• 정신신체의학
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• 제12권2호
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• pp.135-144
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• 2004

연구목적 : 본 연구의 목적은 기공에 기초한 스트레스 관리 프로그램이 산모의 우울, 불안 등의 정서에 미치는 영향에 대하여 알아보고자 하였다. 방법: 임신 16주 이상의 산모들을 대상으로 하였다. 기공프로그램군은 8주동안, 일주일에 2번씩 기공프로그램에 참여한 52명으로 구성되었으며, 교육군은 8주동안 1주일에 1번씩 산모교육에 참여한 40명으로 구성되었다. 평가도구는 우울 수준을 측정하는 척도로서 해밀턴 우울 척도(Hamilton depression rating scale, HAMD), 벡 우울 척도(Beck depression inventory, BDI), 에딘버러 산후 우울증 척도(Edinburgh postnatal depression scale, EPDS)를 이용하였다. 불안 수준을 측정하는 척도로서 스필버거 특성 상태 불안척도-1 (Spielberger trait state anxiety inventory-1, STAI-1), 해밀턴 불안 척도(Hamilton anxiety scale, HAM-A)를 이용하였다. 기공과 교육 프로그램 시작전, 이후 2주, 4주, 8주에 걸쳐 산모의 우울, 불안 수준을 상기 척도로 측정하였다. 결과: 기공프로그램군은 프로그램 시작 전과 8주 후를 비교하였을 때 유의미하게 불안과 우울 수준이 모든 척도에서 호전되었다. 반면 교육군은 시작 전과 8주 후를 비교하였을 때 유의미한 호전은 없었다. 두 집단의 프로그램 전후 변화량을 비교한 결과 기공프로그램군이 교육군에 비하여 통계적으로 유의미한 변화를 보였다. 결론: 본 연구는 기공에 기초한 스트레스 관리 프로그램이 산모의 불안과 우울감을 조절하는데 효과적인 방법일 수 있음을 시사한다.

• 가정과삶의질연구
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• 제34권6호
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• pp.55-67
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• 2016

The purpose of this study was to examine the relationship between Toddlers'negative emotionality and mothers' parenting stress and the moderating roles of a husbands'cooperation, mother-teacher partnership, and other social support. The participants of this study were 248 mothers with toddlers aged 24-35 months. The method of research used was the questionnaire method. The collected data were mainly analyzed by descriptive statistics, t-test, one-way ANOVA, $Scheff{\acute{e}}$ test, Pearson's correlation and multiple regression analysis. The main results of this study were as follows. First, there were differences in mother's parenting stress according to individual characteristics such as mothers employment status, parenting costs, mother's feeling of pregnancy. Second, a moderator effect of a husbands' cooperation was found in the relationship between toddlers'negative emotionality and mothers' parenting stress. Therefore, it was confirmed that husband's cooperation is more of an important factor in nursing children with negative emotions than other support systems.

• 대한의생명과학회지
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• 제21권1호
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• pp.15-22
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• 2015

Dexamethasone, a synthetic glucocorticoid (GC), is clinically administered to woman at risk for premature labor to induce fetal lung maturation. However, exposure to repeated or excess GCs leads to intrauterine growth restriction (IUGR) and subsequently increases risk of psychiatric and cardio-metabolic diseases in later life through fetal programming mechanisms. GCs are key mediators of stress responses, therefore, maternal nutrient restriction or psychological stress during pregnancy also causes negative impacts on birth and neurodevelopment outcome of fetuses, and other congenital defects, such as craniofacial and skeletal abnormalities. In this study, to examine the effect of prenatal stress on fetal skeletal development, dexamethasone (1 mg/kg [DEX1] or 10 mg/kg [DEX10] maternal body weight per day) was administered intraperitoneally at gestational day 7.5~9.5 and the skeletons were prepared from embryos at day 18.5. Seven out of eighteen (39%) embryos treated with DEX10 showed axial skeletal abnormalities in either the T13 or L1 vertebrae. In addition, examination of the sternum revealed that xiphoid process, the protrusive triangular part of the lower end of the sternum, was bent more outward or inward in DEX group embryos. In conclusion, our findings suggest a possible link to the understanding of the effect of uterine environment to the fetal skeletal features.

