• Title/Summary/Keyword: Specialized Research Institute

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The Pleiotropy of Telomerase against Cell Death

  • Sung, Young Hoon;Choi, Yoon Sik;Cheong, Cheolho;Lee, Han-Woong
    • Molecules and Cells
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    • v.19 no.3
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    • pp.303-309
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    • 2005
  • The end of eukaryotic genomic DNA is capped by a specialized structure called as "telomere" which consists of the repetitive array of nucleotide sequence, TTAGGG, in humans and mice, and a variety of binding proteins. Telomerase is a ribonucleoprotein (RNP) complex responsible for the elongation of telomeres to maintain the genomic integrity, and is composed of telomerase reverse transcriptase (TERT), telomerase RNA component (TERC), and their associated factors regulating the catalytic activity of telomerase. Although it is now apparent that telomerase protects cells from apoptosis via the maintenance of genomic integrity by stabilizing telomeres, our understanding for the physiological role of telomerase is yet far from completion, and emerging evidence suggests that telomerase has additional extratelomeric roles in mediating cell survival and anti-apoptotic functions against various cytotoxic stresses. Here we summarize and discuss how telomerase and telomeres are involved in mediating cellular protection against apoptosis.

Validity assessment for competency development in clinical dental hygiene education based on dental hygiene process of care (치위생과정에 기반한 임상치위생학 교육과정 역량 개발을 위한 타당도 평가)

  • Jin-Sun Choi;Sun-Jung Shin;Bo-Mi Shin;Hyo-Jin Lee;Hye-Young Yoon;Soo-Myoung Bae
    • Journal of Korean society of Dental Hygiene
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    • v.24 no.1
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    • pp.45-56
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    • 2024
  • Objectives: Before implementing a competency-based clinical dental hygiene curriculum, it is essential to establish competency development as a foundational educational objective. Therefore, this study aimed to develop the competency of clinical dental hygiene with secured validity using the Delphi survey method. Methods: Dental hygiene competencies were categorized within the dental hygiene process stages, and questions were formulated accordingly. A Delphi survey involving ten qualified experts was conducted to refine the final items based on their review opinions. Results: The expert Delphi survey confirmed that all items met stability criteria, with CVI values of 0.80 or higher, CVR values of 0.60 or higher, and a CV coefficient of variation of 0.5 or less. In total, 42 items were derived. Conclusions: Clinical dental hygiene can contribute to developing specialized dental hygienists if the competencies derived from this study are well applied to the standardized curriculum and operations.

The Effect of Resilience in Career Decision-Making among Specialized Technical High School Students (특성화고등학교 학생의 회복탄력성이 진로결정 자기효능감에 미치는 영향)

  • Park, Najeong;Lim, Nhayoung;Lee, Chang-Hoon
    • 대한공업교육학회지
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    • v.43 no.1
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    • pp.20-40
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    • 2018
  • This study examined resilience and career decision-making among specialized technical high school students with the aim of proposing preliminary data to suggest ways to improve self-efficacy in career decision-making through establishing proper resilience. The specific research questions were set as; first, to define the resilience status in relation to the students' personal characteristics among students; second, to describe the status of self-efficacy in career decision-making related to the students' personal characteristics among students; and last, to examine the influence of resilience on self-efficacy in career decision-making among specialized technical high school students. To accomplish such research objectives, the assessment survey was developed after reviewing the theoretical literature on specialized technical high school students' background, ego identity, and self-efficacy in career decision-making. The survey was comprised of 54 items including personal characteristics (3 items), resilience (27 items), and self-efficacy in career decision-making (24 items). A total of 990 students from industrial specialized high schools across the country completed the survey, and the responses from 775 students were used for the final analyses after excluding the surveys with unanswered items or untrustworthy responses. Results were as follows: The group with higher levels of school adaptation and satisfaction showed higher resilience and career decision-making than those with lower levels of school adaptation and satisfaction. Furthermore, for the influence of resilience on self-efficacy in career decision-making, the results showed that resilience had positive associations with self-efficacy in career decision-making, and all correlations and coefficients of determination showed a robust statistical significance. Therefore, to enhance self-efficacy in career decision-making, education that could help students better adapt to school, increase satisfaction with the school, and create positive resilience must precede.

