• BMB Reports
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• v.53 no.4
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• pp.191-205
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• 2020

The unexpected pandemic set off by the novel coronavirus 2019 (COVID-19) has caused severe panic among people worldwide. COVID-19 has created havoc, and scientists and physicians are urged to test the efficiency and safety of drugs used to treat this disease. In such a pandemic situation, various steps have been taken by the government to control and prevent the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2). This pandemic situation has forced scientists to rework strategies to combat infectious diseases through drugs, treatment, and control measures. COVID-19 treatment requires both limiting viral multiplication and neutralizing tissue damage induced by an inappropriate immune reaction. Currently, various diagnostic kits to test for COVID-19 are available, and repurposing therapeutics for COVID-19 has shown to be clinically effective. As the global demand for diagnostics and therapeutics continues to rise, it is essential to rapidly develop various algorithms to successfully identify and contain the virus. This review discusses the updates on specimens/samples, recent efficient diagnostics, and therapeutic approaches to control the disease and repurposed drugs mainly focusing on chloroquine/hydroxychloroquine and convalescent plasma (CP). More research is required for further understanding of the influence of diagnostics and therapeutic approaches to develop vaccines and drugs for COVID-19.

• Journal of KIISE
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• v.45 no.3
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• pp.242-250
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• 2018

For high-quality software development, it is necessary to detect and fix the defects inserted. If defect management activities are not properly performed, it will lead to the project delay and project failure due to rework. Therefore, organizations need to establish defect management process and institutionalize it. Process standard models handle defect management in the area of project monitoring and control. However, small organizations experience difficulties in implementing and applying defect management process in a real situation. In this paper, we propose a defect management process for small organization which is designed in accordance with the characteristics of a small projects such as few participants and short development period. The proposed defect management process will be based on a tool chain with open source software such as Redmine, Subversion, Maven, Jenkins that support a defect management process and SW Visualization in systematic way. We also proposed a way of constructing defect database and various methods of analyzing and controlling defect data based on it. In an effort to prove the effectiveness of the proposed process, we applied the process and tool chain to a small organization.

• Korean Journal of Construction Engineering and Management
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• v.16 no.2
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• pp.21-28
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• 2015

Construction defects are major components that result in cost overruns and schedule delays in construction projects. There have been extensive research efforts to investigate the cause of defects. However, little effort has been devoted to analyze correlation among various reasons of construction defects while a defect is not usually an outcome of a single cause, but rather occurs when several interrelated causes combine. Based on this recognition, this paper analyzes 831 nonconformity reports collected from 30 construction projects in Korea from 2011 to 2014. The correlation analysis revealed that a significant portion of construction defects occurred in the procurement and construction phase and as the pattern of function defect and installation defect. Triggered by human error, defective material and faulty method, these defects are treated by conccession, repair, rework that can significantly lower the cost and schedule performance. This paper is significant in terms of providing a theoretical basis for analyzing correlation among various reasons of construction defects and quantitative measures for establishing effective defect prevention strategies.

• Korean Journal of Construction Engineering and Management
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• v.9 no.5
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• pp.214-226
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• 2008

Construction delay caused considerable losses to project parties. Avoiding construction delays is important to save costs for project stakeholders. The main objective of this paper is to identify major causes of construction delays of apartment construction projects in Vietnam. Sixteen causes of delay were identified through a questionnaire survey of 166 professionals. Factor analysis was employed to categorize these causes. The results of the survey revealed the main causes of delay of apartment projects in Vietnam are: (1) owner's and contractor'S financial difficulties; (2) lack of experienced contractors; (3) late delivery of materials; (4) late construction site handover; (5) owner's late payments for completed works; (6) low bid prices; (7) inappropriate construction method; and (8) defective works and unnecessary reworks. Factor analysis uncovered that causes of delay can be grouped under five categories labeled the five INs: incompetence, ineffectiveness, inadequateness, inapplicableness and inconceivableness. Comparative analysis between the Vietnam construction industry (VCI) and the Korea construction industry (KCI) has been performed to infer valuable lessons for researchers and practitioners in the VCI and the KCI. Comparative analysis indicated that main causes of delay in the VCI somewhat differ from main causes of delay in the KCI. However, "contractor'S financial difficulties", "late construction site handover", "unnecessary rework", "incapable designers", "site clearance difficulties" are common causes of delay in the VCI as well as the KCI. The findings of this research can be used as a guideline to overcome problems in the VCI as well as in other construction industries. Since Korea has emerged as the first largest foreign investor in Vietnam, the results of this study may be useful not only to practitioners and researchers in Vietnam but also to participants in Korea.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.40 no.2
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• pp.145-149
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• 2017

One of the challenges facing precision manufacturers is the increasing feature complexity of tight tolerance parts. All engineering drawings must account for the size, form, orientation, and location of all features to ensure manufacturability, measurability, and design intent. Geometric controls per ASME Y14.5 are typically applied to specify dimensional tolerances on engineering drawings and define size, form, orientation, and location of features. Many engineering drawings lack the necessary geometric dimensioning and tolerancing to allow for timely and accurate inspection and verification. Plus-minus tolerancing is typically ambiguous and requires extra time by engineering, programming, machining, and inspection functions to debate and agree on a single conclusion. Complex geometry can result in long inspection and verification times and put even the most sophisticated measurement equipment and processes to the test. In addition, design, manufacturing and quality engineers are often frustrated by communication errors over these features. However, an approach called profile tolerancing offers optimal definition of design intent by explicitly defining uniform boundaries around the physical geometry. It is an efficient and effective method for measurement and quality control. There are several advantages for product designers who use position and profile tolerancing instead of linear dimensioning. When design intent is conveyed unambiguously, manufacturers don't have to field multiple question from suppliers as they design and build a process for manufacturing and inspection. Profile tolerancing, when it is applied correctly, provides manufacturing and inspection functions with unambiguously defined tolerancing. Those data are manufacturable and measurable. Customers can see cost and lead time reductions with parts that consistently meet the design intent. Components can function properly-eliminating costly rework, redesign, and missed market opportunities. However a supplier that is poised to embrace profile tolerancing will no doubt run into resistance from those who would prefer the way things have always been done. It is not just internal naysayers, but also suppliers that might fight the change. In addition, the investment for suppliers can be steep in terms of training, equipment, and software.

