• Title/Summary/Keyword: controlled synthesis

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Regulation of Blood Glucose Homeostasis during Prolonged Exercise

  • Suh, Sang-Hoon;Paik, Il-Young;Jacobs, Kevin A.
    • Molecules and Cells
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    • v.23 no.3
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    • pp.272-279
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    • 2007
  • The maintenance of normal blood glucose levels at rest and during exercise is critical. The maintenance of blood glucose homeostasis depends on the coordination and integration of several physiological systems, including the sympathetic nervous system and the endocrine system. During prolonged exercise increased demand for glucose by contracting muscle causes to increase glucose uptake to working skeletal muscle. Increase in glucose uptake by working skeletal muscle during prolonged exercise is due to an increase in the translocation of insulin and contraction sensitive glucose transporter-4 (GLUT4) proteins to the plasma membrane. However, normal blood glucose level can be maintained by the augmentation of glucose production and release through the stimulation of liver glycogen breakdown, and the stimulation of the synthesis of glucose from other substances, and by the mobilization of other fuels that may serve as alternatives. Both feedback and feedforward mechanisms allow glycemia to be controlled during exercise. This review focuses on factors that control blood glucose homeostasis during prolonged exercise.

Ultrathin graphene-like 2D porous carbon nanosheets and its excellent capacitance retention for supercapacitor

  • Gopalakrishnan, Arthi;Badhulika, Sushmee
    • Journal of Industrial and Engineering Chemistry
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    • v.68
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    • pp.257-266
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    • 2018
  • Here, a controlled green synthesis route involving hydrothermal pre-carbonization cum pyrolysis is reported that converts cucumber into graphene-like carbon nanosheets for supercapacitor application. Transmission electron microscopy analysis reveals the formation of ultra-thin carbon nanosheets with distributed pores. This cucumber derived carbon exhibits high specific capacitance of $143F\;g^{-1}$ in aqueous electrolyte. The two-electrode symmetric cell exhibits a specific capacitance of $58F\;g^{-1}$ at high current density, and high capacitance retention of 97% after 1000 cycles. This simple low-cost process involving widely available cucumber as biomass precursor is a promising, commercially viable approach for developing high-performance supercapacitors.

Synthesis of Amphiphilic Poly(alkyl methacrylate-b-methacrylic acid) by Group Transfer Polymerization and Selective Hydrolysis

  • Soon Ki Kwon;Weon Jung Choi;Yun Hi Kim;Sam Kwon Choi
    • Bulletin of the Korean Chemical Society
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    • v.13 no.5
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    • pp.479-482
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    • 1992
  • Several poly(alkyl methacrylate-b-t-butyl methacrylate) diblock copolymers were synthesized by group transfer polymerization. The molecular weight of poly(t-butyl methacrylate) segments and the composition of the resulting block copolymers were controlled by the monomer feed ratios and mole ratios of monomer to initiator. The poly(t-butyl methacrylate) block was quantitatively hydrolyzed to poly(methacrylic acid) block by refluxing with a catalytic amount of p-toluenesulfonic acid in dioxane at $100^{\circ}C$ for 12 hrs. The thermogravimetric analysis of poly(alkyl methacrylate-b-t-butyl methacrylate) exhibited the lose of isobutylene and subsequent anhydride formation in the range of $205-300^{\circ}C$.

Synthesis of Size-Controlled Urchin Ag Nanoparticles and Surfcace Enhanced Raman Spectroscopy (SERS) (크기가 조절된 성게 모양의 실버나노 입자의 합성과 표면 라만 증강)

  • Lee, Young Wook;Shin, Tae Ho
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.32 no.6
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    • pp.454-457
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    • 2019
  • Controlling the shape of Ag nanoparticles (NPs) is very difficult. In the present work, urchin Ag NPs with different sizes and pod length control have been synthesized successfully in high yield by the concentration of a reducing agent. Unique Ag NPs were observed by TEM and SEM. These nanocrystals exhibit tunable surface plasmon resonance properties from the visible to near-infrared regions. They were applied to surface-enhanced Raman scattering (SERS) substrates using rhodamine 6G (R6G), benzenethiol (BT), and 4-amino benznethiol (4-ABT) molecules. The enhanced local field effect due to the sharp pod length, size, and surface plasmon of the urchin Ag NPs resulted in enhanced SERS properties and can serve as high-sensitivity substrates for SERS measurements.

Synthesis of Size Controlled Gold Nanoparticles and Surface Enhanced Raman Spectroscopy (SERS) Effect (크기가 조절된 골드 나노 입자의 합성과 표면 라만 증강의 효과)

  • Lee, Young Wook;Shin, Tae Ho
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.32 no.6
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    • pp.462-465
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    • 2019
  • Nanoscale gold particles have been intensively researched due to their potential applications in catalysis, electronics, plasmonics, and biological assays. In our study, we fabricated gold nanoparticles (NPs) that were synthesized in an aqueous environment via the reduction of $HAuCl_4$ by ascorbic acid (AC) with a sodium citrate (SC) surfactant. Highly monodispersed gold particles with sizes ranging from 123 to 184 nm were prepared in high-yield by a surfactant concentration. The structural and optical properties of the synthesized gold nanoparticles were characterized by transmission electron microscopy (TEM) and UV-vis spectroscopy. The prepared nanoparticles exhibited efficient surface-enhanced Raman scattering (SERS) properties that were dependent on their on size.