Relationships of Achievement Goal Orientation with Academic Self-efficacy of Specialized High School Students (특성화고등학교 학생의 성취목표지향성과 학업적 자기효능감의 관계)

  • Yang, Jin-Sik;Song, Nak-Hyun;Lee, Chang-Hoon
    • 대한공업교육학회지
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    • v.43 no.2
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    • pp.79-96
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    • 2018
  • In this study, we look at the effect that the achievement goal of specialized high school students has on academic self-efficacy and the difference in academic self-efficacy depending on achievement goal orientation. The purpose of this research is to help students to efficiently increase their academic self-efficacy, develop research and study life guidance measures to improve negative factors, and select professors and learning methods. To achieve the purpose, survey was conducted with achievement goal orientation measurement tools(26 questions) and academic self-efficacy measurement tools(28 questions) for 745 students of 18 specialized technical high school students in 5 districts. The results of this study are as follows. First, preference to task difficulty and self-controlling efficacy have highly positive correlations with mastery goal orientation and confidence and mastery avoidance goal orientation have highly negative correlations each other. Second, achievement goal orientation form of specialized high school students were divided into 5 forms; 'execution avoidance(34.8%)', 'mastery orientation(20.8%)', 'approach(17%)', 'avoidance competition(14.9%)', and'mastery avoidance(12.5%)'. In preference to task difficulty, 'approach'group showed the highest average point and 'mastery avoidance'showed the lowest average point. The average point of 'approach' group was higher than other groups in confidence, but 'mastery orientation' group showed the highest average point. Through the results of this study, academic self-efficacy makes an effect by a certain direction in accordance with achievement goal orientation and it's necessary to access academic problems differently according to student's goal directivity. Therefore, it's necessary to provide educational method by student type based on explanation about academic self-efficacy of achievement goal orientation of specialized high school students and analysis on achievement goal orientation form.

A Theory on the Scope of Financial Activity (금융(金融)의 전업(專業) 및 겸업화(兼業化) 이론(理論): 금융산업조직론(金融産業組織論)의 모색(摸索))

