• 제목/요약/키워드: Mode of action

검색결과 657건 처리시간 0.032초

Trichoderma koningii에서 분리한 $\beta$-glucosidase의 작용양상 (The Action Mode of $\beta$-glucosidase Purified from Trichoderma koningii)

  • 정춘수;최지영;이헌주;맹필재;한인섭;강사욱;하영칠
    • 미생물학회지
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    • 제36권1호
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    • pp.8-13
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    • 2000
  • Trichoderma koningii ATCC 26113에서 분비되는 효소인 $\beta$-glucosidase를 cellobiose, sophorose, laminaribiose 및 gentiobiose 등의 기질과 반응시킨 후 효소의 transglycosylation 반응 산물을 분석하였다. 각각의 기질로부터 생성된 이당체(dimer)들을 HPLC로 분리하고 $^(1)H$-NMR spectroscopy를 통하여 분석하였다. Cellobiose를 기질로 사용하여 효소와 반응시켰을 때 그 산물에는 laminaribiose, sophorose 및 gentiobiose가 포함되었음을 확인할 수 있었다. Laminaribiose, sophorose 및 gentiobiose를 기질로 사용하였을 경우에 효소는 transglycosylation 반응을 통하여 새로운 $\beta$-glycosidic 결합을 갖는 이당체들을 생성하였다. 효소반응에 의하여 누적되는 이당체의 양은 생성속도보다는 분해속도에 의하여 결정되는 것으로 나타났다.

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진동모드를 이용한 사장교의 손상 검색 (Damage Detection in Cable-Stayed Bridges Using Vibration Modes)

  • 공민식;가훈;손석호;임성순
    • 한국구조물진단유지관리공학회 논문집
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    • 제10권6호
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    • pp.113-123
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    • 2006
  • 사장교가 장경간으로 시공됨에 따라 대형화 되고 지진하중, 풍하중 및 차량하중 등 동적 하중에 의해 유발되는 진동현상에 취약한 단점이 나타난다. 이러한 하중 등에 의해 발생된 구조 손상은 구조물의 진동모드 특성에 영향을 미치게 된다. 기존의 정밀안전진단 기술을 이용하여 사장교의 구조 손상을 검색하고 평가하는 것은 상당한 비용과 시간이 소요될 뿐만 아니라 전체적인 구조거동 특성의 변화를 발견하기 어려울 것이다. 따라서 본 연구는 사장교에 대하여 구조손상 전의 진동모드 특성치와 구조손상 후의 진동모드 특성치를 이용하여 구조거동 특성의 변화를 검토하고 구조손상 검색을 수행하였다.

분말녹용의 약물활성 연구(I) (Pharmacological Studies on Powdered Whole Part of Unossified Antler)

  • 신국현;이은방;김재현;정명숙;조성익
    • 생약학회지
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    • 제20권3호
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    • pp.180-187
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    • 1989
  • Systematic pharmacological studies on powdered whole part of unossified antler obtained from Cervus nippon Temminck var. mantchuricus have been carried out in mice and rats. Powdered antler, with a single oral administration, showed a very weak acute and subacute toxicity; its MLD being >5g/kg orally in mice. On daily oral treatments of the antler for 14 days, it did not cause any significant differences in body weight gain, various organ weights and serum transaminase activities compared to those of the control rats. Powdered antler, with a single oral administration, showed a remarkable analgesic activity as evaluated by writhing syndrome and tail-pressure test, a weak CNS depressant activity as well as a weak immunopotentiating action as evaluated by carbon clearance test in mice. Powdered antler, with repeated treatments, showed a moderate antifatigue effect against immobilized stress and showed significant increases in both adrenal weight and its ascorbic acid content in rats, suggesting that the mode of antifatigue effect of antler is related to adrenal and its components.

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한국형 틸팅열차의 신뢰성기반 유지보수 체계 구축에 관한 연구 (A Study on the Construction of Reliability Centered Maintenance System for Korean Tilting Train)

  • 서승일;문형석;엄기영
    • 한국철도학회논문집
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    • 제10권5호
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    • pp.520-526
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    • 2007
  • 본 논문에서는 한국형 틸팅열차의 유지보수 활동을 위해 신뢰성기반유지보수체계를 제안하였다. 열차시스템을 3단계의 교체 부품 단위로 분류하고, 각 단위에 대해 기능블록도를 작성한 후 고장모드 영향 분석을 실시하였다. 각 단위의 심각도를 결정한 후 유지보수 정책을 제안하였으며, 틸팅열차를 위한 유지보수 기준을 정하고, 실제 사례를 제시하였다. 제안된 신뢰성기반유지보수체계는 기존 유지보수 체계와도 호환성을 갖고 있으며, 안전성 향상과 유지보수 활동 효율화에 기여할 수 있다.In this paper, a reliability centered maintenance (RCM) system is proposed to perform maintenance action for Korean Tilting Train. The train system was divided into line replaceable units up to three steps. Functional block diagrams were drawn and failure mode effect analysis for the units was carried out. The criticality of each unit was determined and a maintenance policy was proposed. Maintenance and repair criteria for the tilting train were determined and an example was presented. The proposed RCM system is compatible with the previous maintenance system and contributes to improvement of safety and efficiency of maintenance action.

