Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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Successful Treatment of Infantile Fibrosarcoma Spinal Metastasis by Chemotherapy and Stereotactic Hypofractionated Radiotherapy

  • Lo, Cheng-Hsiang (Department of Radiation Oncology, Tri-Service General Hospital, National Defense Medical Center) ;
  • Cheng, Shin-Nan (Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center) ;
  • Lin, Kuen-Tze (Department of Radiation Oncology, Tri-Service General Hospital, National Defense Medical Center) ;
  • Jen, Yee-Min (Department of Radiation Oncology, Tri-Service General Hospital, National Defense Medical Center)
  • Received : 2013.01.10
  • Accepted : 2013.12.10
  • Published : 2013.12.28
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Abstract

We report a case of infantile fibrosarcoma in an 8-month-old boy manifested as a right-sided lower leg mass. Repeated local recurrence and distant metastasis were noted during the following three-year period. Whole body fluoro-deoxyglucose positron emission tomography scan revealed an asymptomatic metastasis involving the fourth lumbar vertebrae. The patient received chemotherapy (VAC regimen) with Cyberknife$^{(R)}$ stereotactic hypofractionated radiotherapy (26 Gy; 4 fractions). This treatment reduced tumor size by 23% without acute radiation toxicity even after 33 months. This case suggests that combining chemotherapy and this form of radiotherapy may be safe and effective against childhood spinal metastasis.

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References

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