  • Jwa, Sung-hee
    • KDI Journal of Economic Policy
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    • v.13 no.1
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    • pp.167-197
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    • 1991
  • This paper is intended as an introductory essay to explain endogenous changes in the scope of firm activities in the competitive structure of a deregulated, multi-product financial industry. Recently, the global financial industry has been experiencing a widespread reshuffling in its activities, reflecting both consolidation and specialization. The spread of the universal banking system, which involves the integration of various kinds of financial activities, has resulted in the so-called financial supermarket. At the same time, the traditional set of banking activities has been unbundled into so-called financial boutiques. A relevant question is where the current reshuffling process of integration and disintegration in financial activities might lead the financial industry. However, presently popular theories of the financial industry are not really appropriate for the analysis of this issue. This paper attempts to integrate the theory of specialization [George J. Stigler, "The Division of Labor is Limited by the Extent of the Market," Journal of Political Economy, Vol. LIX, No.3, June 1951] and the theory of the multi-product firm [William J. Baumol, John C. Panzar, and Robert D. Willig, Contestable Markets and the Theory of Industry Structure, Harcourt Brace Jovanovich, Inc., New York, 1982] and to apply the resulting hybrid theory, a theory on the scope of financial activity, to the financial industry. The implications of this theory for the issues raised above are formalized under five hypotheses on the reshuffling of financial activities as listed below: Hypothesis I: The differences in the organization of financial industries among countries are determined by differences in the size of the financial markets, other things being equal. Hypothesis II: A financial firm will separate those financial activities simultaneously having relatively strong economies of scale and relatively weak economies of scope (alternatively, diseconomies of scope) from other activities. Conversely, the firm will integrate those activities simultaneously having relatively weak economies of scale (alternatively, diseconomies of scale) and relatively strong economies of scope with incumbent activities. Hypothesis III: A competitive equilibrium in the deregulated financial industry will consist of both specialized and multi-product financial firms, resulting in a mixed form of specialized and universal banking systems. Hypothesis IV: As world financial markets fully integrate and all countries consequently face this single, common world market, the financial structures of individual countries will become increasingly similar. Hypothesis V: A more universal banking system will dominate the deregulated financial industry in countries with relatively small financial markets, while a more specialized banking system will dominate in countries with relatively large financial markets. However, equilibrium will ultimately be mixed, with specialized and universal banks coexisting, as stated in Hypothesis III. Based on these hypotheses, this paper interprets the historical development of specialized vs. universal banking systems in major industrial countries as a process driven by the evolution of the financial market in each country - i.e. the change in the size of the financial market over time. In addition, this paper anticipates that the final equilibrium of the world financial industry, which is currently under the pressure of financial innovations and deregulation, will be a mixed equilibrium with both specialized boutiques and universal supermarket-type financial firms, instead of an exclusively specialized or universal banking system. Future research should seek continued theoretical elaboration and empirical verification of this paper's hypotheses.

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The Effect of Emotional Intelligence on School Adjustment of Specialized Vocational High School Students (특성화고등학교 학생의 정서지능이 학교적응에 미치는 영향)

  • Park, So-Hyeon;Song, Gyo-Won;Lee, Chang-Hoon
    • 대한공업교육학회지
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    • v.43 no.1
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    • pp.41-57
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    • 2018
  • The purpose of this study is to help research and application about effective strategies to improve school adjustment of students by investigating the influence of specialized vocational high school students' emotional intelligence on school adjustment. A survey was conducted to 760 engineering major students at the vocational high schools from 18 vocational high schools of 5 major metroplex. A questionnaire consists of measurement tool for emotional intelligence (40 questions) and one for school adjustment (20 questions). The findings of this study are as follows: First, students with high emotional intelligence showed a higher level of school adjustment than students with lower emotional intelligence, and they also has a higher standard in all sub factors of school adjustment, Second, it is found that the explanatory power of emotional intelligence on school adjustment is 33.6%. It means the higher the emotional intelligence of the students, the higher the school adjustment, so it can be seen that emotional intelligence might be one alternative that increases school adjustment for specialized vocational high school students. Furthermore, emotional intelligence shows the greatest explanatory power to peer relationship in school adjustment sub factors. This is showed that students with high emotional intelligence have good peer relationship than students with lower emotional intelligence relatively. Also, it can be known that school adjustment is high because the better peer relationship is, the higher self-efficacy, class immersion, resilience and so on are.

Study of teachers' understanding of terminology and their meaning differences in the realm of invention based on invention/patent specialized high school (발명.특허 특성화고등학교 교사의 발명 관련 용어 이해도 분석)

  • Sim, Young-Ki;Jo, Han-Jin;Kim, Tae-Hoon
    • 대한공업교육학회지
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    • v.39 no.1
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    • pp.209-226
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    • 2014
  • This study investigates invention and patent specialized high school teachers' understanding of terminology and their meaning differences in the realm of invention, career-specific, and freestyle Invention according to background variables. The population of this research consists of 333 teachers currently employed in invention and patent specialized high school and complete enumeration survey has been used. To analyze the terminology understanding and their meaning differences, total of 216 questionnaires have been collected and 211 of them (63.4%) were used, excluding the ones with insincere answers. The results of this study are as follows. First, in regard to invention, carrer-specific, freestyle Invention terminology understanding, established teachers showed higher results over new teachers. In addition, experienced teachers showed higher results over inexperienced teachers, and teachers with in-service training experiences showed higher results over the ones without. Second, when it came to understanding the terminology differences in the three realms, the new teachers showed higher results than the established teachers, inexperienced teachers over those with teaching experiences, and ones who have never taken any in-service training showed higher results than the ones with training experiences. The ones who answered 'don't know' regarding the meaning differences among terminology were established teachers over new teachers, experienced teachers over inexperienced teachers, and in-service training recipients over the ones without.

