• 대한신경과학회지
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• 제36권4호
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• pp.345-349
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• 2018

Familial Creutzfeldt-Jakob Disease (fCJD) is characteristic with older age onset, relatively low occurrence rate, slower progression and lower possibility of developing myoclonus, cerebellar, pyramidal signs and visual disturbance compared with classical sporadic CJD. We report a case of 75-year-old male patient presented with sudden onset of right side weakness with Broca's aphasia who has been diagnosed with fCJD with V180I mutation. This case indicates that fCJD with V180I mutation can have stroke-like initial presentation.

• 인지과학
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• 제23권4호
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• pp.425-455
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• 2012

다차원 구어 단기기억 기제는 크게 음운적 통로와 어휘-의미적 통로로 구분된다. 전자를 음운단기기억, 후자를 의미단기기억이라고 할 수 있는데, 단기기억 과제를 정상적으로 수행하기 위해서는 두 통로 모두의 정보를 활발히 활용하여야 한다. 그리고 음운단기기억은 다시 음운입력완충기와 음운출력완충기로 나누어지며, 음운입력완충기는 음운자극의 입력 시, 음운출력완충기는 음운 산출 시에 작동한다. 본 연구에서는 유사한 수준의 전도 실어증 증상을 보이는 세 명의 환자에 대해, 각각의 언어 수행력을 구어 단기기억의 다차원적 측면에서 분석하였다. 그러기 위하여 세 명의 전도 실어증 환자들에게 단어 수준과 문장 수준에서 스스로 말하기, 따라말하기, 스스로 쓰기, 받아쓰기의 네 가지 양태의 언어과제를 실시하여 수행력을 비교 분석하였고, 숫자폭검사와 언어학습검사를 이용하여 음운단기기억력과 의미단기기억력을 평가하였다. 그 결과 세 대상자들은 네 양태의 언어 검사에서 다양한 수행력과 오반응 유형을 보였고, 단기기억력 검사 결과도 동일하게 나타나지 않았다. 즉 전도 실어증 환자들의 언어 수행력은 의미단기기억 또는 음운단기기억의 결함으로 설명될 수 있으며, 음운단기기억 가운데에서도 음운입력완충기, 음운출력완충기 혹은 둘 다의 결함 여부에 따라 언어특성이 상이하게 나타날 가능성을 제시하고 있다. 본 연구에서는 전도 실어증 환자들의 언어 검사와 단기기억력 검사 결과를 바탕으로, 언어와 다차원 구어 단기기억력과의 관계에 대하여 논의하고 있다.

• 말소리와 음성과학
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• 제4권3호
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• pp.137-142
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• 2012

The aim of this study is to investigate the usefulness of the multiple-choice name matching test (MC-NMT) in adults with aphasia by comparing the Korean version of the Boston Naming Test (K-BNT) and subsets of the Korean version of the Western Aphasia Battery (K-WAB). Thirty-nine patients who suffer from aphasia participated in the study. All patients were examined by the K-BNT, MC-NMT and K-WAB. The MC-NMT consisted of the 30 original BNT object stimuli which were presented with four response choices (written words) with similar frequency, including one correct and three incorrect responses. Cards containing the drawings were presented to the patient one at time. An item was passed if the patient chose the correct response within 10 seconds. We subdivided two groups into a total group and a low K-BNT group (at and below 15 points). We evaluated the correlation between the K-BNT, MC-NMT score and production, naming, repetition, comprehension, reading and writing scores in subsets of the K-WAB. There was a highly positive correlation between the K-BNT score and naming score of the K-WAB in total patients. However, the MC-NMT was highly correlated with reading scores in the K-WAB. In low score K-BNT patients, the K-BNT strongly correlated with production, naming and repetition scores of the K-WAB. These findings mean that K-BNT reflects motor language function. However, the MC-NMT was strong correlated comprehension, reading and writing of the K-WAB. This finding reflects sensory language function. We suggest that the combination of K-BNT and newly developed MC-NMT will be useful to evaluate speech functions in aphasic patients.

