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Studies on the Establishment of Cultural Fractice for $\underline{Angelica\;tenuissima}$ NAKAI II. Influence of Planting Density and Fertilizer Level on Growth and Root Yield of $\underline{Angelica\;tenuissima}$ NAKAI (고본(Angelica tenuissima Nakai)의 재배법 확립에 관한 연구 II. 재식밀도와 시비량이 고본의 생육 및 수량에 미치는 영향)

  • Choi E. O.;Seo J. S.;Jeong B. C.;Kang C. W.;Huh B. L.
    • Proceedings of the Korean Society of Crop Science Conference
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    • 1990.05a
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    • pp.118-119
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    • 1990
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Depressive Symptoms in Patients with Parkinson's Disease (파킨슨병 환자에서의 우울증상)

  • Lee, Moon-Sook;Yang, Chang-Kook;Hah, Hong-Moo;Kim, Jae-Woo
    • Korean Journal of Psychosomatic Medicine
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    • v.11 no.1
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    • pp.25-35
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    • 2003
  • Objectives: The aim of this study was to investigate 1) the prevalence of depressive symptoms, 2) the severity of depressive symptoms, 3) the correlation of depressive symptoms with clinical variables, and 4) factors that contribute to depressive symptoms in patients with Parkinson's disease. Methods: One hundred eighteen patients with Parkinson's disease referred from the Parkinson's Disease Clinic of Dong-A University Hospital, Busan, Korea, completed a self-administered questionnaire package, which included basic demographic data, the Beck Depression Inventory, the Parkinson's disease quality of life questionnaire, the Symptom Checklist-90-Revision(SCL-90-R), and the Spielberger's State-Trait Anxiety Inventory. In addition, a structured interview and a complete neurological examination, including the Hoehn and Yahr stage, the motor part of the Unified Parkinson's Disease Rating Scale(some selected scales of UPDRS part III), the Schwab and England Activities of Daily Living scale(ADL), and the Korean version of Mini-Mental State Examination were performed. Results: 1) Based on BDI score, subjects were divided into four groups:severely(40.7%), moderately(13.6%) and mildly(12.7%) depressive and non-depressive(33.1%). 2) The severity of depressive symptom in Parkinson's disease was positively correlated with Hoehn and Yahr(H & Y) stage(r=0.34, p<0.0001), the severity of motor symptom(r=0.35, p<0.0001), and trait anxiety inventory(r=0.33, p<0.001). On the other hand, the severity of depressive symptom was negatively correlated with educational level(r=-0.34, p<0.001), ADL(r=-0.37, p<0.0001) and Parkinson's disease quality of life (PDQL)(r=-0.69, p<0.0001). Among several clinical variables, the PDQL was the most influential factor predicting whether the depressive symptom was present or not. Conclusion: This study suggests that depressive symptom is very prevalent among patients with Parkinson's disease. Data from this study indicate that medical staffs who take care of patients with Parkinson's disease should pay attention to finding and treating depressive symptom among their patients. With appropriate psychiatric intervention, patient's depressive symptom can be minimized or alleviated and thus, the quality of life in these patients is likely enhanced.

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APPROXIMATE CONVEXITY WITH RESPECT TO INTEGRAL ARITHMETIC MEAN

  • Zoldak, Marek
    • Bulletin of the Korean Mathematical Society
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    • v.51 no.6
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    • pp.1829-1839
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    • 2014
  • Let (${\Omega}$, $\mathcal{S}$, ${\mu}$) be a probabilistic measure space, ${\varepsilon}{\in}\mathbb{R}$, ${\delta}{\geq}0$, p > 0 be given numbers and let $P{\subset}\mathbb{R}$ be an open interval. We consider a class of functions $f:P{\rightarrow}\mathbb{R}$, satisfying the inequality $$f(EX){\leq}E(f{\circ}X)+{\varepsilon}E({\mid}X-EX{\mid}^p)+{\delta}$$ for each $\mathcal{S}$-measurable simple function $X:{\Omega}{\rightarrow}P$. We show that if additionally the set of values of ${\mu}$ is equal to [0, 1] then $f:P{\rightarrow}\mathbb{R}$ satisfies the above condition if and only if $$f(tx+(1-t)y){\leq}tf(x)+(1-t)f(y)+{\varepsilon}[(1-t)^pt+t^p(1-t)]{\mid}x-y{\mid}^p+{\delta}$$ for $x,y{\in}P$, $t{\in}[0,1]$. We also prove some basic properties of such functions, e.g. the existence of subdifferentials, Hermite-Hadamard inequality.

