• 대한한의학회지
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• 제24권1호
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• pp.110-121
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• 2003

Objective : This research was performed to investigate the protective effect of Angelicae Dahuri Radix against ischemic damage using PC12 cells and global ischemia in gerbils. Methods : To observe the protective effect of Angelicae Dahuri Radix on ischemia damage, viability and changes in activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase and production of malondialdehyde (MDA) were observed after treating PC12 cells with Angelicae Dahuri Radix during ischemic insult. Gerbils were divided into three groups : a normal group, a 5-min two-vessel occlusion (2VO) group, and an Angelicae Dahuri Radix administered after 2VO group. The CCAs were occluded by microclip for 5 minutes. Angelicae Dahuri Radix was administered orally for 7 days after 2VO. The histological analysis was performed at 7 days after surgery. For histological analysis, the brain tissue was stained with 1% cresyl violet solution. Results : 1. Angelicae Dahuri Radix has a protective effect against ischemia in the CA1 area of the gerbil hippocampus 7 days after 5-minute occlusion, 2. In the hypoxia/reperfusion model using PC12 cells, Angelicae Dahuri Radix has a protective effect against ischemia in the dose of $0.2\mu\textrm{g}/ml$, $2\mu\textrm{g}/ml$ and $20\mu\textrm{g}/ml$, 3. Angelicae Dahuri Radix increased the activities of glutathione peroxidase and catalase. 4. The activity of superoxide dismutase (SOD) was increased by ischemic damage, which might represent self protection. This study suggests that Angelicae Dahuri Radix has some neuroprotective effect against neuronal damage following cerebral ischemia in vivo with a widely used experimental model of cerebral ischemia in Mongolian gerbils, and it also has protective effects on a hypoxia/reperfusion cell culture model using PC12 cells. Conclusions : Angelicae Dahuri Radix has protective effects against ischemic brain damage at the early stage of ischemia.

• 대한환경공학회지
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• 제30권12호
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• pp.1245-1254
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• 2008

지구온난화 영향의 사회적 비용(외부비용) 추산 방법을 제안하는 것이 이 연구의 목적이다. 지구온난화 영향의 피해를 받는 대상을 정의하기 위하여 엔드포인트 접근방법(endpoint approach)을, 피해를 받는 대상에 대한 경제적 가치를 산출하기 위하여 컨조인트 분석(conjoint analysis)을 각각 적용하였다. 보호대상에 대한 사회적 선호도와 지불의사금액(Willingness to Pay; WTP)을 측정하여 보호대상에 대한 경제적 가치를 추정한 결과 인간 건강은 62,261,700원/DALY(년)(장애보정생존연수), 사회 자산은 10,000원/10,000원이었다. 또한 각 보호대상에 대한 단위 피해를 정량화 한 피해계수(damage factor)와 인간 건강과 사회 자산에 대한 경제적 가치를 곱하여 GHG의 비용계수(cost factor)를 산출하였다. 온실가스 중 CO$_2$의 경우 비용계수는 13.52원/kg(13,520원/ton)으로 산출되었다. 제품 및 서비스로 인해 배출된 GHG 목록 결과값과 각 온실가스의 비용계수를 곱하여 지구온난화의 외부비용을 산출하였다.

• 대한기계학회논문집A
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• 제29권12권
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• pp.1586-1596
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• 2005

In this paper, a structural damage identification method (SDIM) is developed to identify the line crack-like directional damages generated within a cylindrical shell. First, the equations of motion for a damaged cylindrical shell are derived. Based on a theory of continuum damage mechanics, a small material volume containing a directional damage is represented by the effective orthotropic elastic stiffness, which is dependent of the size and the orientation of the damage with respect to the global coordinates. The present SDIM is then derived from the frequency response function (FRF) directly solved from the equations of motion of a damaged shell. In contrast with most existing SDIMs which require the modal parameters measured in both intact and damaged states, the present SDIM may require only the FRF-data measured at damaged state. By virtue of utilizing FRF-data, one may choose as many sets of excitation frequency and FRF measurement point as needed to acquire a sufficient number of equations for damage identification analysis. The numerically simulated damage identification tests are conducted to study the feasibility of the present SDIM.

• Smart Structures and Systems
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• 제19권4호
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• pp.393-402
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• 2017

Many vibration-based global damage detection methods attempt to extract modal parameters from vibration signals as the main structural features to detect damage. The local flexibility method is one promising method that requires only the first few fundamental modes to detect not only the location but also the extent of damage. Generally, the mode shapes in the lateral degree of freedom are extracted from lateral vibration signals and then used to detect damage for a beam structure. In this study, a new approach which employs the mode shapes in the rotary degree of freedom obtained from the macro-strain vibration signals to detect damage of a beam structure is proposed. In order to facilitate the application of mode shapes in the rotary degree of freedom for beam structures, the local flexibility method is modified and utilized. The proposed rotary approach is verified by numerical and experimental studies of simply supported beams. The results illustrate potential feasibility of the proposed new idea. Compared to the method that uses lateral measurements, the proposed rotary approach seems more robust to noise in the numerical cases considered. The sensor configuration could also be more flexible and customized for a beam structure. Primarily, the proposed approach seems more sensitive to damage when the damage is close to the supports of simply supported beams.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2007년도 정기 학술대회 논문집
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• pp.651-656
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• 2007

