• 한국환경과학회지
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• 제24권5호
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• pp.679-687
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• 2015

Atmospheric aerosol particles were investigated at GNTECH university in Jinju city. Samples were collected using the Nanosampler period from January to December 2014. The Nanosampler is a 6 stage cascade impactor(1 stage : > $10{\mu}m$, 2 stage : $2.5{\sim}10{\mu}m$, 3 stage : $1.0{\sim}2.5{\mu}m$, 4 stage : $0.5{\sim}10{\mu}m$, 5 stage : $0.1{\sim}0.5{\mu}m$, back-up : < $0.1{\mu}m$) with the stages having 50% cut-off ranging from 0.1 to $10{\mu}m$ in aerodynamic diameter. The mass size distribution of Atmospheric aerosol particles was unimodal with peak at $1.0{\sim}2.5{\mu}m$ or $0.5{\sim}1.0{\mu}m$. The annual average concentrations of TSP, $PM_{10}$, $PM_{2.5}$, $PM_1$, $PM_{0.5}$ and $PM_{0.1}$ were $44.0{\mu}g/m^3$, $40.3{\mu}g/m^3$, $31.4{\mu}g/m^3$, $18.0{\mu}g/m^3$, $8.0{\mu}g/m^3$, $3.0{\mu}g/m^3$, respectively. On average $PM_{10}$, $PM_{2.5}$, $PM_1$, $PM_{0.5}$ and $PM_{0.1}$ make up 0.91, 0.70, 0.41, 0.19 and 0.07 of TSP, respectively. The annual average of $PM_{2.5}/PM_{10}$ ratio was 0.77.

• Journal of the Korean Statistical Society
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• 제36권2호
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• pp.285-297
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• 2007

We consider the $P_{\lambda}^M-service$ policy for an M/G/1 queueing system in which the workload is monitored randomly at discrete points in time. If the level of the workload exceeds a threshold ${\lambda}$ when it is monitored, then the service rate is increased from 1 to M instantaneously and is kept as M until the workload reaches zero. By using level-crossing arguments, we obtain explicit expressions for the stationary distribution of the workload in the system.

• 대한화학회지
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• 제54권1호
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• pp.59-64
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• 2010

일련의 불소화된 티아디아졸 3, 트리아졸 4, 그리고 옥사디아졸 5이 (2-(6-Methyl-2-P-tolyl-lH-imidazo[1,2-a]pyridin-3-yl)핵종을 가지고 있는 티오세미카르바지드로 부터 합성되어진다. 초음파조사 방법 뿐만 아니라 일반적인 방법에 의해 반응이 진행되었다. 모든 생성물들은 IR, 1H NMR, MS로 구조가 결정되었고, 이들 화합물의 항균활성을 스크닝하였다.

• 고무기술
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• 제6권2호
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• pp.91-98
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• 2005

Nano-sized cathode materials for high power lithium ion polymer battery are easily and economically prepared using united eutectic self-mixing method without any artificial mixing procedures of reactants and ultra-miniaturization of products. While the micro-sized $LiNi_{0.7}Co_{0.3}O_2$ exhibits the discharge capacities of 167.8 mAh/g at 0.1C and 142.5 mAh/g at 3.0C, those of the nano-sized $LiNi_{0.7}Co_{0.3}O_2$ are 170.8 mAh/g at 0.1C and 159.3 mAh/g at 3.0C. In the case of $LiCoO_2$, the micro-sized $LiCoO_2$ exhibits the discharge capacities of 134.8 mAh/g at 0.1C and 118.6 mAh/g at 5.0C. Differently, the nano-sized $LiCoO_2$ exhibits the discharge capacities of 137.2 mAh/g at 0.1C and 131.7 mAh/g at 5.0C.

• 호남수학학술지
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• 제39권3호
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• pp.431-442
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• 2017

For a quadrilateral P, we consider the centroid $G_0$ of the vertices of P, the perimeter centroid $G_1$ of the edges of P and the centroid $G_2$ of the interior of P, respectively. We denote by M the intersection point of two diagonals of P. If P is a parallelogram, then we have $G_0=G_1=G_2=M$. Conversely, one of $G_0=M$ and $G_2=M$ implies that P is a parallelogram. In this paper, we show that $G_1=M$ is also a characteristic property of parallelograms.

