Purpose $[^{11}C]$acetate has been proved useful in detecting the myocardial oxygen metabolism and various malignancies including prostate cancer, hepatocellular carcinoma, renal cell carcinoma and brain tumors. The purpose of study was to improve the radiosynthesis yield of $[^{11}C]$acetate on a automated radiosynthesis module. Materials and Methods $[^{11}C]$acetate was prepared by carboxylation of grignard reagent, methylmagnesium chloride, with $[^{11}C]$$CO_2$ gas, followed by hydrolysis with 1 mM acetic acid and purification using solid phase extraction cartridges. The effect of the reaction temperature ($0^{\circ}C$, $10^{\circ}C$, $-55^{\circ}C$) and cyclotron beam time (10 min, 15 min, 20 min, 25 min) on the radiosynthesis yield were investigated in the $[^{11}C]$acetate labeling reaction. Results The maximum radiosynthesis yield was obtained at $-10^{\circ}C$ of reaction temperature. The radioactivities of $[^{11}C]$acetate acquired at $-10^{\circ}C$ reaction temperature was 2.4 times higher than those of $[^{11}C]$acetate acquired at $-55^{\circ}C$. Radiosynthesis yield of $[^{11}C]$acetate increased with increasing cyclotron beam time. Conclusion This study shows that radiosynthesis yield of $[^{11}C]$acetate highly dependent on reaction temperature. The best radiosynthesis yield was obtained in reaction of grignard reagent with $[^{11}C]$$CO_2$ at $-10^{\circ}C$. This radiolabeling conditions will be ideal for routine clinical application.
Lee, Ji Hyeon;Jung, Sang Hyung;Kim, Jun Ho;Min, Eun Joo;Yeo, Un Yeong;Kim, Jong Woo
Journal of Intelligence and Information Systems
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v.26
no.1
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pp.97-117
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2020
Product evaluation criteria is an indicator describing attributes or values of products, which enable users or manufacturers measure and understand the products. When companies analyze their products or compare them with competitors, appropriate criteria must be selected for objective evaluation. The criteria should show the features of products that consumers considered when they purchased, used and evaluated the products. However, current evaluation criteria do not reflect different consumers' opinion from product to product. Previous studies tried to used online reviews from e-commerce sites that reflect consumer opinions to extract the features and topics of products and use them as evaluation criteria. However, there is still a limit that they produce irrelevant criteria to products due to extracted or improper words are not refined. To overcome this limitation, this research suggests LDA-k-NN model which extracts possible criteria words from online reviews by using LDA and refines them with k-nearest neighbor. Proposed approach starts with preparation phase, which is constructed with 6 steps. At first, it collects review data from e-commerce websites. Most e-commerce websites classify their selling items by high-level, middle-level, and low-level categories. Review data for preparation phase are gathered from each middle-level category and collapsed later, which is to present single high-level category. Next, nouns, adjectives, adverbs, and verbs are extracted from reviews by getting part of speech information using morpheme analysis module. After preprocessing, words per each topic from review are shown with LDA and only nouns in topic words are chosen as potential words for criteria. Then, words are tagged based on possibility of criteria for each middle-level category. Next, every tagged word is vectorized by pre-trained word embedding model. Finally, k-nearest neighbor case-based approach is used to classify each word with tags. After setting up preparation phase, criteria extraction phase is conducted with low-level categories. This phase starts with crawling reviews in the corresponding low-level category. Same preprocessing as preparation phase is conducted using morpheme analysis module and LDA. Possible criteria words are extracted by getting nouns from the data and vectorized by pre-trained word embedding model. Finally, evaluation criteria are extracted by refining possible criteria words using k-nearest neighbor approach and reference proportion of each word in the words set. To evaluate the performance of the proposed model, an experiment was conducted with review on '11st', one of the biggest e-commerce companies in Korea. Review data were from 'Electronics/Digital' section, one of high-level categories in 11st. For performance evaluation of suggested model, three other models were used for comparing with the suggested model; actual criteria of 11st, a model that extracts nouns by morpheme analysis module and refines them according to word frequency, and a model that extracts nouns from LDA topics and refines them by word frequency. The performance evaluation was set to predict evaluation criteria of 10 low-level categories with the suggested model and 3 models above. Criteria words extracted from each model were combined into a single words set and it was used for survey questionnaires. In the survey, respondents chose every item they consider as appropriate criteria for each category. Each model got its score when chosen words were extracted from that model. The suggested model had higher scores than other models in 8 out of 10 low-level categories. By conducting paired t-tests on scores of each model, we confirmed that the suggested model shows better performance in 26 tests out of 30. In addition, the suggested model was the best model in terms of accuracy. This research proposes evaluation criteria extracting method that combines topic extraction using LDA and refinement with k-nearest neighbor approach. This method overcomes the limits of previous dictionary-based models and frequency-based refinement models. This study can contribute to improve review analysis for deriving business insights in e-commerce market.