MicroRNA-3200-5p Promotes Osteosarcoma Cell Invasion via Suppression of BRMS1

  • Li, Gen;Li, Li;Sun, Qi;Wu, Jiezhou;Ge, Wei;Lu, Guanghua;Cai, Ming
    • Molecules and Cells
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    • v.41 no.6
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    • pp.523-531
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    • 2018
  • Tumour metastasis is one of the most serious challenges of cancer as it is the major cause of mortality in patients with solid tumours, including osteosarcoma (OS). In this regard, anti-metastatic genes have potential for metastasis inhibition strategies. Recent evidence showed the importance of breast cancer metastasis suppressor 1 (BRMS1) in control of OS invasiveness, but the regulation of BRMS1 in OS remains largely unknown. Here, we used bioinformatics analyses to predict BRMS1-targeting microRNAs (miRNAs), and the functional binding of miRNAs to BRMS1 mRNA was evaluated using a dual luciferase reporter assay. Among all BRMS1-targeting miRNAs, only miR-151b, miR-7-5p and miR-3200-5p showed significant expression in OS specimens. Specifically, we found that only miR-3200-5p significantly inhibited protein translation of BRMS1 via pairing to the 3'-UTR of the BRMS1 mRNA. Moreover, we detected significantly lower BRMS1 and significantly higher miR-3200-5p in the OS specimens compared to the paired adjacent non-tumour bone tissues. Furthermore, BRMS1 and miR-3200-5p levels were inversely correlated to each other. Low BRMS1 was correlated with metastasis and poor patient survival. In vitro, overexpression of miR-3200-5p significantly decreased BRMS1 levels and promoted OS cell invasion and migration, while depletion of miR-3200-5p significantly increased BRMS1 levels and inhibited OS cell invasion and migration. Thus, our study revealed that miR-3200-5p may be a critical regulator of OS cell invasiveness.

Factors Influencing on the Attitude toward withdrawal of life-sustaining treatment of Nursing College Students (간호대학생의 연명치료 중단에 대한 태도에 영향을 미치는 요인)

  • Kim, Kyoung-Nam;Kang, Eun-Hee;Kim, Mi-Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.3
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    • pp.429-437
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    • 2019
  • This study was a descriptive study to investigate the factors influencing on attitude toward withdrawal of life-sustaining treatment of nursing students' consciousness of biomedical ethics, good death recognition and meaning of life. The subjects of this study were 293 nursing students attending college at P city. Data were collected for two weeks from May 1, 2018 to May 11, 2018. The statistical method was performed with SPSS WIN 22.0 using a complex sampling analysis, pearson's correlation coefficients, and a multiple regression analysis. The result of this study was significant positive correlation between attitude toward withdrawal of life-sustaining treatment and consciousness of biomedical ethics(r=.266, p<.001), good death recognition(r=.373, p<.001), meaning of life(r=.122, p=.037). The meaning of life was significant positive correlation consciousness of biomedical ethics(r=.294, p<.001), good death recognition(r=.230, p<.001). The good death recognition was significant positive correlation consciousness of biomedical ethics(r=.306, p<.001). Factors Influencing on the attitude toward withdrawal of life-sustaining treatment was good death recognition(${\beta}=.32$, p<.001) and consciousness of biomedical ethics(${\beta}=.16$, p=.004). These factors explained about 16% of the variance. Therefore it is necessary to develop an educational program to positively raise the attitude of consciousness of biomedical ethics and good death recognition.

Analysis of correlation between the inspiratory capacity of the National softball players and the bone density, bon mass, muscle power, muscle endurance (국가대표 소프트볼선수들의 흡기능력과 골밀도 및 골 질량 그리고 체간의 근력 및 근지구력의 상관관계 분석)

  • Kim, Hyun Chul;Park, Ki Jun
    • Journal of the Korean Society of Physical Medicine
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    • v.15 no.1
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    • pp.95-104
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    • 2020
  • PURPOSE: A prospective study was conducted to investigate the correlation between the inspiration ability, bone mineral density, lumbar muscle strength, and muscular endurance for the national softball athletes in the national training center. METHODS: The general characteristics of study subjects, inspiration ability, bone mineral density, muscle strength, and muscular endurance data were analyzed using descriptive statistics. In addition, the Pearson product moment correlation was performed to investigate the correlation between the inspiratory capacity, bone mineral density, muscle strength, and muscular endurance. RESULTS: The inspiration, flow rates, and volume were not correlated with the bone mass and bone mineral density. Inspiration and the flow rates and volume were not correlated with the bone mass and bone mineral density. On the other hand, inspiration was correlated with the Extensor muscles (r=.464, p=.006) at an angular velocity of 60°/s and the flexors (r=.463, p=.006) and extensor muscles (r=.615, p<.001) at an angular velocity of 180°/s. The flow rate was also correlated with the extensor muscles (r=.444, p=.009) at an angular velocity of 60°/s and with flexor muscles (r=.432, p=.011) and extensor muscles (r=.589, p<.001) at an angular velocity of 180°/s. Finally, the volume was correlated at the extensor muscles at an angular velocity of 180°/s (r=.534, p=.001). CONCLUSION: The correlation between the inspiratory capacity, bone mineral density, muscle strength, and muscular endurance of softball athletes did not correlate with the bone mass and bone density. On the other hand, the lumbar muscle strength increased with increasing inspiratory capacity.