• 동의신경정신과학회지
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• 제16권2호
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• pp.251-257
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• 2005

본 증례의 뇌경색 초피질감각실어증 환자는 한양방 치료 및 언어치료 시행을 통하여 K-WAB, K-BNT 등 표준화된 실어증 검사의 수행능력의 향상을 보였으며, 이야기 배열 과제에 대한 발화 분석에서 주제진술률의 향상, 의미착어와 음소착어의 감소 등 실제적 담화능력의 향상을 나타내었다. 실어증 환자의 경과관찰에서 이야기배열그림이 활용이 유용하리라 사료된다. 이후, 한방치료의 효과를 검증 및 이야기 배열과제 발화분석의 유용성에 대한 확대된 연구가 필요하다.

• 음성과학
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• 제12권2호
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• pp.101-108
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• 2005

Apraxia of phonation (AOP) has often been described as a feature of apraxia of speech or of severe non-fluent type of aphasia. Pure AOP is rare and, to our knowledge, only two cases have been reported. Brain lesion sites of the reported cases were not those sites known to be responsible for apraxia of speech. This study presents a case of AOP which resulted from the secondary stroke in the left corona radiata immediately following the first stroke in the left temporoparietal lobe. A 61-year old right-handed man shwoed a global type of aphasia after the first cerebral infarction, but was able to generate spontaneously some short fragments of speech. On the day after the first infarction, he suffered from the secondary infarction, leaving him a complete loss of voluntary phonation. He did not showed any significant change in language functions. Several occurrences of involuntary phonation were observed upon laughing or crying. He was also able to cough unintentionally. A vidoe-stroboscopic examination failed to reveal any evidence of structural and functional impairment in larynx. Although this case is not of pure form of AOP, AOP appeared after the secondary stroke without significant changes of language impairment since the first stroke. Therefore, AOP may be a consequence of the brain lesion from the secondary stroke even though we cannot rule out the possibility of an additive effect of the secondary to the first stroke.

• 말소리와 음성과학
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• 제5권3호
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• pp.103-111
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• 2013

Traditionally it has been assumed that written abilities are completely dependent on phonology. Therefore spoken and written language skills in aphasic patients have been known to exhibit similar types of impairment. However, a number of latest studies have reported the findings that support the orthographic autonomy hypothesis. The purpose of this study was to examine whether fluent aphasic patients have discrepancy between speaking and writing skills, thereby identifying whether the two skills are realized through independent processes. To this end, this study compared the K-FAST speaking and writing tasks of 30 aphasia patients. In addition, 16 aphasia patients, who were capable of producing sentences not only in speaking but also in writing, were compared in their performances at each phase of the sentence production process. As a result, the subjects exhibited different performances between speaking and writing, along with statistically significant differences between the two language skills at positional and phonological encoding phases of the sentence production process. Therefore, the study's results suggest that written language is more likely to be produced via independent routes without the mediation of the process of spoken language production, beginning from a certain phase of the sentence production process.

• Journal of Korean Neurosurgical Society
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• 제48권6호
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• pp.524-527
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• 2010

Temporary disruption of the blood-brain barrier (BBB) after cerebral angiography is presumably caused by nonionic radiographic contrast medium (CM). We hereby report a case of 58-year-old woman who developed decreased mentality, global aphasia and aggravated right hemiparesis after cerebral angiography. Brain CT examination demonstrated gyriform enhancement throughout the left cerebral cortex and thalamus. MR diffusion did not reveal acute infarction. MR angiography did not show any stenosis, spasm or occlusion at the major cerebral vessels. Follow-up CT scan after 1 day did not show any gyriform enhancement. Worsened neurologic signs and symptoms were improved completely after 7 days. In the present study, disruption of the BBB with contrast medium after angiography seems to be the causative factor of transient neurologic deterioration.

