• The Transactions of the Korea Information Processing Society
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• v.2 no.4
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• pp.554-560
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• 1995

In this paper, we suggest a parallel algorithm to merge priority queues organized in two heaps, kheap and nheap of sizes k and n, correspondingly. Employing max(2$^{-1}$, $\ulcorner$(m＋1)/4$\lrcorner$'s processors, this algorithm requires O(log(n/k)＊log(n)) on an EREW-PRAM, where i is the height of the heap and m is the summation of sizes n and k. Also, when we run it on the MasPar machine, this method achieves a 33.934-fold speedup with 64 processors to merge 8 million data items which consist of two heaps of different sizes. So our parallel algorithm's EPU is close to 1, which is considered as an optimal speedup ratio.eedup ratio.

• BMB Reports
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• v.47 no.8
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• pp.424-432
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• 2014

The defining feature of Parkinson's disease is a progressive and selective demise of dopaminergic neurons. A recent report on Parkinson's disease animal model demonstrates that poly (ADP-ribose) (PAR) dependent cell death, also named parthanatos, is accountable for selective dopaminergic neuronal loss. Parthanatos is a programmed necrotic cell death, characterized by PARP1 activation, apoptosis inducing factor (AIF) nuclear translocation, and large scale DNA fragmentation. Besides cell death regulation via interaction with AIF, PAR molecule mediates diverse cellular processes including genomic stability, cell division, transcription, epigenetic regulation, and stress granule formation. In this review, we will discuss the roles of PARP1 activation and PAR molecules in the pathological processes of Parkinson's disease. Potential interaction between PAR molecule and Parkinson's disease protein interactome are briefly introduced. Finally, we suggest promising points of therapeutic intervention in the pathological PAR signaling cascade to halt progression in Parkinson's disease.

• Journal of Microbiology
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• v.40 no.1
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• pp.63-69
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• 2002

A total of twenty-five norfloxacin resistant Escherichia coli were isolated from Joongrang-chun stream, a branch of the Han River in Seoul, Korea from May to July in 2000 and their norfloxacin resistance mechanism was characterized for target site mutation, permeability, and efflux pump. Fourteen iso- lates contained the same three mutations, Ser83→Leu and Asp87→Asn in GyrA and Ser90→ lle in ParC. Six isolates had Ser83→Leu and Asp87→Tyr in GyrA and Ser87→lle in ParC while one isolate had Ser83→Leu and Va1103→Ala in GyrA and Ser80→lle in ParC. Two isolates had mutation(s) in GyrA without any mutation in ParC. Two isolates had Ser80→Arg in ParC instead of the commonly found Ser80→lle. Every norfloxacin resistant isolate had an efflux system but the correlation between the efflux activity and MIC was not observed. The amount of OmpF for norfloxacin permeability decreased in resistant isolates compared to the susceptible strains. When amplified polymorphic DNA (RAPD) and pulse field gel electrophoresis (PFGE) were performed, these isolates showed no similarity to each other or clinical isolates.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7451-7457
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• 2013

Background: Understanding and enhancing change capabilities, including Practice Adaptive Reserve (PAR), of Community Health Centers (CHCs) may mitigate cancer-related health disparities. Materials and Methods: Using stratified random sampling, we recruited 232 staff from seven CHCs serving Asian Pacific Islander communities to complete a self-administered survey. We performed multilevel regression analyses to examine PAR composite scores by CHC, position type, and number of years worked at their clinic. Results: The mean PAR score was 0.7 (s.d. 0.14). Higher scores were associated with a greater perceived likelihood that clinic staff would participate in an evidence-based intervention (EBI). Constructs such as communication, clinic flow, sensemaking, change valence, and resource availability were positively associated with EBI implementation or trended toward significance. Conclusions: PAR scores are positively associated with perceived likelihood of clinic staff participation in cancer screening EBI. Future research is needed to determine PAR levels most conducive to implementing change and to developing interventions that enhance Adaptive Reserve.

• BMB Reports
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• v.46 no.11
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• pp.544-549
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• 2013

High mobility group box 1 (HMGB1) is involved in the pathogenesis of vascular diseases. Unlike activated protein C (APC), the activation of PAR-1 by thrombin is known to elicit proinflammatory responses. To determine whether the occupancy of EPCR by the Gla-domain of APC is responsible for the PAR-1-dependent antiinflammatory activity of the protease, we pretreated HUVECs with the PC zymogen and then activated PAR-1 with thrombin. It was found that thrombin downregulates the HMGB1-mediated induction of both TNF-${\alpha}$ and IL-6 and inhibits the activation of both p38 MAPK and NF-${\kappa}B$ in HUVECs pretreated with PC. Furthermore, thrombin inhibited HMGB1-mediated hyperpermeability and leukocyte adhesion/migration by inhibiting the expression of cell adhesion molecules in HUVECs if EPCR was occupied. Collectively, these results suggest the concept that thrombin can initiate proinflammatory responses in vascular endothelial cells through the activation of PAR-1 may not hold true for normal vessels expressing EPCR under in vivo conditions.