• 대한수학회논문집
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• 제21권1호
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• pp.185-191
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• 2006

This paper observes that the induced homomorphisms on cohomology groups by a cyclic map are trivial. For a CW-complex X, we use the fact to obtain some conditions of X so that the n-th Gottlieb group $G_n(X)$ is trivial for an even positive integer n. As corollaries, for any positive integer m, we obtain $G_{2m}(S^{2m})\;=\;0\;and\;G_2(CP^m)\;=\;0$ which are due to D. H. Gottlieb and G. Lang respectively, where $S^{2m}$ is the 2m- dimensional sphere and $CP^m$ is the complex projective m-space. Moreover, we show that $G_4(HP^m)\;=\;0\;and\;G_8(II)\;=\;0,\;where\;HP^m$ is the quaternionic projective m-space for any positive integer m and II is the Cayley projective space.

• 한국환경성돌연변이발암원학회지
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• 제24권3호
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• pp.128-136
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• 2004

CYP1A1 is known to be inducible by xenobiotic compouds such as polyciclic aromatic hydrocarbons(PAHs) and 2,3,7,8-tetrachloro-dibenzo-p-dioxin(TCDD). These chemicals have been identified worldwide and can have a significant impact on the human health and well being of human and wildlife. Given these issues, the detection and quantification of these chemicals in biological, environmental and food samples is important. First, we investigated the effect of on CYP1A1 promoter activity, 7-ethoxyresorufin-O-deethylase(EROD) activity and CYP1A1 mRNA expression induced by benzo(k)fluoranthene(B(k)F) in MCF-7 cells. We found that B(k)F significantly up-regulates the level of CYP1A1 prompter activity, EROD and CYP1A1 mRNA. When cells were treated with genistein, it was not changed that EROD and CYP1A1 mRNA, compared to that of control. However, genistein inhibited the B(k)F-induced CYP1A1 promoter activity and mRNA level at high concentration. Furthermore, in this study, effects of HDAC(histone deacetvlase) inhibitors on human prostate cancer cells proliferation were examined. HC-toxin, SAHA and TSA inhibited cell proliferation in PC3 cells. A novel HDAC inhibitor, IN2001 also suppressed the growth of PC3 cells. And IN2001 and SAHA increased S phase and G2/M phase at 12 hrs treatment but cells were arrested G0/G1 phase at 45 hrs treatment. The HC-toxin treatment for 24 hrs and 48 hrs increased G0/G1 at low concentration ($0.1\mu\textrm{m}$) but increased G2/M at more than concentration of $1\mu\textrm{m}$. TSA increased G2/M phase. These findings height the possbility of developing HDAC inhibitors as potential anticancer therapeutic agents for the treatment of prostate cancer.

• Asian Pacific Journal of Cancer Prevention
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• 제15권9호
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• pp.4101-4107
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• 2014

Protein phosphatase 1 (PP1) is a major serine/threonine phosphatase that controls gene expression and cell cycle progression. The active mutant IPP5 ($8-60hIPP5^m$), the latest member of the inhibitory molecules for PP1, has been shown to inhibit the growth of human cervix carcinoma cells (HeLa). In order to elucidate the underlying mechanisms, the present study assessed overexpression of $8-60hIPP5^m$ in HeLa cells. Flow cytometric and biochemical analyses showed that overexpression of $8-60hIPP5^m$ induced G2/M-phase arrest, which was accompanied by the upregulation of cyclin B1 and phosphorylation of G2/M-phase proteins ATM, p53, $p21^{cip1/waf1}$ and Cdc2, suggesting that $8-60hIPP5^m$ induces G2/M arrest through activation of the ATM/p53/$p21^{cip1/waf1}$/Cdc2/cyclin B1 pathways. We further showed that overexpression of $8-60hIPP5^m$ led to delayed nuclear translocation of cyclin B1. $8-60hIPP5^m$ also could translocate to the nucleus in G2/M phase and interact with $pp1{\alpha}$ and Cdc2 as demonstrated by co-precipitation assay. Taken together, our data demonstrate a novel role for $8-60hIPP5^m$ in regulation of cell cycle in HeLa cells, possibly contributing to the development of new therapeutic strategies for cervix carcinoma.

