• Title/Summary/Keyword: NQS

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Carrier-Mediated Tissue Distribution and Blood-Brain Barrier Transport of New Quinolones

  • Tsuji, Akira
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1997.04a
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    • pp.57-63
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    • 1997
  • Animal and clinical investigations have shown that fluoroquinolones, new quinolone antibacterial agents (NQs), are well absorbed across the intestinal tract, with a bioavailability of 60-90% after oral administration. Although some types of carrier-mediated intestinal transport mechanisms have been reported for enoxacin (ENX), ofloxacin (OFLX) and sparfloxacin (SPFX), recent results using a human intestinal epithelial cell line, Caco-2, indicated a passive or nonsaturable transport of SPFX, one of the most hydrophobic NQs. The mechanism underlying the intestinal absorption of NQs is still largely unknown. The distribution of NQs into peripheral tissues including erythrocytes is very rapid and their tissue-to-plasma concentration ratios (Kp) are considerably larger than those of inulin (an extracellular fluid space marker), in spite of almost complete ionization of NQs at the physiological pH. Our findings suggest that OFLX and lomefloxacin (LFLX) are taken up by rat erythrocytes via a transport system common to that of a water-soluble vitamin, nicotinic acid.

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Cross-Linked Enzyme Crystal(CLEC);Stability of Horse Liver Alcohol Dehydrogenase CLEC against Electron Transfer Mediators (격자화 효소결정;전자이동 중개체에 대한 알콜 탈수소격자화 효소결정의 안정도)

  • Lee, Kang Min
    • Journal of the Korean Chemical Society
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    • v.45 no.1
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    • pp.61-66
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    • 2001
  • Stabilized Cross-linking Enzyme Crystals(CLEC) can be used as not only biocatalysts but also as enzyme sensors. PMS(Phenylmethyl Sulfate)was shown more efficience than any other electron mediator transfers toward HLADH(Horse Liver Alcohol Dehydrogenase)that were examined. NQS(naphtoquinonesulphonate), phenothiazine and ferrocene aldehyde had respectively just 52%, 37%, 35% electron transfer efficiency as compared to PMS . HLADH-CLEC was very stable toward elctron transfer mediators such as PMS, NQS and ferrocene aldehyde in which HLADH-solution was unstable.

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The Implement and Optimization of NQS & Load balancing in NEC System (NEC 시스템에서 NQS 및 Load balancing 최적화)

  • Lee, Young-Joo;Lee, Sang-Dong;Kim, Jung-Kwon
    • Proceedings of the Korea Information Processing Society Conference
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    • 2003.11a
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    • pp.427-430
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    • 2003
  • 작업관리 시스템인 배치처리 시스템은 한정된 공유자원을 동시에 요구하는 사용자들에게 시스템의 자원을 효율적으로 배분하여 주며, 제시된 다수의 작업들을 순차적으로 수행시켜 준다. 이러한 작업관리 시스템을 시스템 규모 사용자의 요구 조건에 맞게 최적화함으로써 시스템의 자원을 최대한 이용할 수 있게 하며, 다양한 사용자 요구에 적절한 자원 배분할 수 있도록 정의되어야 한다. NQS방식을 개선시켜 이종 모델로 구성된 NEC SX-5 및 SX-6을 단일시스템처럼 관리할 수 있도록 하였으며 다수의 연동 계산을 원활히 수행키 위한 큐 차등화 서비스방식을 적용시켜 사용자 대기 시간을 최소화시켰다. 본 논문에서는 NQS를 사용하여 이종 다중 노드의 연동 구성 방법과 이것의 최적화 방법 그리고, 노드간 load balancing을 최적 수행 방법 등을 소개한다.

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A new CAD-compatible non-quasi-static MOS tansient model (새로운 CAD용 Non-Quasi-Static MOS 과도 전류 모델)

  • 권대한;류윤섭;김기혁;황성우
    • Journal of the Korean Institute of Telematics and Electronics D
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    • v.34D no.12
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    • pp.31-38
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    • 1997
  • A new CAD-compatible non-quasi-static (NQS) MOS transient model is presented. A new type of weighted residual method, the collcoatin method, is adopted to obtian an approximate ordinary differntial equation from the continuity eqation. Contrasting to the conventional NQS models, the new model can directly include the variatin of the depletion charge and the derived transient current sare expressed with only physically meaningful variables. The new model predicts transient behaviors reasonably well in the calculation including cutoff regions where the depletion charge rapidly changes.

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The NQS Design and Implementation of Load balancing in Multi Node (멀티 노드에서의 NQS Loadbalancing 설계 및 구현)

  • Lee, Yuong-Joo;Sung, Jin-Woo;Lee, Sang-Dong;Kim, Joong-Kwon
    • Proceedings of the Korea Information Processing Society Conference
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    • 2004.05a
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    • pp.1673-1676
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    • 2004
  • 시스템의 한정된 자원을 다수의 사용자들에게 효율적으로 분배하기 위해서 작업관리 시스템이 사용된다. 이러한 작업관리 시스템은 그 종류가 여러 가지가 사용되고 있는데, 시스템의 종류나 특성에 따라서 적당한 작업관리 시스템을 사용한다. NEC 시스템에서는 작업관리 시스템으로 NQS를 사용하는데, 이 시스템을 이용하여 시스템의 한정된 자원을 다양한 사용자들의 요구에 적절히 자원을 배분 할 수 있도록 설계하고 이러한 배분 방식으로 각각의 노드에서 균형 있게 작업이 실행될 수 있도록 구현한 노드간 최적 분배 방법 등을 기술한다.