In Situ Microfluidic Synthesis of Monodisperse PEG Microspheres

  • Choi, Chang-Hyung;Jung, Jae-Hoon;Hwang, Taek-Sung;Lee, Chang-Soo
    • Macromolecular Research
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    • v.17 no.3
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    • pp.163-167
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    • 2009
  • This study presents a microfluidic method for the production of monodisperse poly(ethylene glycol) (PEG) microspheres using continuous droplet formation and in situ photopolymerization in microfluidic devices. We investigated the flow patterns for the stable formation of droplets using capillary number and the flow rate of the hexade-cane phase. Under the stable region, the resulting microspheres showed narrow size distribution having a coefficient of variation (CV) of below 1.8%. The size of microspheres ($45{\sim}95{\mu}m$) could be easily controlled by changing the interfacial tension between the two immiscible phases and the flow rates of the dispersed or continuous phase.

Technology Trends for Motion Synthesis and Control of 3D Character

  • Choi, Jong-In
    • Journal of the Korea Society of Computer and Information
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    • v.24 no.4
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    • pp.19-26
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    • 2019
  • In this study, we study the development and control of motion of 3D character animation and discuss the development direction of technology. Character animation has been developed as a data-based method and a physics-based method. The animation generation technique based on the keyframe method has been made possible by the development of the hardware technology, and the motion capture device has been used. Various techniques for effectively editing the motion data have appeared. At the same time, animation techniques based on physics have emerged, which realistically generate the motion of the character by physically optimized numerical computation. Recently, animation techniques using machine learning have shown new possibilities for creating characters that can be controlled by the user in real time and are expected to be developed in the future.

Gallium nitride nanoparticle synthesis using nonthermal plasma with gallium vapor

  • You, K.H.;Kim, J.H.;You, S.J.;Lee, H.C.;Ruh, H.;Seong, D.J.
    • Current Applied Physics
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    • v.18 no.12
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    • pp.1553-1557
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    • 2018
  • Gallium nitride (GaN) nanoparticles are synthesized by the gallium particle trapping effect in a $N_2$ nonthermal plasma with metallic Ga vapor. A proposed method has an advantage of synthesized GaN nanoparticle purity because the gallium vapor from the inductively heated tungsten boat does not contain any impurity source. The synthesized particle size can be controlled by the amount of Ga vapor, which is adjusted using the plasma emission ratio of nitrogen to gallium, owing to the particle trapping effect. The synthesized nanoparticles are investigated by electron microscopy studies. High-resolution transmission electron microscopy (HRTEM) studies confirm that the synthesized GaN nanoparticles (10-40 nm) crystallize in a single-phase wurtzite structure. Room-temperature photoluminescence (PL) measurements indicate the band-edge emission of GaN at around 378 nm without yellow emission, which implies that the synthesized GaN nanoparticles have high crystallinity.

Synthesis and COX-2 Inhibitory Activities of Rutaecarpine Homologues

  • Jung, He-Jin;Kim, Seung-Il;Chang, Hyeun-Wook;Jahng, Yurng-Dong
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.250.2-250.2
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    • 2003
  • A series of rutaecarpine homologues were prepared from 2,3-polymethylene-4(3H-quinazolinones in 4 steps [i) PhCHO/Ac$_2$O, ⅱ) O,$_3$ ⅲ) PhNHNH$_2$HCl, and ⅳ) PPA], in which dihedral angles of the two planar aromatic rings (indole and 4(3H)-quinazolinone) were controlled in a regular fashion. Their inhibitory activities on COX-1 and COX-2 were evaluated to show that the inhibitory activities were increased with the increase of the length of methylene unit while selectivities on COX-2 decreased leading a loss in trimethylene bridged system.

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An Asymmetric Synthesis of (+)-Polyoxamic acid

  • Lee, Ki-Han;Oh, Chang-Young;Lee, Kee-Young;Kim, Yong-Hyun;Lee, Yiu-Suk;Joo, Jae-Eun;Ham, Won-Hun
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.362.3-362.3
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    • 2002
  • The Polyoxin complex is an antifungal antibiotics produced by Streptomyces cacaoi var. asoensis that exhibit marked and selective activity against pytopathogenic fungi. They incorporate carbamoylated dipeptides attached to the sugar moiety. Controlled alkaline hydrolysis of polyoxins result in several products. one of which has been identified as (+)-(2S. 3S, 4S)-2-amino-3. 4. 5-trihydroxypentonic acid(polyoxamic acid). A variety of chemical syntheses of polyoxamic acid have been developed over several years. (omitted)

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