• 한국보건간호학회지
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• 제35권1호
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• pp.120-134
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• 2021

Purpose: The reproductive health of women in early adulthood can affect pregnancy, childbirth, and menopause in later life. Menstrual symptoms not only affect daily life, but are also a reflection of a woman's reproductive health. This study was conducted to explore the factors affecting menstrual symptoms among university students. Methods: The general characteristics, life style, menstrual characteristics, stress, and menstrual symptom of 177 female students were assessed through an online survey at one university. An independent sample t-test, one-way variance analysis, correlation analysis, and multiple regression analysis were performed using the SPSS 22.0 program. Results: The menstrual symptom score was 91.68±32.11 points, and the score of 'mood change' was the highest. Stress (��=.38, p<.001), amount of menstruation (��=.20, p=.001), menarche age (��=-.18, p=.003), health problems (��=.16, p=.010), and age (��=.15, p=.016) were found to have a significant effect on menstrual symptom, and the explanatory power of the regression model was 40%. Conclusion: This study investigated the degree and influencing factors of menstrual symptom using the Korean Menstrual Symptom Scale (KMSS) developed for Korean university students. Among the factors influencing menstrual symptom, stress appeared to play a significant role. Stress management, observation of menstrual characteristics, and general health care are necessary to maintain a woman's reproductive health.

• 대한한방부인과학회지
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• 제18권4호
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• pp.165-182
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• 2005

Purpose : To investigate the stress degree of infertile women and its correlations with Qi-stasis. Methods : 162 women, enrolled for treatment at oriental hospital, completed Infertility Stress Scale, Stress Response Inventory and Qi-stasis questionnaire. Their demographic features and infertility-related factors were recorded. 137 infertile women and 25 normal subjects were analyzed. Results : 1. 43 infertile women(33.86%) among the sample group were diagnosed as Qi-stasis. 2. There were close score correlations among Infertility Stress Scale, Stress Response Inventory, and Qi-stasis(p=.000). 3. Experience of Assisted Reproductive Technology (ART), possibility of spontaneous pregnancy, coitus frequency, whether the spouse is the eldest son or not had the influences on Infertility Stress. Abortion experience had influences on stress response and Qi-stasis. 4. It was revealed that Infertile women(n=137) had significantly higher scores of 'Infertility Stress' and subscales such as 'sexual satisfaction', 'marital satisfaction', 'familial adjustment', 'social adjustment' as well than control group(n=25). Conclusion : The results provide that the stress degree of infertile women had significant correlations with Qi-stasis and show the possibilities of oriental medicine treatment for stresses of infertile women.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 2004년도 제56차 추계 학술대회 연제집
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• pp.38.2-38.2
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• 2004

• 여성건강간호학회지
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• 제20권2호
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• pp.163-172
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• 2014

Purpose: The purpose of this study was to determine the stress, depression, and fetal attachment of pregnant women who underwent infertility treatment, and to identify factors associated with fetal attachment. Methods: As a correlation survey design, data were collected from 136 pregnant women who underwent infertility treatment. Data were analyzed using ${\chi}^2$-test, t-test, ANOVA, Pearson correlation coefficients, and stepwise multiple regression. Results: Stress, depression, and fetal attachment averaged $3.01{\pm}0.60$ (range of scale 1~5), $10.02{\pm}6.51$ (out of a possible 63), and $3.64{\pm}0.55$ (range of scale 1~5), respectively. Level of fetal attachment was higher when mother's age was less than 35, having other children, and having prenatal education experience. Lower score of depression and client's age less than 35 were significant factors affecting fetal attachment. Conclusion: Infertility is a life-affecting trauma for the individual, and personal and social changes due to infertility cause physical and psychological difficulties even after a successful pregnancy with infertility treatment. Therefore, prenatal management programs need to be developed giving consideration to the emotional and physical changes in order to promote physical and psychological stability in the women pregnant following infertility treatment.

