• Journal of the Korean Chemical Society
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• v.46 no.1
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• pp.46-51
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• 2002

The recognition and cleavage of 5S rRNA from P. alcaligenes by metallopeptides to the form $Ni(II){\cdot}Gly$-Gly-His(Arg)COOH and $Cu(II){\cdot}Gly$-Gly-His(Arg)COOH were investigated. The results of RNA cleavage analyses suggest that metallopeptides selectively target the unpaired or unstably paired bases of stem-loop structure of 5S rRNA. The selectivity of metallopeptides was little affected by the species of metal ion, Ni(II) or Cu(II). When the result of cleavage by metallopeptides was compared with that of by metal complexes M(II)CR, the recognition by metallopeptides was more selective and structure specific. The cleavage data by metallopeptides and other metal complexes were used to probe the secondary structure of 5S rRNA from P. alcaligenes.

• Women's Health Nursing
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• v.6 no.4
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• pp.566-578
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• 2000

This study was conducted to ascertain infant's sleep and feeding patterns for the purpose of building up the positive parent-child relationship and setting up a preliminary parenting education program. The subjects were 16 infants who were cared for in their houses. The data was collected using NCASA developed by Barnard et al. from October 1st to December 3lth, 1999. The analysis of data was done with SPSSWIN for descriptive statistics and t-test, ANOVA, Correlation Analysis. The result were as follows: 1. The average day sleep of the infant was 9.51 hours, night sleep was 6.27 hours, and total sleep was 15.84 hours. The longest period of day sleep was 3.02 hours, and the longest period of night sleep was 3.72 hours. The regularity of day sleep was 34.78%, night sleep was 61.72% and total was 43.76%. 2. The frequency of daytime feeding was 5.13 times, nighttime was 2.44 times and total was 7.38 times. The regularity of feeding was 52.14%. 3. In the correlation between sleep and feeding patterns, night sleep was negatively correlated with feeding method(r=-.52, P<0.05), the longest period of day sleep was negatively correlated with feeding method(r=-.73, P<0.001), feeding frequency(r=-.60, P<0.05), the regularity of feeding(r=-.70, P<0.001). The longest period of night sleep was negatively correlated with feeding frequency (r=-.53, P<0.05). Feeding method was positively correlated with feeding frequency(r=.71, P<0.001), the regularity of feeding(r=.57, P<0.05). Day sleep was positively correlated with total sleep(r=.93, P<0.001), the regularity of total sleep was positively correlated with the longest period of day sleep(r=.54, P<0.05), total sleep(r=.65, P<0.001). The regularity of feeding was positively correlated with feeding method(r=.57, P<0.05), total feeding frequency(r=.50, P<0.05), the frequency of daytime feeding(r=.61, P<0.05). Feeding method was positively correlated with total feeding frequency(r=.71, P<0.001). In conclusion, the study showed that infants slept more in the nighttime than in the daytime, but after 3 months the pattern changed and showed that nighttime sleep was increased. Also the regularity of night sleep was increased with the infant's age. Total feeding frequency was decreased with the infant's age, and the regularity of feeding was increased in infants who slept shorter periods in the daytime than in the nighttime.

• Journal of Korean Academy of Nursing
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• v.36 no.6
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• pp.925-932
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• 2006

Purpose: The purpose of this study was to identify the relationship between depression, perceived stress, fatigue and anger in clinical nurses. Method: A descriptive survey was conducted using a convenient sample. Data was collected by questionnaires from four hundred clinical nurses who worked at a university hospital. Radloff's CES-D for depression, Cohen, Kamarck & Mermelstein's Perceived Stress Scale, VAS for Fatigue, and Spielberger's STAXI for anger were used. The data was analyzed using the pearson correlation coefficient, students' t-test, ANOVA, and stepwise multiple regression with SPSS/WIN 12.0. Result: The depression of clinical nurses showed a significantly positive correlation to perceived stress(r=.360, p=.000), mental fatigue(r=.471, p=.000), physical fatigue(r=.350, p=.000), trait anger(r=.370, p=.000), anger-in expression(r=.231, p=.000), and anger-control expression(r=.120, p=.016). There was a negative correlation between depression and age(r=-.146, p=.003). The mean score of depression of nurses, 26, was a very high score and 40.8% of clinical nurses were included in a depression group. The main significant predictors influencing depression of clinical nurses were mental fatigue, trail anger, perceived stress, anger-in expression, and state anger, which explained about 32.7%. Conclusion: These results indicate that clinical nurses with a high degree of perceived stress, mental fatigue and anger-in expression are likely to be depressed.

• Journal of the Korean Applied Science and Technology
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• v.39 no.6
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• pp.839-852
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• 2022

This study is a descriptive research study to identify work stress, resilience, nursing performance and influencing factors so that nurses in small and medium-sized hospitals can flexibly cope with rapidly changing medical environments. The subjects of the study were 219 nurses working at four small and medium-sized hospitals located in S region, and the survey was conducted using a structured questionnaire. The collected data were analyzed by using descriptive statistics, t-test, ANOVA, Pearson's correlation analysis and multiple regression analysis. There was a negative correlation between work stress and nursing performance in small and medium-sized hospital nurses (r=-0.150, p<.05), and a positive correlation between work stress and resilience (r=0.160, p<.05). Nursing performance showed a positive correlation with resilience (r=0.351, p<.01). The variable affecting nursing performance was resilience (𝛽=.231, p<.01), and its explanatory power was 17.4% (Adj.R2=0.174, p<.001). Therefore, in order to improve the nursing performance of nurses, it is necessary to increase resilience.

