Journal of the Korean neurological association (대한신경과학회지)

Korean Neurological Association (대한신경과학회)
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Familial Creutzfeldt-Jakob Disease with V180I Mutation Presented with Broca's Aphasia

브로카실어증으로 발현한 가족성 V180I 변이 Creutzfeldt-Jakob병

  • Kim, Jeongyeon (Department of Neurology, College of Medicine, Dong-A University) ;
  • Lee, Deok-Soo (Department of Neurology, College of Medicine, Dong-A University) ;
  • Park, Kyung Won (Department of Neurology, College of Medicine, Dong-A University)
  • 김정연 (동아대학교 의과대학 신경과학교실) ;
  • 이덕수 (동아대학교 의과대학 신경과학교실) ;
  • 박경원 (동아대학교 의과대학 신경과학교실)
  • Received : 2018.06.14
  • Accepted : 2018.08.10
  • Published : 2018.11.30
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Abstract

Familial Creutzfeldt-Jakob Disease (fCJD) is characteristic with older age onset, relatively low occurrence rate, slower progression and lower possibility of developing myoclonus, cerebellar, pyramidal signs and visual disturbance compared with classical sporadic CJD. We report a case of 75-year-old male patient presented with sudden onset of right side weakness with Broca's aphasia who has been diagnosed with fCJD with V180I mutation. This case indicates that fCJD with V180I mutation can have stroke-like initial presentation.

Keywords

References

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