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Development of Individual Residue Analysis Method for Cyanazine in Agricultural Commodities as an Unregistered Herbicide in Korea (국내 미등록 제초제 cyanazine의 농산물 중 개별 잔류분석법 개발)

  • Choung, Myoung-Gun;Im, Moo-Hyeog
    • Journal of the Korean Society of International Agriculture
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    • v.30 no.4
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    • pp.339-346
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    • 2018
  • Cyanazine is a member of the triazine family of herbicides. Cyanazine is used as a pre- and post-emergence herbicide for the control of annual grasses and broadleaf weeds. This experiment was conducted to establish a determination method for cyanazine, as domestic unregistered pesticide, residue in major agricultural commodities using HPLC-DAD/MS. Cyanazine was extracted with acetone from representative samples of five raw products which comprised apple, green pepper, Kimchi cabbage, hulled rice and soybean. The extract was diluted with saline water and partitioned to dichloromethane for remove polar extractive in the aqueous phase. For the hulled rice and soybean samples, n-hexane/acetonitrile partition was additionally employed to remove non-polar lipids. The extract was finally purified by optimized florisil column chromatography. On a $C_{18}$ column in HPLC, cyanazine was successfully separated from co-extractives of sample, and sensitively quantitated by diode array detection at 220 nm. Accuracy and precision of the proposed method was validated by the recovery experiment on every major agricultural commodity samples fortified with cyanazine at 3 concentration levels per agricultural commodity in each triplication. Mean recoveries were ranged from 83.6 to 93.3% in five major representative agricultural commodities. The coefficients of variation were all less than 10%, irrespective of sample types and fortification levels. Limit of quantitation(LOQ) of cyanazine was 0.02 mg/kg as verified by the recovery experiment. A confirmatory method using LC/MS with selected-ion monitoring(SIM) technique was also provided to clearly identify the suspected residue.

Antioxidant and Anti-Inflammatory Activities of Ethanol Extract of Clematis trichotoma Nakai (할미밀망 에탄올 추출물의 항산화 및 항염증 활성 평가)

  • Jung, Jaemee;Shin, Mijoon;Jeong, Naeun;Hwang, Dahyun
    • Korean Journal of Clinical Laboratory Science
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    • v.53 no.2
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    • pp.165-173
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    • 2021
  • Clematis trichotoma Nakai (CTN) is a broad-leaved vine plant belonging to the family Ranunculus, native to Korea. Young leaves are used as food, and the stem and roots are used as medicinal materials. Antioxidant studies have been reported on the stems of CTN, but no studies have been conducted on the leaves. In this study, a 70% ethanol extract of CTN was prepared and its antioxidant and anti-inflammatory activities were investigated. For measuring the antioxidant activity, five assays (polyphenol and flavonoid content, reducing power, 2,2-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid), and 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity) were performed and CTN showed a concentration-dependent effect in all assays. To investigate the anti-inflammatory activity, we used RAW 264.7 cells. The concentrations (from 31.25 to 250 ㎍/mL) of CTN did not show cytotoxicity. CTN (250 ㎍/mL) inhibited dendritic transformation (34.4%) and also inhibited inflammation as seen by reduced levels of NO (77.4%), IL-6 (85.5%) and TNF-α (41.2%) compared to lipopolysaccharide (LPS). CTN (250 ㎍/mL) also suppressed the expression of the following genes: COX-2 (79.8%), iNOS2 (93.9%), IL-6 (87.6%), and TNF-α (77.3%) compared to LPS. These results demonstrated that CTN has excellent antioxidant and anti-inflammatory activities and can therefore be used as a natural biological resource.