This study has analyzed whether the virtuous cycle of value-added between the processes within the company has formed and whether the virtuous ecosystem between the processes within the industry has been built through the analysis of value chain(VC) and value system(VS) targeting the Korean photovoltaic companies. For a study method, after conducting a survey on the companies, a regression analysis was performed on the causal relationship between the process within the VC and VS. Based on the results of the analysis, for the VC of the Korean photovoltaic industry, an increase in the R&D support from the government has led to the increase in the investment of R&D for the related industry, and the increase in the investment of R&D has contributed to the increase in the growth of its productivity, and the growth in the productivity of R&D has influenced the increase in the production of solar products. In addition, the reduction of photovoltaic production cost for the company has influenced the increase of recurring profit margin compared to the sales. However it was shown that the increase in the company's production volume does not contribute to the reduction of production cost. Meanwhile, the increase in recurring profit margin compared to the sales were influencing the increase in the production volume but it was shown that the increase in the company's investment of R&D was not a contributing factor thus it was not included in the virtuous cycle. It was analyzed that the VS was shown not to influence all other processes within the industry except for the module companies where the increase in the recurring profit margin compared to the sales was influenced by the increase in the recurring profit margin compared to the sales of solar cell companies. This shows that the virtuous industrial ecosystem which should be made under the mutual cooperation by the ingot, wafer, solar cell, module and system companies are yet incomplete.
Habitat creation for endangered species Menyanthes trifoliata L. using planting module represents a habitat type such as the rhizome grows horizontally to open water at the margin of the lake. The objectives of this mesocosm experiment are habitat creation with easy construction and low management effort, and to investigate the potential of providing a habitat for aquatic macroinvertebrates. Planting modules had three different substrates of bed soil, perlite and K-SOIL (artificial lightweight soil using bottom ash). These modules were established in two different size of the tub($1170{\times}2250{\times}300mm^3$, $900{\times}1360{\times}190mm^3$). According to the monitoring results, number of leaves and coverage of M. trifoliata showed significant difference with substrate and tub size. The number of leaves showed similar growth responses in bed soil (mean 22.979) and K-SOIL (mean 28.042) substrates but growth was poor in perlite substrate (mean 1.667). The number of leaves in the large tub was more than small tub (p=0.015). Similar responses were obtained with the coverage, the length of rhizome and the number of rhizome in M. trifoliata. A total of 21 taxa of aquatic macroinvertebrates including 1,145 individuals was found in the mesocosm. The Shannon diversity index and colonization index in the mesocosm were similar to the previous studies. These results suggest that the experimental mesocosm could provide sufficient habitats for aquatic macroinvertebrates. If planting modules use bed soil or K-SOIL by planting substrate, establish that taking into account open water surfaces for M. trifoliata growth and manage about 30cm of water depth control, then habitat creation for M. trifoilata will be successful.
Journal of the Institute of Electronics Engineers of Korea SD
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v.47
no.9
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pp.14-23
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2010
This paper reports the fabrication of a DVB-T/H System in Package (SiP) that is able to receive and process the DVB-T/H signal. The DVB-T/H is the European telecommunication standard for Digital Video Broadcasting (DVB). An IC-embedded Printed Circuit Board (PCB) process, interpose a chip between PCB layers, has applied to the DVB-T/H SiP. The chip inserted in DVB-T/H SiP is the System on Chip (SoC) for mobile TV. It is comprised of a RF block for DVB-T/H RF signal and a digital block to convert received signal to digital signal for an application processor. To operate the DVB-T/H IC, a 3MHz DC-DC converter and LDO are on the DVB-T/H SiP. And a 38.4MHz crystal is used as a clock source. The fabricated DVB-T/H SiP form 4 layers which size is $8mm{\times}8mm$. The DVB-T/H IC is located between 2nd and 3rd layer. According to the result of simulation, the RF signal sensitivity is improved since the layout modification of the ground plane and via. And we confirmed the adjustment of LC value on power transmission is necessary to turn down the noise level in a SiP. Although the size of a DVB-T/H SiP is decreased over 70% than reference module, the power consumption and efficiency is on a par with reference module. The average power consumption is 297mW and the efficiency is 87%. But, the RF signal sensitivity is declined by average 3.8dB. This is caused by the decrease of the RF signal sensitivity which is 2.8dB, because of the noise from the DC-DC converter.