• 대한한방내과학회지
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• 제25권4호
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• pp.167-176
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• 2004

Objectives : This study was designed to report the clinical effects of scalp acupuncture on patients who suffered from broca aphasia caused by cerebral hemorrhage, Methods : Scalp acupuncture therapy was applied on the above patients for several weeks, For the evaluation of improvement, language field was monitored by aphasia test(RISS) and speech field was monitored by phonetic analysis in the computerized speech lab. Results : According to the above evaluation items, the treatment was beneficial. The score of most items rose in the language field. And scalp acupuncture affected VOT, TD and articular error patterns positively in the speech field. Conclusions : The above results suggest that scalp acupuncture has good effects on the patients with broca aphasia caused by cerebral hemorrhage.

• 재활치료과학
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• 제8권2호
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• pp.79-88
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• 2019

목적 : 경험학습모델에 따라 하나의 체계적 프로그램으로 결합하였는데 이 접근법의 목표는 환자와 보호자들의 이해를 돕고 필요한 것을 인지시키는 것에 초점을 두었다. 이러한 선행연구들의 결과를 근거로 본 연구자는 환자와 대화상대자 사이의 의사소통 개선을 위한 보호자 교육과 경험학습모델에 근거한 그룹훈련의 장점을 알아보고자 하였다. 연구방법 : 이 연구에서는 부산광역시 소재에 있는 종합병원에 입원한 40~50세의 비유창성 실어증 환자 6명(구어 실행증 2명, 브로카실어증 3명, 명칭 실어증 1명)과 보호자들을 연구 대상으로 선정하였다. 명확한 정보교환 의사소통은 보호자가 촉진전략을 사용하여 환자의 메시지를 파악하였는지 알아보고 사회적 상호작용 의사소통은 보호자의 긍정적인 행동과 방해하는 행동의 빈도 변화를 파악하였다. 보호자의 행동 변화는 훈련 전의 부정적 행동들이 훈련 후 어떠한 행동으로 변화하였는지 알아보고 설문지를 통해 환자와 보호자들의 만족도를 알아보았다. 결과 : 첫째, 보호자 교육과 경험학습에 근거한 그룹훈련이 명확한 정보교환 의사소통을 향상 시켰다. 둘째, 보호자 교육과 경험학습에 근거한 그룹훈련이 사회적 상호작용 의사소통을 향상 시켰다. 셋째, 보호자 교육과 경험학습에 근거한 그룹훈련이 보호자의 행동을 변화시켰다. 넷째, 보호자 교육과 경험학습에 근거한 그룹훈련이 환자와 보호자들의 만족도를 향상 시켰다. 결론 : 본 연구를 바탕으로 하여 국내에서는 그동안 거의 고려되지 않았던 실어증 환자의 보호자 교육에 대한 중요성을 깨닫고, 국외에서 이미 활용 중인 여러 유형의 프로그램을 표방하여 우리나라의 문화와 재활 환경에 맞는 다양한 보호자 교육의 내용을 계획할 필요가 있다.

• 혜화의학회지
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• 제16권1호
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• pp.181-189
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• 2007

Objectives : The purpose of this study is to search for more effective methods of diagnosis and treatment of Communication Disorder with Post-Stroke. Methods : Literature review on Communication Disorder with Post-Stroke in view of oriental and western medicine. Conclusions : Communication Disorder with Post-Stroke is relative with aphasia in western medicine, Sul-um(舌瘖) oriental medicine Aphasia, apraxia of speech, and dysarthria come after strock Each of them has its own mechanism. Yomchon(CV23), Amun(GV15), Chuldol(CV22), Tongni(HT5), Pungnyung(ST40), Pungbu(GV16), Chigu(TE6), Yongchon(KI1), Hapkok(L14), Peakoe(GV20), Kokchi(LI11), Puryu(KI7), Shinsu(BL23), Kumjin-okaek, and Chohea(KI6) was used on Communication Disorder with Post-Stroke treatment.