• Title/Summary/Keyword: The Young

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Clinicopathological and p53 Gene Alteration Comparison between Young and Older Patients with Gastric Cancer

  • Karim, Sajjad
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.3
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    • pp.1375-1379
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    • 2014
  • Background: Differences in clinicopathological characteristics of gastric cancer (GC) between young and older patients are controversial and a matter of debate. Determining the statistical significance of clinicopathological information with respect to age might provide clues for better management and treatment ofGC. Materials and Methods: A total ofl03 Indiao GC patients were enrolled for study and specimens were classified according to the AjCC-TNM system. Patients were grouped into two age-wise categories, young patients (<40 years; n=13) and older patients (${\geq}40$ years, n=90). The clinicopathological features of both groups were retrospectively examined and compared. p53 alterations were analyzed by polymerase chain reaction-single strand conformational polymorphism and immunohistochemistry methods at gene and protein levels respectively. The cases were considered p53 over-expressed if it was present in more than 25% of the tumor cells and p53 alterations was correlated with the clinicopathological characteristics of the patients as well as etiological factors for GC in both groups. Results: We found significant association of young patients with cancer stage (p=0.01), and very strong association with histology grade (p=0.064) and poorly differentiated (p=0.051) state of GC. However, neither young nor elderly patients showed associations with location, gender, etiological factors and p53 expression and alteration. Overall the male-to-female ratio of GC patients was 3.12 and the value was higher in the young (5.5) than in the older group (2.91). Conclusions: Clinicopathological features of GC like caocer stage, cell differentiation and histological grades were significantly different among young and old age cohorts. We observed a male predominance among the young group that decreased significantly with advancing age. More awareness of GC onset is required to detect cancer at an early stage for successful treatment.

Relationships between the sensory, cognitive and physical functions of young-old and old-old individuals (전·후기 노인들의 감각기능, 인지기능과 신체기능 간의 관련성)

  • Jeon, So-Youn;Lee, Sok-Goo
    • Korean Journal of Health Education and Promotion
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    • v.33 no.5
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    • pp.23-36
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    • 2016
  • Objectives: This study aims to define the relationships between the sensory, cognitive and physical functions of young-old and old-old individuals. Methods: Participants were 10,451 elderly individuals aged 65 and above, raw data of a 2014 National Survey on Korean Older Persons was used. To investigate the relationships among the sensory, cognitive, and physical functions, a structural equation model was used. Results: The key analysis results are summarized as follows; 5% had poor vision function(young-old 3.5%, old-old 7.1%), 3.8% had poor auditory function(young-old 1.7%, old-old 6.7%), 33.0% had decline in cognitive function(young-old 30.9%, old-old 35.7%), 3.6% were disabled(young-old 1.6%, old-old 6.3%) and cognitive function influences physical function more greatly than does sensory function. Additionally, in the young-old groups, vision among sensory functions, attention among cognitive functions, and IADL among physical functions, turned out to be the most influential. However, in the old-old groups, auditory function among sensory functions, orientation among cognitive functions, and IADL among physical functions, turned out to be the most influential. Conclusions: This study implies that functions in the young-old and old-old individuals must be considered with all three functions-sensory, cognitive, and physical-together at the same time and that this comprehensive approach is necessary in national policy making.

Clinical Analysis of Stroke in Young Adults (청장년층 뇌졸중에 대한 고찰)

  • 정은정;배형섭;문상관;고창남;조기호;김영석;이경섭
    • The Journal of Korean Medicine
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    • v.21 no.1
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    • pp.84-90
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    • 2000
  • Background and Purpose: Stroke in young adults is relatively uncommon. Only 3.7-14.4% of all strokes occur in patients aged 15-45 years. Stroke in young adults has more various and diverse possible causes than stroke in the elderly. We studied to gain further insight into both pathogenic and etiologic determinants in young adults with stroke. Methods : We retrospectively reviewed the medical records of 230 young patients aged 15-45 years who were admitted to the 2nd internal medicine department of Kyung Hee Oriental Medical Center with a diagnosis of stroke between May 1995 and May 1999. We analysed clinical features and diagnostic tests, such as brain imaging, cerebral angiography, echocardiography, 24 hours holter monitoring and other laboratory tests. Results : 1. Of 230 young patients with stroke aged 15-45 years(176 males(76.5%) and 54 females(23.5%)), 140 patients(60.9%) showed ischemic stroke and 90 patients(39.1 %) showed hemorragic stroke. 2. The most prevalent age group was from 40 to 45 years with 142 patients(61.7%) 3. The most frequent site of 140 ischemic stroke was MCA territory in 93 cases(66.4%) and Multiple, VA territory, PCA territory, ACA territory in order of frequency. 4. The most frequent site of 90 hemorrhagic stroke was basal galglia hemorrhage 57 cases(63.3%) and subcortical 13 cases(14.5%), pons, thalmus, subarachnoid, cerebellum in order of frequency. 5. The causes of hemorrhagic stroke were hypertension 49 cases(54.5%), arteriovenous malformation 7 cases(7.8%), ruptured aneurysm 4 cases(4.5%), angioma 3 cases(3.3%). 6. The risk factors of ischemic stroke were smoking, alcohol drinking, hyperlipidemia, hypertension, obesity, heart disease, history of CVA, diabetes mellitus, in order of frequency. 7. The comparison of risk factors between ischemic and hemorrhagic stroke: hypertension was prevalent in hemorrhagic stroke, heart disease and history of CVA were prevalent in ischemic stroke. Conclusions: From the above results, we found that stroke in young adults had various possible causes. Young adults with stroke deserve an extensive but tailored evaluation which include angiography and echocardiography for diagnosis.