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Comparison of the nutrition quotient by types of eating behavior among male and female university students in Gwangju (광주 지역 남녀 대학생의 섭식 행동 유형별 영양 지수의 비교)

  • Geum-Bi Ryu;Young-Ran Heo
    • Journal of Nutrition and Health
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    • v.56 no.3
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    • pp.277-287
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    • 2023
  • Purpose: This study was conducted to investigate the eating behavior (EB) and nutritional status of university students in Gwangju, and to compare their nutrition quotients (NQs) and problems according to their EB types. Methods: The subjects were 219 (127 female and 92 male) undergraduate students from Gwangju. The Student's t-test was used to compare the EB levels according to gender, and Pearson's χ2 test was used to compare the distribution of EB types by gender. A gender-adjusted analysis of covariance (ANCOVA) was conducted to examine the difference in NQs by EB types. Results: First, there were significant differences in the EB scores and the distribution of EB types according to gender. Female students showed higher levels of emotional (Emo) and external (Ext) EBs than the male students, and Emo, Ext, and combined (Com) EB types were more evident among female rather than male students. Second, there was a difference in NQs according to the EB types. The Emo EB type subjects had a lower NQ than those of the restrained (Res) EB type and showed significant differences in diversity and dietary behavior. Specifically, the Emo EB type subjects displayed significantly lower efforts to maintain a healthy diet and subjective health status than the Com EB type and their levels of checking nutrition labels, hand washing, and water intake were significantly lower than that of the Res EB type. The Ext EB type showed significantly lower moderation of Ramyeon and sweetened drink intake than the Res and Com EB types. Conclusion: The level of EBs and the distribution of EB types varied according to gender, and the NQs were different according to EB types. The results of this study are expected to contribute to the establishment of customized strategies for improvement by identifying major nutritional problems by gender and the EB types of university students.

Small-Signal Modeling of Gate-All-Around (GAA) Junctionless (JL) MOSFETs for Sub-millimeter Wave Applications

  • Lee, Jae-Sung;Cho, Seong-Jae;Park, Byung-Gook;Harris, James S. Jr.;Kang, In-Man
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.12 no.2
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    • pp.230-239
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    • 2012
  • In this paper, we present the radio-frequency (RF) modeling for gate-all-around (GAA) junctionless (JL) MOSFETs with 30-nm channel length. The presented non-quasi-static (NQS) model has included the gate-bias-dependent components of the source and drain (S/D) resistances. RF characteristics of GAA junctionless MOSFETs have been obtained by 3-dimensional (3D) device simulation up to 1 THz. The modeling results were verified under bias conditions of linear region (VGS = 1 V, VDS = 0.5 V) and saturation region (VGS = VDS = 1 V). Under these conditions, the root-mean-square (RMS) modeling error of $Y_{22}$-parameters was calculated to be below 2.4%, which was reduced from a previous NQS modeling error of 10.2%.

HPC environment Design and Implementation for Efficient Job Processing in an NEC system

  • Choi, Ji-Woo;Park, Jung-Oung;Kim, Hyun-Joung;Yang, Jong-Won;Ha, Keyng-Ju;Seo, Chang-Ho
    • The Journal of Korean Association of Computer Education
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    • v.13 no.4
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    • pp.69-75
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    • 2010
  • As several users use a system simultaneously, a job management system is used to prevent exclusive uses in the system by a certain user and share entire resources for all users. The job management system is a type of scheduler that distributes limited resources for each job inquire efficiently. The system can be classified as different types and is to be properly selected according to the characteristics of systems and jobs. An NEC system is a job management system and usually applies NQS. The job management system has several queues, which are able to process jobs through distributed resources in which the efficiency of such job processing can be varied according to the composition of these queues. This study designs and configures differentiated queues according to service levels in order to improve the efficiency of the entire system as NQS is designed and that performs job processing. Also, this study analyze the performance of the job processing.

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Accurate parameter extraction method for FD-SOI MOSFETs RF small-signal model including non-quasi-static effects (NQS효과를 고려한 FD-SOI MOSFET의 고주파 소신호 모델변수 추출방법)

  • Kim, Gue-Chol
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.11 no.10
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    • pp.1910-1915
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    • 2007
  • An accurate and simple method to extract equivalent circuit parameters of fully-depleted silicon-on-insulator MOSFETs small-signal modeling operating at RF frequencies including the non-quasi static effects is presented in this article. The advantage of this method is that a unique and physically meaningful set of intrinsic equivalent circuit parameters is extracted by de-embedding procedure of extrinsic elements such as parasitic capacitances and resistances of MOSFETs from measured S-parameters using simple Z- and Y- matrices calculations. The calculated small-signal parameters using the presented extraction method give modeled Y-parameters which are in good agreement with the measured Y-parameters from 0.5 to 20GHz.

Mining Single Nucleotide Polymorphisms from Silkworm EST Data

  • Qingyou, Xia;Tingcai, Cheng;Jifeng, Qian;Zheyang, Zhou;Zhonghuai, Xiang
    • Proceedings of the Korean Society of Sericultural Science Conference
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    • 2003.10a
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    • pp.23-23
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    • 2003
  • We made use of 81, 635 expressed sequence tags (ESTs) derived from 12 different cDNA libraries of Bombyx mori to identify high-quality candidate single nucleotide polymorphisms (SNPs). By PHRAP assembling, we obtained 12, 980 contigs containing 11, 531 contigs assembled by more than one reads. From 117 contig sequences, which were assembled by 1, 576 high-quality reads base-called with PHRED, we identified 101 candidate SNPs and 27 single base insertions/deletions based on a neighborhood quality standard(NQS) of SNP. (omitted)

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