• Journal of IKEEE
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• v.20 no.3
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• pp.310-313
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• 2016

In this paper, we propose the tester apparatus for 48 channel GM Tube sensor. The proposed apparatus can test up to 48 channel GM tube simultaneously to detect the defect and analyze the sensor characteristic. 300-1000V variable high voltage generation circuit is utilized for the apparatus suitable for the sensor characteristic. Thus, the proposed system is useful for various GM Tube sensor characteristic analysis. Multiple sensor testing environment is established for the early detection of the defect and the analysis to reduce the costs for manufacturing and rework. Developed 48 channel GM Tube sensor test is evaluated with certified testing equipment and shows excellent performance with respect to the uncertainty of the sensor test results.

• Korean Journal of Construction Engineering and Management
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• v.15 no.2
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• pp.122-131
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• 2014

As plant market grows up, client demands to increase quality, technology and to reduce construction period. Due to the vast scale of the construction site and complexity of process, plant project can have some problems of communication among the project participants, the duplication of work, errors and rework. As a result those cause more costs, delay the construction schedule and reduce productivity and quality. Therefore, real-time communication between participants and real-time sharing of information such as material, equipment and construction are required in plant project site. This research aims to propose process and develop system using NFC(Near Field Communication) technology and augmented reality technology with mobile device for plant construction site. Administrators and operators are able to work efficiently using proposed process and system which create an environment designed to share and deliver information such as material, construction information.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.8
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• pp.1761-1768
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• 2013

Digital shipbuilding is a technology to reduce the total cost and lead time inevitably made by reschedule and rework in a shipyard. Strategic planning should be undertaken in order to have an effect on the applicable field. We aim at planning a strategy of digital shipbuilding technology by analysis of production planning workflow in this paper. In the basis of BPR methodology, the as-is business process is analyzed to build an workflow model, and derive the bottleneck business process. We dig into the inside details of the process to illustrate an diagram of the core improvement opportunities, and perform process simulation not only to create the application scenarios but also to expect the main effects. The application strategy will make a basic sketch to save both the production cost and time for high quality products in the shipyards.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.10
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• pp.236-242
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• 2019

Recently, scanning projects have been carried out in various construction and construction fields for maintenance purposes. The point cloud generated by the scan results is composed of a number of points representing the object to be scanned. The process of extracting the necessary information, including dimensions, from such scan data is called paradox. The reverse engineering process of modeling a point cloud as BIM involves considerable manual work. Owing to the time-consuming reverse engineering nature of the work, the costs increase exponentially when rework requests are made, such as design changes. Reverse engineering automation technology can help improve these problems. On the other hand, the reverse design product is variable depending on the use, and the kind and detail level of the product may be different. This paper proposes the G2BM (Geometry-to-BIM mapping) rule definition method that automatically maps a BIM object from a primitive geometry to a BIM object. G2BM proposes a process definition and a customization method for reverse engineering BIM objects that consider the use case variability.

• Journal of Korean Academy of Nursing Administration
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• v.1 no.2
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• pp.388-407
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• 1995

This study is (a) to describe the history of Total Quality Management (TQM) generated in the industry, health care service, and nursing society ; (b) to define the concept, total quality management including the definition of quality ; (C) to explain the each principle of TQM theory developed by main theorists, E. Deming, J. Juran, and B. Crosby ; (d) to give the examples related to TQM implementation at the health care organization ; and (e) to mention the extent to which the health care organizations are able to evaluate their cultural organization toward TQM and have had the way to measure the effect of TQM implementation. TQM referred to Continuous Quality Improvement(CQI), Quality Improvement(QI), and Total Quality Improvement(TQI), was not recognized by experts in the United States industry, but by economists in Japan until the end of the 1970's. However, the United States' government led to introduce the principles of TQM to general industry as well as health care service area so that TQM became a main philosophy to manage the organizations in health care service. TQM is a structured, systematic process for creating organization-wide participation in planning and implementing continuous improvement in quality. E. Deming established the "Chain reaction in Quality" and the fourteen point of TQM. The Chain reaction in quality is to describe the relationship among the reduction of waste, rework, and delay, quality improvement, customer satisfaction, and productivity. There are fourteen points to explain the principles of TQM by E. Deming. Juran defined the "Quality Trilogy" to improve the level of quality in any organization. Quality Trilogy has three steps such as quality planning, quality control, and quality improvement for implementing the TQM projects. Crosby describes his TQM theory by establishing "Four Absolutes" and "Fourteen steps in TQM" implementation. Until now, most healthcare organizations have made efforts to organize the TQM task team and to implement TQM principles with various issues. There are three priorities to select the TQM issues : High-volume, High-risk, and Problem-prone. However, there is no absolute, credible measurement yet to evaluate the effects of TQM implementation in health care organization regardless of the classification of health care organizations, geographical background, and social influence. Thus, developing the evaluation way in terms of TQM is the foremost task in health service area. The most important thing for TQM implementation in the organization is to settle up the concept, cultural transformation from traditional management toward quality.