Journal of Korean Society of Environmental Engineers
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v.36
no.4
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pp.295-302
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2014
This study demonstrates a double-path CDI as an alternative of advanced wastewater treatment process. While the CDI typically consists of many pairs of electrodes connected in parallel, the new double-path CDI is designed to have series flow path by dividing the module into two stages. The CFD model showed that the double-path had uniform flow distribution with higher velocity and less dead zone compared with the single-path. However, the double-path was predicted to have higher pressure drop(0.7 bar) compared the single-path (0.4 bar). From the unit cell test, the highest TDS removal efficiencies of single- and double-path were up to 88% and 91%, respectively. The rate of increase in pressure drop with an increase of flow rate was higher in double-path than single-path. At 70 mL/min of flow rate, the pressure drop of double-path was 1.67 bar, which was two times higher than single-path. When the electrode spacing was increased from 100 to $200{\mu}m$, the pressure drop of double-path decreased from 1.67 to 0.87 bar, while there was little difference in TDS removal. When proto type double-path CDI was operated using sewage water, TDS, $NH_4{^+}$-N, $NO_3{^-}$-N and $PO_4{^{3-}}$-P removal efficiencies were up to 78%, 50%, 93% and 50%, respectively.
In this paper, we present relative positioning algorithm for moving land vehicle using GPS, MEMS IMU and B-CDMA module. This algorithm does not calculate precise absolute position but calculates relative position directly, so additional infrastructure and I2V communication device are not required. Proposed algorithm has several steps. Firstly, unbiased relative position is calculated using pseudorange difference between two vehicles. Simultaneously, the algorithm estimates position of each vehicle using GPS/INS integration. Secondly, proposed algorithm performs filtering and finally estimates relative position and relative velocity. Using proposed algorithm, we can obtain more precise relative position for moving land vehicles with short time interval as IMU sensor has. The simulation is performed to evaluate this algorithm and the several field tests are performed with real time program and miniature vehicles for verifying performance of proposed algorithm.
Journal of the Institute of Electronics Engineers of Korea CI
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v.48
no.3
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pp.1-10
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2011
Social network service is defined as an online service or communication service based on social relations among people applied the concept of social network. Social collaborative service included in social network service is characterized by the new value of modified content or recreated content made through collaborative creation process between members of the group. It has the remarkable merits such as sharing and collaboration. But, at the same time, it has the latent problems such as content reuse or copy that is not allowed for members to use. It has been emerged that UCC which is a typical example of recreated or modified content has the copyright issues in both creation and publishing step. To resolve this matter, we don't have many appropriate methods except CCL so far. So, in this paper, we define the problem and implement the UCC metadata manager to control metadata reflecting the feature of UCC. We draw the reference metadata element to identify original content utilized re-creation process. After that we define the R.Metadata Loader module based on the use case. Finally, the proposed UCC metadata manager provides the information of referenced content and lets us to identify the relationship between reference contents. So as to implement prototype, we use Kaltura which is CMS using open source and obtain functional extensibility of metadata manager by using open API.
The objectives of this study were to access climate change by global warming in Korea, and to investigate its effects on production efficiency of lactating dairy cows. Two regions, Daegu and Daekwanryung, were selected to represent a warm and a cold area, respectively. Time-series analyses on meteorological records for 25 years (from January 1, 1988 to December 31, 2012) revealed significant and different climate changes in two regions. In the warm area there has been a significant (P<0.05) increase in low temperature during the summer, which can cause heat stress to the animal. On the other hand, a decrease in low temperature during the winter was observed in the cold region (P<0.01), and cold stress in winter can thus be an issue in this region. Simulations using a model integrated the Korean feeding standard for dairy cattle and the environmental effect module of Cornell Net Carbohydrate and Protein System, indicated that a reduction in feed efficiency can be a problem during the winter in the cold region while during the summer in the warm area. We conclude that the effect of climate change by global warming varies in different areas in Korea and a region-specific management strategy should be developed in order to maintain productivity, health and welfare of lactating dairy cows.
To analyze travel demand fur transportation policy and transportation planning, it is important to construct realistic and reliable traffic data. And it needs a user friendly system to demonstrate transportation problems in the transportation planning and transportation management aspect. Generally, to construct network for analysis and collection about social and economical data is a core of transportation planning model. However, it takes a lot of time and effect. To overcome this problem GIS is more effective and efficient in data processing, such as selecting, editing and visualizing, etc. However, it is an early stage to use CIS in the transportation problems. This paper shows a new GIS-T system. The system can give traffic information and plan transportation planning using GIS which has ability as spatial representation and spatial analysis. To build this system, we design interfaces that are able to communicate transportation package for analysis with GIS and manage network efficiently, such as editing and examination. And we also develop a module for traffic information processing to handle spatial data and add it on the system. The proposed system shows more realistic transportation network modeling because the system presents more effective conditions to analyze network. And it can be a tool that can analyze various transportation problems.
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