Changes in measured structural responses induced by a damage could be significantly smaller than those by environmental effects such as temperature and temperature gradients. It is highly desirable to develop a methodology to distinguish the changes due to the structural damage from those by the environmental variations. In this study, a novel method to extract the damage-induced deflection under temperature variations is presented using the outlier analysis on the deflections obtained using the modal flexibility matrices. The main idea is that temperature change in a bridge would produce global increase or decrease in deflections over the whole bridge while structural damages may cause local variations in deflections near the damage locations. Hence, the correlation between the deflection measurements may show high abnormality near the damage locations. A series of laboratory tests were carried out on a bridge model with a steel box-girder for 14 days. It has been found that the damage existence assessment and localization can carried out for a case with relatively small damage under the temperature variations

• 대한토목학회논문집
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• 제29권1A호
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• pp.61-73
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• 2009

본 논문에서는 강판형교의 주된 두 손상유형인 거더의 휨 강성 저하와 지점부의 손상을 검색하기 위해 가속도-임피던스 특성을 이용한 하이브리드 구조건전성 모니터링 기법을 제안하였다. 하이브리드 기법은 1) 전역적인 방법으로 손상의 발생을 경보하고, 2) 구조물의 구조 부재내의 발생된 손상을 분류하며, 3) 구조 부재에 따라 적절한 방법을 이용하여 세부적으로 분류된 손상을 평가하는 크게 3단계로 구성되었다. 첫 번째 단계에서는 가속도 특성 변화를 모니터링하여 전역적인 손상의 발생을 경보한다. 두 번째 단계에서는 임피던스 특성 변화를 모니터링하여 경보된 손상유형을 분류한다. 세 번째 단계에서는 모드변형에너지기반 손상지수법과 RMSD 기법을 이용하여 손상의 위치와 크기를 평가한다. 몇몇의 손상 시나리오에 의해 측정된 하이브리드 가속도-임피던스 신호를 이용한 모형 강판형교 실험을 통해 제안된 하이브리드 기법의 유용성을 평가하였다. 또한, 온도변화 및 지점손상 조건에 대한 실험을 통해 임피던스기반 손상모니터링의 정확도에 미치는 온도유발 영향을 검토하였다.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2006년도 정기 학술대회 논문집
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• pp.225-231
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• 2006

The purpose of this study is to develop a promising hybrid structural health monitoring system for structural joints. For this propose, the combined use of vibration-based techniques and electro-mechanical impedance technique is employed. For the verification of the proposed health monitoring scheme, a series of damage scenarios are designed to simulate various situations at which the connection joints can experience during their service life. The obtained experimental results, modal parameters and electro-magnetic impedance signatures, are carefully analyzed to recognize the connecting states and the target damage locations. From the analysis. it is shown that the proposed hybrid health monitoring system is successful for acquiring global and local damage information on the structural joints.

• Structural Engineering and Mechanics
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• 제67권3호
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• pp.245-254
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• 2018

In this paper, a Cloud Model based Fruit Fly Optimization Algorithm (CMFOA) is presented for structural damage identification, which is a global optimization algorithm inspired by the foraging behavior of fruit fly swarm. It is assumed that damage only leads to the decrease in elementary stiffness. The differences on time-domain structural acceleration data are used to construct the objective function, which transforms the damaged identification problem of a structure into an optimization problem. The effectiveness, efficiency and accuracy of the CMFOA are demonstrated by two different numerical simulation structures, including a simply supported beam and a cantilevered plate. Numerical results show that the CMFOA has a better capacity for structural damage identification than the basic Fruit Fly Optimization Algorithm (FOA) and the CMFOA is not sensitive to measurement noise.

• Smart Structures and Systems
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• 제15권5호
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• pp.1253-1270
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• 2015

In this paper Magnetic Charged System Search (MCSS) and Particle Swarm Optimization (PSO) are applied to the problem of damage detection using frequencies and mode shapes of the structures. The objective is to identify the location and extent of multi-damage in structures. Both natural frequencies and mode shapes are used to form the required objective function. To moderate the effect of noise on measured data, a penalty approach is applied. A variety of numerical examples including two beams and two trusses are considered. A comparison between the PSO and MCSS is conducted to show the efficiency of the MCSS in finding the global optimum. The results show that the present methodology can reliably identify damage scenarios using noisy measurements and incomplete data.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1999년도 가을 학술발표회 논문집
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• pp.249-256
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• 1999

This study is intended to propose a systematic procedure for the development of the reliability-based seismic safety and cost-effective Performance criteria for design and upgrading of long span PC bridges. In the paper, a set of cost function models for life cycle cost analysis of bridges is proposed. The total life cycle cost functions consist of initial cost and direct/indirect damage costs considering repair/replacement costs, human losses and property damage costs, road user costs, and indirect regional economic losses. The damage costs are successfully expressed in terms of Park-Ang median global damage indices and damage probabilities. The proposed approach is successfully applied to model bridges in both regions of a moderate seismicity area like Seoul, Korea and a high one like Tokyo, Japan. It may be expected that the proposed approach can be effectively utilized for the development of cost-effective performance criteria for design and upgrading of various types of bridges as well as long span PC bridges.