Review of Fish Name on the Fishes of the Family Mugilidae in Korea and Resource Utilization (우리나라 숭어과 어류의 어명 및 자원 활용에 대한 고찰)

  • Ko, Eun Young;Park, Jong Oh;Lee, Kyoung Seon
    • Journal of Marine Life Science
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    • v.4 no.2
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    • pp.96-105
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    • 2019
  • The mugilidae fishes are common euryhaline species that live in coastal marine waters to freshwater areas. The taxonomy and nomenclature of the mugilidae fishes still remain unresolved because of their morphological similarities. Among the mugilidae fishes, most commonly consumed in Korea, are grey mullet (Mugil cephalus) and red lip mullet (Chelon haematocheilus). It is generally called 'mullet' without distinguishing between two mullets. Therefore, the aim of this study is to examine the scientific names and common names of mullet species used in Korea from the domestic journals and Korean old documents. The scientific name of grey mullet is M. cephalus, but that of redlip mullet is C. haematocheilus. But the genus of redlip mullet is still mixed with Chelon, Mugil, and Liza. The standard name of two mullet is not distinguished in the Korean dictionary, but they were clearly distinguished in the Japanese, English, and Chinese dictionaries. In the ancient Korean references, the mullet was called 'Chieo' or 'Sueo'. In most of the old literature, the distinction between grey mullet and redlip mullet is not clear. However, in Jasaneobo, it was written separately from grey mullet and redlip mullet, and attaching "ga" was different from now. The Korean standard name of redlip mullet is 'gasungeo', however, the fishermen in Jeollado and Gyoungsangdo call it 'chamsungeo'. Considering the negative perception of 'ga' character, it is proposed to change 'cham(眞)' instead of 'ga(假)' to improve economic value of red lip mullet.

Comparison of the bioactive compounds and anti-inflammatory effects found in different flower colors from Abeliophyllum distichum Nakai (미선나무 꽃 색에 따른 생리활성 화합물 및 항염증 활성 비교)

  • Jang, Tae-Won;Choi, Ji-Soo;Han, So-Yeon;Park, Hye-Jeong;Lee, Da-Yoon;Min, Young-Sil;Park, Jae-Ho
    • Journal of Applied Biological Chemistry
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    • v.65 no.3
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    • pp.203-213
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    • 2022
  • Abeliophyllum distichum (A. distichum, Korean endemic plant) is one genus and one species in the Oleaceae family. According to the color variation of petals and calyx, A. distichum is classified as A. distichum (white flower), A. distichum for. lilacinum (pink flowers), A. distichum for. eburneum (ivory flowers), and Okhwang 1 (golden flowers). In previous studies, bioactivities (antioxidant, anti-inflammatory, and anti-cancer) of A. distichum have been reported. We conducted a comparison of the differences in bioactive compounds and the anti-inflammatory effects on macrophages among four flowers of A. distichum (FAD). The identification and quantification of glycosides were analyzed by HPLC/PDA and LCMS. These results were shown FAD has rutin, hirsutrin, and acteoside. Antioxidant activity of FAD significantly decreased reactive oxygen species. In addition, FAD reduced the expression of pro-inflammatory mediators (nitric oxide, iNOS, and COX-2) in lipopolysaccharide-induced RAW 264.7 cells. For further study, we investigated the regulation of nuclear factor kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathways. In conclusion, FAD may exert anti-inflammatory effects by suppressing inflammatory mediators via regulations of NF-κB and MAPK signaling pathways. Therefore, these findings suggest that FAD is a potential resource as a preventative or therapeutic agent for inflammation.

Analysis of Eco-Citizenship Contents Elements in Home Economics Textbooks for the Introduction of Ecological Transformation Education (생태전환교육 도입을 위한 가정과 교과서의 생태시민성 내용 요소 분석)

  • Cho, Sung Mi;Park, Mi Jeong
    • Journal of Korean Home Economics Education Association
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    • v.35 no.2
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    • pp.1-20
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    • 2023
  • The purpose of this study is to extract and analyze ecological citizenship elements in the middle school home economics textbook used in the 2015 national curriculum for the introduction of ecological transformation education in the 2022 national curriculum. As a result of the analysis, the content analysis of the ecological citizenship factor was validated by six experts who are incumbent middle school home economics teachers, and the S-CVI value was 0.97, ensuring the validity of the ecological citizenship factor analysis. The results of analyzing 242 ecological citizenship factors extracted from home economics textbooks are as follows. According to the content area of the 2015 national home economics curriculum, the 'human development and family' area had the highest presence of ecological citizenship factors followed by the 'resource management and self-reliance' area and the 'home life and safety' area. Among the categories of ecological citizenship factors, 'value⋅attitude' was the most frequent, followed by 'process⋅function' and 'knowledge⋅understanding'. For each textbook composition system, ecological citizenship elements were extracted in the order of pictures, text, activities, and supplementary materials. There was a significant variation in the number of ecological citizenship factors among publishers, indicating the importance of the textbook writers' perception, interpretation, and direction of writing. Based on these analysis results, ecological citizenship teaching and learning activities applicable to home economics education were presented. This study highlights the potential for practicing ecological citizenship education in line with the new orientation of the curriculum on ecological transformation education through home economics education. Furthermore, it provides valuable baseline data for the development and implementation of textbooks for the 2022 national curriculum.

