• Title/Summary/Keyword: VAC

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Successful Treatment of Infantile Fibrosarcoma Spinal Metastasis by Chemotherapy and Stereotactic Hypofractionated Radiotherapy

  • Lo, Cheng-Hsiang;Cheng, Shin-Nan;Lin, Kuen-Tze;Jen, Yee-Min
    • Journal of Korean Neurosurgical Society
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    • v.54 no.6
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    • pp.528-531
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    • 2013
  • We report a case of infantile fibrosarcoma in an 8-month-old boy manifested as a right-sided lower leg mass. Repeated local recurrence and distant metastasis were noted during the following three-year period. Whole body fluoro-deoxyglucose positron emission tomography scan revealed an asymptomatic metastasis involving the fourth lumbar vertebrae. The patient received chemotherapy (VAC regimen) with Cyberknife$^{(R)}$ stereotactic hypofractionated radiotherapy (26 Gy; 4 fractions). This treatment reduced tumor size by 23% without acute radiation toxicity even after 33 months. This case suggests that combining chemotherapy and this form of radiotherapy may be safe and effective against childhood spinal metastasis.

Comparative Proteome Analysis of Celastrol-Treated Helicobacter pylori

  • Kim, Sa-Hyun
    • Biomedical Science Letters
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    • v.23 no.4
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    • pp.395-401
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    • 2017
  • Various preclinical and clinical trials have been conducted the efficacy of celastrol. In data presented in the current manuscript is the first trial to inhibit Helicobacter pylori with celastrol. In this study, the quantitative change of various H. pylori proteins including CagA and VacA by the anti-bacterial effect of celastrol was determined. The anti-H. pylori effects of celastrol was investigated by performing 2-dimensional electrophoresis and additional supporting experiments. After 2-dimensional electrophoresis analysis, spot intensities were analyzed and then each spot was identified using matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF-MS) or peptide sequencing using Finnigan LCQ ion trap mass spectrometer (LC-MS/MS). The results show that celastrol has multiple effects on protein expression in H. pylori.

Analysis of High Vacuum System Based on the Applications of Vacuum Materials

  • Kim, Hyung-Taek
    • Transactions on Electrical and Electronic Materials
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    • v.14 no.6
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    • pp.334-338
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    • 2013
  • In this study, the outgassing effects of selected vacuum materials on the vacuum characteristics were simulated by the $VacSim^{Multi}$ simulation tool. This investigation examined the feasibility of reliably simulating the outgassing characteristics of common vacuum chamber materials (aluminum, copper, stainless steel, nickel plated steel, Viton A). The optimum design factors for these vacuum systems were suggested based on the simulation results. The baking-out effects of the modeled systems and materials on the performance of the vacuum system were also analyzed. The simulation predicted that the overall outgassing effect was more significant in the turbomolecular pump system than in the diffusion pump system and that the utilization of a booster pump has a greater effect on the evacuation time than on the ultimate pressure.

A Study on the Circuit Breaker Life-cycle Decision-making for the 480 Vac Distribution System (원전 저전압 분배계통 차단기의 수명관리 의사결정 사례)

  • Lim, W.S.;Ha, C.W.;Han, S.H.
    • Proceedings of the KIEE Conference
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    • 2009.07a
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    • pp.668_669
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    • 2009
  • 상업운전이 개시된 이래 24년이 경과한 원자력발전소의 480V 저전압분배계통 차단기의 설비특성, 운전 및 정비경험, 현행 정비활동, 경년열화, 성능, 단종 분야를 검토하여 480V 저전압분배계통 차단기에서 제기될 수 있는 현안사항과 이를 해결하기 위한 일련의 수명관리계획을 도출하는 기술성 평가를 수행하였다. 기술성 평가를 통해 제시된 일련의 수명관리계획안에 대하여 비용 및 고장률 데이터를 근거로 EPRI의 LcmVALUE 프로그램을 이용하여 경제성을 분석하고 480V 저전압분배계통차단기의 최적 수명관리계획과 권고사항을 제시하였다.

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A Study on the Insulation Resistance Measurement Technique for Electrical Safety of Green Car (친환경자동차의 전기안전을 위한 절연저항 측정에 관한 연구)

  • Lee, Ki-Yeon;Kim, Dong-Ook;Kim, Hyang-Kon;Moon, Hyun-Wook
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.58 no.4
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    • pp.597-601
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    • 2009
  • Green car such as a hybrid electrical vehicle and fuel cell vehicle is developed as a commercial target. UN/ECE/WP29 is developing GTR of HFCV and establishing the regulation and standard of electrical safety by ELSA. The regulation and standard about Electrical safety of vehicle are prescribed in ISO, UN/ECE, FMVSS, Japanese Attachment and so on, in case of insulation resistance is referred to keep more than 100/Vdc, 500/Vac. However, accurate method to measure insulation resistance agreeable to structure of vehicle does not exist now, it is actually that correctness of measurement drops according to the feature of battery and fuel cell stack. In this paper, the method to measure insulation resistance for protection against electrical shock by direct contact or indirect contact in Green Car will be indicated by making a comparison between the insulation measurement in standard of electrical safety and the experiment results for HEV and HFCV.