• Asian-Australasian Journal of Animal Sciences
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• 제24권4호
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• pp.479-484
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• 2011

The study was conducted on 20 Holstein X Sahiwal cross bred dairy cows, with an average milk production of $2,752{\pm}113.79$ liters in $284{\pm}5.75$ days during a single lactation, that were divided in to two groups of 10 animals. We investigated the oxidative stress and antioxidant status during the transition period in dairy cows. In this study, plasma level of MDA was considered as an indicator of lipid peroxidation and SOD, catalase, GSH and GSHPx as antioxidants. The lipid peroxidation was significantly (p<0.001) higher in cows during early lactation as compared to the cows in advanced pregnancy. A significant positive correlation (r = +0.831, p<0.01) was determined between MDA and catalase in early lactating cows. In early lactating cows, blood glutathione was significantly lower than in advanced pregnant cows. However, early lactating cows showed non-significant negative correlation for all antioxidant enzymes with lipid peroxidation. In conclusion, dairy cows seemed to have more oxidative stress and low antioxidant defense during early lactation or just after parturition than advanced pregnant cows, and this appears to be the reason for their increased susceptibility to production diseases (e.g. mastitis, metritis, retention of fetal membranes etc.) and other health problems.

• 대한간호학회지
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• 제34권5호
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• pp.722-728
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• 2004

Purpose: This study was designed to determine the predictors of postpartum depression. Method: One hundred-sixty one women within one year after delivery from one public health center located in the northern area of Seoul were used in this study. The instruments were a survey of general characteristics, the Edinburgh Postnatal Depression Scale, recent life events index, perceived social support from family, Quality of marriage index, parenting stress index, and Rosenberg's self-esteem inventory. Data was analysed using descriptive statistics, Pearson correlation coefficients, and logistic regression. Result: The average item score of the EPDS was 6.67. 12.4% of respondents, who scored above a threshold 12, were likely to be suffering from a depression of varying severity. The fitness of the model for explaining postpartum depression from six variables, plan for pregnancy, family support, quality of marital relation, perceived social support, life events, childcare stress, and self-esteem, was statistically significant and the predictive power of these variables was 90.9%. The significant predictors of postpartum depression were family support and child care stress. Conclusion: Further research is needed to identify the prevalence rate of postpartum depression using more reliable sampling methods from a large general population. Nursing interventions need to be developed for promoting family support and reducing childcare stress.

• The Korean Journal of Physiology and Pharmacology
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• 제11권3호
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• pp.129-133
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• 2007

There are growing evidences suggesting a pivotal role of oxidative stress in the pathophysiology of preeclampsia. We investigated oxidative stress in the rat model of preeclampsia, and in clinical cases. Pregnant female rats were injected intraperitoneally with deoxycorticosterone acetate (DOCA) and given 0.9% saline as drinking water during their pregnancy. We assessed plasma $F_2-isoprostane(8-iso-PGF_{2{\alpha})$ and malondialdehyde (MDA) in a rat model, and the same markers in the plasma of maternal blood and fetal cord blood in pregnant women with preclampsia. Blood samples from the umbilical arteries and veins were collected separately. The concentrations of MDA were increased in the preeclampsia groups of animal and humans, compared with the control group; it was significantly increased in the umbilical artery and vein of the preeclampsia group. The concentrations of $F_2-isoprostane$ were elevated in the preeclampsia groups of animal and humans, compared with the control group, and the increase in $F_2-isoprostane$ concentration was prominent in the umbilical vein than umbilical artery of the preeclampsia group. Therefore, it appears that the placenta has an important role in the pathophysiology of preeclampsia, and the $F_2-isoprostane$ of the umbilical vein may serve as a relatively reliable marker for ischemic/hypoxic injury to the fetus during the perinatal period.