Effect of NFTM-TRIZ Model Based on Cooperative Learning on Creativity and Class Satisfaction (협동학습에 기반한 NFTM-TRIZ교수·학습모형 적용이 창의성과 수업만족도에 미치는 효과)

  • Yun, Il Lo;Kim, Bi Ryong;Lee, Kyu Nyo;Kim, So Yeon
    • 대한공업교육학회지
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    • v.45 no.1
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    • pp.20-41
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    • 2020
  • The purpose of this study is to explore ways to improve teaching and learning in specialized high schools by investigating the relationship between creativity and class satisfaction in classes using the NFTM-TRIZ model for specialized high school students. In order to achieve the purpose of the research, first, the differences between the applied effects, experiments, and control groups were analyzed when the NFTM-TRIZ model was applied. Second, when the NFTM-TRIZ model was applied, it was analyzed whether there was a significant difference in creativity and class satisfaction by group size. The conclusions of this study are as follows. First, as a result of comparing the preand post-tests of the experimental group and the control group applying the NFTM-TRIZ model through the t-test, the experimental group showed significant differences in creative spontaneity, identity, attachment, curiosity and class satisfaction. Second, in experimental groups with the NFTM-TRIZ model, the size of groups of 4 and 6, rather than the size of groups of 2, had positive effects on class satisfaction. Therefore, the NFTM-TRIZ model based on collaborative learning was effective as a teaching and learning method that promoted creativity and satisfaction of students in specialized high schools.

A study on river management based on the results from a survey of citizens (시민 인식기반의 하천관리 정책에 관한 고찰)

  • Lee, Seungsoo;Ryu, Munhyun;Kim, Ikjae;Choi, Hyoyeon;Ha, Yujeong
    • Journal of Korea Water Resources Association
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    • v.55 no.2
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    • pp.171-176
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    • 2022
  • Citizen perception is increasingly emphasized as one of the critical factors in establishing public policies including river management. Our results show that citizens expect integrated river management by specialized river management organization. We found that the river condition was perceived more negatively than the actual status of water quality and river ecosystem by citizens. The gap in perception implies that it is important to restore the reliability of river management. Therefore, it is necessary to encourage organizations with public trust to participate in river management. and credible river management policies should be established and implemented.

Design and Implementation of Agent-Recruitment Service System based on Collaborative Deep Learning for the Intelligent Head Hunting Service (지능형 헤드헌팅 서비스를 위한 협업 딥 러닝 기반의 중개 채용 서비스 시스템 설계 및 구현)

  • Lee, Hyun-ho;Lee, Won-jin
    • Journal of Korea Multimedia Society
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    • v.23 no.2
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    • pp.343-350
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    • 2020
  • In the era of the Fourth Industrial Revolution in the digital revolution is taking place, various attempts have been made to provide various contents in a digital environment. In this paper, agent-recruitment service system based on collaborative deep learning is proposed for the intelligent head hunting service. The service system is improved from previous research [7] using collaborative deep learning for more reliable recommendation results. The Collaborative deep learning is a hybrid recommendation algorithm using "Recurrent Neural Network(RNN)" specialized for exponential calculation, "collaborative filtering" which is traditional recommendation filtering methods, and "KNN-Clustering" for similar user analysis. The proposed service system can expect more reliable recommendation results than previous research and showed high satisfaction in user survey for verification.