Linear Dielectric Relaxations in Copolymers of Vinylidence Cyanide (VDCN계(系) 공중합체(共重合體)의 선형(線刑) 유전특성(誘電特性))

  • Kang, Dae-Ha;Lee, Duck-Chool
    • Proceedings of the KIEE Conference
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    • 1988.11a
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    • pp.186-188
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    • 1988
  • Relaxation spectra of the linear dielectric constants $\varepsilon=\varepsilon'-j{\varepsilon}"$ have been measured as functions of temperature and frequency for alternating copolymers of vinylidene cyanide (VDCN/VAc, VDCN/VPr, VDCN/VBz and VDCN/St) It is found that the linear dielectric constants e show characteristics of the temperature dependence that the real part have a large peak related to the glass transition point(Tg), and of the frequency dependence that the real port increases with decreasing frequency and the imaginary part increases largely in low frequency range. These phenomena mean Debye-type relaxation due to the micro-Brownian moi ions of non-crystalline seqments.

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Simulation of Conductance Effects on Vacuum Characteristics of High Vacuum System for Semiconductor Processing (반도체공정 고진공시스템 진공특성에 대한 배기도관 컨덕턴스 영향 전산모사)

  • Kim, Hyung-Taek;Seo, Man-Jae
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.23 no.4
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    • pp.287-292
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    • 2010
  • Effect of conductance factors on performance of vacuum system was simulated for optimum design of vacuum system. In this investigation, the feasibility of modeling mechanism for VacSim$^{Multi}$ simulator was proposed. Application specific design of vacuum system is required to meet the particular process conditions for various industrial implementations of vacuum equipments. Geometry and length, diameter of exhaust pipeline were modeled as simulation modeling variables for conductance effects. Series vacuum system was modeled and simulated with varied dimensions and structures of exhaust pipeline. Variation of pipeline diameter showed the more significant effects on vacuum characteristics than that of pipeline length variations. It was also observed that the aperture structure of pipeline had the superior vacuum characteristics among the modeled systems.

Simulation of Modeling Characteristics of Pumping Design Factor on Vacuum System

  • Kim, Hyung-Taek;Cho, Han-Ho
    • International journal of advanced smart convergence
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    • v.5 no.2
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    • pp.1-7
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    • 2016
  • Recently, with the development of advanced thin film devices comes the need for constant high quality vacuum as the deposition pressure is more demanding. It is for this reason our research seeks to understand how the variable design factors are employed in such vacuum systems. In this study, the effects of design factor applications on the vacuum characteristics were simulated to obtain the optimum design modeling of variable models on an ultra high vacuum system. The commercial vacuum system simulator, $VacSim^{(multi)}$, was used in our investigation. The reliability of the employed simulator was verified by the simulation of the commercially available models of ultra high vacuum system. Simulated vacuum characteristics of the proposed modeling aligned with the observed experimental behavior of real systems. Simulated behaviors showed the optimum design models for the ideal conditions to achieve optimal pressure, pumping speed, and compression ratio in these systems.

Production and Operating Characteristics for Inorganic EL Phosphor (무기EL용 형광체 제작 및 구동특성)

  • Chansri, Pakpoom;Lee, Don-Kyu;Gwak, Dong-Joo;Sung, Youl-Moon
    • Proceedings of the KIEE Conference
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    • 2015.07a
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    • pp.1132-1133
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    • 2015
  • In this paper, we are presents production and operation characteristics for inorganic EL phosphors device using screen printed. The EL device is composed as ITO PET / EL phosphors dielectric $(2{\times}2cm^2)/TiO^2$ paste/Ag electrode. At 100Vac 400Hz, the luminescence of inorganic EL phosphors were $60.33cd/m^2$ of red phosphor, $42.12cd/m^2$ of green phosphor and $58.45cd/m^2$ of blue phosphor. The output current was 12.57 mA, 17.11 mA and 11.98 mA, respectively. The inorganic EL phosphors of EL device are increasing efficiency EL device.

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A Multilevel Inverter Using DC Link Voltage Combination (DC링크 전압 조합을 이용한 멀티 레벨 인버터)

  • Joo S.Y.;Lee J.H.;Kang F.S.;Kim C.U.;Park S.J.
    • Proceedings of the KIPE Conference
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    • 2003.07b
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    • pp.621-624
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    • 2003
  • In this paper, a novel multilevel inverter using DC-Link voltage combination is presented to reduce the harmonics of output voltage without the output filter inductor. The proposed multilevel inverter can generate 27-level output voltage. It employs three H-bridge cells which consist of single phase full-bridge inverter module. As well as, it can make continuous output voltage level employing the properly three DC-Link voltage ratio. The validity of the proposed inverter is verified through the experimental result using a prototype which can generate a 110[Vac], 60[Hz] output voltage from 12[Vdc], 36[vdc], and 108[Vdc] input voltages

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