• Molecules and Cells
• /
• 제38권5호
• /
• pp.390-395
• /
• 2015

Degradation of chlorophyll (Chl) by Chl catabolic enzymes (CCEs) causes the loss of green color that typically occurs during senescence of leaves. In addition to CCEs, STAYGREEN1 (SGR1) functions as a key regulator of Chl degradation. Although sgr1 mutants in many plant species exhibit a staygreen phenotype, the biochemical function of the SGR1 protein remains elusive. Many recent studies have examined the physiological and molecular roles of SGR1 and its homologs (SGR2 and SGR-LIKE) in Chl metabolism, finding that these proteins have different roles in different species. In this review, we summarize the recent studies on SGR and discuss the most likely functions of SGR homologs.

• 한국응용약물학회:학술대회논문집
• /
• 한국응용약물학회 1993년도 제2회 신약개발 연구발표회 초록집
• /
• pp.72-72
• /
• 1993

Chan'su the dried toad venom preparation, has been used for centuries as a cardiotonic a local anesthetic and in the treatment of ecphyma. Bufadienol ides are major effective components of Chan'so. Their pharmacological activities have been studies to date. However, their pharmacokinetic and metabolism have not been studied. Considering variously divergent pharmacological actions of bufadienolides we decided to examine their metabolism and their other biological activites. We isolated and purified various components of bufadienolides. Cinobufagin and bufalin are prominent components. Firstly we examined metabolism of cinobufagin and found that this compound was extensively metabolized into various metabolites by mixed-function oxidase and deacetylase.

• Journal of Microbiology
• /
• 제45권1호
• /
• pp.75-78
• /
• 2007

Nucleotide and amino acid substitution pattern in vif gene of the Korean clade of HIV-1 isolated from Koreans were analyzed using consensus sequences. At nucleotide level, transition/transversion substitution ratio was 1.88, and nonsynonymous/synonymous substitution ratio was 2.67, suggesting a divergent evolution in the Korean clade. At amino acid level, there were 17 substitutions and $G{\rightarrow}E$ substitution at position 37 may be responsible for change in predicted secondary structure.

• 공학교육연구
• /
• 제23권2호
• /
• pp.3-13
• /
• 2020

Key objective of cornerstone design is that students are able to experience developing creative design concepts through team activities, but the objective is hard to achieve. Based on a study of research materials, this paper asserts that the possibilities of creative problem solving can be promoted in question-centering ideation model if design artifacts are represented in some forms that could invoke design thinking and then the solution space is appropriately established. In particular, design problem on which divergent questions are asked should be explored and defined so that it can be a linguistic artifact represented by various visual aids. It is recommended that curriculum is modified so that students can experience creative conceptual design.

• 한국항공운항학회지
• /
• 제22권3호
• /
• pp.33-49
• /
• 2014

The object of this study is to verify the effects of job stress on burnout and job satisfaction of flight attendants and to confirm the difference in the effect on the consciousness of full service carrier and low cost carriers' flight attendants. In order to confirm, the study examines the relationship between job stress, burnout, and job satisfaction of airline cabin attendant. A survey was done for 55days from January 5th 2014 on flight attendants and total 200 valid samples were analysed. The results of the study demonstrated significant relationship and difference in job stress, burnout and job satisfaction of flight attendants between full service carrier and low cost carrier. As a result, the study is significant as it satisfaction between divergent airline work environment.

• 한국수학교육학회지시리즈A:수학교육
• /
• 제45권2호
• /
• pp.155-163
• /
• 2006

In this paper, we focus on the analysis of the results of CAS-K (Creative Attitude Scale-Korea) including 33 items of 7 factors. Using the analysis gives us the information about students' creative attitude for each factor. We introduce three methods of the analysis about the results of CAS-K; total scores analysis, mean value of each factor analysis, and CAS-K map analysis. We develop the CAS-K map based on the mean value of each factor and three categories of factors. These categories are divergent attitude (fluency, appropriateness), problem solving attitude (positiveness, independency, concentration), and convergent attitude (convergency, accuracy). This analysis of the results of CAS-K can be a source of creative attitude to foster mathematical creativity.

• 대한가정학회지
• /
• 제39권12호
• /
• pp.205-224
• /
• 2001

This article presents the development of a self-report measure of Korean Marital Satisfaction Scale. Based on 'Family Process Model'and interviews with 183 married couple, 3 domain structures with 74 items were identified, which included interactional process, emotional process, and intellectual process. It was administerd to 289 couples to test reliability and validity. Overall reliability coefficients were high for each of the individual domains($\alpha$=.62 to $\alpha$=.93). Face validity, content validity, content validity and concurrent validity respectively were demonstrated good. Additionally, divergent validity with scales of self-esteem and depression was observed. These results support the reliability and psychometric validity of the Korean Marital Satisfaction Scale in the assessment of key dimensions of marital process of Korean couples.

• 대한치과의사협회지
• /
• 제21권10호통권173호
• /
• pp.829-833
• /
• 1983

The author surveyed on the maxillary median diastema of 1,686(male; 850, female; 836) 'H' and 'K' primary school children aged from 6 to 13. The results were as follows : 1. The prevalence of the maxillay median diastema was 12.6% in male, 7.9% in female and 10.3% in both sexes. 2. The prevalence of the maxillary median diastema showed the highest rate in 9 years old boys and 8 years old girls, and it showed decreasing tendency according to increasing age. 3. The prevalence of mesiodens was 0.6% and boys had higher rate than girls. 4. Mean value of 'Frenum Distance' was 5.8mm in male, 5.7mm in female and mean value of 'Divergent Degree' was 2.0mm in male, 1.6mm in female.

• Mycobiology
• /
• 제41권1호
• /
• pp.1-12
• /
• 2013

Msi1-like (MSIL) proteins, which are eukaryote-specific and contain a series of WD40 repeats, have pleiotropic roles in chromatin assembly, DNA damage repair, and regulation of nutrient/stress-sensing signaling pathways. In the fungal kingdom, the functions of MSIL proteins have been studied most intensively in the budding yeast model Saccharomyces cerevisiae, an ascomycete. Yet their functions are largely unknown in other fungi. Recently, an MSIL protein, Msl1, was discovered and functionally characterized in the pathogenic yeast Cryptococcus neoformans, a basidiomycete. Interestingly, MSIL proteins appear to have redundant and unique roles in both fungi, suggesting that MSIL proteins may have evolutionarily divergent roles in different parts of the fungal kingdom. In this review, we will describe the current findings regarding the role of MSIL proteins in fungi and discuss future directions for research on this topic.

• Mycobiology
• /
• 제39권4호
• /
• pp.249-256
• /
• 2011

Microorganisms are significantly affected when the ambient pH of their environment changes. They must therefore be able to sense and respond to these changes in order to survive. Previous investigators have studied various fungal species to define conserved pH-responsive signaling pathways. One of these pathways, known as the Pal/Rim pathway, is activated in response to alkaline pH signals, ultimately targeting the PacC/Rim101 transcription factor. Although the central signaling components are conserved among divergent filamentous and yeast-like fungi, there is some degree of signaling specificity between fungal species. This specificity exists primarily in the downstream transcriptional targets of this pathway, likely allowing differential adaptation to species-specific environmental niches. In this review, the role of the Pal/Rim pathway in fungal pH response is discussed. Also highlighted are functional differences present in this pathway among human fungal pathogens, differences that allow these specialized microorganisms to survive in the various micro-environments of the infected human host.