• 대한화학회지
• /
• 제46권1호
• /
• pp.46-51
• /
• 2002

$Ni(II){\cdot}Gly$-Gly-His(Arg)COOH와 $Cu(II){\cdot}Gly$-Gly-His(Arg)COOH 형태의 금속펩타이드를 이용하여 P. alcaligenes에서 얻은 5S rRNA의 구조를 조사하였다. 그 결과 금속 펩타이드들은 5S rRNA의 줄기-고리 구조에서 염기쌍을 이루지 않거나 불안정하게 이루는 부분을 선택적으로 변형시켰다. 금속펩타이드의 선택성은 중심 금속이 Ni(II)인 경우와 Cu(II)인 경우에 차이가 거의 없었다. 금속펩타이드를 이용한 절단 결과를 금속 착물 M(II)CR을 이용한 결과와 비교하면 금속펩타이드에 의한 선택성이 더 크게 나타났다. 금속펩타이드와 금속착물을 이용한 절단 결과로부터 P. alcaligenes에서 얻은 5S rRNA의 이차구조를 살펴보았다.

• 여성건강간호학회지
• /
• 제6권4호
• /
• pp.566-578
• /
• 2000

This study was conducted to ascertain infant's sleep and feeding patterns for the purpose of building up the positive parent-child relationship and setting up a preliminary parenting education program. The subjects were 16 infants who were cared for in their houses. The data was collected using NCASA developed by Barnard et al. from October 1st to December 3lth, 1999. The analysis of data was done with SPSSWIN for descriptive statistics and t-test, ANOVA, Correlation Analysis. The result were as follows: 1. The average day sleep of the infant was 9.51 hours, night sleep was 6.27 hours, and total sleep was 15.84 hours. The longest period of day sleep was 3.02 hours, and the longest period of night sleep was 3.72 hours. The regularity of day sleep was 34.78%, night sleep was 61.72% and total was 43.76%. 2. The frequency of daytime feeding was 5.13 times, nighttime was 2.44 times and total was 7.38 times. The regularity of feeding was 52.14%. 3. In the correlation between sleep and feeding patterns, night sleep was negatively correlated with feeding method(r=-.52, P<0.05), the longest period of day sleep was negatively correlated with feeding method(r=-.73, P<0.001), feeding frequency(r=-.60, P<0.05), the regularity of feeding(r=-.70, P<0.001). The longest period of night sleep was negatively correlated with feeding frequency (r=-.53, P<0.05). Feeding method was positively correlated with feeding frequency(r=.71, P<0.001), the regularity of feeding(r=.57, P<0.05). Day sleep was positively correlated with total sleep(r=.93, P<0.001), the regularity of total sleep was positively correlated with the longest period of day sleep(r=.54, P<0.05), total sleep(r=.65, P<0.001). The regularity of feeding was positively correlated with feeding method(r=.57, P<0.05), total feeding frequency(r=.50, P<0.05), the frequency of daytime feeding(r=.61, P<0.05). Feeding method was positively correlated with total feeding frequency(r=.71, P<0.001). In conclusion, the study showed that infants slept more in the nighttime than in the daytime, but after 3 months the pattern changed and showed that nighttime sleep was increased. Also the regularity of night sleep was increased with the infant's age. Total feeding frequency was decreased with the infant's age, and the regularity of feeding was increased in infants who slept shorter periods in the daytime than in the nighttime.

• 대한간호학회지
• /
• 제36권6호
• /
• pp.925-932
• /
• 2006

Purpose: The purpose of this study was to identify the relationship between depression, perceived stress, fatigue and anger in clinical nurses. Method: A descriptive survey was conducted using a convenient sample. Data was collected by questionnaires from four hundred clinical nurses who worked at a university hospital. Radloff's CES-D for depression, Cohen, Kamarck & Mermelstein's Perceived Stress Scale, VAS for Fatigue, and Spielberger's STAXI for anger were used. The data was analyzed using the pearson correlation coefficient, students' t-test, ANOVA, and stepwise multiple regression with SPSS/WIN 12.0. Result: The depression of clinical nurses showed a significantly positive correlation to perceived stress(r=.360, p=.000), mental fatigue(r=.471, p=.000), physical fatigue(r=.350, p=.000), trait anger(r=.370, p=.000), anger-in expression(r=.231, p=.000), and anger-control expression(r=.120, p=.016). There was a negative correlation between depression and age(r=-.146, p=.003). The mean score of depression of nurses, 26, was a very high score and 40.8% of clinical nurses were included in a depression group. The main significant predictors influencing depression of clinical nurses were mental fatigue, trail anger, perceived stress, anger-in expression, and state anger, which explained about 32.7%. Conclusion: These results indicate that clinical nurses with a high degree of perceived stress, mental fatigue and anger-in expression are likely to be depressed.