• Nuclear Engineering and Technology
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• v.54 no.11
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• pp.4159-4169
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• 2022

Hydrogen mitigation using Passive Autocatalytic Recombiners (PARs) has been widely accepted methodology inside reactor containment of accident struck Nuclear Power Plants. They reduce hydrogen concentration inside reactor containment by recombining it with oxygen from containment air on catalyst surfaces at ambient temperatures. Exothermic heat of reaction drives the product steam upwards, establishing natural convection around PAR, thus invoking homogenisation inside containment. CFD models resolving individual catalyst plate channels of PAR provide good insight about temperature and hydrogen recombination. But very thin catalyst plates compared to large dimensions of the enclosures involved result in intensive calculations. Hence, empirical correlations specific to PARs being modelled are often used in integral containment studies. In this work, an experimentally validated CFD model of PAR has been employed for developing an empirical correlation for Indian PAR. For this purpose, detailed parametric study involving different gas mixture variables at PAR inlet has been performed. For each case, respective values of gas mixture variables at recombiner outlet have been tabulated. The obtained data matrix has then been processed using regression analysis to obtain a set of correlations between inlet and outlet variables. The empirical correlation thus developed, can be easily plugged into commercially available CFD software.

• Journal of Families and Better Life
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• v.9 no.2
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• pp.241-251
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• 1991

The Purpose of this study was the development of scale to measure the Perceived Adequacy of Resources(PAR). A 38-item instrument was analysed with responses form 300 wives dwelling in Seoul. PAR was categorized housing, health, time money, interpersonal, knowledge/skills, community resources, Data were analysed by the method of Pearson's Correlation, Factor Analysis and Multiple Regression. Items were loaded eight resource categories such as time housing, money , health, knowledge, social support, community, psychological relationship. Internal consistency of the scale was high(Cronbach's α=.85) The result proposed PAR constructed 28 items.

• Proceedings of the Korean Society of Agricultural Engineers Conference
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• 1999.10c
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• pp.434-438
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• 1999

It was neede to know the amount of PAR to predict the growth of crops, and the quantity of total radiation to control the temperature by shading screen in the greenhouse. Experiments have been conducted to determine the correlation between the hourly PAR and total solar radiation the transmisson of PAR and total solar radiaiton oat canopy location, and the relationship between the illuminaance and total solar radiation. Additional experiments are needed to confirm thses experimental results.

• Proceedings of the Korea Information Processing Society Conference
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• 2011.11a
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• pp.1207-1210
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• 2011

본 논문에서는 PAR-트리라는 공간색인구조를 제안한다. PAR-트리는 object distribution heuristic(객체분할법)으로 absolute crowd index(절대 복잡도)를 사용하여 공간 데이터 객체를 여러 개의 데이터 공간에 균일하게 배치함으로써 질의처리 속도를 향상시킨다. PAR-트리는 MXR-트리에 비해 높은 공간활용도와 빠른 질의 반응시간을 보임으로써 다차원 데이터베이스를 위한 효율적인 색인구조로 사용이 될 것으로 기대된다.

• Journal of architectural history
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• v.5 no.1 s.9
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• pp.113-122
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• 1996

Cette etude vise a reveler une verite du Nouveau Brutalisme des Smithson (Alison et Peter). Nous examinerons donc d'abord l'universalitf de leur oeuvre representatif, Ecole Secondaire de Hunstanton(projet, 1949; concours, 1950; construction, 1951-1954) et projet de Maison Soho a Londres(1952) comme un mouvement architectural. Et apres nous trouverons la faussete de leur but, realisation de l'ethique architecturale, sur ce mouvement en comparant les oeuvres des Smithson avec les deux constructions considerees souvent comme la categorie du Nouveau Brutalisme, la Calorie d'Art de l'Universite Yale(1951-1953) realisee par Louis I. Kahn(1901-1974) et le Centre Cuturelle de Georges-Pompodou(1971-1977) par Renzo Piano et Richard Rogers. En resultat, l'etique de Nouveau Brutalisme soutenue par les Smithson et defendue par Reyner Banham etait seulement pour cacher low limite architecturale et sa faiblesse. Ce mouvement etait aussi un mouvement personel plutot que general. On ne pourrait pas donc considerer les Smithson comme nouveaux brutalistes.