• 대한한방내과학회지
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• 제26권3호
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• pp.543-550
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• 2005

This study was designed to identify the effects of Reynoutria Japonica on antibacterial activity aganist Bordetella pertussis ATCC 9797 which is cause of whooping cough. The ethanol- and water-extracts of more than 80 oriental herbal medicine were Investigated by Kirby -Bauer method to determine their inhibitory effects on growth of B. pertussis ATCC 9797 in vitro. For that Reynoutria Japonica was selected. The ethanol-soluble extract of Reynoutria Japonica showed relatively high antivacterial activity against B. pertussis ATCC 9797. However, the water-soluble extract of Reynoutria Japonica showed no antibacterial activity. The ethanolic extract was further fractionated with organic solvents such as hexane, chloroform, and ethyl acetate, in that order. Among the fraction tested, the chloroform fraction showed the highest antibacterial activity when the ethanol-soluble extract of Reynoutria Japonica minial inhibitory concentration(MIC) was $25{\mu}g/m{\ell}l$. Results support a role far Reynoutria Japonica in inhibiting the cell growth of B. pertussis ATCC 9797, but further experimentation is required.

• 한국환경복원기술학회지
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• 제17권3호
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• pp.53-63
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• 2014

This study was carried out to investigate the growth responses of medicinal plants such as Glehnia littoralis, Cryptotaenia japonica, Angelica gigas, Reynoutria japonica, Saururus chinensis, Houttuynia cordata, Ligularia fischeri, and Aralia cordata under 70%-shading and full sunlight conditions on a rooftop condition using artificial soil as a growth media. Glehnia littoralis, Cryptotaenia japonica, Ligularia fischeri, Saururus chinensis, and Houttuynia cordata showed better growth on plant height, leaf length, leaf width, petiole length and leaf number under full sunlight conditions on a rooftop condition. Cryptotaenia japonica and Houttuynia cordata had high value of Hunter's a (red-green) under full sunlight, while had lower value of L(lightness) and b(blue-yellow) than those of 70% shading condition. As an index of plant stress response, Glehnia littoralis, Reynoutria japonica, Houttuynia cordata, Ligularia fischeri showed Fv/Fm values 0.79~0.84 under full sunlight in August, indicating low stress on plant growth. Therefore they seemed to be suitable medicinal plats for rooftop conditions. Ligularia fischeri and Reynoutria japonica showed better growth under 70% shading treatment in August, while showed high growth response under full sunlight conditions in September. The 70% shading treatment was effective for the growth of Angelica gigas, Reynoutria japonica, and Aralia cordata. Angelica gigas and Reynoutria japonica, however, showed better plant growth under full sunlight during summer. The results showed that Glehnia littoralis, Cryptotaenia japonica, Ligularia fischeri, Saururus chinensis, and Houttuynia cordat seemed to be suitable medicinal plants for rooftop garden where there is a full sunlight condition.

• 한국자원식물학회지
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• 제28권6호
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• pp.743-751
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• 2015

Reynoutria japonica and R. sachalinensis have been used as medicinal resources in Korea. However, it is difficult to identify and determine these medicinal herbs correctly because they are usually customized and purchased as the fragmented rhizomes types. To develop molecular markers for distinguishing two species, we analyzed and compared the chloroplast DNA sequences of seven loci (atpB, matK, ccD-psaI, atpF-H, trnL-trnF, psbK-I and rpl32-trnL). Among them, we found two effective SNPs in psbK-I region for R. japonica and atpF-H region for R. sachalinensis. Based on these SNP sites, we designed the new R. japonica- specific primer which is able to amplify 300 bp fragment in psbK-I region. A similar strategy was applied for the atpF-H region of R. sachalinensis. These molecular markers would be successfully applied to recognize R. japonica and R. sachalinensis.