• 한국응용과학기술학회지
• /
• 제39권6호
• /
• pp.839-852
• /
• 2022

본 연구는 중소병원간호사가 급격하게 변화하는 의료환경에 유연하게 대처할 수 있도록 업무 스트레스 및 회복탄력성, 간호업무성과를 파악하고 영향요인을 확인하기 위한 서술적 조사연구이다. 연구대상자는 S지역에 소재하는 4개 중소병원에서 근무하는 간호사 219명이었으며, 구조화된 설문지를 이용하여 조사하였다. 수집된 자료는 기술통계, t-test, ANOVA, Pearson's 상관관계 분석 및 다중회귀분석을 이용하여 분석하였다. 중소병원 간호사의 업무 스트레스와 간호업무성과는 음의 상관관계(r=-0.150, p<.05), 업무 스트레스와 회복탄력성은 양의 상관관계(r=0.160, p<.05). 간호업무성과는 회복탄력성과 양의 상관관계를 보였다(r=0.351, p<.01). 간호업무성과에 영향을 미치는 변수는 회복탄력성(𝛽=.231, p<.01)이였으며, 설명력은 17.4%로 나타났다(Adj.R²=0.174, p<.001). 따라서 간호사의 간호업무성과를 향상시키기 위해서는 회복탄력성을 증가시킬 필요가 있으며, 이를 위해서는 간호사 개인의 역량에 맞는 다양한 교육 프로그램을 개발하여 적용할 필요가 있겠다.

• 대한수학회보
• /
• 제36권2호
• /
• pp.287-303
• /
• 1999

The general solution of the functional equation f1(pr, qs) + f2(ps, qr) = g(p,q) + h(r,s) for p, q, r, s $\in$] 0, 1[will be investigated without any regularity assumptions on the unknown functions f1, f2, g, h:]0.1[->R.

• Journal of Microbiology and Biotechnology
• /
• 제31권8호
• /
• pp.1098-1108
• /
• 2021

The literature indicates that LINC00174 promotes the growth of colorectal cancer (CRC) cells, but its research needs to be enriched. We tried to explore the function and mechanism of LINC00174 in CRC cell proliferation and migration. Bioinformatics analysis predicted the binding relationship and expressions of lncRNA, miRNA and mRNA. Clinical study analyzes the relationship between LINC00174 and clinical data characteristics of CRC patients. The expressions of LINC00174, miR-3127-5p and E2F7 were verified by RT-qPCR, and the combination of the two was verified by dual luciferase analysis and RNA immunoprecipitation as needed. Western blot was used to detect the expression of EMT-related protein and E2F7 protein. Functional experiments were used to evaluate the function of the target gene on CRC cells. LINC00174 was up-regulated in CRC clinical samples and cells and was related to the clinical characteristics of CRC patients. High-expression of LINC00174, contrary to the effect of siLINC00174, promoted cell viability, proliferation, migration and invasion, up-regulated the expressions of N-Cadherin, Vimentin, E2F7, and inhibited the expression of E-Cadherin. MiR-3127-5p was one of the targeted miRNAs of LINC00174 and was down-regulated in CRC samples. In addition, miR-3127-5p mimic partially reversed the malignant phenotype of CRC cells induced by LINC00174. Besides, E2F7 was a target gene of miR-3127-5p, and LINC00174 repressed miR-3127-5p to regulate E2F7. Our research reveals that LINC00174 affected the biological characteristics of CRC cells through regulated miR-3127-5p/ E2F7 axis.