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The Effects of Father Marital Satisfaction on Young Child Emotion Regulation: Mediating Effects of Father Parenting Participation (아버지의 결혼만족도가 유아의 정서조절능력에 미치는 영향: 아버지의 양육참여도의 매개효과)

  • Yoon, Mi Sun;Kim, Misuk
    • Korean Journal of Child Studies
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    • v.37 no.3
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    • pp.111-122
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    • 2016
  • Objective: The purpose of this study was to investigate the association between father marital satisfaction and parenting participation and young child emotion regulation to determine the mediating effects of father marital satisfaction and parenting participation on young child emotion regulation. Methods: This study was conducted with 249 3-, 4-, and 5-year-olds and their fathers at nurseries in Seoul and Gyeonggi. The collected data were analyzed via frequency, average, standard deviation, Pearson's correlation analysis, Baron and Kenny's hierarchical regression analysis, and the Sobel test. Results: First, father marital satisfaction, parenting participation and young child emotion regulation, including the sub-factors of each variable, were all significantly correlated. Second, father parenting participation was found to have a full-mediating effect emotion regulation of the young child. Meanwhile, father parenting participation was found to have a full mediating effect others-regulation of the young child. In addition, father parenting participation was found to have a partial mediating effect on young child self-regulation. Conclusion: These results suggests the need to provide more practical family programs and realistic governmental support to promote father parenting participation.

Effects of Childcare Teacher's Self-Efficacy and Teacher - Child Relationship on Young Children's Adjustment to Childcare Centers - (보육교사의 교사효능감과 교사 - 유아관계가 유아의 보육시설 적응에 미치는 영향 -)

  • Kim, Young-Hee;Kang, Gi-Sook;Han, Sae-Young
    • Journal of the Korean Home Economics Association
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    • v.46 no.5
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    • pp.73-86
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    • 2008
  • The purpose of this study was to investigate the effect of teachers' self-efficacy and teacher-child relationship on young children's adaptation to childcare centers, and to examine the interaction effects of teachers' self-efficacy and teacher-child relationship on young children's adjustment to childcare centers. The subjects of this study were 360, three- to four-year-old who attended childcare centers located in Chungbuk province and their 72 teachers. The results of this research indicated that the main effect of teachers' self-efficacy and the main effects of familiarity and conflicts between teachers and children on young children's adjustment to childcare centers were significant. The interaction effects of teachers' general efficacy and conflicts or familiarity between teachers and children on young children's adjustment to childcare centers were also significant.

The Reciprocal Relationship Between Young Children's Vocabulary Ability and Physical Aggression: A Longitudinal Study Using Autoregressive Cross-lagged Modeling (유아기의 어휘력과 신체적 공격성 간의 상호 영향: 자기회귀교차지연모형을 활용한 종단연구)

  • Han, Sae-Young;Joo, Ji-Yeong
    • Korean Journal of Childcare and Education
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    • v.15 no.5
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    • pp.23-45
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    • 2019
  • Objective: The purpose of this study is to identify the longitudinal reciprocal relationship between young children's vocabulary ability and physical aggression in young children. Methods: Two waves of panel data(2013/2015) from the Panel Study of Korean Children were analyzed in this study by using an adapted version of Autoregressive cross-lagged modeling. A total of 306 five-year-old and seven-year-old preschoolers, and their mothers participated in the study. Autoregressive cross-lagged modeling for multiple groups was conducted by using AMOS 24.0. Results: First, vocabulary ability and physical aggression showed stability over time. Second, young children's vocabulary ability(t) had a statistically significant effect on physical aggression(t+1). Conclusion/Implications: This study confirmed the interrelationships of young children's vocabulary ability and physical aggression by examining longitudinal data using the longitudinal analysis method. This study highlights the importance of developing interventions to support language development with aggressive children. The results of the present study can be used as a source in developing policies for aggressive children and their parents.