• 한국응용과학기술학회지
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• 제40권5호
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• pp.965-976
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• 2023

호장은 마디풀과에 속하는 다년초로 우리나라를 포함한 동아시아에서 잘 자생한다. 호장근은 호장의 뿌리로 항염증과 진경제로 사용되어 왔으며 유효성분으로 emodin을 포함하고 있다. 피부의 표피는 자극, 해로운 물질을 차단하고 수분 증발을 방지함으로써 체내를 보호하는 중요한 역할을 한다. 본 연구에서는 호장근과 그 유효성분인 emodin이 피부 장벽과 보습능에 미치는 영향에 대해 평가하고자 하였다. 먼저 호장근은 ABTS⁺ radicals을 우수하게 제거함으로써 항산화 효능이 뛰어남을 확인하였다. 다음으로, 실시간 중합연쇄효소반응을 통해 각질형성세포의 분화에 중요한 역할을 하는 filaggrin의 유전자 발현을 비교한 결과, 호장근과 emodin에 의해 농도-의존적으로 filaggrin mRNA 발현이 증가하였다. 또한, 호장근과 emodin은 히알루론산 합성에 중요한 역할을 하는 HAS-2 mRNA 발현을 유의하게 증가시키는 것으로 나타났다. 종합적으로, emodin을 유효성분으로 포함하는 호장근은 피부 장벽 강화와 보습능 증강을 위한 기능성 화장품 소재로서 활용될 수 있을 것으로 기대된다.

• 식물분류학회지
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• 제41권1호
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• pp.10-15
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• 2011

본 연구에서는 한국산 닭의덩굴속 호장근절 분류군들을 대상으로 개체군 수준에서 flavonoid 분석을 수행하여, 본 절 분류군에서 나타나는 형태변이 양상을 화학적 측면에서 파악하고, 이를 토대로 한반도에 분포하는 본 절 분류군들의 실체 및 한계를 정확히 파악하고자 하였다. 그 결과, 한국산 본 절 3분류군 15개체군의 잎으로부터 19종류의 서로 다른 flavonoid compound가 분리, 동정되었으며, 이들은 flavonol인 quercetin 및 kaempferol 3-O-glycoside들과 flavone인 apigenin및 luteolin C-glycoside들이었다. 이들 compound들 중 한국산 본 절 식물에 분포하는 주요 flavonoid compound는 quercetin 3-O-galactoside 와 quercetin 3-O-glucoside이었다. 본 절 한국산 분류군들은 그 flavonoid 조성에 의해 뚜렷이 구분되는 것으로 밝혀졌으며, 이러한 결과는 기존의 외부 형태학적 연구 결과와 전반적으로 일치하였다. 한편, 잡종으로 추정되는 논산 개체군의 flavonoid 조성은 F. japonica var. japonica, F. forbesii 및 F. sachalinensis와 일부 compound를 공유하는 것으로 나타났다. Fallopia japonica var. japonica의 경우, 염색체수 배수화에 따른 flavonoid 조성의 정성적 차이는 발견할 수 없었으나, 지리적 변이가 일부 나타나는 것으로 밝혀졌다.

• 한국환경생태학회지
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• 제18권2호
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• pp.221-230
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• 2004

본 연구결과 독도의 식물종은 총 1문 3강 21목 29과 50속 48종 1아종 9변종 1품종으로 총 59종류가 생육하는 것으로 밝혀졌다. 동도의 경우 유채와 소리쟁이 등의 귀화식물이 넓은 면적에 분포하고 있으며. 독도 식생으로 보이는 갯제비쑥, 돌피, 땅채송화, 섬갯장대, 섬기린초 등이 피해를 받고 있다. 서도의 경우 등산로가 풍화작용으로 많이 훼손되어 상당히 위험하며, 섬정상부에서 북서쪽 아래로 왕호장근이 군락을 이루고 있다. 섬에 있는 나무로는 사철나무, 섬괴불나무 등이 있으며, 식재된 수종으로 해송과 무궁화가 현재 생육하고 있다. 독도에서 조사된 특정식물종은 참나리, 갯까치수영, 왕호장근 3종이며, 그 중 정밀생태종은 왕호장근 한 종으로 조사되었다. 독도는 귀화식물, 무분별한 건물의 건립과 조림사업으로 인하여 많이 훼손이 되었으며, 이에 대한 복원방안이 필요하다. 이를 위해서는 장, 단기적인 식생복원계획과 학제간의 연구. 지역단체의 관심이 필요하다.