• 한국작물학회:학술대회논문집
• /
• 한국작물학회 1990년도 춘계 학술대회지
• /
• pp.38-39
• /
• 1990

• 한국작물학회:학술대회논문집
• /
• 한국작물학회 1990년도 춘계 학술대회지
• /
• pp.64-65
• /
• 1990

• 한국산학기술학회논문지
• /
• 제21권4호
• /
• pp.82-90
• /
• 2020

본 연구는 간호대학생들의 공감능력, 자기조절력, 스마트폰 의존성이 대인관계에 미치는 영향을 파악하기 위한 서술적 조사연구이다. 연구 자료는 A시 S대학교에 재학 중인 간호대학생 157명을 대상으로 구조화된 설문지로 조사하였다. 자료수집 기간은 2019년 5월 27일에서 5월 31일까지이며, 수집된 자료는 SPSS WIN 14.0을 이용하여 Independent t-test, One-way ANOVA, Pearson correlation coefficients, Stepwise multiple regression으로 분석하였다. 연구결과, 대상자의 성적에 따라 자기조절력(F=5.319, p=.006)과 스마트폰 의존성(F=4.854, p=.009) 정도의 차이가 나타났고, 스마트폰 사용시간에 따라 스마트폰 의존성(t=-3.381, p<.001) 차이가 있었다. 연령은 자기조절력과 순상관관계(r=.194, p=.015)를, 스마트폰 의존성과는 역상관관계(r=-.223, p=.005)를 보였다. 또한 자기조절력은 공감능력(r=.244, p<.01)과 대인관계(r=.540, p<.001)와는 순상관관계를 보였으며 스마트폰 의존성(r=-.432, p<.001)과는 역상관관계를 보였다. 공감능력과 대인관계는 순상관관계(r=.476, p<.001)에 있었다. 회귀분석 결과, 대인관계에 영향을 주는 요인은 자기조절력(β=.477, p<.001), 공감능력(β=.359, p<.001), 스마트폰 사용시간(β=.208, p<.01)이었으며, 총 설명력은 45.0%(F=12.029, p<.01)이었다. 본 연구를 통해 간호대학생의 대인관계를 향상하기 위한 프로그램에서는 자기조절력, 공감능력, 스마트폰 사용시간에 대한 고려가 필요할 것으로 사료된다.

• 대한통합의학회지
• /
• 제12권1호
• /
• pp.73-81
• /
• 2024

Purpose : The purpose of this study was to identify the degree of occupational therapists' professional identity and examine the correlation between empowerment and burn out. We also investigated the effects of the occupational therapists' professional identity on empowerment and burn out. Through these assessments, we aimed to highlight the importance of professional identity and find methods to improve empowerment and reduce burn out in occupational therapists. Methods : The study was conducted from October 19 to from November 11, 2023. General characteristics, professional identity, empowerment, and burn out were examined using frequency analysis and descriptive statistics. The correlation between these factors was analyzed using Pearson's correlation coefficient. Multiple regression analysis was used to identify factors influencing empowerment and burn out. An α value =.05 was used to verify statistical significance. Results : First, Professional identity was an average 3.24±.37. Second, a significant correlation was found between professional identity and empowerment (r=.417, p<.01) and burn out (r=-.377, p<.01). As a result of the relationship between professional identity sub-factors and empowerment in professional organization (r=.270, p<.01),, belief in self-regulation (r=.258, p<.01), vocational consciousness (r=.348, p<.01), and belief in autonomy (r=.308, p<.01) showed a statistically significant correlation. Professional identity sub-factors were significantly correlated with burnout, professional organization (r=-.199, p<.05), belief in public service (r=-.153, p<.05), belief in self-regulation (r=-.334, p<.01), vocational consciousness (r=-.250, p<.01), and belief in autonomy (r=-.293, p<.01) showed a significant correlation. Third, professional identity sub-factors influencing empowerment were vocational consciousness (β=.154, p<.05) and belief in autonomy (β=.135, p<.05), and those influencing burnout were belief in self-regulation (β=-.389, p<.01) and belief in autonomy (β=-.244, p<.01). Conclusion : The study findings demonstrated that professional identity affects empowerment and burn out. Therefore, continuous study on the professional identity of occupational therapists is warranted.