• Bulletin of the Korean Mathematical Society
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• v.36 no.2
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• pp.287-303
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• 1999

The general solution of the functional equation f1(pr, qs) + f2(ps, qr) = g(p,q) + h(r,s) for p, q, r, s $\in$] 0, 1[will be investigated without any regularity assumptions on the unknown functions f1, f2, g, h:]0.1[->R.

• Journal of Microbiology and Biotechnology
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• v.31 no.8
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• pp.1098-1108
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• 2021

The literature indicates that LINC00174 promotes the growth of colorectal cancer (CRC) cells, but its research needs to be enriched. We tried to explore the function and mechanism of LINC00174 in CRC cell proliferation and migration. Bioinformatics analysis predicted the binding relationship and expressions of lncRNA, miRNA and mRNA. Clinical study analyzes the relationship between LINC00174 and clinical data characteristics of CRC patients. The expressions of LINC00174, miR-3127-5p and E2F7 were verified by RT-qPCR, and the combination of the two was verified by dual luciferase analysis and RNA immunoprecipitation as needed. Western blot was used to detect the expression of EMT-related protein and E2F7 protein. Functional experiments were used to evaluate the function of the target gene on CRC cells. LINC00174 was up-regulated in CRC clinical samples and cells and was related to the clinical characteristics of CRC patients. High-expression of LINC00174, contrary to the effect of siLINC00174, promoted cell viability, proliferation, migration and invasion, up-regulated the expressions of N-Cadherin, Vimentin, E2F7, and inhibited the expression of E-Cadherin. MiR-3127-5p was one of the targeted miRNAs of LINC00174 and was down-regulated in CRC samples. In addition, miR-3127-5p mimic partially reversed the malignant phenotype of CRC cells induced by LINC00174. Besides, E2F7 was a target gene of miR-3127-5p, and LINC00174 repressed miR-3127-5p to regulate E2F7. Our research reveals that LINC00174 affected the biological characteristics of CRC cells through regulated miR-3127-5p/ E2F7 axis.

• Proceedings of the Korean Society of Crop Science Conference
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• 1990.05a
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• pp.38-39
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• 1990

• Proceedings of the Korean Society of Crop Science Conference
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• 1990.05a
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• pp.64-65
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• 1990

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.4
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• pp.82-90
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• 2020

This study investigated the effects of empathy, self-control, and smartphone dependency on the interpersonal relationships of nursing students. The survey participants were 157 students in A city. The data was collected through self-report questionnaires that were obtained from May 27 2019 to May 31 2019. The data was analyzed using descriptive statistics and Independent t-tests, One-way ANOVA, Pearson correlation coefficients, and Stepwise multiple regression analysis of the SPSS 14.0 program. As a result, self-control (F=5.319, p=.006) and smartphone dependency (F=4.854, p=.009) showed significant differences according to the school records. Smartphone dependency (t=-3.381, p<.001) showed significant differences according to smartphone use. Age was found to have a statistically positive correlation with self-control (r=.194, p=.015) and it had a negative correlation with smartphone dependency (r=-.223, p=.005). Self-control was found to have a statistically positive correlation with empathy (r=.244, p<.01), interpersonal relationship (r=.540, p<.001). and negative correlation with smartphone dependency (r=-.432, p<.001). Empathy was found to have a statistically positive correlation with interpersonal relationships (r=.476, p<.001). Stepwise multiple regression analysis revealed that the predictors of interpersonal relationships were self-control (β=.477, p<.001), empathy (β=.359, p<.001), and smartphone use (β=.208, p<.01) which accounted for 45.0% of all the variance (F=12.029 p<.01). An enhancement program of nursing students' interpersonal relationships is needed that considers their self-control, empathy, and smartphone use.

• Journal of The Korean Society of Integrative Medicine
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• v.12 no.1
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• pp.73-81
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• 2024

Purpose : The purpose of this study was to identify the degree of occupational therapists' professional identity and examine the correlation between empowerment and burn out. We also investigated the effects of the occupational therapists' professional identity on empowerment and burn out. Through these assessments, we aimed to highlight the importance of professional identity and find methods to improve empowerment and reduce burn out in occupational therapists. Methods : The study was conducted from October 19 to from November 11, 2023. General characteristics, professional identity, empowerment, and burn out were examined using frequency analysis and descriptive statistics. The correlation between these factors was analyzed using Pearson's correlation coefficient. Multiple regression analysis was used to identify factors influencing empowerment and burn out. An α value =.05 was used to verify statistical significance. Results : First, Professional identity was an average 3.24±.37. Second, a significant correlation was found between professional identity and empowerment (r=.417, p<.01) and burn out (r=-.377, p<.01). As a result of the relationship between professional identity sub-factors and empowerment in professional organization (r=.270, p<.01),, belief in self-regulation (r=.258, p<.01), vocational consciousness (r=.348, p<.01), and belief in autonomy (r=.308, p<.01) showed a statistically significant correlation. Professional identity sub-factors were significantly correlated with burnout, professional organization (r=-.199, p<.05), belief in public service (r=-.153, p<.05), belief in self-regulation (r=-.334, p<.01), vocational consciousness (r=-.250, p<.01), and belief in autonomy (r=-.293, p<.01) showed a significant correlation. Third, professional identity sub-factors influencing empowerment were vocational consciousness (β=.154, p<.05) and belief in autonomy (β=.135, p<.05), and those influencing burnout were belief in self-regulation (β=-.389, p<.01) and belief in autonomy (β=-.244, p<.01). Conclusion : The study findings demonstrated that professional identity affects empowerment and burn out. Therefore, continuous study on the professional identity of occupational therapists is warranted.