• 한국농림기상학회지
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• 제7권2호
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• pp.141-147
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• 2005

본 연구는 강원도 춘천지역의 산성장하물중 습성강하물의 농도와 침착량을 산정하고, 대기오염도의 측정과 함께 가로수로 식재되어 있는 은행나무의 계절적 엽중산도와 수용성황함량의 변화를 조사하여, 대기오염과 수목의 생리적 변화를 통해 환경영향평가로서의 수목의 역할을 알아보는데 그 목적이 있다. 계절별 춘천지역의 대기오염도, 산성강하물의 농도와 침착량, 은행나무의 생리적 변화는 다음과 같이 조사되었다. $SO_2$농도는 연평균 0.004ppm으로 전국 연평균 0.006ppm과 비교해 보았을 때 다소 낮은 수치를 나타냈으며, 계절별 $SO_2$의 농도는 겨울 0.007ppm, 봄 0.004ppm, 여름 0.003ppm, 가을 0.004ppm으로 측정되었고, $NO_2$의 농도는 연평균 0.013ppm으로 전국 연평균 0.024ppm과 비교해 보았을 때 다소 낮은 수치를 나타냈으며, 계절별 $NO_2$의 농도는 겨울에 0.024ppm, 봄에 0.020ppm, 여름에 0.013ppm, 가을에 0.017ppm으로 측정되었다 $PM_{10}$ 경우에는 $66{\mu}g/m^3$으로 나타나 전국 연평균농도 $56{\mu}g/m^3$에 비해 다소 높은 수치를 보였으며, 계절별로는 겨울에 $587.64{\mu}g/m^3$, 봄에 $82.14{\mu}g/m^3$, 여름에 $48.34{\mu}g/m^3$, 가을에 $46.03{\mu}g/m^3$으로 측정되었다. 산성강하물의 주요 이온인 $SO_4\;^{2-},\;NO_3^-,\;Cl^-,\;NH_4\;^+$의 연평균 농도는 각각 3.584 mg/l, 2.803 mg/l, 1.485 mg/l, 0.998 m/l를 보이고 있는데, $SO_4\;^{2-}$는 5.135 mg/l의 농도를 보인 겨울에 가장 높은 값을, 봄에 2.156mg/l 가장 낮은 값을 보였으며, $NO_3^-$의 경우에도 3.875mg/l의 농도를 보인 겨울에 가장 높은 값을, 봄에 1.586mg/l로 가장 낮은 값을 나타났고 $Cl^-$의 경우 여름에 2.559mg/l로 가장 높은 값을, 겨울에 0.820mg/l로 가장 낮은 값을 나타냈다. $NH_4^+$의 경우에는 1.284mg/l를 보인 여름에 가장 높은 값을, 봄에 0.653mg/l로 가장 낮은 값을 보였다. 산성(습성)강하물의 연간 침착량을 살펴보면 $SO_4^{2-}\;3.865g/m^2/yr,\;NO_3^-\;2.924g/m^2/yr,\;Cl^-\;2.773g/m^2/yr,\;NH_4^\;+1.485g/m^2/yr$이 조사기간 동안 침착되었고, 계절별로는 여름철에 강수가 집중됨으로서 습성강하물 침착량이 총량적으로 증가하였으며, 그 값은 $SO_4^{2-}\;2.118g/m^2/season,\;NO_3^-\;1.509g/m^2/season,\;Cl^-\;2.185g/m^2/season,\;NH_4\;^+\;1.096g/m^2/season$로. 나타났다. 계절별 잎의 평균 pH의 변화는 봄 pH $5.9\pm0.5$, 여름 pH $5.5\pm0.4$, 가을 pH $5.1\pm0.3$을 나타내었고, 엽중 수용성 황함량의 계절별 평균값은 봄 $0.012\pm0.004\%$, 여름 $0.012\pm0.002\%$, 가을 $0.020\pm0.007\%$ 수준을 보이고 있다. 수피 내 함유되어 있는 수용성 황함량의 계절별 평균값은 봄 $0.0071\pm0.0003\%$, 여름 $0.0066\pm0.0004\%$, 가을 $0.0063\pm0.0004\%$, 겨울 $0.0071\pm0.0003\%$ 수준을 나타냈다.

• 대한수학회보
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• 제44권4호
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• pp.623-629
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• 2007

In this paper, we study the uniqueness of entire functions and prove the following result: Let f and g be two nonconstant entire functions, n, m be positive integers. If $f^n(f^m-1)f#\;and\;g^n(g^m-1)g#$ share 1 IM and n>4m+11, then $f{\equiv}g$. The result improves the result of Fang-Fang.