A Critical Perspective on the Integration of Service Delivery Systems in Child-Youth Policy (아동청소년정책 전달체계의 통합방안에 대한 비판적 고찰)

  • Chung, Ick-joong
    • Korean Journal of Social Welfare Studies
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    • v.40 no.1
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    • pp.297-322
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    • 2009
  • Child policy has focused on needy children with special emphasis on residual services but youth policy has implemented to promote capabilities of general adolescents by various activities. The fragmented implementation of child-youth policy by several ministries resulted in possible redundancy of target groups and insufficient service delivery system. Thus, the Ministry of Health, Welfare, and Family Affairs has pushed forward to integrate service delivery systems in child-youth policy after the former Ministry of Health and Welfare and the Government Youth Commission were integrated as part of a government reorganization plan. The purpose of this study is to review limitations of Lee Myung-bak government's plan to integrate child-youth policy and to make important suggestions for effective integration. Lee Myung-bak government's plan seeks to help children and adolescents prepare for the future and move forward with dreams and hope. However, this plan has fatal problems of overemphasizing the efficiency of finance without expansion of budget for children and adolescents. To achieve well-being tailored to one's life cycle, the full-scale expansion of budget is indispensible through the induction of the special fund or the special tax for children and adolescents. Fortunately, Lee Myung-bak government recognized child-youth policy as the social investment that would heighten national competitiveness in the long term, but there was insufficient child-youth policy infrastructure for new implementation. Therefore, Lee Myung-bak government needs a new design for integrated and universal child-youth policy that should take into account national human resource development plan and its economic development policy. The public responsibility for children and adolescents should be strengthened and, in addition, the network function in service delivery system should be complemented.

Comparative Study on the Storage Experiment of Cheorwon Onion (철원양파의 저장실험 연구)

  • Kim, D.H.;Kim, Y.B.;Koo, H.J.;Leeo, H.J.;Kang, C.S.;Baek, H.J.;Lee, J.S.;Chang, K.J.
    • Journal of Practical Agriculture & Fisheries Research
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    • v.21 no.2
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    • pp.27-33
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    • 2019
  • The purpose of this study was to compare the storage and post-storage changes of Cheorwon onions and onions for each region. Onion is a perennial plant belonging to the lily family. It is native to Persia of Southwest Asia. It is cultivated much in the temperate regions of the world. Cheorwon area is inland, but it has high continental climate due to its high altitude. Therefore it is said that the onion cultivated in this region has higher sugar content and higher taste than onion grown in southern region. Although the results of onion storage experiments in Cheorwon, Muan, Buan, and Changnyeong regions did not show much difference in weight, width, and height measurements before and after storage, Brix was reduced by approximately 1-2 brix. Before and after storing in each region, Brix was the highest in Cheorwon, Changnyeong, Buan, and Muan, and after saving, onions in Cheorwon were the same order. After each region was stored, the results showed that Cheorwon (112.3g), Muan (106g), Buan (102.1g) and Changnyeong (92.6g) had the highest hardness. Cold storage tests show that onions contain the least amount of corruption in paper boxes, while Cheorwon onions have the lowest level of corruption in other areas.