Carrier Based Common Mode Voltage Reduction Techniques in Neutral Point Clamped Inverter Based AC-DC-AC Drive System

  • Ojha, Amit;Chaturvedi, Pradyumn;Mittal, Arvind;Jain, Shailendra
    • Journal of Power Electronics
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    • 제16권1호
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    • pp.142-152
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    • 2016
  • Common mode voltage (CMV) generation is a major problem in switching power converter fed induction motor drive systems. CMV is the zero sequence voltage generated due to the switching action of power converters. Even a small magnitude of CMV with a high rate of change may circulate large bearing currents which may damage a machine's bearings and shorten its life. There are several methods of controlling CMV. This paper presents 3-level sinusoidal pulse width modulation based techniques to control the magnitude and rate of change of CMV in multilevel AC-DC-AC drive systems. Simulation and experimental investigations have been presented to validate the performance of proposed technique to control CMV in 3-level neutral point clamped inverter based AC-DC-AC system.

Super-Twisting Sliding Mode Control Design for Cascaded Control System of PMSG Wind Turbine

  • Phan, Dinh Hieu;Huang, ShouDao
    • Journal of Power Electronics
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    • 제15권5호
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    • pp.1358-1366
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    • 2015
  • This study focuses on an advanced second-order sliding mode control strategy for a variable speed wind turbine based on a permanent magnet synchronous generator to maximize wind power extraction while simultaneously reducing the mechanical stress effect. The control design based on a modified version of the super-twisting algorithm with variable gains can be applied to the cascaded system scheme comprising the current control loop and speed control loop. The proposed control inheriting the well-known robustness of the sliding technique successfully deals with the problems of essential nonlinearity of wind turbine systems, the effects of disturbance regarding variation on the parameters, and the random nature of wind speed. In addition, the advantages of the adaptive gains and the smoothness of the control action strongly reduce the chatter signals of wind turbine systems. Finally, with comparison with the traditional super-twisting algorithm, the performance of the system is verified through simulation results under wind speed turbulence and parameter variations.

A study on the Nonlinear Normal Mode Vibration Using Adelphic Integral

  • Huinam Rhee;Kim, Jeong-Soo
    • Journal of Mechanical Science and Technology
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    • 제17권12호
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    • pp.1922-1927
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    • 2003
  • Nonlinear normal mode (NNM) vibration, in a nonlinear dual mass Hamiltonian system, which has 6$\^$th/ order homogeneous polynomial as a nonlinear term, is studied in this paper. The existence, bifurcation, and the orbital stability of periodic motions are to be studied in the phase space. In order to find the analytic expression of the invariant curves in the Poincare Map, which is a mapping of a phase trajectory onto 2 dimensional surface in 4 dimensional phase space, Whittaker's Adelphic Integral, instead of the direct integration of the equations of motion or the Birkhoff-Gustavson (B-G) canonical transformation, is derived for small value of energy. It is revealed that the integral of motion by Adelphic Integral is essentially consistent with the one obtained from the B-G transformation method. The resulting expression of the invariant curves can be used for analyzing the behavior of NNM vibration in the Poincare Map.

Influences of the Filter Effect on Pulse Splitting in Passively Mode-Locked Fiber Laser with Positive Dispersion Cavity

  • Chen, Xiaodong
    • Journal of the Optical Society of Korea
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    • 제19권2호
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    • pp.130-135
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    • 2015
  • Based on the extended nonlinear Schr$\ddot{o}$dinger equation, the influences of the filter effect on pulse splitting in a passively mode-locked erbium-doped fiber laser with positive dispersion cavity are investigated theoretically. Numerical results show that, as the bandwidth of the spectral filter decreases, the nonlinear chirp appended to the pulse increases under the combined action of the filter effect of the super-Gaussian spectral filter and the self-phase modulation effect. On further decreasing the bandwidth, the wave breaking of the pulse takes place. In addition, by varying the pump power of the laser or the profile of the spectral filter, the influences of the filter effect on pulse splitting also change accordingly.

온칩 DC-DC 변환기를 위한 전류 비교 방식의 센서 (A Sensing Scheme Utilizing Current-Mode Comparison for On-Chip DC-DC Converter)

  • 김형일;송하선;김범수;김대정
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2006년도 하계종합학술대회
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    • pp.529-530
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    • 2006
  • An efficient sensing scheme adoptable in DC-DC converter is described. The output voltage of the whole DC-DC converter is fed back to the input voltage of the sensor. The comparison in the sensor is accomplished by a current push-pull action. With a fixed reference, the comparator can be embodied based on (W/L) ratios. The current-mode scheme benefits the system better than a conventional voltage-mode one in terms of small area, low power consumption.

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Composite Control for Inverted Pendulum System

  • Kwon, Yo-Han;Kim, Beom-Soo;Lee, Sang-Yup;Lim, Myo-Taeg
    • Transactions on Control, Automation and Systems Engineering
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    • 제4권1호
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    • pp.84-91
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    • 2002
  • A new composite control method for a carriage balancing single inverted pendulum system is proposed and applied to swing up the pendulum and to stabilize it under the state constraint. The target inverted pendulum system has an extremely limited length of the cart(below 16cm). The proposed swing-up controller comprises a sliding mode control algorithm and an optimal control algorithm based on two regions: the region near the inverted unstable equilibrium position and the rest of the state space including the downward stable equilibrium position. The sliding mode controller uses a switching control action to converge along the specified path(hyperplane) derived from energy equation from a state around the path to desired state(standing position). An optimal control method is also used to guarantee the stability at unstable equilibrium position. Compared with the reported controllers, it is simpler and easier to implement. Experimental results are given to show the effectiveness of this controller.