• Proceedings of the Korean Society for Bioinformatics Conference
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• 2005.09a
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• pp.431-436
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• 2005

Living cells are sustained not by individual activities but rather by coordinated summative efforts of different biological functional modules. While recent research works have focused largely on finding individual functional modules, this paper attempts to explore the connections or relationships between different cellular functions through cross-function domain interaction maps. Exploring such a domain interaction map can help understand the underlying inter-function communication mechanisms. To construct a cross-function domain interaction map from existing genome-wide protein-protein interaction datasets, we propose a two-step procedure. First, we infer conserved domain-domain interactions from genome-wide protein-protein interactions of yeast, worm and fly. We then build a cross-function domain interaction map that shows the connections of different functions through various conserved domain interactions. The domain interaction maps reveal that conserved domain-domain interactions can be found in most detected cross-functional relationships and a f9w domains play pivotal roles in these relationships. Another important discovery in the paper is that conserved domains correspond to highly connected protein hubs that connect different functional modules together.

• Journal of Life Science
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• v.14 no.6 s.67
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• pp.997-1002
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• 2004

This paper deals with the WASPIFA (Web-based Assistant System for Protein-protein Interaction and Function Analysis) system that can provide the comprehensive information on Protein-protein interaction and function concerned with function analysis. Different from existing systems for protein function and protein-protein interaction analysis, which provide fragmentary information restricted to specific field, our system furnishes end-user with comprehensive and synthetic information on the input sequence to be analyzed, including function and annotation information, domain information, and interaction relationship information. The synthetic information that our system contains as local databases has been extracted from many resources related to function, annotation, motif and domain by various pre-processing. Employing our system, end-users can evaluate and judge the synthetic results to do protein interaction and function analysis effectively. In addition, the WASPIFA system is equipped with automatic system management and data update function that facilitates system manager to maintain and manage it efficiently.

• The Journal of the Korea Contents Association
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• v.6 no.2
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• pp.93-98
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• 2006

The paper describes a method o( user feedback in order to enhance the retrieval system effectiveness. The existing fuzzification function adapting fuzzy technique has difficulty that 4 type graph is made each time user select components. In this paper, to overcome this weak point of feedback, we proposed the interaction function using gaussian function that gives different learning rate according to choice of components with same function. We suggest the most efficient dynamic interaction function based on comparison of retrieval performance according to parameter of function. And then, we will construct the efficient retrieval system.

• Interaction and multiscale mechanics
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• v.5 no.3
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• pp.287-318
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• 2012

We apply a partitioned-solution (iterative-staggered) coupling method based on a fixed Eulerian mesh with the level set function to a large-deformation fluid-structure interaction (FSI) problem where a large-deformable thin structure moves in a high-speed flow field, as an airbag does during deployment. This method combines advanced fluid and structure solvers-specifically, the constrained interpolation profile finite element method (CIP-FEM) for fluid Eulerian mesh and large-deformable structural elements for Lagrangian structural mesh. We express the large-deformable interface as a zero isosurface by the level set function, and introduce virtual nodes with level sets and structural normal velocities to generate the level set function according to the large-deformable interfacial geometry and enforce the kinematic condition at the interface. The virtual nodes are located in the direction normal to the structural mesh. It is confirmed that application of the method to unfolded airbag deployment simulation shows the adequacy of the method.

• The Pure and Applied Mathematics
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• v.19 no.2
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• pp.147-169
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• 2012

We introduce a Heaviside-function formulation of the interaction between incompressible two-phase fluid and a non-deformable solid. Fluid and solid interact in two ways : fluid satises the Dirichlet boundary condition imposed by the velocity field of solid, and solid is accelerated by the surface traction exerted by fluid. The two-way couplings are formulated by the Heaviside function to the interface between solid and fluid. The cumbersome treatment of interface is taken care of by the Heaviside function, and the interaction is discretized in a simple manner. The discretization results in a stable and accurate projection method.