Evolution of Healthcare Service Disparities: A Case Study of Primary Care Services in Korea, 1995-2021 (보건의료 서비스의 공간적 불균등 분포 변이에 대한 연구: 1995년부터 2021년까지 초기진료기관을 대상으로)

  • Hyun Kim;Yena Song
    • Journal of the Economic Geographical Society of Korea
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    • v.26 no.3
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    • pp.289-309
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    • 2023
  • While South Korea's universal healthcare system has garnered attention in public health, the issue of inequality in healthcare service provision among different age groups has incessantly become a significant concern. The focus of this concern is primarily on essential healthcare services, encompassing fundamental aspects of healthcare such as internal medicine, family medicine, and pediatric and adolescent care. This inequality is not limited to differences among age groups (both junior and senior demographics) but also extends to potential disparities in healthcare services based on geographic location, particularly in urban and rural contexts. This paper aims to investigate disparities in primary healthcare service resources in South Korea's evolving economic landscape between 1995 and 2021. We utilize a set of inequality indices with a spatial perspective through geographic cluster analysis. The findings reveal that concerns about inequality have been amplified during various economic events, including the IMF crisis in 1999, the global financial crisis in 2008, and the COVID-19 pandemic in 2020. These years are identified as significant phases that have contributed to manifesting spatial disparities in primary healthcare provisions, with a particular emphasis on the senior-aged population rather than junior or all population groups. Our findings underscore the pressing need to address the unequal distribution of essential healthcare resources as part of preparedness for potential economic impacts, requiring a comprehensive consideration of the interconnected nature of demographic and spatial dimensions in healthcare services.

Study on Establishment of Space Operation Plan for Yangpyeong-gun Public Library (양평군 공공도서관 공간 운영 계획 수립에 관한 연구)

  • Inho Chang;Younghee Noh;Woojung Kwak
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.35 no.1
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    • pp.301-324
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    • 2024
  • In this study, we attempted to propose operational directions for each space in order to transform the newly built library in Yangpyeong-gun into a space for cultural enjoyment and creativity development for local residents. To this end, the purpose is to understand the space composition status of Yangpyeong-gun public libraries and establish an operation plan (draft) for the space to be constructed. To this end, we analyzed the names, operation status, and cases of similar spaces in other libraries, and analyzed the spatial characteristics of library cases to establish a space operation plan for the Yangpyeong-gun public library. As a result of the study, it is important to utilize spaces such as children's resource rooms to improve early reading habits for infants and children, contribute to development, and develop various senses, and small theaters should be planned with a focus on large-scale performances. Furniture and space for reading and relaxation should be provided next to Byeokmyeonga & Bookstair, and it should be operated as a communication space where small talk is possible within a certain limit. It is necessary to operate the multipurpose room by activating experiential creative activities and creative performances. It is necessary for the club room to establish an operation plan through regular communication and opinion sharing. The maker space space is a space that supports various creative activities, and the general data room is a place that provides materials on all topics and must be operated by regularly communicating with users and reflecting their opinions. Lastly, I would like to suggest that the family room should be used like a book cafe where children and parents can freely drink tea together in the same space.

A Study of Leadership Competencies and Job Embeddedness among Child Group Home Workers : The Double Mediating Effects of Social Capital and Organizational Culture (아동 공동생활가정 종사자의 리더십 역량과 직무착근도 연구: 사회적자본과 조직문화의 이중 매개효과)

  • Goo, Hyeongyu;Kim, Bongwha
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.3
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    • pp.593-604
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    • 2024
  • This study examined the effect of leadership competence on job embeddedness among child co-residence workers to mitigate the negative impact of human resource management on their low job tenure and treatment. The study initially tested the mediating effects of social capital and organizational culture between the two variables, thereby suggesting ways to enhance job attendance among workers in children's shared family homes. The results of the study are as follows. Leadership competencies among child co-residence workers were found to have a positive effect not only on job embeddedness but also on social capital and organizational culture. Social capital and organizational culture were identified as mediators in the relationship between leadership competencies and job commitment The primary significance of this study lies in its identification of the relationship between leadership competence and job attendance - a factor previously overlooked. This finding offers a pathway to increase job attendance. Furthermore, the study expands the scope of relevant variables to include leadership competence, social capital, and organizational culture. Finally, it sheds light on the mediating effects of social capital and organizational culture on the relationship between leadership competence and job embeddedness.