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http://dx.doi.org/10.5352/JLS.2004.14.6.997

Development of Web-Based Assistant System for Protein-Protein Interaction and Function Analysis  

Jung Min-Chul (Department of Microbiology, Kyungpook National University)
Park Wan (Department of Microbiology, Kyungpook National University)
Kim Ki-Bong (Department of Bioinformatics Engineering, Sangmyung University)
Publication Information
Journal of Life Science / v.14, no.6, 2004 , pp. 997-1002 More about this Journal
Abstract
This paper deals with the WASPIFA (Web-based Assistant System for Protein-protein Interaction and Function Analysis) system that can provide the comprehensive information on Protein-protein interaction and function concerned with function analysis. Different from existing systems for protein function and protein-protein interaction analysis, which provide fragmentary information restricted to specific field, our system furnishes end-user with comprehensive and synthetic information on the input sequence to be analyzed, including function and annotation information, domain information, and interaction relationship information. The synthetic information that our system contains as local databases has been extracted from many resources related to function, annotation, motif and domain by various pre-processing. Employing our system, end-users can evaluate and judge the synthetic results to do protein interaction and function analysis effectively. In addition, the WASPIFA system is equipped with automatic system management and data update function that facilitates system manager to maintain and manage it efficiently.
Keywords
Protein-protein interaction; WASPIFA system; domain; pre-processing; annotation information; domain; local database; automatic data update;
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