭), Dokban(禿班), etc. 2. The cause of depilation was deficiency of kidney(腎虛), defciency of Qi of the lung(肺氣虛), excessive heat of blood system(血熱), deficiency of Qi and blood system(氣血虛), deficiency of blood system(血虛), and endogenouse cause of, etc. 3. The depilation is meaning fallen hair in head. There are multiform type in the symptoms of depilation; round shape, ellipse type & bald head. 4. The herbal treatment was used Yukmijihwaghwan(六味地黃丸), Palmihwan(八味丸), Singihwan(腎氣丸), Hwangigunjungtang(黃耆建中湯), Samultang(四物湯), ect. and external herbal reatment was Sineungyangjindan(神應養鎭丹), Bangpungtongsungsan(防風通聖散), ect.

• Korean Journal of Oriental Medicine
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• v.5 no.1
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• pp.119-131
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• 1999

The effect of herbal medicine on 1-methyl-4-phenylpyridinium ion $(MPP^+)$ and 6-hydroxydopamine (6-OHDA) mediated neurotoxicity was studied in the rat phaeochromocytoma cell line PC12. The present study was designed to test the hypothesis that herbal medicine can protect cells from neurotoxiciy caused by $MPP^+$ and 6-OHDA. Exposure of PC12 cells to 0.2 mM $MPP^+$ and $50\;{\mu}M$ 6-OHDA for 24h resulted in a 50% cell death with respect to the control cells. $MPP^+$ induced cell death was reduced by Yollyounggobondan (延齡固本丹), Sagunjatang (四君子湯), Palmihwan (八味丸), and Palmultang (八物湯)(P<0.05). However, herbal medicines did not protect cells from degeneration caused by the 6-OHDA. Yollyounggobondan, Yungmijihwangwon (六味地黃元), Palmihwan, and Samultang (四物湯) were effective in protecting against $MPP^+$-induced ATP loss in PC12 cells (P<0.05). Yollyounggobondan and Palmultang were effect in neurite protection against 6-OHDA treatment in differentiated PC12 cells with NGF.