Social and Cognitive Play Patterns in Terms of Young Children's Cognitive Styles (유아의 장독립성-장의존성 인지양식에 따른 사회, 인지적 놀이형태에 관한 연구)

  • Cho, Boo Kyung;Jang, Sun Hwa
    • Korean Journal of Child Studies
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    • v.16 no.1
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    • pp.49-64
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    • 1995
  • The purpose of this study was to investigate differences in social play, cognitive play, and social-cognitive play patterns as related to young children's field independence-dependence cognitive styles. Sixteen field independent and sixteen field dependent children were selected from a group of 79 young children with the use of Preschool Embedded Figures Test(PEFT). Their social play, cognitive play, and social-cognitive play patterns were observed. The data collected for this study were analyzed by using SPSS/$PC^+$; frequency, percentage and ${\chi}^2$ test. The results of this study were that (1) difference of social play patterns as related to young children's field independence-dependence cognitive styles was not found, (2) differences were found in cognitive play patterns as related to young children's field independence-dependence cognitive styles, and (3) differences were found in social-cognitive play pattern as related to young children's field independence-dependence cognitive styles.

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Effects of Mother's Affectionate Parenting, Psychological·Behavioral Control on Young Children's Problem Behaviors: Mediating Effect of Self-control (어머니의 애정적 양육행동과 심리·행동 통제가 유아의 문제행동에 미치는 영향: 자기통제의 매개효과)

  • Sung, Hey won;Han, Sae Young
    • Korean Journal of Childcare and Education
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    • v.11 no.4
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    • pp.271-292
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    • 2015
  • The purpose of this study was to examine the mediating effect of young children's self-control in the relationship between mother's affectionate parenting psychological behavioral control and young children's problem behaviors. The subjects of this study were 368 mothers whose young children were 3 to 5years old and attending to 3 private kindergartens and 2 child-care centers located in Chunkbuk. Data were analyzed by frequency, percentage, Primary factor analysis, Cronbach's ${\alpha}$, t-test, F-test, Pearson's correlation, and hierarchical regression, using the SPSS 12.0 program. The results of this study were as follows: First, young children's self control partially mediated when mother's affectionate parenting affected young children's internalizing and externalizing problem behaviors. Second, young children's self control partially mediated when mother's psychological control affected young children's internalizing and externalizing problem behaviors. Third, young children's self control did not show a mediating effect on the relationship between mother's behavioral control and young children's internalizing and externalizing problem behaviors. In conclusion, young children's internalization of mother's psychological control and behavioral control as well as affectionate parenting have its effect on problem behaviors.

The Effects of Maternal Parenting, Teacher-Child Closeness Relationships and Effortful Control on Young Children's Leadership (어머니의 양육행동과 교사-유아 친밀 관계 및 유아의 의도적 통제가 리더십에 미치는 영향)

  • Lee, Kyung Nim
    • Korean Journal of Childcare and Education
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    • v.11 no.6
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    • pp.19-36
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    • 2015
  • This study examined the effects of young children's effortful control, maternal parenting and teacher-child closeness relationship on young children's leadership. The subjects of this study were 266, 4-5 year old children and their mothers and teachers. Young children's effortful control, maternal parenting, teacher-child relationship and leadership were assessed by mother's and teacher's report. The collected data were analyzed by means of Pearson's correlation and pathway analysis. The results were as follows: first, teacher-child closeness relationship was found to affect young children's leadership directly and indirectly through young children's effortful control. Second, maternal parenting was found to affect young children's leadership indirectly through young children's effortful control. Third, young children's effortful control was found to affect leadership directly and to have a mediating effect between maternal parenting and young children's leadership, and between teacher-child closeness relationship and young children's leadership. Additionally teacher-child closeness relationship was found to be the most important variable predicting young children's leadership. These findings suggest that teacher-child closeness relationship could be the most important means by which we could improve both young children's effortful control and leadership.

A Study on mine drainage characteristcs as abandoned Coal mine in Gyeongsang province (경상도 일대의 폐탄광 갱내수의 수질 특성 연구)

  • Jung, Young-Kook;Hong, Ji-Hye;Lee, Dong-Jin;Kim, Jeong-Phill;Kim, Dae-Gi;Joo, Sang-Don
    • Proceedings of the Korean Geotechical Society Conference
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    • 2008.10a
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    • pp.1440-1445
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    • 2008
  • There are 21 abondoned coal mines drained out mine water in gyeong sang do. We monitored the water quality of 31 mine drainage from 1995. The most of mine drainage was neutral as the average pH was 6.22 and Fe, Mn, Al concentration was below 10mg/L. The result showed the tendency of decreasing of flow and metal concentration. The highest Mn concentration was detected in bonghwa area and the hightest Fe concentration was detected in munkyung area. It means that the water quality is closly related to geological features.

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