• Proceedings of the KSR Conference
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• 2009.05b
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• pp.359-366
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• 2009

This paper aims for analyzing the vibration serviceability of train by simply expressing its vertical vibration when it passes a railway bridge. For this purpose, bridge-train transfer function was derived and bridge-train interaction analysis was performed by using the derived function. The bridge-train transfer function was developed with the assumption that train is a single mass-spring system, and bridge-train interaction analysis was performed on simple beams of KTX passenger car. The vertical acceleration signals of passenger cars obtained from bridge-train interaction analysis were compared with them of cars obtained from the bridge-train transfer function. As a result, it could be estimated to express the vertical vibration inside the passenger car required for vibration serviceability evaluation by using the vertical vibration of bridges obtained from moving load analysis. Therefore, it may be possible to evaluate the vibration serviceability of railway bridges considering bridge-train interaction effect.

• Journal of Korea Multimedia Society
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• v.8 no.5
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• pp.670-678
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• 2005

A Cellular Automaton(CA) is a dynamical system in which space and time are discrete, the state of each cell is unite and is updated by local interaction. Since the characteristics of CA is diffusion and local interaction, CA is used by crypto-systems and VLSI structure. In this study, we proposed a hash function based on the concept of 2-dimensional cellular automata and analyzed the proposed hash function.

• Journal of the Korean Society of Physical Medicine
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• v.5 no.4
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• pp.645-654
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• 2010

Purpose : The purpose of this study was to investigate changes in the gross motor function, self-esteem and social ability of children with cerebral palsy from group exercise program for physical and emotional interaction. Methods : Five cerebral palsy children who live in U city were recruited this study. Exercise sessions were held for 1 hour per session, once per week, for 12 consecutive weeks. At pre-treatment and post-treatment, subject were tested gross motor function measure, self-esteem and social ability. Results : After 12 weeks of paticipation in the group exercise program for physical and emotional interaction, there were improvements for gross motor function measure, self-esteem and social ability. Conclusion : Group exercise program for physical and emotional interaction can improve gross motor function, self-esteem and social ability.

• Journal of Applied Reliability
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• v.17 no.1
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• pp.28-37
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• 2017

Purpose: This paper proposes a procedure that may infer and identify interaction failures in a module. Methods: In design FMEA, we defined an interaction model between components and proposed a method for selecting a single component by using the standard specification classification table and four methods for choosing the related components. We also introduced the function tree for function and requirement characteristic analysis and proposed utilization of standard stress lists and 1st and 2nd stress analysis tables to determine the effect the stress analysis has on interactions. Finally, the interaction mechanism diagram was proposed and used to infer the failure mechanism. Process FMEA also established procedures in a similar way. Results: We established a procedure for predicting the failure mode due to interaction between components based on Company A's multi-step FMEA procedure. Conclusion: By applying the proposed interaction FMEA procedure to the development model, we were able to confirm the effect of the new derivation on the failure mode of interaction, which was not predicted by the existing FMEA.

• Bulletin of the Korean Chemical Society
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• v.34 no.12
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• pp.3727-3732
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• 2013

The interaction between metalloporphyrins and diazine tautomers was investigated using quantum chemistry method. The results showed that the metal atom in the metalloporphyrin was not coplanar with porphin ring, and zinc porphyrin has the most extent of its non-coplanar nature. The most stable complex in nine complexes was iron porphyrin. NBO analysis indicated that the interaction between the lone pair of electrons on the nitrogen atom and the unoccupied lone pair orbital of metal contributes significantly to the stability of the complexes. Through the conceptual DFT parameter and Fukui dual descriptor, the thermodynamic stability and reactivity of complexes were analyzed. The density difference function (DDF) analyzes were performed to explore the rearrangement of electronic density after the coordination interaction. NICS calculation indicated that metalloporphyrin aromaticity was reduced after the coordination interaction, and aromaticity of diazine tautomer was increased along direction vector of the coordination interaction force.