The Structure of Walled Signed Brauer Algebras

  • Kethesan, Balachandran
    • Kyungpook Mathematical Journal
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    • v.56 no.4
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    • pp.1047-1067
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    • 2016
  • In this paper, a new class of diagram algebras which are subalgebras of signed brauer algebras, called the Walled Signed Brauer algebras denoted by ${\overrightarrow{D}}_{r,s}(x)$, where $r,s{\in}{\mathbb{N}}$ and x is an indeterminate are introduced. A presentation of walled signed Brauer algebras in terms of generators and relations is given. The cellularity of a walled signed Brauer algebra is established. Finally, ${\overrightarrow{D}}_{r,s}(x)$, is quasi- hereditary if either the characteristic of a field, say p, p = 0 or p > max(r, s) and either $x {\neq}0$ or x = 0 and $r{\neq}s$.

Phylogenetic Analysis of Phyllospadix iwatensis Based on Nucleotide Sequences Encoding 18S rRNA and ITS-1

  • Kim, Jong-Myoung;Choi, Chang-Geun
    • Fisheries and Aquatic Sciences
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    • v.13 no.4
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    • pp.272-277
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    • 2010
  • Seagrasses are marine angiosperms of ecological importance in providing shelter and food to aquatic species as well as maintaining the carbon cycle on earth. Phyllospadix iwatensis is a seagrass of the family Zosteraceae and is distributed along the eastern coast of Korea. The nucleotide sequences of P. iwatensis nuclear genes encoding 18S ribosomal RNA (rRNA) and internal transcribed spacer-1 (ITS-1) were determined for molecular phylogenetic analysis. Genomic DNA was isolated from P. iwatensis and used for PCR amplification of 18S rRNA and ITS-1. Examination of the 18S rRNA sequence of P. iwatensis showed a close (99% similarity) relationship to Zostera noltii, another genus of Zosteraceae, but a distant (84% similarity) evolutionary relationship to other macroalgal Laminariales species. Further discrepancies found in ITS-1 nucleotide sequences between closely related species indicate that the sequence information could be used for species identification.

Taxonomical Classification and Species-specific Detection of Genus Some Phellinus using Phylotype (Phylotype에 의한 수종의 Phellinus속의 분류체계 확립 및 종간구별을 위한 신속동정법 개발)

  • Kim, Cheng-Yun;Lee, Jae-Yun;Kim, Gi-Young;Lee, Ki-Won;Park, Jae-Min;Kim, Mun-Ok;Lee, Tae-Ho;Lee, Jae-Dong
    • The Korean Journal of Mycology
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    • v.31 no.3
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    • pp.121-128
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    • 2003
  • This study was carried out to identify the phylogenetic relationship of Phellinus species and to know its distribution by comparing the DNA sequences of internal transcribed spacer regions(ITS1 and IST2) and 5.8S ribosomal DNA (rDNA) repeat unit. The Phellinus species had their specific sequences in IST1 and 2 regions depending on suedes. The comparison of the ITS sequences of standard strains indicated that the sequences of ITS1 were more variable than those of ITS2. Nine strains of the commercial products of Phellinus species used in this study were identified as P. lintues, P. baumii, P. igniarius, and P. pini. Most of commercial species were P. pini and P. baumii, and P. gilvus was not found. Also, P. linteus was only found in form of mycelial culture rather than fruiting body. Moreover, the species-specific primers were designed based on ITS sequence data. Each species-specific primers were bound in P. lintues(ITSF-PL2R), P. baumii(PB1F-ITS4R), P. igniarius(IF1-IR3), P. pini(PF1-PR3), and P. gilvus(GF2-GR4), respectively. These primer sets would be useful fer the detection of specific-species among unidentified Phellinus species rapidly.

INDEPENDENTLY GENERATED MODULES

  • Kosan, Muhammet Tamer;Ozdin, Tufan
    • Bulletin of the Korean Mathematical Society
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    • v.46 no.5
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    • pp.867-871
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    • 2009
  • A module M over a ring R is said to satisfy (P) if every generating set of M contains an independent generating set. The following results are proved; (1) Let $\tau$ = ($\mathbb{T}_\tau,\;\mathbb{F}_\tau$) be a hereditary torsion theory such that $\mathbb{T}_\tau$ $\neq$ Mod-R. Then every $\tau$-torsionfree R-module satisfies (P) if and only if S = R/$\tau$(R) is a division ring. (2) Let $\mathcal{K}$ be a hereditary pre-torsion class of modules. Then every module in $\mathcal{K}$ satisfies (P) if and only if either $\mathcal{K}$ = {0} or S = R/$Soc_\mathcal{K}$(R) is a division ring, where $Soc_\mathcal{K}$(R) = $\cap${I 4\leq$ $R_R$ : R/I$\in\mathcal{K}$}.