• 생약학회지
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• 제39권3호
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• pp.223-227
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• 2008

Advanced glycation end products (AGEs) contribute to the progression of micro and macrovsacular complication of diabetes and therefore present a promising target for therapeutic agents. In this study, 40 Korean herbal medicines have been investigated with an in vitro evaluation system using AGEs inhibitory activity. Of these, 21 herbal medicines $(IC_{50}<50{\mu}g/ml)$ exhibited an inhibitory activity against AGEs formation compared with anminoguanidine $(IC_{50}=72.12{\mu}g/ml)$. Particularly, 7 herbal medicines, Actinidia arguta (root and stem), Crataegus pinnatifida (twig), Camellia japonica (whole), Kalopanax pictus (bark), Lagerstroemia indica (leaf-stem), Reynoutria sachalinensis (root) showed more potent inhibitory activity (approximately 3-10 fold) than the positive control aminoguanidine.

• 한국조경학회지
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• 제25권4호
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• pp.123-140
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• 1998

The flora of Kunsan Wolmyong park was 77 families, 168 genera, 240 species, 2 subspecies, 35 varieties, 1 formae or 278taxa. Using the Phytosociology method, 12 plant communities were recognized ; Alnus japonica, Pinus densiflora, Pinus thunbergii, Pinus rigida, Castanea crenata, Quercus acutissima, Robinia pseudo-acacia, Alnus hirsuta, Quercus serrata, Aluns firma, Liriope platyphylla and Reynoutria communities. Similarity between different communities was low for most of the cases except for Pinus densiflora, Pinus Thunbergii and Pinus rigida communities kept comparely high with ond another. Species diversity was analyzed by species richness(SR), species diversity index(H') and evenness(J'). Castanea crenata, Robinia pseudo-acacia and Alnus firma communities were higher in SR, H' than the other communities. But Pinus rigida, Quercus acutissima and castanea crenata communities were higher in evenness than the other communities. To investigate the plant community structure and to establish restoration counter plan of a Wolmyeng Park in Kunsan City. As a remedial approach, following is propesed. first, Establishment of an adequate planting plan and development of slope stalilization method by planting native species. second, Sellection of adequate species by planting experiments for pioneer species, native species, and dietary species. third, Landscape planting zones should be managed artificially, the others be managed with ecological approach.

• 생약학회지
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• 제34권1호통권132호
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• pp.109-117
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• 2003

Arachidonic acid(AA), which is stored in membrane glycerophospholipids, is liberated by phospholipase $A_2(PLA_2)$ enzymes and is sequentially converted to cyclooxygenase (COX) and lipoxygenase (LOX) then to various bioactive prostaglandins (PGs,) and leukotrienes (LTs). In order to find the specific inhibitors of AA metabolism enzymes such as $PLA_2$, COX-2, 5-LO and lyso PAF acetyltransferase. 195 Korean indigenous plant extracts were evaluated for their inhibitory activity on $PGD_2,\;LTC_4$ production from cytokine-induced mouse bone marrow-derived mast cells (BMMC) and arachidonic acid released from phospholipid and PAF production from lyso PAF. From this screening procedure, methanol extract of eight plants such as Saururus chinensis, Aster tataricus, Chrysanthemum cinerariaefolium, Reynoutria japonica, Disocorea nipponica, Epimedium koreanum, impatiens textori, Veronica rotunda var. subintegra were found to inhibit production of inflammatory mediators in vitro assay system.

• 동의생리병리학회지
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• 제30권1호
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• pp.40-46
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• 2016

Many medicinal plants have been used for the treatment of edema, jaundice, and gonorrhea in traditional Oriental medicine. This screening study was designed to search the positive inotropic effects of herbal extracts in beating rabbit atria. Aquarius extracts of twenty six herbs were examined in atrial mechanical dynamics such as pulse pressure and stroke volume and atrial natriuretic peptide (ANP), one of the main hormones involved in the regulation of the body fluid and blood pressure homeostasis in perfused beating rabbit atria. Sophora flavescens Ait., Rheum officinale Baill., Acorus gramineus Sol., Chelidonium majus L., Pulsatilla koreana Nakai., Reynoutria japonica Houtt., Euphorbia lathyris L., Pyrrosia lingua (Thunb.) Farwell, Poncirus trifoliata Rafin., Anemarrhena asphodeloides Bunge, Kochia scoparia Schrad. significantly increased stroke volume and pulse pressure. However, those herbal extracts were not induced ANP secretion. We clarified the eleven herbal extracts for the positive inotropic effect independent of ANP secretion in beating rabbit atria. Thus these results provide a beneficial data for the treatment of the impairment of body fluid and blood pressure in traditional Oriental medicine.